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Select item 113030701.

Methyl-CpG-binding 2 K271 lactylation-mediated M2 macrophage polarization inhibits atherosclerosis

Liangqi Chen, Meiju Zhang, Xueyan Yang, Yanan Wang, Tuo Huang, Xin Li, Yunting Ban, Qifeng Li, Qingyuan Yang, Yongxiang Zhang, Yang Zheng, Di Wang, Xiaoqi Wang, Xiujie Shi, Maomao Zhang, Yong Sun, Jian Wu

Theranostics. 2024; 14(11): 4256–4277. Published online 2024 Jul 8. doi: 10.7150/thno.94738

PMCID:: PMC11303070

Abstract Article PDF–12M

Select item 111134362.

Chromatin composition alterations and the critical role of MeCP2 for epigenetic silencing of progesterone receptor-B gene in endometrial cancers

Yongli Chu, Yanlin Wang, Guanghua Zhang, Haibin Chen, Sean C. Dowdy, Yuning Xiong, Fengming Liu, Run Zhang, Jinping Li, Shi-Wen Jiang

Cell Mol Life Sci. 2014 Sep; 71(17): 3393–3408. Published online 2014 Feb 15. doi: 10.1007/s00018-014-1580-9

PMCID:: PMC11113436

Abstract Article PDF–1.8M

Select item 109975543.

CRL4^DCAF13 E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes

Peipei Ren, Xiaomei Tong, Junjian Li, Huifang Jiang, Siya Liu, Xiang Li, Mengru Lai, Weijie Yang, Yan Rong, Yingyi Zhang, Jiamin Jin, Yerong Ma, Weiwei Pan, Heng-Yu Fan, Songying Zhang, Yin-Li Zhang

Cell Mol Life Sci. 2024 Dec; 81(1): 165. Published online 2024 Apr 5. doi: 10.1007/s00018-024-05185-4

PMCID:: PMC10997554

Abstract Article PDF–8.5M

Select item 108757454.

Genetic analysis of a pedigree with MECP2 duplication syndrome in China

Lan Zeng, Hui Zhu, Jin Wang, Qiyan Wang, Ying Pang, Zemin Luo, Ai Chen, Shengfang Qin, Shuyao Zhu

BMC Med Genomics. 2024; 17: 54. Published online 2024 Feb 19. doi: 10.1186/s12920-024-01831-9

PMCID:: PMC10875745

Abstract Article PDF–2.4M

Select item 108577745.

Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation

Jialin Sun, Sivan Osenberg, Austin Irwin, Li-Hua Ma, Nigel Lee, Yangfei Xiang, Feng Li, Ying-Wooi Wan, In-Hyun Park, Mirjana Maletic-Savatic, Nurit Ballas

Cell Rep. Author manuscript; available in PMC 2024 Feb 9.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 111942. Published online 2023 Jan 5. doi: 10.1016/j.celrep.2022.111942

PMCID:: PMC10857774

Abstract Article PDF–4.3M

Select item 107695556.

Analysis of the interplay between MeCP2 and histone H1 during in vitro differentiation of human ReNCell neural progenitor cells

Edilene Siqueira, Bo-Hyun Kim, Larry Reser, Robert Chow, Kerry Delaney, Manel Esteller, Mark M. Ross, Jeffrey Shabanowitz, Donald F. Hunt, Sonia Guil, Juan Ausió

Epigenetics. 2023; 18(1): 2276425. Published online 2023 Nov 17. doi: 10.1080/15592294.2023.2276425

PMCID:: PMC10769555

Abstract Article PDF–7.1M

Select item 107649587.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 105658768.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 105240279.

Exploring Gastrointestinal Health in MECP2 Duplication Syndrome

Davut Pehlivan, Muharrem Ak, Daniel G. Glaze, Bernhard Suter, Kathleen J. Motil

Neurogastroenterol Motil. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Neurogastroenterol Motil. 2023 Aug; 35(8): e14601. Published online 2023 Apr 30. doi: 10.1111/nmo.14601

PMCID:: PMC10524027

Abstract Article PDF–897K

Select item 1032903510.

Methyl-CpG binding protein 2 expression is associated with symptom severity in patients with PTSD in a sex-dependent manner

Livia Cosentino, Stephanie H. Witt, Helene Dukal, Francesca Zidda, Sebastian Siehl, Herta Flor, Bianca De Filippis

Transl Psychiatry. 2023; 13: 249. Published online 2023 Jul 7. doi: 10.1038/s41398-023-02529-9

PMCID:: PMC10329035

Abstract Article PDF–840K

Select item 1023742211.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1012009112.

