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Items: 1 to 20 of 51

1.
ALOX5AP suppresses osteosarcoma progression via Wnt/β-catenin/EMT pathway and associates with clinical prognosis and immune infiltration
Guo-Dong Han, Jian Dai, Hong-Xia Hui, Jing Zhu
J Orthop Surg Res. 2023; 18: 446. Published online 2023 Jun 22. doi: 10.1186/s13018-023-03919-x
PMCID:
PMC10286338
AbstractArticlePDF–9.7M
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
Key genes with prognostic values in suppression of osteosarcoma metastasis using comprehensive analysis
Mi Li, Xin Jin, Hao Li, Gang Wu, Shanshan Wang, Caihong Yang, Sisi Deng
BMC Cancer. 2020; 20: 65. Published online 2020 Jan 28. doi: 10.1186/s12885-020-6542-z
PMCID:
PMC6988291
AbstractArticlePDF–4.3M
4.
A 5-Lipoxygenase-Specific Sequence Motif Impedes Enzyme Activity and Confers Dependence on a Partner Protein
Erin E. Schexnaydre, Jana Gerstmeier, Ulrike Garscha, Paul M. Jordan, Oliver Werz, Marcia E. Newcomer
Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Apr; 1864(4): 543–551. Published online 2018 Oct 3. doi: 10.1016/j.bbalip.2018.09.011
PMCID:
PMC6369011
AbstractArticlePDF–1.3M
5.
Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population
Yilan Li, Xueming Xu, Dandan Zhang, Wei Cheng, Yanan Zhang, Bo Yu, Yao Zhang
Lipids Health Dis. 2019; 18: 25. Published online 2019 Jan 24. doi: 10.1186/s12944-019-0968-9
PMCID:
PMC6346589
AbstractArticlePDF–730K
6.
Association between the polymorphism (rs17222919, −1316T/G) of 5-lipoxygenase-activating protein gene (ALOX5AP) and the risk of stroke: A meta analysis
Hui Ye, Xin Zhang, Zupeng Chen, Xu Li, Tiehui Zhang, Chao Yang, Lifa Huang
Medicine (Baltimore) 2018 Oct; 97(41): e12682. Published online 2018 Oct 12. doi: 10.1097/MD.0000000000012682
PMCID:
PMC6203560
AbstractArticlePDF–682K
7.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
8.
Genetic Variants in the Transcriptional Regulatory Region of the ALOX5AP gene and Susceptibility to Ischemic Stroke in Chinese Populations
Dongzhi Yang, Xiangnan Huang, Chuanju Cui, Yuchao Zhang, Ya Li, Xin Zang, Ying He, Hong Zheng
Sci Rep. 2016; 6: 29513. Published online 2016 Jul 15. doi: 10.1038/srep29513
PMCID:
PMC4945871
AbstractArticlePDF–418K
9.
A Single Amino Acid Difference between Mouse and Human 5-Lipoxygenase Activating Protein (FLAP) Explains the Speciation and Differential Pharmacology of Novel FLAP Inhibitors
Jonathan M. Blevitt, Michael D. Hack, Krystal Herman, Leon Chang, John M. Keith, Tara Mirzadegan, Navin L. Rao, Alec D. Lebsack, Marcos E. Milla
J Biol Chem. 2016 Jun 10; 291(24): 12724–12731. Published online 2016 Apr 16. doi: 10.1074/jbc.M116.725325
PMCID:
PMC4933458
AbstractArticlePDF–2.5M
10.
5-Lipoxygenase-activating protein rescues activity of 5-lipoxygenase mutations that delay nuclear membrane association and disrupt product formation
Jana Gerstmeier, Marcia E. Newcomer, Sophie Dennhardt, Erik Romp, Jana Fischer, Oliver Werz, Ulrike Garscha
FASEB J. 2016 May; 30(5): 1892–1900. Published online 2016 Feb 3. doi: 10.1096/fj.201500210R
PMCID:
PMC4836370
AbstractArticle
11.
A Promoter Polymorphism (rs17222919, −1316T/G) of ALOX5AP Gene Is Associated with Decreased Risk of Ischemic Stroke in Two Independent Chinese Populations
Yujia Fan, Hui Chen, Aifan Li, Yunshu Shi, Yuchao Zhang, Qingchuan Feng, Yan Sun, Hong Zheng, Ying He
PLoS One. 2015; 10(3): e0122393. Published online 2015 Mar 27. doi: 10.1371/journal.pone.0122393
PMCID:
PMC4376390
AbstractArticlePDF–324K
12.
Interrelationships between ALOX5AP Polymorphisms, Serum Leukotriene B4 Level and Risk of Acute Coronary Syndrome
Guoping He, Shan Ye, Jingjiao Hui, Dandan Shen, Chuanping Qi, Lianhong Xu, Yichao Qian
PLoS One. 2014; 9(9): e106596. Published online 2014 Sep 11. doi: 10.1371/journal.pone.0106596
PMCID:
PMC4161330
AbstractArticlePDF–1.3M
13.
