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Select item 105316671.

Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy

Hana Th. AlMajed, Mohamed Abu-Farha, Eman Alshawaf, Sriraman Devarajan, Zahra Alsairafi, Ashraf Elhelaly, Preethi Cherian, Irina Al-Khairi, Hamad Ali, Rose Mol Jose, Thangavel Alphonse Thanaraj, Ebaa Al-Ozairi, Fahd Al-Mulla, Abdulnabi Al Attar, Jehad Abubaker

Int J Mol Sci. 2023 Sep; 24(18): 14244. Published online 2023 Sep 18. doi: 10.3390/ijms241814244

PMCID:: PMC10531667

Abstract Article PDF–1.3M

Select item 104607322.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 101793603.

PAPP-A-Specific IGFBP-4 Proteolysis in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Daria A. Adasheva, Olga S. Lebedeva, Daria V. Goliusova, Alexander B. Postnikov, Maria V. Teriakova, Irina V. Kopylova, Maria A. Lagarkova, Alexey G. Katrukha, Daria V. Serebryanaya

Int J Mol Sci. 2023 May; 24(9): 8420. Published online 2023 May 8. doi: 10.3390/ijms24098420

PMCID:: PMC10179360

Abstract Article PDF–2.9M

Select item 95541874.

Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians

Yunhua L. Muller, Michael Saporito, Samantha Day, Khushdeep Bandesh, Cigdem Koroglu, Sayuko Kobes, William C. Knowler, Robert L. Hanson, Regeneron Genetics Center, Cristopher V. Van Hout, Alan R. Shuldiner, Clifton Bogardus, Leslie J. Baier

Eur J Hum Genet. 2022 Oct; 30(10): 1159–1166. Published online 2022 Jun 10. doi: 10.1038/s41431-022-01129-3

PMCID:: PMC9554187

Abstract Article PDF–959K

Select item 92316235.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 85051016.

The Rise of IGFBP4 in People with Obstructive Sleep Apnea and Multilevel Sleep Surgery Recovers Its Basal Levels

Abdulmohsen Alterki, Eman Al Shawaf, Irina Al-Khairi, Preethi Cherian, Devarajan Sriraman, Maha Hammad, Thangavel A. Thanaraj, Mahmoud A. K. Ebrahim, Fahd Al-Mulla, Mohamed Abu-Farha, Jehad Abubaker

Dis Markers. 2021; 2021: 1219593. Published online 2021 Oct 4. doi: 10.1155/2021/1219593

PMCID:: PMC8505101

Abstract Article PDF–721K

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 71604808.

CT‐IGFBP‐4 as a novel prognostic biomarker in acute heart failure

Alexey A. Konev, Alexey V. Kharitonov, Fedor N. Rozov, Evgeny P. Altshuler, Daria V. Serebryanaya, Johan Lassus, Veli‐Pekka Harjola, Alexey G. Katrukha, Alexander B. Postnikov

ESC Heart Fail. 2020 Apr; 7(2): 434–444. Published online 2020 Jan 22. doi: 10.1002/ehf2.12590

PMCID:: PMC7160480

Abstract Article PDF–776K

Select item 71360229.

Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence

Nicola Alessio, Tiziana Squillaro, Giovanni Di Bernardo, Giovanni Galano, Roberto De Rosa, Mariarosa AB Melone, Gianfranco Peluso, Umberto Galderisi

eLife. 2020; 9: e54523. Published online 2020 Mar 30. doi: 10.7554/eLife.54523

Correction in:: eLife. 2022; 11: e80871.

PMCID:: PMC7136022

Abstract Article PDF–3.3M

Select item 689109710.

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

Divya Achuthankutty, Roshan Singh Thakur, Peter Haahr, Saskia Hoffmann, Alexandros P. Drainas, Anna H. Bizard, Joachim Weischenfeldt, Ian D. Hickson, Niels Mailand

J Cell Biol. 2019 Dec 2; 218(12): 3943–3953. Published online 2019 Oct 15. doi: 10.1083/jcb.201905064

PMCID:: PMC6891097

Abstract Article PDF–2.7M

Select item 678801011.

