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Select item 110041801.

Decoding spatiotemporal transcriptional dynamics and epithelial fibroblast crosstalk during gastroesophageal junction development through single cell analysis

Naveen Kumar, Pon Ganish Prakash, Christian Wentland, Shilpa Mary Kurian, Gaurav Jethva, Volker Brinkmann, Hans-Joachim Mollenkopf, Tobias Krammer, Christophe Toussaint, Antoine-Emmanuel Saliba, Matthias Biebl, Christian Jürgensen, Bertram Wiedenmann, Thomas F. Meyer, Rajendra Kumar Gurumurthy, Cindrilla Chumduri

Nat Commun. 2024; 15: 3064. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47173-z

PMCID:: PMC11004180

Abstract Article PDF–23M

Select item 96818872.

SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation

Lingjie Yan, Tao Zhang, Kai Wang, Zezhao Chen, Yuanxin Yang, Bing Shan, Qi Sun, Mengmeng Zhang, Yichi Zhang, Yedan Zhong, Nan Liu, Jinyang Gu, Daichao Xu

Nat Commun. 2022; 13: 7153. Published online 2022 Nov 22. doi: 10.1038/s41467-022-34993-0

PMCID:: PMC9681887

Abstract Article PDF–8.5M

Select item 91832363.

Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria

Kuan Zhang, Erica Yao, Biao Chen, Ethan Chuang, Julia Wong, Robert I Seed, Stephen L Nishimura, Paul J Wolters, Pao-Tien Chuang

eLife. 2022; 11: e68598. Published online 2022 Apr 6. doi: 10.7554/eLife.68598

PMCID:: PMC9183236

Abstract Article PDF–33M

Select item 90208254.

Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse

Alexandre Grimaldi, Glenda Comai, Sebastien Mella, Shahragim Tajbakhsh

eLife. 2022; 11: e70235. Published online 2022 Feb 28. doi: 10.7554/eLife.70235

PMCID:: PMC9020825

Abstract Article PDF–18M

Select item 83200175.

The genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus

Jarod A. Zepp, Michael P. Morley, Claudia Loebel, Madison M. Kremp, Fatima N. Chaudhry, Maria C. Basil, John P. Leach, Derek C. Liberti, Terren K. Niethamer, Yun Ying, Sowmya Jayachandran, Apoorva Babu, Su Zhou, David B. Frank, Jason A. Burdick, Edward E. Morrisey

Science. Author manuscript; available in PMC 2021 Sep 12.

Published in final edited form as: Science. 2021 Mar 12; 371(6534): eabc3172. doi: 10.1126/science.abc3172

PMCID:: PMC8320017

Abstract Article PDF–5.9M

Select item 76696256.

Development and patterning of rib primordia are dependent on associated musculature

William M. Wood, Chelsea Otis, Shervin Etemad, David J. Goldhamer

Dev Biol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Dev Biol. 2020 Dec 1; 468(1-2): 133–145. Published online 2020 Aug 5. doi: 10.1016/j.ydbio.2020.07.015

PMCID:: PMC7669625

Abstract Article PDF–3.2M

Select item 76539117.

Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha

Julie L. Kadrmas, Mary C. Beckerle, Masaaki Yoshigi

Sci Rep. 2020; 10: 19303. Published online 2020 Nov 9. doi: 10.1038/s41598-020-75774-3

PMCID:: PMC7653911

Abstract Article PDF–5.2M

Select item 75611998.

Fgf10-CRISPR mosaic mutants demonstrate the gene dose-related loss of the accessory lobe and decrease in the number of alveolar type 2 epithelial cells in mouse lung

Munenori Habuta, Akihiro Yasue, Ken-ichi T. Suzuki, Hirofumi Fujita, Keita Sato, Hitomi Kono, Ayuko Takayama, Tetsuya Bando, Satoru Miyaishi, Seiichi Oyadomari, Eiji Tanaka, Hideyo Ohuchi

PLoS One. 2020; 15(10): e0240333. Published online 2020 Oct 15. doi: 10.1371/journal.pone.0240333

PMCID:: PMC7561199

Abstract Article PDF–4.6M

Select item 73191049.