MECP2 germline mosaicism plays an important part in the inheritance of Rett syndrome: a study of MECP2 germline mosaicism in males

Yongxin Wen, Jiaping Wang, Qingping Zhang, Xiaoxu Yang, Liping Wei, Xinhua Bao

BMC Med. 2023; 21: 155. Published online 2023 Apr 20. doi: 10.1186/s12916-023-02846-2

PMCID:: PMC10120091

Abstract Article PDF–2.1M

Select item 1006659613.

DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops

Esther Marchena-Cruz, Lola P. Camino, Jay Bhandari, Sónia Silva, José Javier Marqueta-Gracia, Shahad A. Amdeen, Cristina Guillén-Mendoza, María L. García-Rubio, José M. Calderón-Montaño, Xiaoyu Xue, Rosa Luna, Andrés Aguilera

Cell Rep. 2023 Mar 28; 42(3): 112148. Published online 2023 Feb 23. doi: 10.1016/j.celrep.2023.112148

PMCID:: PMC10066596

Abstract Article

Select item 999549614.

A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay

Beatrice Alexander-Howden, Li Zhang, Almer M. van der Sloot, Sylvain Tollis, Daniel J. St-Cyr, Frank Sicheri, Adrian P. Bird, Mike Tyers, Matthew J. Lyst

Sci Rep. 2023; 13: 3868. Published online 2023 Mar 8. doi: 10.1038/s41598-023-29915-z

PMCID:: PMC9995496

Abstract Article PDF–2.4M

Select item 997112915.

MiR-422a promotes adipogenesis via MeCP2 downregulation in human bone marrow mesenchymal stem cells

Angelica Giuliani, Jacopo Sabbatinelli, Stefano Amatori, Laura Graciotti, Andrea Silvestrini, Giulia Matacchione, Deborah Ramini, Emanuela Mensà, Francesco Prattichizzo, Lucia Babini, Domenico Mattiucci, Elena Marinelli Busilacchi, Maria Giulia Bacalini, Emma Espinosa, Fabrizia Lattanzio, Antonio Domenico Procopio, Fabiola Olivieri, Antonella Poloni, Mirco Fanelli, Maria Rita Rippo

Cell Mol Life Sci. 2023 Mar; 80(3): 75. Published online 2023 Feb 27. doi: 10.1007/s00018-023-04719-6

PMCID:: PMC9971129

Abstract Article PDF–2.3M

Select item 995044716.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 987198317.

Impact of Rett Syndrome Mutations on MeCP2 MBD Stability

Tugba G Kucukkal, Ye Yang, Olga Uvarov, Weiguo Cao, Emil Alexov

Biochemistry. Author manuscript; available in PMC 2023 Jan 24.

Published in final edited form as: Biochemistry. 2015 Oct 20; 54(41): 6357–6368. Published online 2015 Oct 8. doi: 10.1021/acs.biochem.5b00790

PMCID:: PMC9871983

Abstract Article PDF–2.6M

Select item 977929418.

The Chromatin Structure at the MECP2 Gene and In Silico Prediction of Potential Coding and Non-Coding MECP2 Splice Variants

Danilo Shevkoplyas, Yen My Vuu, James R. Davie, Mojgan Rastegar

Int J Mol Sci. 2022 Dec; 23(24): 15643. Published online 2022 Dec 9. doi: 10.3390/ijms232415643

PMCID:: PMC9779294

Abstract Article PDF–6.9M

Select item 977255819.

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation

Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang

Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005

PMCID:: PMC9772558

Abstract Article PDF–8.2M

Select item 970808620.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

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PMC Links for GEO Profiles (Select 117439367) (354)
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dbVar for Gene (Select 8277) (454)
dbVar
histone-arginine methyltransferase METTL23 isoform X1 [Gymnogyps californianus]
histone-arginine methyltransferase METTL23 isoform X1 [Gymnogyps californianus]
gi|2312042238|ref|XP_050764268.1|

Protein
Roseburia intestinalis L1-82, whole genome shotgun sequencing project
Roseburia intestinalis L1-82, whole genome shotgun sequencing project
gi|239923919|gb|ABYJ00000000.2|ABYJ 000

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