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Select item 108745811.

HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT1

Hang You, Guojing Song, Zhizhen Xu, Saipeng Chen, Wenhao Shen, Heting Liu, Bingqian Deng, Jun Li, Gang Huang

J Transl Med. 2024; 22: 178. Published online 2024 Feb 18. doi: 10.1186/s12967-024-04970-w

PMCID:: PMC10874581

Abstract Article PDF–7.9M

Select item 104354232.

ERK5 Cooperates With MEF2C to Regulate Nr4a1 Transcription in MA-10 and MLTC-1 Leydig Cells

Karine de Mattos, Félix-Olivier Dumas, Gabriel Henrique Campolina-Silva, Clémence Belleannée, Robert S Viger, Jacques J Tremblay

Endocrinology. 2023 Sep; 164(9): bqad120. Published online 2023 Aug 4. doi: 10.1210/endocr/bqad120

PMCID:: PMC10435423

Abstract Article

Select item 103179743.

Etiopathogenic role of ERK5 signaling in sarcoma: prognostic and therapeutic implications

Adrián Sánchez-Fdez, Sofía Matilla-Almazán, Sofía Del Carmen, Mar Abad, Elena Arconada-Luque, Jaime Jiménez-Suárez, Luis Miguel Chinchilla-Tábora, Mª José Ruíz-Hidalgo, Ricardo Sánchez-Prieto, Atanasio Pandiella, Azucena Esparís-Ogando

Exp Mol Med. 2023 Jun; 55(6): 1247–1257. Published online 2023 Jun 19. doi: 10.1038/s12276-023-01008-x

PMCID:: PMC10317974

Abstract Article PDF–3.8M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516155.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 100729066.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 100476877.

VEGF Stimulates Activation of ERK5 in the Absence of C-Terminal Phosphorylation Preventing Nuclear Localization and Facilitating AKT Activation in Endothelial Cells

Anil Kumar Mondru, Mohammad A. Aljasir, Ahmed Alrumayh, Gopika N. Nithianandarajah, Katie Ahmed, Jurgen Muller, Christopher E. P. Goldring, Bettina Wilm, Michael J. Cross

Cells. 2023 Mar; 12(6): 967. Published online 2023 Mar 22. doi: 10.3390/cells12060967

PMCID:: PMC10047687

Abstract Article PDF–4.5M

Select item 100354538.

MEK5-ERK5 Axis Promotes Self-renewal and Tumorigenicity of Glioma Stem Cells

Kazuya Fukasawa, Jiajun Lyu, Takuya Kubo, Yuki Tanaka, Akane Suzuki, Tetsuhiro Horie, Akane Tomizawa, Ryoma Osumi, Sayuki Iwahashi, Kazuya Tokumura, Misato Murata, Masaki Kobayashi, Tomoki Todo, Atsushi Hirao, Eiichi Hinoi

Cancer Res Commun. 2023 Jan; 3(1): 148–159. Published online 2023 Jan 30. doi: 10.1158/2767-9764.CRC-22-0243

PMCID:: PMC10035453

Abstract Article PDF–14M

Select item 100266339.

The Investigation of MAPK7 Gene Variations in Colorectal Cancer Risk

CANAN CACINA, ELIF ULU, SOYKAN ARIKAN, SAIME TURAN SURMEN, ILHAN YAYLIM

In Vivo. 2023 Mar-Apr; 37(2): 644–648. Published online 2023 Mar 3. doi: 10.21873/invivo.13123

PMCID:: PMC10026633

Abstract Article PDF–561K

Select item 984535710.

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity

Francesca Ippolito, Veronica Consalvi, Valeria Noce, Cecilia Battistelli, Carla Cicchini, Marco Tripodi, Laura Amicone, Alessandra Marchetti

Cell Death Dis. 2023 Jan; 14(1): 32. Published online 2023 Jan 17. doi: 10.1038/s41419-023-05569-7

PMCID:: PMC9845357

Abstract Article PDF–2.3M

Select item 952758311.

Overexpression of TRAF4 promotes lung cancer growth and EGFR‐dependent phosphorylation of ERK5

Siwei He, Danfeng Dong, Jiafei Lin, Beiying Wu, Xiaomeng Nie, Gang Cai

FEBS Open Bio. 2022 Oct; 12(10): 1747–1760. Published online 2022 Aug 17. doi: 10.1002/2211-5463.13458

PMCID:: PMC9527583

Abstract Article PDF–8.4M

Select item 943337412.

OXTR^High stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling

Liang Ding, Yong Fu, Nisha Zhu, Mengxiang Zhao, Zhuang Ding, Xiaoxin Zhang, Yuxian Song, Yue Jing, Qian Zhang, Sheng Chen, Xiaofeng Huang, Lorraine A O’Reilly, John Silke, Qingang Hu, Yanhong Ni

Nat Commun. 2022; 13: 5124. Published online 2022 Aug 31. doi: 10.1038/s41467-022-32787-y

PMCID:: PMC9433374

Abstract Article PDF–6.4M

Select item 930837413.

CD36 and ERK5 link dyslipidemia to apoptotic-like platelet procoagulant function

Moua Yang, Roy L. Silverstein

Curr Opin Hematol. Author manuscript; available in PMC 2022 Jul 23.

Published in final edited form as: Curr Opin Hematol. 2019 Sep; 26(5): 357–365. doi: 10.1097/MOH.0000000000000522

PMCID:: PMC9308374

Abstract Article PDF–1.1M

Select item 911973614.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 853898715.