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis
Devaraj Basavarajappa, Min Wan, Ana Lukic, Dieter Steinhilber, Bengt Samuelsson, Olof Rådmark
Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31): 11371–11376. Published online 2014 Jul 17. doi: 10.1073/pnas.1410983111
PMCID:
PMC4128154
AbstractArticlePDF–1.1M
14.
5-Lipoxygenase Activating Protein (FLAP) Dependent Leukotriene Biosynthesis Inhibition (MK591) Attenuates Lipid A Endotoxin-Induced Inflammation
Wen-Feng Fang, Ivor S. Douglas, Chin-Chou Wang, Hsu-Ching Kao, Ya-Ting Chang, Chia-Cheng Tseng, Kuo-Tung Huang, Huang-Chih Chang, Meng-Chih Lin
PLoS One. 2014; 9(7): e102622. Published online 2014 Jul 15. doi: 10.1371/journal.pone.0102622
PMCID:
PMC4099325
AbstractArticlePDF–3.5M
15.
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)
C Pergola, J Gerstmeier, B Mönch, B Çalışkan, S Luderer, C Weinigel, D Barz, J Maczewsky, S Pace, A Rossi, L Sautebin, E Banoglu, O Werz
Br J Pharmacol. 2014 Jun; 171(12): 3051–3064. Published online 2014 May 27. doi: 10.1111/bph.12625
PMCID:
PMC4055205
AbstractArticlePDF–1.5M
16.
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease
Themistocles L. Assimes, Joshua W. Knowles, Jame s R. Priest, Analabha Basu, Kelly A. Volcik, Audrey Southwick, Holly K. Tabor, Jaana Hartiala, Hooman Allayee, Megan L. Grove, Raymond Tabibiazar, Stephen Sidney, Stephen P. Fortmann, Alan Go, Mark Hlatky, Carlos Iribarren, Eric Boerwinkle, Richard Myers, Neil Risch, Thomas Quertermous
Hum Genet. Author manuscript; available in PMC 2014 May 16.
Published in final edited form as: Hum Genet. 2008 May; 123(4): 399–408. Published online 2008 Mar 28. doi: 10.1007/s00439-008-0489-5
PMCID:
PMC4023692
AbstractArticlePDF–316K
17.
A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients
Suyoun Chung, Siew-Kee Low, Hitoshi Zembutsu, Atsushi Takahashi, Michiaki Kubo, Mitsunori Sasa, Yusuke Nakamura
Breast Cancer Res. 2013; 15(5): R81. Published online 2013 Sep 11. doi: 10.1186/bcr3475
PMCID:
PMC3978764
AbstractArticlePDF–282K
18.
A genome-wide association study for reading and language abilities in two population cohorts
M Luciano, D M Evans, N K Hansell, S E Medland, G W Montgomery, N G Martin, M J Wright, T C Bates
Genes Brain Behav. 2013 Aug; 12(6): 645–652. Published online 2013 Jun 20. doi: 10.1111/gbb.12053
PMCID:
PMC3908370
AbstractArticlePDF–513K
19.
ALOX5AP Variants are Associated with In-Stent Restenosis After Percutaneous Coronary Intervention
Svati H. Shah, Elizabeth R. Hauser, David Crosslin, Liyong Wang, Carol Haynes, Jessica Connelly, Sarah Nelson, Jessica Johnson, Shera Gadson, Charlotte L. Nelson, David Seo, Simon Gregory, William E. Kraus, Christopher B. Granger, Pascal Goldschmidt-Clermont, L. Kristin Newby
Atherosclerosis. Author manuscript; available in PMC 2013 Aug 5.
Published in final edited form as: Atherosclerosis. 2008 Nov; 201(1): 148–154. Published online 2008 Feb 12. doi: 10.1016/j.atherosclerosis.2008.01.011
PMCID:
PMC3733458
AbstractArticlePDF–452K
20.
Genetic Variation in the Lipoxygenase Pathway and Risk of Colorectal Neoplasia
Sarah E. Kleinstein, Laura Heath, Karen W. Makar, Elizabeth M. Poole, Brenna L. Seufert, Martha L. Slattery, Liren Xiao, David J. Duggan, Li Hsu, Karen Curtin, Lisel Koepl, Jill Muehling, Darin Taverna, Bette J. Caan, Christopher S. Carlson, John D. Potter, Cornelia M. Ulrich
Genes Chromosomes Cancer. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Genes Chromosomes Cancer. 2013 May; 52(5): 437–449. Published online 2013 Feb 12. doi: 10.1002/gcc.22042
PMCID:
PMC3698944
AbstractArticlePDF–335K

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