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Items: 1 to 20 of 46

1.
Favorable prognostic influence of T-box transcription factor Eomesodermin in metastatic renal cell cancer patients
Anastasia Dielmann, Anne Letsch, Anika Nonnenmacher, Kurt Miller, Ulrich Keilholz, Antonia Busse
Cancer Immunol Immunother. 2016 Feb; 65(2): 181–192. Published online 2016 Jan 11. doi: 10.1007/s00262-015-1786-1
PMCID:
PMC11029520
AbstractArticlePDF–1.2M
2.
Eomes-dependent mitochondrial regulation promotes survival of pathogenic CD4+ T cells during inflammation
Emeline Joulia, Michaël F. Michieletto, Arantxa Agesta, Cindy Peillex, Virginie Girault, Anne-Louise Le Dorze, Romain Peroceschi, Florence Bucciarelli, Marion Szelechowski, Adeline Chaubet, Nawad Hakim, Rémi Marrocco, Emeline Lhuillier, Manuel Lebeurrier, Rafael J. Argüello, Abdelhadi Saoudi, Hicham El Costa, Veronique Adoue, Thierry Walzer, Jean-Emmanuel Sarry, Anne S. Dejean
J Exp Med. 2024 Feb 5; 221(2): e20230449. Published online 2024 Jan 8. doi: 10.1084/jem.20230449
PMCID:
PMC10772920
AbstractArticlePDF–8.3M
3.
T-BET and EOMES sustain mature human NK cell identity and antitumor function
Pamela Wong, Jennifer A. Foltz, Lily Chang, Carly C. Neal, Tony Yao, Celia C. Cubitt, Jennifer Tran, Samantha Kersting-Schadek, Sathvik Palakurty, Natalia Jaeger, David A. Russler-Germain, Nancy D. Marin, Margery Gang, Julia A. Wagner, Alice Y. Zhou, Miriam T. Jacobs, Mark Foster, Timothy Schappe, Lynne Marsala, Ethan McClain, Patrick Pence, Michelle Becker-Hapak, Bryan Fisk, Allegra A. Petti, Obi L. Griffith, Malachi Griffith, Melissa M. Berrien-Elliott, Todd A. Fehniger
J Clin Invest. 2023 Jul 3; 133(13): e162530. Published online 2023 Jul 3. doi: 10.1172/JCI162530
PMCID:
PMC10313375
AbstractArticlePDF–13M
4.
Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition
Nils H. Wildner, Andreas Walker, Franziska Brauneck, Vanessa Ditt, Sven Peine, Samuel Huber, Friedrich Haag, Claudia Beisel, Joerg Timm, Julian Schulze zur Wiesch
Front Immunol. 2022; 13: 886646. Published online 2022 Jun 6. doi: 10.3389/fimmu.2022.886646
PMCID:
PMC9207347
AbstractArticlePDF–5.2M
5.
EOMES is essential for antitumor activity of CD8+ T cells in chronic lymphocytic leukemia
Laura Llaó-Cid, Philipp M. Roessner, Vicente Chapaprieta, Selcen Öztürk, Tobias Roider, Marie Bordas, Ana Izcue, Dolors Colomer, Sascha Dietrich, Stephan Stilgenbauer, Bola Hanna, José Ignacio Martín-Subero, Martina Seiffert
Leukemia. 2021; 35(11): 3152–3162. Published online 2021 Mar 17. doi: 10.1038/s41375-021-01198-1
PMCID:
PMC8550953
AbstractArticlePDF–2.1M
6.
T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells
Laura Kiekens, Wouter Van Loocke, Sylvie Taveirne, Sigrid Wahlen, Eva Persyn, Els Van Ammel, Zenzi De Vos, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq
Front Immunol. 2021; 12: 732511. Published online 2021 Sep 24. doi: 10.3389/fimmu.2021.732511
PMCID:
PMC8497824
AbstractArticlePDF–4.2M
7.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
AbstractArticlePDF–2.6M
8.
Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis
Ben J. E. Raveney, Wakiro Sato, Daiki Takewaki, Chenyang Zhang, Tomomi Kanazawa, Youwei Lin, Tomoko Okamoto, Manabu Araki, Yukio Kimura, Noriko Sato, Terunori Sano, Yuko Saito, Shinji Oki, Takashi Yamamura
Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2021818118. Published online 2021 Mar 8. doi: 10.1073/pnas.2021818118
PMCID:
PMC7980371
AbstractArticlePDF–1.9M
9.
Down‐regulation of EOMES drives T‐cell exhaustion via abolishing EOMES‐mediated repression of inhibitory receptors of T cells in liver cancer
Hongwei He, Yong Yi, Xiaoyan Cai, Jiaxing Wang, Xiaochun Ni, Yipeng Fu, Shuangjian Qiu
J Cell Mol Med. 2021 Jan; 25(1): 161–169. Published online 2020 Dec 16. doi: 10.1111/jcmm.15898
PMCID:
PMC7810931
AbstractArticlePDF–1.1M
10.
Eomes promotes esophageal carcinoma progression by recruiting Treg cells through the CCL20‐CCR6 pathway
Jingyao Lian, Saisai Liu, Ying Yue, Qingshan Yang, Zhen Zhang, Shengli Yang, Yi Zhang
Cancer Sci. 2021 Jan; 112(1): 144–154. Published online 2020 Nov 17. doi: 10.1111/cas.14712
PMCID:
PMC7780006
AbstractArticlePDF–1.5M
11.