GORAB promotes embryonic lung maturation through antagonizing AKT phosphorylation, versican expression and mesenchymal cell migration

Ying Liu, Xi Chen, Yeon Ja Choi, Ning Yang, Zhongya Song, Elizabeth R. Snedecor, Wei Liang, Elaine Lai-Han Leung, Lianfeng Zhang, Chuan Qin, Jiang Chen

FASEB J. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: FASEB J. 2020 Apr; 34(4): 4918–4933. Published online 2020 Feb 18. doi: 10.1096/fj.201902075R

PMCID:: PMC7319104

Abstract Article PDF–1.7M

Select item 729738510.

GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation

Anbarasi Kothandapani, Samantha R. Lewis, Jessica L. Noel, Abbey Zacharski, Kyle Krellwitz, Anna Baines, Stephanie Winske, Chad M. Vezina, Elena M. Kaftanovskaya, Alexander I. Agoulnik, Emily M. Merton, Martin J. Cohn, Joan S. Jorgensen

PLoS Genet. 2020 Jun; 16(6): e1008810. Published online 2020 Jun 4. doi: 10.1371/journal.pgen.1008810

PMCID:: PMC7297385

Abstract Article PDF–4.0M

Select item 721770211.

A mammalian Wnt5a–Ror2–Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis

Kuan Zhang, Erica Yao, Chuwen Lin, Yu-Ting Chou, Julia Wong, Jianying Li, Paul J Wolters, Pao-Tien Chuang

eLife. 2020; 9: e53688. Published online 2020 May 12. doi: 10.7554/eLife.53688

PMCID:: PMC7217702

Abstract Article PDF–8.0M

Select item 721306112.

Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis

Anna Heinrich, Sarah J. Potter, Li Guo, Nancy Ratner, Tony DeFalco

Cell Rep. Author manuscript; available in PMC 2020 May 11.

Published in final edited form as: Cell Rep. 2020 Apr 14; 31(2): 107513. doi: 10.1016/j.celrep.2020.03.077

PMCID:: PMC7213061

Abstract Article PDF–4.4M

Select item 719148013.

Lung developmental arrest caused by PDGF-A deletion: consequences for the adult mouse lung

Leonor Gouveia, Simone Kraut, Stefan Hadzic, Elisa Vazquéz-Liébanas, Baktybek Kojonazarov, Cheng-Yu Wu, Christine Veith, Liqun He, Georgios Mermelekas, Ralph Theo Schermuly, Norbert Weissmann, Christer Betsholtz, Johanna Andrae

Am J Physiol Lung Cell Mol Physiol. 2020 Apr 1; 318(4): L831–L843. Published online 2020 Mar 18. doi: 10.1152/ajplung.00295.2019

PMCID:: PMC7191480

Abstract Article

Select item 716090714.

CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis

Yen-Ting Lai, Hsu-Wen Chao, Alan Chuan-Ying Lai, Shu-Hui Lin, Ya-Jen Chang, Yi-Shuian Huang

J Biomed Sci. 2020; 27: 52. Published online 2020 Apr 15. doi: 10.1186/s12929-020-00643-0

PMCID:: PMC7160907

Abstract Article PDF–5.9M

Select item 670371015.

Secondary crest myofibroblast PDGFRα controls the elastogenesis pathway via a secondary tier of signaling networks during alveologenesis

Changgong Li, Matt K. Lee, Feng Gao, Sha Webster, Helen Di, Jiang Duan, Chang-Yo Yang, Navin Bhopal, Neil Peinado, Gloria Pryhuber, Susan M. Smith, Zea Borok, Saverio Bellusci, Parviz Minoo

Development. 2019 Aug 1; 146(15): dev176354. Published online 2019 Aug 9. doi: 10.1242/dev.176354