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Select item 108346631.

Downregulation of dermatopontin in cholangiocarcinoma cells suppresses CCL19 secretion of macrophages and immune infiltration

Peng Xu, Siyang Li, Ke Liu, Rui Fan, Fahui Liu, Haoxuan Zhang, Donghua Liu, Dongyan Shen

J Cancer Res Clin Oncol. 2024; 150(2): 66. Published online 2024 Feb 1. doi: 10.1007/s00432-023-05532-1

PMCID:: PMC10834663

Abstract Article PDF–6.2M

Select item 101995592.

CCL19/CCR7 drives regulatory T cell migration and indicates poor prognosis in gastric cancer

Danhua Xu, Xu Liu, Shouyu Ke, Yixian Guo, Chunchao Zhu, Hui Cao

BMC Cancer. 2023; 23: 464. Published online 2023 May 19. doi: 10.1186/s12885-023-10882-7

PMCID:: PMC10199559

Abstract Article PDF–1.4M

Select item 98669483.

Heparin Specifically Interacts with Basic BBXB Motifs of the Chemokine CCL21 to Define CCR7 Signaling

Marc Artinger, Oliver J. Gerken, Daniel F. Legler

Int J Mol Sci. 2023 Jan; 24(2): 1670. Published online 2023 Jan 14. doi: 10.3390/ijms24021670

PMCID:: PMC9866948

Abstract Article PDF–2.7M

Select item 92545734.

Structural Insights into Molecular Recognition by Human Chemokine CCL19

Eric M. Lewandowski, Kyle G. Kroeck, Lian M.C. Jacobs, Tyler G. Fenske, Robin N. Witt, Alyssa M. Hintz, Elizabeth R. Ramsden, Xiujun Zhang, Francis Peterson, Brian F. Volkman, Christopher T. Veldkamp, Yu Chen

Biochemistry. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Biochemistry. 2022 Mar 1; 61(5): 311–318. Published online 2022 Feb 14. doi: 10.1021/acs.biochem.1c00759

PMCID:: PMC9254573

Abstract Article PDF–1.7M

Select item 91349625.

CCL19 has potential to be a potential prognostic biomarker and a modulator of tumor immune microenvironment (TIME) of breast cancer: a comprehensive analysis based on TCGA database

Jinyan Wang, Dongmei Qin, Lingling Ye, Li Wan, Fen Wang, Yan Yang, Yajun Ma, Hui Yang, Zhaohui Yang, Meili Chen, Wen Jiang, Quan’an Zhang

Aging (Albany NY) 2022 May 15; 14(9): 4158–4175. Published online 2022 May 12. doi: 10.18632/aging.204081

PMCID:: PMC9134962

Abstract Article PDF–9.4M

Select item 84540336.

Low CCL19 expression is associated with adverse clinical outcomes for follicular lymphoma patients treated with chemoimmunotherapy

Yu Zhou, Shasha Wang, Yunxia Tao, Haizhu Chen, Yan Qin, Xiaohui He, Shengyu Zhou, Peng Liu, Jianliang Yang, Sheng Yang, Lin Gui, Ning Lou, Zhishang Zhang, Jiarui Yao, Xiaohong Han, Yuankai Shi

J Transl Med. 2021; 19: 399. Published online 2021 Sep 20. doi: 10.1186/s12967-021-03078-9

PMCID:: PMC8454033

Abstract Article PDF–3.8M

Select item 83232127.

IL-7 and CCL19-secreting CAR-T cell therapy for tumors with positive glypican-3 or mesothelin

Nengzhi Pang, Jingxuan Shi, Le Qin, Aiming Chen, Yuou Tang, Hainan Yang, Yufeng Huang, Qingde Wu, Xufeng Li, Bingjia He, Tianheng Li, Baoxia Liang, Jinglin Zhang, Bihui Cao, Manting Liu, Yunfei Feng, Xiaodie Ye, Xiaopei Chen, Lu Wang, Yu Tian, Hao Li, Junping Li, Hong Hu, Jingping He, Yuling Hu, Cheng Zhi, Zhaoyang Tang, Yibo Gong, Fangting Xu, Linfeng Xu, Weijun Fan, Ming Zhao, Deji Chen, Hui Lian, Lili Yang, Peng Li, Zhenfeng Zhang

J Hematol Oncol. 2021; 14: 118. Published online 2021 Jul 29. doi: 10.1186/s13045-021-01128-9

PMCID:: PMC8323212

Abstract Article PDF–2.5M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78350339.

IRF-1 contributes to the pathological phenotype of VSMCs during atherogenesis by increasing CCL19 transcription

Yongbin Shen, Zhanfeng Sun, Shuran Mao, Yingnan Zhang, Weiliang Jiang, Haitao Wang

Aging (Albany NY) 2021 Jan 15; 13(1): 933–943. Published online 2020 Nov 16. doi: 10.18632/aging.202204

PMCID:: PMC7835033

Abstract Article PDF–2.4M

Select item 716998310.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 703647511.

Lymphoidal chemokine CCL19 promoted the heterogeneity of the breast tumor cell motility within a 3D microenvironment revealed by a Lévy distribution analysis

Beum Jun Kim, Pimkhuan Hannanta-anan, Anders Ryd, Melody A Swartz, Mingming Wu

Integr Biol (Camb) 2020 Jan; 12(1): 12–20. Published online 2020 Feb 14. doi: 10.1093/intbio/zyaa001

PMCID:: PMC7036475

Abstract Article PDF–1012K

Select item 675317812.

Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7

Astrid S. Jørgensen, Olav Larsen, Edith Uetz-von Allmen, Michael Lückmann, Daniel F. Legler, Thomas M. Frimurer, Christopher T. Veldkamp, Gertrud M. Hjortø, Mette M. Rosenkilde

Front Immunol. 2019; 10: 2156. Published online 2019 Sep 13. doi: 10.3389/fimmu.2019.02156

PMCID:: PMC6753178

Abstract Article PDF–1.7M

Select item 658796213.

Adipose tissue expression of CCL19 chemokine is positively associated with insulin resistance

Shihab Kochumon, Fatema Al‐Rashed, Mohamed Abu‐Farha, Sriraman Devarajan, Jaakko Tuomilehto, Rasheed Ahmad

Diabetes Metab Res Rev. 2019 Feb; 35(2): e3087. Published online 2018 Nov 8. doi: 10.1002/dmrr.3087

PMCID:: PMC6587962

Abstract Article PDF–248K

Select item 615526214.

CCL19 suppresses angiogenesis through promoting miR-206 and inhibiting Met/ERK/Elk-1/HIF-1α/VEGF-A pathway in colorectal cancer

Zhuoqing Xu, Congcong Zhu, Chun Chen, Yaping Zong, Hao Feng, Di Liu, Wenqing Feng, Jingkun Zhao, Aiguo Lu

Cell Death Dis. 2018 Oct; 9(10): 974. Published online 2018 Sep 24. doi: 10.1038/s41419-018-1010-2

PMCID:: PMC6155262

Abstract Article PDF–4.0M

Select item 556595015.

Stimulation of osteoclast migration and bone resorption by C–C chemokine ligands 19 and 21

Jiyeon Lee, Cheolkyu Park, Hyung Joon Kim, Yong Deok Lee, Zang Hee Lee, Yeong Wook Song, Hong-Hee Kim

Exp Mol Med. 2017 Jul; 49(7): e358. Published online 2017 Jul 21. doi: 10.1038/emm.2017.100

PMCID:: PMC5565950

Abstract Article PDF–4.7M

Select item 543010216.

CCR7 mediates human breast cancer cell invasion, migration by inducing epithelial–mesenchymal transition and suppressing apoptosis through AKT pathway

Bing Xu, Minjie Zhou, Wencai Qiu, Jueming Ye, Qiming Feng

Cancer Med. 2017 May; 6(5): 1062–1071. Published online 2017 Apr 4. doi: 10.1002/cam4.1039

PMCID:: PMC5430102

Abstract Article PDF–577K

Select item 496702117.

Transferring the C-terminus of the chemokine CCL21 to CCL19 confers enhanced heparin binding

Austin J. Barmore, Sally M. Castex, Brittany A. Gouletas, Alex J. Griffith, Slater W. Metz, Nicolas G. Muelder, Michael J. Populin, David M. Sackett, Abigail M. Schuster, Christopher T. Veldkamp

Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Sep 2.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Sep 2; 477(4): 602–606. Published online 2016 Jun 21. doi: 10.1016/j.bbrc.2016.06.098

PMCID:: PMC4967021

Abstract Article PDF–567K

Select item 495897818.

Human breast cancer-derived soluble factors facilitate CCL19-induced chemotaxis of human dendritic cells

Hyundoo Hwang, Changsik Shin, Juhee Park, Enoch Kang, Bongseo Choi, Jae-A Han, Yoonkyung Do, Seongho Ryu, Yoon-Kyoung Cho

Sci Rep. 2016; 6: 30207. Published online 2016 Jul 25. doi: 10.1038/srep30207

PMCID:: PMC4958978

Abstract Article PDF–2.0M

Select item 480905019.

Solution structure of CCL19 and identification of overlapping CCR7 and PSGL-1 binding sites

Christopher T. Veldkamp, Eva Kiermaier, Skylar J. Gabel-Eissens, Miranda L. Gillitzer, David R. Lippner, Frank A. DiSilvio, Casey J. Mueller, Paeton L. Wantuch, Gary R. Chaffee, Michael W. Famiglietti, Danielle M. Zgoba, Asha A. Bailey, Yaya Bah, Samantha J. Engebretson, David R. Graupner, Emily R. Lackner, Vincent D. LaRosa, Tysha Medeiros, Michael L. Olson, Andrew J. Phillips, Harley Pyles, Amanda M. Richard, Scott J. Schoeller, Boris Touzeau, Larry G. Williams, Michael Sixt, Francis C. Peterson

Biochemistry. Author manuscript; available in PMC 2016 Jul 14.

Published in final edited form as: Biochemistry. 2015 Jul 14; 54(27): 4163–4166. Published online 2015 Jul 6. doi: 10.1021/acs.biochem.5b00560

PMCID:: PMC4809050

Abstract Article PDF–671K

Select item 442060820.

Up-regulation of galectin-9 induces cell migration in human dendritic cells infected with dengue virus

Yu-Lin Hsu, Mei-Yi Wang, Ling-Jun Ho, Chuan-Yueh Huang, Jenn-Haung Lai

J Cell Mol Med. 2015 May; 19(5): 1065–1076. Published online 2015 Mar 6. doi: 10.1111/jcmm.12500

PMCID:: PMC4420608

Abstract Article PDF–1.0M

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