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Select item 103109211.

AXL/Gas6 signaling mechanisms in the hypothalamic-pituitary-gonadal axis

Pardis Mohammadzadeh, Gregory C. Amberg

Front Endocrinol (Lausanne) 2023; 14: 1212104. Published online 2023 Jun 15. doi: 10.3389/fendo.2023.1212104

PMCID:: PMC10310921

Abstract Article PDF–1.0M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101916223.

Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis

Zihao Yao, Weizhong Qi, Hongbo Zhang, Zhicheng Zhang, Liangliang Liu, Yan Shao, Hua Zeng, Jianbin Yin, Haoyan Pan, Xiongtian Guo, Anling Liu, Daozhang Cai, Xiaochun Bai, Haiyan Zhang

eLife. 2023; 12: e83069. Published online 2023 May 5. doi: 10.7554/eLife.83069

PMCID:: PMC10191622

Abstract Article PDF–19M

Select item 100729064.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 97696985.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 96778566.

Growth Arrest-Specific 6 in Chromophobe Renal Cell Carcinoma

Marie Mikuteit, Stefanie Zschäbitz, Maximilian Erlmeier, Michael Autenrieth, Wilko Weichert, Arndt Hartmann, Sandra Steffens, Franziska Erlmeier

Oncology. 2022 Oct; 100(10): 536–541. Published online 2022 Jun 27. doi: 10.1159/000525601

PMCID:: PMC9677856

Abstract Article

Select item 93681997.

GAS6/TAM signaling pathway controls MICA expression in multiple myeloma cells

Andrea Kosta, Abdelilah Mekhloufi, Lorenzo Lucantonio, Alessandra Zingoni, Alessandra Soriani, Marco Cippitelli, Angela Gismondi, Francesca Fazio, Maria Teresa Petrucci, Angela Santoni, Helena Stabile, Cinzia Fionda

Front Immunol. 2022; 13: 942640. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.942640

PMCID:: PMC9368199

Abstract Article PDF–1.4M

Select item 91355978.

Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation

Agata Poświata, Kamila Kozik, Marta Miączyńska, Daria Zdżalik-Bielecka

Cell Mol Life Sci. 2022 Jun; 79(6): 316. Published online 2022 May 27. doi: 10.1007/s00018-022-04312-3

PMCID:: PMC9135597

Abstract Article PDF–10M

Select item 91257479.

Growth Arrest Specific-6 and Axl Coordinate Inflammation and Hypertension

Justin P. Van Beusecum, Natalia R. Barbaro, Charles D. Smart, David M. Patrick, Roxana Loperena, Shilin Zhao, Mingfang Ao, Liang Xiao, Cyndya A. Shibao, David G. Harrison

Circ Res. Author manuscript; available in PMC 2022 Nov 12.

Published in final edited form as: Circ Res. 2021 Nov 12; 129(11): 975–991. Published online 2021 Sep 27. doi: 10.1161/CIRCRESAHA.121.319643

PMCID:: PMC9125747

Abstract Article PDF–2.4M

Select item 910523510.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151

PMCID:: PMC9105235

Abstract Article PDF–5.8M

Select item 907040811.

Baseline Plasma Gas6 Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID-19 Patients

Stelvio Tonello, Manuela Rizzi, Erica Matino, Martina Costanzo, Giuseppe Francesco Casciaro, Alessandro Croce, Eleonora Rizzi, Erika Zecca, Anita Pedrinelli, Veronica Vassia, Raffaella Landi, Mattia Bellan, Luigi Mario Castello, Rosalba Minisini, Venkata Ramana Mallela, Davide D'Onghia, Gian Carlo Avanzi, Mario Pirisi, Daniele Lilleri, Pier Paolo Sainaghi

Dis Markers. 2022; 2022: 1568352. Published online 2022 Apr 29. doi: 10.1155/2022/1568352

PMCID:: PMC9070408

Abstract Article PDF–483K

Select item 887003712.

Immunological Aspects of AXL/GAS‐6 in the Context of Human Liver Regeneration

Gregor Ortmayr, Laura Brunnthaler, David Pereyra, Heidemarie Huber, Jonas Santol, Benedikt Rumpf, Sina Najarnia, Rory Smoot, Daphni Ammon, Thomas Sorz, Fabian Fritsch, Michael Schodl, Astrid Voill‐Glaninger, Barbara Weitmayr, Manuela Födinger, Martin Klimpfinger, Thomas Gruenberger, Alice Assinger, Wolfgang Mikulits, Patrick Starlinger

Hepatol Commun. 2022 Mar; 6(3): 576–592. Published online 2021 Dec 24. doi: 10.1002/hep4.1832

PMCID:: PMC8870037

Abstract Article PDF–924K

Select item 855290713.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011