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Items: 1 to 20 of 332

1.
Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth
Daniela De Zio, Francesca Molinari, Salvatore Rizza, Lucia Gatta, Maria Teresa Ciotti, Anna Maria Salvatore, Søs Grønbæk Mathiassen, Andrzej W. Cwetsch, Giuseppe Filomeni, Giuseppe Rosano, Elisabetta Ferraro
Cell Mol Life Sci. 2015 Nov; 72(21): 4173–4191. Published online 2015 May 15. doi: 10.1007/s00018-015-1927-x
PMCID:
PMC11113842
AbstractArticlePDF–1.8M
2.
Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala
Yoshifumi Matsumoto, Hideki Miwa, Kei-ichi Katayama, Arata Watanabe, Kazuyuki Yamada, Takashi Ito, Shinsuke Nakagawa, Jun Aruga
Front Mol Neurosci. 2024; 17: 1386924. Published online 2024 Apr 26. doi: 10.3389/fnmol.2024.1386924
PMCID:
PMC11082273
AbstractArticlePDF–4.8M
3.
Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology
Yeeun Yook, Kwan Young Lee, Eunyoung Kim, Simon Lizarazo, Xinzhu Yu, Nien-Pei Tsai
EMBO Rep. 2024 Mar; 25(3): 1233–1255. Published online 2024 Feb 27. doi: 10.1038/s44319-024-00090-0
PMCID:
PMC10933348
AbstractArticlePDF–3.8M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Nicole Fadahunsi, Jonas Petersen, Sophia Metz, Alexander Jakobsen, Cecilie Vad Mathiesen, Alberte Silke Buch-Rasmussen, Nigel Kurgan, Jeppe Kjærgaard Larsen, Rita C. Andersen, Thomas Topilko, Charlotte Svendsen, Mia Apuschkin, Grethe Skovbjerg, Jan Hendrik Schmidt, Grace Houser, Sara Elgaard Jager, Anders Bach, Atul S. Deshmukh, Tuomas O. Kilpeläinen, Kristian Strømgaard, Kenneth L. Madsen, Christoffer Clemmensen
Sci Adv. 2024 Mar 1; 10(9): eadg2636. Published online 2024 Mar 1. doi: 10.1126/sciadv.adg2636
PMCID:
PMC10906926
AbstractArticlePDF–6.4M
6.
Btbd11 supports cell-type-specific synaptic function
Alexei M. Bygrave, Ayesha Sengupta, Ella P. Jackert, Mehroz Ahmed, Beloved Adenuga, Erik Nelson, Hana L. Goldschmidt, Richard C. Johnson, Haining Zhong, Felix L. Yeh, Morgan Sheng, Richard L. Huganir
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112591. Published online 2023 May 31. doi: 10.1016/j.celrep.2023.112591
PMCID:
PMC10592477
AbstractArticlePDF–3.6M
7.
Uncovering a mammalian neural-specific poly(A) binding protein with unique properties
Sahil Sharma, Sam Kajjo, Zineb Harra, Benedeta Hasaj, Victoria Delisle, Debashish Ray, Rodrigo L. Gutierrez, Isabelle Carrier, Claudia Kleinman, Quaid Morris, Timothy R. Hughes, Roderick McInnes, Marc R. Fabian
Genes Dev. 2023 Aug 1; 37(15-16): 760–777. doi: 10.1101/gad.350597.123
PMCID:
PMC10546976
AbstractArticlePDF–5.4M
8.
Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex
Iva Salamon, Yongkyu Park, Terezija Miškić, Janja Kopić, Paul Matteson, Nicholas F. Page, Alfonso Roque, Geoffrey W. McAuliffe, John Favate, Marta Garcia-Forn, Premal Shah, Miloš Judaš, James H. Millonig, Ivica Kostović, Silvia De Rubeis, Ronald P. Hart, Željka Krsnik, Mladen-Roko Rasin
Nat Commun. 2023; 14: 6025. Published online 2023 Sep 27. doi: 10.1038/s41467-023-41730-8
PMCID:
PMC10533865
AbstractArticlePDF–4.9M
9.
TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb
Chunyu Cai, Qihui Luo, Lanlan Jia, Yu Xia, Xinting Lan, Xiaoli Wei, Shuai Shi, Yucong Liu, Yao Wang, Zongliang Xiong, Riyi Shi, Chao Huang, Zhengli Chen
Int J Mol Sci. 2023 Sep; 24(17): 13439. Published online 2023 Aug 30. doi: 10.3390/ijms241713439
PMCID:
PMC10487898
AbstractArticlePDF–7.5M
10.
Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice
Min Hu, Brittany Bodnar, Yonggang Zhang, Fangxin Xie, Fang Li, Siying Li, Jin Zhao, Ruotong Zhao, Naveen Gedupoori, Yifan Mo, Lanyi Lin, Xue Li, Wentong Meng, Xiaofeng Yang, Hong Wang, Mary F. Barbe, Shanthi Srinivasan, John R. Bethea, Xianming Mo, Hong Xu, Wenhui Hu
Int J Biol Sci. 2023; 19(10): 3226–3248. Published online 2023 Jun 19. doi: 10.7150/ijbs.78489
PMCID:
PMC10321293
AbstractArticlePDF–10M
11.
The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory
Sung-Hoon Kim, Jung-Hyun Choi, Laura Marsal-García, Mehdi Amiri, Akiko Yanagiya, Nahum Sonenberg
Proc Natl Acad Sci U S A. 2023 Jun 20; 120(25): e2300008120. Published online 2023 Jun 12. doi: 10.1073/pnas.2300008120
PMCID:
PMC10288579
AbstractArticlePDF–4.2M
12.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
13.
Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex
Martin Munz, Arjun Bharioke, Georg Kosche, Verónica Moreno-Juan, Alexandra Brignall, Tiago M. Rodrigues, Alexandra Graff-Meyer, Talia Ulmer, Stephanie Haeuselmann, Dinko Pavlinic, Nicole Ledergerber, Brigitte Gross-Scherf, Balázs Rózsa, Jacek Krol, Simone Picelli, Cameron S. Cowan, Botond Roska
Cell. 2023 Apr 27; 186(9): 1930–1949.e31. doi: 10.1016/j.cell.2023.03.025
PMCID:
PMC10156177
AbstractArticle
14.
KIF2A deficiency causes early-onset neurodegeneration
Nuria Ruiz-Reig, Georges Chehade, Janne Hakanen, Mohamed Aittaleb, Keimpe Wierda, Joris De Wit, Laurent Nguyen, Philippe Gailly, Fadel Tissir
Proc Natl Acad Sci U S A. 2022 Nov 15; 119(46): e2209714119. Published online 2022 Nov 7. doi: 10.1073/pnas.2209714119
PMCID:
PMC9674219
AbstractArticlePDF–3.8M
15.
Developmental disruption and restoration of brain synaptome architecture in the murine Pax6 neurodevelopmental disease model
Laura Tomas-Roca, Zhen Qiu, Erik Fransén, Ragini Gokhale, Edita Bulovaite, David J. Price, Noboru H. Komiyama, Seth G. N. Grant
Nat Commun. 2022; 13: 6836. Published online 2022 Nov 11. doi: 10.1038/s41467-022-34131-w
PMCID:
PMC9652404
AbstractArticlePDF–5.7M
16.
Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development
Seiya Yamada, Tomoya Mizukoshi, Akinori Tokunaga, Shin-ichi Sakakibara
PLoS Genet. 2022 Oct; 18(10): e1010438. Published online 2022 Oct 27. doi: 10.1371/journal.pgen.1010438
PMCID:
PMC9612522
AbstractArticlePDF–4.8M
17.
The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3
Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany
Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527
PMCID:
PMC9603860
AbstractArticlePDF–3.4M
18.
Early postnatal serotonin modulation prevents adult-stage deficits in Arid1b-deficient mice through synaptic transcriptional reprogramming
Hyosang Kim, Doyoun Kim, Yisul Cho, Kyungdeok Kim, Junyeop Daniel Roh, Yangsik Kim, Esther Yang, Seong Soon Kim, Sunjoo Ahn, Hyun Kim, Hyojin Kang, Yongchul Bae, Eunjoon Kim
Nat Commun. 2022; 13: 5051. Published online 2022 Aug 27. doi: 10.1038/s41467-022-32748-5
PMCID:
PMC9420115
AbstractArticlePDF–10M
19.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
20.
Isoflurane Disrupts Postsynaptic Density-95 Protein Interactions Causing Neuronal Synapse Loss and Cognitive Impairment in Juvenile Mice Via Canonical Nitric Oxide Mediated Protein Kinase-G Signaling
Swati Agarwal, Michele L. Schaefer, Caroline Krall, Roger A. Johns
Anesthesiology. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: Anesthesiology. 2022 Aug 1; 137(2): 212–231. doi: 10.1097/ALN.0000000000004264
PMCID:
PMC9332139
AbstractArticlePDF–3.2M

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