Quantitative iTRAQ-based proteomic analysis of differentially expressed proteins in aging in human and monkey

Hao Wang, Xiaoqi Zhu, Junyan Shen, En-Feng Zhao, Dajun He, Haitao Shen, Hailiang Liu, Yongxin Zhou

BMC Genomics. 2019; 20: 725. Published online 2019 Oct 11. doi: 10.1186/s12864-019-6089-z

PMCID:: PMC6788010

Abstract Article PDF–1.5M

Select item 671572512.

Maximizing binary interactome mapping with a minimal number of assays

Soon Gang Choi, Julien Olivet, Patricia Cassonnet, Pierre-Olivier Vidalain, Katja Luck, Luke Lambourne, Kerstin Spirohn, Irma Lemmens, Mélanie Dos Santos, Caroline Demeret, Louis Jones, Sudharshan Rangarajan, Wenting Bian, Eloi P. Coutant, Yves L. Janin, Sylvie van der Werf, Philipp Trepte, Erich E. Wanker, Javier De Las Rivas, Jan Tavernier, Jean-Claude Twizere, Tong Hao, David E. Hill, Marc Vidal, Michael A. Calderwood, Yves Jacob

Nat Commun. 2019; 10: 3907. Published online 2019 Aug 29. doi: 10.1038/s41467-019-11809-2

PMCID:: PMC6715725

Abstract Article PDF–1.7M

Select item 615850813.

Loss of tumor suppressor IGFBP4 drives epigenetic reprogramming in hepatic carcinogenesis

Ying-Ying Lee, Myth TS Mok, Wei Kang, Weiqin Yang, Wenshu Tang, Feng Wu, Liangliang Xu, Mingfei Yan, Zhuo Yu, Sau-Dan Lee, Joanna H M Tong, Yue-Sun Cheung, Paul B S Lai, Dae-Yeul Yu, Qianben Wang, Grace L H Wong, Andrew M Chan, Kevin Y Yip, Ka-Fai To, Alfred S L Cheng

Nucleic Acids Res. 2018 Sep 28; 46(17): 8832–8847. Published online 2018 Jul 10. doi: 10.1093/nar/gky589

PMCID:: PMC6158508

Abstract Article PDF–8.5M

Select item 592582814.

Prognostic value of the Stanniocalcin-2/PAPP-A/IGFBP-4 axis in ST-segment elevation myocardial infarction

Germán Cediel, Ferran Rueda, Claus Oxvig, Teresa Oliveras, Carlos Labata, Oriol de Diego, Marc Ferrer, M. Cruz Aranda-Nevado, Judith Serra-Gregori, Julio Núñez, Cosme García, Antoni Bayes-Genis

Cardiovasc Diabetol. 2018; 17: 63. Published online 2018 Apr 30. doi: 10.1186/s12933-018-0710-3

PMCID:: PMC5925828

Abstract Article PDF–933K

Select item 545599615.

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers

Joseph Rosenbluh, Johnathan Mercer, Yashaswi Shrestha, Rachel Oliver, Pablo Tamayo, John G. Doench, Itay Tirosh, Federica Piccioni, Ella Hartenian, Heiko Horn, Lola Fagbami, David E. Root, Jacob Jaffe, Kasper Lage, Jesse S. Boehm, William C. Hahn

Cell Syst. Author manuscript; available in PMC 2017 Sep 28.

Published in final edited form as: Cell Syst. 2016 Sep 28; 3(3): 302–316.e4. doi: 10.1016/j.cels.2016.09.001

PMCID:: PMC5455996

Abstract Article PDF–3.1M

Select item 480956616.

Insulin-Like Growth Factor Binding Protein-4 as a Marker of Chronic Lupus Nephritis

Tianfu Wu, Chun Xie, Jie Han, Yujin Ye, Sandeep Singh, Jinchun Zhou, Yajuan Li, Huihua Ding, Quan-zhen Li, Xin Zhou, Chaim Putterman, Ramesh Saxena, Chandra Mohan

PLoS One. 2016; 11(3): e0151491. Published online 2016 Mar 28. doi: 10.1371/journal.pone.0151491