The Hedgehog-GLI Pathway Regulates MEK5-ERK5 Expression and Activation in Melanoma Cells

Ignazia Tusa, Sinforosa Gagliardi, Alessandro Tubita, Silvia Pandolfi, Alessio Menconi, Matteo Lulli, Persio Dello Sbarba, Barbara Stecca, Elisabetta Rovida

Int J Mol Sci. 2021 Oct; 22(20): 11259. Published online 2021 Oct 19. doi: 10.3390/ijms222011259

PMCID:: PMC8538987

Abstract Article PDF–2.2M

Select item 852893416.

ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression

Kristina Riegel, Hajime Yurugi, Janine Schlöder, Helmut Jonuleit, Manuel Kaulich, Friederike Kirschner, Danielle Arnold-Schild, Stefan Tenzer, Hansjörg Schild, Krishnaraj Rajalingam

Cell Death Dis. 2021 Nov; 12(11): 969. Published online 2021 Oct 20. doi: 10.1038/s41419-021-04257-8

PMCID:: PMC8528934

Abstract Article PDF–1.5M

Select item 851806717.

Extracellular Signal‐Regulated Kinase 5 Regulates the Malignant Phenotype of Cholangiocarcinoma Cells

Alessandra Gentilini, Giulia Lori, Alessandra Caligiuri, Chiara Raggi, Giovanni Di Maira, Mirella Pastore, Benedetta Piombanti, Tiziano Lottini, Annarosa Arcangeli, Stefania Madiai, Nadia Navari, Jesus M. Banales, Sabina Di Matteo, Domenico Alvaro, Lea Duwe, Jesper B. Andersen, Alessandro Tubita, Ignazia Tusa, Luca Di Tommaso, Claudia Campani, Elisabetta Rovida, Fabio Marra

Hepatology. 2021 Oct; 74(4): 2007–2020. Published online 2021 Jul 5. doi: 10.1002/hep.31888

PMCID:: PMC8518067

Abstract Article PDF–941K

Select item 850295418.

Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation

Sivareddy Kotla, Aijun Zhang, Masaki Imanishi, Kyung Ae Ko, Steven H. Lin, Young Jin Gi, Margie Moczygemba, Sevinj Isgandarova, Keri L. Schadler, Caroline Chung, Sarah A. Milgrom, Jose Banchs, Syed Wamique Yusuf, Diana N. Amaya, Huifang Guo, Tamlyn N. Thomas, Ying H. Shen, Anita Deswal, Joerg Herrmann, Eugenie S. Kleinerman, Mark L. Entman, John P. Cooke, Giovanni Schifitto, Sanjay B. Maggirwar, Elena McBeath, Anisha A. Gupte, Sunil Krishnan, Zarana S. Patel, Yisang Yoon, Jared K. Burks, Keigi Fujiwara, Paul S. Brookes, Nhat-Tu Le, Dale J. Hamilton, Jun-ichi Abe

Redox Biol. 2021 Nov; 47: 102132. Published online 2021 Sep 20. doi: 10.1016/j.redox.2021.102132

PMCID:: PMC8502954

Abstract Article PDF–12M

Select item 842379519.

Reciprocal regulation of endothelial–mesenchymal transition by MAPK7 and EZH2 in intimal hyperplasia and coronary artery disease

Byambasuren Vanchin, Marloes Sol, Rutger A. F. Gjaltema, Marja Brinker, Bianca Kiers, Alexandre C. Pereira, Martin C. Harmsen, Jan-Renier A. J. Moonen, Guido Krenning

Sci Rep. 2021; 11: 17764. Published online 2021 Sep 7. doi: 10.1038/s41598-021-97127-4

PMCID:: PMC8423795

Abstract Article PDF–5.3M

Select item 819573720.

The extracellular-regulated protein kinase 5 (ERK5) enhances metastatic burden in triple-negative breast cancer through focal adhesion protein kinase (FAK)-mediated regulation of cell adhesion

Qiuping Xu, Jingwei Zhang, Brian A. Telfer, Hao Zhang, Nisha Ali, Fuhui Chen, Blanca Risa, Adam J. Pearson, Wei Zhang, Katherine G. Finegan, Ahmet Ucar, Emanuele Giurisato, Cathy Tournier

Oncogene. 2021; 40(23): 3929–3941. Published online 2021 May 12. doi: 10.1038/s41388-021-01798-2

PMCID:: PMC8195737

Abstract Article PDF–4.0M

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PMC Links for GEO Profiles (Select 103646044) (123)
PMC
Mus musculus mST3Gal VI mRNA for alpha2,3-sialyltransferase, complete cds
Mus musculus mST3Gal VI mRNA for alpha2,3-sialyltransferase, complete cds
gi|17939933|dbj|AB063326.1|

Nucleotide
Mus musculus RIKEN cDNA 2310005G13 gene, mRNA (cDNA clone MGC:198789 IMAGE:90543...
Mus musculus RIKEN cDNA 2310005G13 gene, mRNA (cDNA clone MGC:198789 IMAGE:9054370), complete cds
gi|219521101|gb|BC172084.1|

Nucleotide
Chain H, T-complex protein 1 subunit eta
Chain H, T-complex protein 1 subunit eta
gi|2484083100|pdb|7X0A|H

Protein

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