PMC Links for GEO Profiles (Select 119877889) - PMC

Marco Jessen, Dörthe Gertzmann, Franziska Liss, Franziska Zenk, Laura Bähner, Victoria Schöffler, Clemens Schulte, Hans Michael Maric, Carsten P. Ade, Björn von Eyss, Stefan Gaubatz

Oncogene. 2024; 43(8): 578–593. Published online 2024 Jan 5. doi: 10.1038/s41388-023-02926-w

PMCID:: PMC10873197

Abstract Article PDF–2.7M

Select item 108508184.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 100729065.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 91991376.

NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143

Wei Su, Hao Hu, Qiurong Ding, Min Wang, Yan Zhu, Zhaochao Zhang, Zihan Geng, Shengli Lin, Pinghong Zhou

Cell Commun Signal. 2022; 20: 87. Published online 2022 Jun 15. doi: 10.1186/s12964-022-00898-0

PMCID:: PMC9199137

Abstract Article PDF–4.0M

Select item 91197367.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 89486598.

Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma

Xiangling Feng, Jiaojiao Guo, Gang An, Yangbowen Wu, Zhenhao Liu, Bin Meng, Nihan He, Xinying Zhao, Shilian Chen, Yinghong Zhu, Jiliang Xia, Xin Li, Zhiyong Yu, Ruixuan Li, Guofeng Ren, Jihua Chen, Minghua Wu, Yanjuan He, Lugui Qiu, Jiaxi Zhou, Wen Zhou

Adv Sci (Weinh) 2022 Mar; 9(9): 2104491. Published online 2022 Jan 27. doi: 10.1002/advs.202104491

PMCID:: PMC8948659

Abstract Article PDF–6.5M

Select item 87603059.

NEK2 enhances malignancies of glioblastoma via NIK/NF-κB pathway

Jianyang Xiang, Wahafu Alafate, Wei Wu, Yichang Wang, Xiaodong Li, Wanfu Xie, Xiaobin Bai, Ruichun Li, Maode Wang, Jia Wang

Cell Death Dis. 2022 Jan; 13(1): 58. Published online 2022 Jan 14. doi: 10.1038/s41419-022-04512-6

PMCID:: PMC8760305

Abstract Article PDF–5.5M

Select item 872664410.

ETV4 mediated lncRNA C2CD4D-AS1 overexpression contributes to the malignant phenotype of lung adenocarcinoma cells via miR-3681-3p/NEK2 axis

Binliang Wang, Yuanyuan Cai, Xiaobo Li, Yiming Kong, Haiwei Fu, Jianying Zhou

Cell Cycle. 2021; 20(24): 2607–2618. Published online 2021 Dec 1. doi: 10.1080/15384101.2021.2005273

PMCID:: PMC8726644

Abstract Article PDF–3.6M

Select item 831646911.

NEK2 inhibition triggers anti-pancreatic cancer immunity by targeting PD-L1

Xiaozhen Zhang, Xing Huang, Jian Xu, Enliang Li, Mengyi Lao, Tianyu Tang, Gang Zhang, Chengxiang Guo, Xiaoyu Zhang, Wen Chen, Dipesh Kumar Yadav, Xueli Bai, Tingbo Liang

Nat Commun. 2021; 12: 4536. Published online 2021 Jul 27. doi: 10.1038/s41467-021-24769-3

PMCID:: PMC8316469

Abstract Article PDF–11M

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807971113.

The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells

Yainyrette Rivera-Rivera, Mihaela Marina, Shirley Jusino, Miyoung Lee, Jaleisha Vélez Velázquez, Camille Chardón-Colón, Geraldine Vargas, Jaya Padmanabhan, Srikumar P. Chellappan, Harold I. Saavedra

Sci Rep. 2021; 11: 9016. Published online 2021 Apr 27. doi: 10.1038/s41598-021-88512-0

PMCID:: PMC8079711

Abstract Article PDF–2.0M

Select item 798336614.

The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability

J Du, X Cai, J Yao, X Ding, Q Wu, S Pei, K Jiang, Y Zhang, W Wang, Y Shi, Y Lai, J Shen, M Teng, H Huang, Q Fei, ES Reddy, J Zhu, C Jin, X Yao

Oncogene. Author manuscript; available in PMC 2021 Mar 22.

Published in final edited form as: Oncogene. 2008 Jul 3; 27(29): 4107–4114. Published online 2008 Feb 25. doi: 10.1038/onc.2008.34

PMCID:: PMC7983366

Abstract Article PDF–1.3M

Select item 770944715.

Mutant p53 drives the loss of heterozygosity by the upregulation of Nek2 in breast cancer cells

Amr Ghaleb, Malik Padellan, Natalia Marchenko

Breast Cancer Res. 2020; 22: 133. Published online 2020 Dec 2. doi: 10.1186/s13058-020-01370-y

PMCID:: PMC7709447

Abstract Article PDF–2.4M

Select item 766637116.

TRIM27 Functions as a Novel Oncogene in Non-Triple-Negative Breast Cancer by Blocking Cellular Senescence through p21 Ubiquitination

Li Xing, Xiaolong Tang, Kaikai Wu, Xiong Huang, Yi Yi, Jinliang Huan

Mol Ther Nucleic Acids. 2020 Dec 4; 22: 910–923. Published online 2020 Oct 15. doi: 10.1016/j.omtn.2020.10.012

PMCID:: PMC7666371

Abstract Article PDF–4.6M

Select item 759045317.

Involvement of NEK2 and its interaction with NDC80 and CEP250 in hepatocellular carcinoma

Lu Zeng, Xiude Fan, Xiaoyun Wang, Huan Deng, Xiaoge Zhang, Kun Zhang, Shan He, Na Li, Qunying Han, Zhengwen Liu

BMC Med Genomics. 2020; 13: 158. Published online 2020 Oct 27. doi: 10.1186/s12920-020-00812-y

PMCID:: PMC7590453

Abstract Article PDF–2.0M

Select item 748804018.

Targeting NEK2 impairs oncogenesis and radioresistance via inhibiting the Wnt1/β-catenin signaling pathway in cervical cancer

Tie Xu, Yulan Zeng, Linli Shi, Qin Yang, Yeshan Chen, Gang Wu, Guiling Li, Shuangbing Xu

J Exp Clin Cancer Res. 2020; 39: 183. Published online 2020 Sep 10. doi: 10.1186/s13046-020-01659-y

PMCID:: PMC7488040

Abstract Article PDF–5.6M

Select item 740226619.

APC/C-dependent control of gene expression and cell identity

Eugene Oh, Kevin G. Mark, Annamaria Mocciaro, Edmond R. Watson, J. Rajan Prabu, Denny D. Cha, Martin Kampmann, Nathan Gamarra, Coral Y. Zhou, Michael Rape

Nature. Author manuscript; available in PMC 2020 Aug 19.

Published in final edited form as: Nature. 2020 Mar; 579(7797): 136–140. Published online 2020 Feb 19. doi: 10.1038/s41586-020-2034-1

PMCID:: PMC7402266

Abstract Article PDF–5.3M

Select item 739591620.

High Expression of NEK2 and PIM1, but Not PIM3, Is Linked to an Aggressive Phenotype of Bronchopulmonary Neuroendocrine Neoplasms

Ewelina Motylewska, Marcin Braun, Henryk Stępień

Endocr Pathol. 2020; 31(3): 264–273. Published online 2020 Jun 5. doi: 10.1007/s12022-020-09629-y

PMCID:: PMC7395916

Abstract Article PDF–5.1M

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