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Select item 111723391.

ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins

Kasper J. Mygind, Denise Nikodemus, Sebastian Gnosa, Ramya Kweder, Nicolai J. Wewer Albrechtsen, Marie Kveiborg, Janine T. Erler, Reidar Albrechtsen

Int J Mol Sci. 2024 Jun; 25(11): 5871. Published online 2024 May 28. doi: 10.3390/ijms25115871

PMCID:: PMC11172339

Abstract Article PDF–2.5M

Select item 111718012.

Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry

Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland

Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686

PMCID:: PMC11171801

Abstract Article PDF–3.1M

Select item 111419353.

Blocking the angiopoietin-2–dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis

Lydia Meder, Charlotte Isabelle Orschel, Christoph Julius Otto, Mirjam Koker, Johannes Brägelmann, Meryem S. Ercanoglu, Sabrina Dähling, Anik Compes, Carolin Selenz, Marieke Nill, Felix Dietlein, Alexandra Florin, Marie-Lisa Eich, Sven Borchmann, Margarete Odenthal, Raquel Blazquez, Frank Hilberg, Florian Klein, Michael Hallek, Reinhard Büttner, H. Christian Reinhardt, Roland T. Ullrich

JCI Insight. 2024 May 22; 9(10): e166402. Published online 2024 May 22. doi: 10.1172/jci.insight.166402

PMCID:: PMC11141935

Abstract Article PDF–6.7M

Select item 110860524.

Integrin β1 is a key determinant of the expression of angiotensin-converting enzyme 2 (ACE2) in the kidney epithelial cells

Md Saimon Mia, Delowar Hossain, Emerson Woodbury, Sean Kelleher, Riya. J. Palamuttam, Reena Rao, Preston Steen, Yagna PR Jarajapu, Sijo Mathew

Eur J Cell Biol. Author manuscript; available in PMC 2024 May 10.

Published in final edited form as: Eur J Cell Biol. 2023 Jun; 102(2): 151316. Published online 2023 Apr 18. doi: 10.1016/j.ejcb.2023.151316

PMCID:: PMC11086052

Abstract Article PDF–1.9M

Select item 110634025.

Interactions between integrin α9β1 and VCAM-1 promote neutrophil hyperactivation and mediate poststroke DVT

Nilesh Pandey, Harpreet Kaur, Mehul R. Chorawala, Sumit Kumar Anand, Lakshmi Chandaluri, Megan E. Butler, Richa Aishwarya, Shiva J. Gaddam, Xinggui Shen, Mabruka Alfaidi, Jian Wang, Xiaolu Zhang, Kavitha Beedupalli, Md. Shenuarin Bhuiyan, Mohammad Alfrad Nobel Bhuiyan, Prabandh Buchhanolla, Prashant Rai, Rahul Shah, Himanshu Chokhawala, J. Dedrick Jordan, Tarek Magdy, A. Wayne Orr, Karen Y. Stokes, Oren Rom, Nirav Dhanesha

Blood Adv. 2024 May 14; 8(9): 2104–2117. Published online 2024 Mar 27. doi: 10.1182/bloodadvances.2023012282

PMCID:: PMC11063402

Abstract Article PDF–4.8M

Select item 110552406.

Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease

Junhua Huang, Chuanmei Zhao, Shuwan Zhang

BMC Pediatr. 2024; 24: 285. Published online 2024 Apr 27. doi: 10.1186/s12887-024-04766-3

PMCID:: PMC11055240

Abstract Article PDF–2.2M

Select item 110342357.

β1 Integrin triggering affects leukemic cell line sensitivity to natural killer cells

Gonzalo Rubio, Xabier Ferez, Ana Mora, Jesus Galvez, Antonio Chicano, Pilar Garcia-Peñarrubia

Cancer Immunol Immunother. 2002 May; 51(3): 130–138. Published online 2002 Feb 28. doi: 10.1007/s00262-002-0264-8

PMCID:: PMC11034235

Abstract Article PDF–182K

Select item 109646838.

A decrease in integrin α5β1/FAK is associated with increased apoptosis of aortic smooth muscle cells in acute type a aortic dissection

Mingming Xue, Lingyu Xing, Yilin Yang, Mian Shao, Fengqing Liao, Feixiang Xu, Yumei Chen, Sheng Wang, Bin Chen, Chenling Yao, Guorong Gu, Chaoyang Tong

BMC Cardiovasc Disord. 2024; 24: 180. Published online 2024 Mar 26. doi: 10.1186/s12872-024-03778-2

PMCID:: PMC10964683

Abstract Article PDF–4.4M

Select item 109168669.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 1085081810.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 1081190511.

Integrinβ-1 in disorders and cancers: molecular mechanisms and therapeutic targets

Chen Su, Jie Mo, Shuilin Dong, Zhibin Liao, Bixiang Zhang, Peng Zhu

Cell Commun Signal. 2024; 22: 71. Published online 2024 Jan 26. doi: 10.1186/s12964-023-01338-3

PMCID:: PMC10811905

Abstract Article PDF–5.2M

Select item 1080460112.

Cancer-associated fibroblast-derived extracellular vesicles promote lymph node metastases in oral cavity squamous cell carcinoma by encapsulating ITGB1 and BMI1

Tianzhu Lv, Hongjing Liu, Ling Mao, Yanrong Song, Lili Liao, Kun Zhong, Binbin Shuai, Yingkun Luo, Tingting Guo, Wentao Huang, Shenyingjie Zhang

BMC Cancer. 2024; 24: 113. Published online 2024 Jan 22. doi: 10.1186/s12885-024-11855-0

PMCID:: PMC10804601

Abstract Article PDF–19M

Select item 1079990313.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 1064152414.

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis

Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley

J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295

PMCID:: PMC10641524

Abstract Article PDF–3.8M

Select item 1062918515.

The characteristics and the multiple functions of integrin β1 in human cancers

Li Sun, Shuwei Guo, Yiping Xie, Yongliang Yao

J Transl Med. 2023; 21: 787. Published online 2023 Nov 6. doi: 10.1186/s12967-023-04696-1

PMCID:: PMC10629185

Abstract Article PDF–2.2M

Select item 1062778616.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 1059376317.

Knockdown of lncRNA MALAT1 attenuates renal interstitial fibrosis through miR-124-3p/ITGB1 axis

Weiping Xia, Xiang Chen, Zewu Zhu, Hequn Chen, Bingsheng Li, Kangning Wang, Li Huang, Zhi Liu, Zhi Chen

Sci Rep. 2023; 13: 18076. Published online 2023 Oct 23. doi: 10.1038/s41598-023-45188-y

PMCID:: PMC10593763

Abstract Article PDF–6.7M

Select item 1042528418.

TMTC1 promotes invasiveness of ovarian cancer cells through integrins β1 and β4

Ting-Chih Yeh, Neng-Yu Lin, Chin-Yu Chiu, Tzu-Wen Hsu, Hsin-Yi Wu, Hsuan-Yu Lin, Chi-Hau Chen, Min-Chuan Huang

Cancer Gene Ther. 2023; 30(8): 1134–1143. Published online 2023 May 23. doi: 10.1038/s41417-023-00625-y

PMCID:: PMC10425284

Abstract Article PDF–2.7M

Select item 1032325219.

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families

Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell

J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468

PMCID:: PMC10323252

Abstract Article

Select item 1023742220.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

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