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Select item 108745811.

HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1

Hang You, Guojing Song, Zhizhen Xu, Saipeng Chen, Wenhao Shen, Heting Liu, Bingqian Deng, Jun Li, Gang Huang

J Transl Med. 2024; 22: 178. Published online 2024 Feb 18. doi: 10.1186/s12967-024-04970-w

PMCID:: PMC10874581

Abstract Article PDF–7.9M

Select item 94819332.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 92566853.

BCAT1 promotes osteoclast maturation by regulating branched-chain amino acid metabolism

Miyeon Go, Eunji Shin, Seo Young Jang, Miso Nam, Geum-Sook Hwang, Soo Young Lee

Exp Mol Med. 2022 Jun; 54(6): 825–833. Published online 2022 Jun 27. doi: 10.1038/s12276-022-00775-3

PMCID:: PMC9256685

Abstract Article PDF–2.7M

Select item 91026344.

Impaired expression of BCAT1 relates to muscle atrophy of mouse model of sarcopenia

Hui Ouyang, Xuguang Gao, Jun Zhang

BMC Musculoskelet Disord. 2022; 23: 450. Published online 2022 May 13. doi: 10.1186/s12891-022-05332-7

PMCID:: PMC9102634

Abstract Article PDF–1.2M

Select item 87442575.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Abstract Article PDF–6.0M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 74948547.

BCAT1 binds the RNA-binding protein ZNF423 to activate autophagy via the IRE1-XBP-1-RIDD axis in hypoxic PASMCs

Wei Xin, Min Zhang, Yang Yu, Songlin Li, Cui Ma, Junting Zhang, Yuan Jiang, Yiying Li, Xiaodong Zheng, Lixin Zhang, Xijuan Zhao, Xuzhong Pei, Daling Zhu

Cell Death Dis. 2020 Sep; 11(9): 764. Published online 2020 Sep 16. doi: 10.1038/s41419-020-02930-y

Correction in:: Cell Death Dis. 2022 Jan; 13(1): 27.

PMCID:: PMC7494854

Abstract Article PDF–3.5M

Select item 73514918.

A trans-eQTL network regulates osteoclast multinucleation and bone mass

Marie Pereira, Jeong-Hun Ko, John Logan, Hayley Protheroe, Kee-Beom Kim, Amelia Li Min Tan, Peter I Croucher, Kwon-Sik Park, Maxime Rotival, Enrico Petretto, JH Duncan Bassett, Graham R Williams, Jacques Behmoaras

eLife. 2020; 9: e55549. Published online 2020 Jun 19. doi: 10.7554/eLife.55549

PMCID:: PMC7351491

Abstract Article PDF–5.1M

Select item 62037669.

Mice deficient in the mitochondrial branched-chain aminotransferase (BCATm) respond with delayed tumour growth to a challenge with EL-4 lymphoma

Elitsa A. Ananieva, Joshua N. Bostic, Ashley A. Torres, Hannah R. Glanz, Sean M. McNitt, Michelle K. Brenner, Michael P. Boyer, Adele K. Addington, Susan M. Hutson

Br J Cancer. 2018 Oct 16; 119(8): 1009–1017. Published online 2018 Oct 15. doi: 10.1038/s41416-018-0283-7

PMCID:: PMC6203766

Abstract Article PDF–948K

Select item 586277110.

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies

David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury

Nat Genet. Author manuscript; available in PMC 2018 Aug 19.

Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7

PMCID:: PMC5862771

Abstract Article PDF–2.5M

Select item 551022911.

BCAT1 controls metabolic reprogramming in activated human macrophages and is associated with inflammatory diseases

Adonia E. Papathanassiu, Jeong-Hun Ko, Martha Imprialou, Marta Bagnati, Prashant K. Srivastava, Hong A. Vu, Danilo Cucchi, Stephen P. McAdoo, Elitsa A. Ananieva, Claudio Mauro, Jacques Behmoaras

Nat Commun. 2017; 8: 16040. Published online 2017 Jul 12. doi: 10.1038/ncomms16040

PMCID:: PMC5510229

Abstract Article PDF–1.8M

Select item 478346912.

Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse

Chao Yu, Shu-Yan Ji, Yu-Jiao Dang, Qian-Qian Sha, Yi-Feng Yuan, Jian-Jie Zhou, Li-Ying Yan, Jie Qiao, Fuchou Tang, Heng-Yu Fan

Cell Res. 2016 Mar; 26(3): 275–287. Published online 2016 Feb 23. doi: 10.1038/cr.2016.20

PMCID:: PMC4783469

Abstract Article PDF–9.2M

Select item 462900413.

Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover

Christopher J. Lynch, Scot R. Kimball, Yuping Xu, Anna C. Salzberg, Yuka Imamura Kawasawa

Physiol Genomics. 2015 Nov; 47(11): 569–580. Published online 2015 Sep 8. doi: 10.1152/physiolgenomics.00055.2015

PMCID:: PMC4629004

Abstract Article

Select item 431955914.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 408192215.

Cytosolic Branched Chain Aminotransferase (BCATc) Regulates mTORC1 Signaling and Glycolytic Metabolism in CD4⁺ T Cells

Elitsa A. Ananieva, Chirag H. Patel, Charles H. Drake, Jonathan D. Powell, Susan M. Hutson

J Biol Chem. 2014 Jul 4; 289(27): 18793–18804. Published online 2014 May 20. doi: 10.1074/jbc.M114.554113

PMCID:: PMC4081922

Abstract Article PDF–1.2M

Select item 386277616.

Oral Leucine Supplementation Is Sensed by the Brain but neither Reduces Food Intake nor Induces an Anorectic Pattern of Gene Expression in the Hypothalamus

Thais T. Zampieri, João A. B. Pedroso, Isadora C. Furigo, Julio Tirapegui, Jose Donato, Jr.

PLoS One. 2013; 8(12): e84094. Published online 2013 Dec 13. doi: 10.1371/journal.pone.0084094

PMCID:: PMC3862776

Abstract Article PDF–1.5M

Select item 381794617.

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates

Jeremy A. Miller, Jason Nathanson, Daniel Franjic, Sungbo Shim, Rachel A. Dalley, Sheila Shapouri, Kimberly A. Smith, Susan M. Sunkin, Amy Bernard, Jeffrey L. Bennett, Chang-Kyu Lee, Michael J. Hawrylycz, Allan R. Jones, David G. Amaral, Nenad Sestan, Fred H. Gage, Ed S. Lein

Development. 2013 Nov 15; 140(22): 4633–4644. doi: 10.1242/dev.097212

PMCID:: PMC3817946

Abstract Article

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253419.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 296247020.

Transamination Is Required for α-Ketoisocaproate but Not Leucine to Stimulate Insulin Secretion

Yingsheng Zhou, Thomas L. Jetton, Stephanie Goshorn, Christopher J. Lynch, Pengxiang She

J Biol Chem. 2010 Oct 29; 285(44): 33718–33726. Published online 2010 Aug 24. doi: 10.1074/jbc.M110.136846

PMCID:: PMC2962470

Abstract Article PDF–2.3M

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