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Items: 1 to 20 of 40

1.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4
PMCID:
PMC10869800
AbstractArticlePDF–9.3M
2.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
3.
Cytoplasmic YAP1‐mediated ESCRT‐III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer
Yan Guo, Yuqing Cui, Yangyang Li, Xiaoying Jin, Dandan Wang, Mengxia Lei, Fengzhi Chen, Yali Liu, Jinwen Xu, Guanyu Yao, Guangchun Zeng, Xuesong Chen
Cancer Commun (Lond) 2023 May; 43(5): 582–612. Published online 2023 Apr 2. doi: 10.1002/cac2.12417
PMCID:
PMC10174091
AbstractArticlePDF–22M
4.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
5.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
6.
TRIM24 is an insulin-responsive regulator of P-bodies
Wen Wei, Qiaoli Chen, Minjun Liu, Yang Sheng, Qian OuYang, Weikuan Feng, Xinyu Yang, Longfei Ding, Shu Su, Jingzi Zhang, Lei Fang, Antonio Vidal-Puig, Hong-Yu Wang, Shuai Chen
Nat Commun. 2022; 13: 3972. Published online 2022 Jul 8. doi: 10.1038/s41467-022-31735-0
PMCID:
PMC9270398
AbstractArticlePDF–5.2M
7.
Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors
Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen
Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638
PMCID:
PMC9106303
AbstractArticlePDF–918K
8.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
9.
ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation
Yana van der Weegen, Klaas de Lint, Diana van den Heuvel, Yuka Nakazawa, Tycho E.T. Mevissen, Janne J.M. van Schie, Marta San Martin Alonso, Daphne E.C. Boer, Román González-Prieto, Ishwarya V. Narayanan, Noud H.M. Klaassen, Annelotte P. Wondergem, Khashayar Roohollahi, Josephine C. Dorsman, Yuichiro Hara, Alfred C.O. Vertegaal, Job de Lange, Johannes C. Walter, Sylvie M. Noordermeer, Mats Ljungman, Tomoo Ogi, Rob M.F. Wolthuis, Martijn S. Luijsterburg
Nat Cell Biol. Author manuscript; available in PMC 2022 Jun 9.
Published in final edited form as: Nat Cell Biol. 2021 Jun; 23(6): 595–607. Published online 2021 Jun 9. doi: 10.1038/s41556-021-00688-9
PMCID:
PMC8890769
AbstractArticlePDF–7.4M
10.
Aberrant expression of MYD88 via RNA‐controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer
Masumi Tsuda, Misa Noguchi, Tsuyoshi Kurai, Yuji Ichihashi, Koki Ise, Lei Wang, Yusuke Ishida, Mishie Tanino, Satoshi Hirano, Masahiro Asaka, Shinya Tanaka
Cancer Sci. 2021 Dec; 112(12): 5100–5113. Published online 2021 Oct 25. doi: 10.1111/cas.15157
PMCID:
PMC8645755
AbstractArticlePDF–1.6M
11.
Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins
Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer
Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490
PMCID:
PMC8266617
AbstractArticlePDF–4.0M
12.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
13.
Global proteomics of Ubqln2-based murine models of ALS
Alexandra M. Whiteley, Miguel A. Prado, Stefanie A.H. de Poot, Joao A. Paulo, Marissa Ashton, Sara Dominguez, Martin Weber, Hai Ngu, John Szpyt, Mark P. Jedrychowski, Amy Easton, Steven P. Gygi, Thimo Kurz, Mervyn J. Monteiro, Eric J. Brown, Daniel Finley
J Biol Chem. 2021 Jan-Jun; 296: 100153. Published online 2020 Dec 10. doi: 10.1074/jbc.RA120.015960
PMCID:
PMC7873701
AbstractArticlePDF–3.0M
14.
The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma
Francesca Beretti, Francesca Farnetani, Luca Reggiani Bonetti, Luca Fabbiani, Manuela Zavatti, Antonino Maiorana, Giovanni Pellacani, Tullia Maraldi
Int J Mol Sci. 2021 Jan; 22(2): 761. Published online 2021 Jan 13. doi: 10.3390/ijms22020761
PMCID:
PMC7828605
AbstractArticlePDF–4.1M
15.
CNOT4 enhances the efficacy of anti‐PD‐1 immunotherapy in a model of non‐small cell lung cancer
Biao Zhang, Song Han, Haitao Ma, Shaomu Chen
FEBS Open Bio. 2020 Dec; 10(12): 2631–2639. Published online 2020 Nov 5. doi: 10.1002/2211-5463.12998
PMCID:
PMC7714061
AbstractArticlePDF–1.9M
16.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
17.
Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation
Tobias Raisch, Chung-Te Chang, Yevgen Levdansky, Sowndarya Muthukumar, Stefan Raunser, Eugene Valkov
Nat Commun. 2019; 10: 3173. Published online 2019 Jul 18. doi: 10.1038/s41467-019-11094-z
PMCID:
PMC6639331
AbstractArticlePDF–3.8M
18.
The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer
Weimei Tang, Weijie Zhou, Li Xiang, Xiaosheng Wu, Pei Zhang, Jing Wang, Guangnan Liu, Wenjing Zhang, Ying Peng, Xiaoting Huang, Jianqun Cai, Yang Bai, Lan Bai, Wei Zhu, Hongxiang Gu, Jing Xiong, Chen Ye, Aimin Li, Side Liu, Jide Wang
Nat Commun. 2019; 10: 663. Published online 2019 Feb 8. doi: 10.1038/s41467-018-08225-3
PMCID:
PMC6368584
AbstractArticlePDF–6.8M
19.
A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex
Csilla Keskeny, Tobias Raisch, Annamaria Sgromo, Cátia Igreja, Dipankar Bhandari, Oliver Weichenrieder, Elisa Izaurralde
Genes Dev. 2019 Feb 1; 33(3-4): 236–252. doi: 10.1101/gad.320952.118
PMCID:
PMC6362812
AbstractArticlePDF–2.5M
20.
Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
Zhihao Wu, Yan Wang, Junghyun Lim, Boxiang Liu, Yanping Li, Rasika Vartak, Trisha Stankiewicz, Stephen Montgomery, Bingwei Lu
Cell Metab. Author manuscript; available in PMC 2019 Jul 3.
Published in final edited form as: Cell Metab. 2018 Jul 3; 28(1): 130–144.e7. Published online 2018 May 31. doi: 10.1016/j.cmet.2018.05.007
PMCID:
PMC5989559
AbstractArticlePDF–1.6M

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