HIV immune activation drives increased Eomes expression in memory CD8 T cells in association with transcriptional downregulation of CD127
Rebecca B. Hasley, Changwan Hong, Wenqing Li, Travis Friesen, Yoriko Nakamura, Grace Y. Kim, Jung-Hyun Park, Julie A. Hixon, Scott Durum, Zonghui Hu, Michael C. Sneller, Raphael Oguariri, Tomozumi Imamichi, H. Clifford Lane, Marta Catalfamo
AIDS. Author manuscript; available in PMC 2020 Oct 21.
Published in final edited form as: AIDS. 2013 Jul 31; 27(12): 1867–1877. doi: 10.1097/QAD.0b013e3283618487
PMCID:
PMC7577351
AbstractArticlePDF–1.8M
12.
Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch
Wen Juan Tu, Robert D. McCuaig, Abel H. Y. Tan, Kristine Hardy, Nabila Seddiki, Sayed Ali, Jane E. Dahlstrom, Elaine G. Bean, Jenny Dunn, Jade Forwood, Sofia Tsimbalyuk, Kate Smith, Desmond Yip, Laeeq Malik, Thiru Prasanna, Peter Milburn, Sudha Rao
Front Immunol. 2020; 11: 1228. Published online 2020 Jun 16. doi: 10.3389/fimmu.2020.01228
PMCID:
PMC7309504
AbstractArticlePDF–3.0M
13.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
14.
Intermediate progenitors and Tbr2 in cortical development
Robert F. Hevner
J Anat. 2019 Sep; 235(3): 616–625. Published online 2019 Jan 24. doi: 10.1111/joa.12939
PMCID:
PMC6656625
AbstractArticlePDF–424K
15.
Characterization of eomesodermin and T‐bet expression by allostimulated CD8+ T cells of healthy volunteers and kidney transplant patients in relation to graft outcome
A. Perez‐Gutierrez, D. M. Metes, L. Lu, S. Hariharan, A. W. Thomson, M. B. Ezzelarab
Clin Exp Immunol. 2018 Nov; 194(2): 259–272. Published online 2018 Sep 23. doi: 10.1111/cei.13162
PMCID:
PMC6194331
AbstractArticlePDF–1.2M
16.
Variant of EOMES Associated with Increasing Risk in Chinese Patients with Relapsing-remitting Multiple Sclerosis
Sheng Chen, Juan Zhang, Qi-Bing Liu, Jing-Cong Zhuang, Lei Wu, Yong-Feng Xu, Hong-Fu Li, Zhi-Ying Wu, Bao-Gou Xiao
Chin Med J (Engl) 2018 Mar 20; 131(6): 643–647. doi: 10.4103/0366-6999.226892
PMCID:
PMC5865308
AbstractArticlePDF–699K
17.
Cardiogenic programming of human pluripotent stem cells by dose-controlled activation of EOMES
Martin J. Pfeiffer, Roberto Quaranta, Ilaria Piccini, Jakob Fell, Jyoti Rao, Albrecht Röpke, Guiscard Seebohm, Boris Greber
Nat Commun. 2018; 9: 440. Published online 2018 Jan 30. doi: 10.1038/s41467-017-02812-6
PMCID:
PMC5789885
AbstractArticlePDF–1.5M
18.
Eomesodermin and T-bet mark developmentally distinct human natural killer cells
Amélie Collins, Nyanza Rothman, Kang Liu, Steven L. Reiner
JCI Insight. 2017 Mar 9; 2(5): e90063. Published online 2017 Mar 9. doi: 10.1172/jci.insight.90063
PMCID:
PMC5333970
AbstractArticlePDF–1.2M
19.
Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation
Antonia O. Cuff, Francis P. Robertson, Kerstin A. Stegmann, Laura J. Pallett, Mala K. Maini, Brian R. Davidson, Victoria Male
J Immunol. 2016 Dec 1; 197(11): 4283–4291. Published online 2016 Oct 21. doi: 10.4049/jimmunol.1601424
PMCID:
PMC5114885
AbstractArticlePDF–1.5M
20.
Variation at 3p24.1 and 6q23.3 influences the risk of Hodgkin’s Lymphoma
Matthew Frampton, Miguel Inacio da Silva Filho, Peter Broderick, Hauke Thomsen, Asta Försti, Jayaram Vijayakrishnan, Rosie Cooke, Victor Enciso-Mora, Per Hoffmann, Markus M Nöthen, Amy Lloyd, Amy Holroyd, Lewin Eisele, Karl-Heinz Jöckel, Sabine Ponader, Elke Pogge von Strandmann, Tracy Lightfoot, Eve Roman, Annette Lake, Dorothy Montgomery, Ruth F Jarrett, Anthony J Swerdlow, Andreas Engert, Kari Hemminki, Richard S Houlston
Nat Commun. Author manuscript; available in PMC 2016 Oct 6.
Published in final edited form as: Nat Commun. 2013; 4: 2549. doi: 10.1038/ncomms3549
PMCID:
PMC5053363
AbstractArticlePDF–1.4M

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