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Items: 14

Select item 81650301.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73832342.

Human Labor Pain Is Influenced by the Voltage-Gated Potassium Channel K_V6.4 Subunit

Michael C. Lee, Michael S. Nahorski, James R.F. Hockley, Van B. Lu, Gillian Ison, Luke A. Pattison, Gerard Callejo, Kaitlin Stouffer, Emily Fletcher, Christopher Brown, Ichrak Drissi, Daniel Wheeler, Patrik Ernfors, David Menon, Frank Reimann, Ewan St. John Smith, C. Geoffrey Woods

Cell Rep. 2020 Jul 21; 32(3): 107941. Published online 2020 Jul 21. doi: 10.1016/j.celrep.2020.107941

PMCID:: PMC7383234

Abstract Article

Select item 55316113.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 46239784.

Modulation of Closed−State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4−AP Induced Potentiation

Jeroen I. Stas, Elke Bocksteins, Alain J. Labro, Dirk J. Snyders

PLoS One. 2015; 10(10): e0141349. Published online 2015 Oct 27. doi: 10.1371/journal.pone.0141349

PMCID:: PMC4623978

Abstract Article PDF–1.7M

Select item 46172115.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 45252876.

Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels

Jens-Peter David, Jeroen I. Stas, Nicole Schmitt, Elke Bocksteins

Sci Rep. 2015; 5: 12813. Published online 2015 Aug 5. doi: 10.1038/srep12813

PMCID:: PMC4525287

Abstract Article PDF–1.7M

Select item 33497347.

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

Caroline S. Fox, Yongmei Liu, Charles C. White, Mary Feitosa, Albert V. Smith, Nancy Heard-Costa, Kurt Lohman, GIANT Consortium, MAGIC Consortium, GLGC Consortium, Andrew D. Johnson, Meredith C. Foster, Danielle M. Greenawalt, Paula Griffin, Jinghong Ding, Anne B. Newman, Fran Tylavsky, Iva Miljkovic, Stephen B. Kritchevsky, Lenore Launer, Melissa Garcia, Gudny Eiriksdottir, J. Jeffrey Carr, Vilmunder Gudnason, Tamara B. Harris, L. Adrienne Cupples, Ingrid B. Borecki

PLoS Genet. 2012 May; 8(5): e1002695. Published online 2012 May 10. doi: 10.1371/journal.pgen.1002695

PMCID:: PMC3349734

Abstract Article PDF–377K

Select item 31780598.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 28964649.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 279723310.

Conserved Negative Charges in the N-terminal Tetramerization Domain Mediate Efficient Assembly of Kv2.1 and Kv2.1/Kv6.4 Channels

Elke Bocksteins, Alain J. Labro, Evy Mayeur, Tine Bruyns, Jean-Pierre Timmermans, Dirk Adriaensen, Dirk J. Snyders

J Biol Chem. 2009 Nov 13; 284(46): 31625–31634. Published online 2009 Aug 28. doi: 10.1074/jbc.M109.039479

PMCID:: PMC2797233

Abstract Article PDF–2.7M

Select item 146417211.

Domain analysis of Kv6.3, an electrically silent channel

Natacha Ottschytsch, Adam L Raes, Jean-Pierre Timmermans, Dirk J Snyders

J Physiol. 2005 Nov 1; 568(Pt 3): 737–747. Published online 2005 Aug 11. doi: 10.1113/jphysiol.2005.090142

PMCID:: PMC1464172

Abstract Article PDF–453K

Select item 52892812.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 13924113.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 12300714.

Obligatory heterotetramerization of three previously uncharacterized Kv channel α-subunits identified in the human genome

N. Ottschytsch, A. Raes, D. Van Hoorick, D. J. Snyders

Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12): 7986–7991. doi: 10.1073/pnas.122617999

PMCID:: PMC123007

Abstract Article PDF–455K

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PMC Links for GEO Profiles (Select 101479756) (14)
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Genetics, Medical
Genetics, Medical
A subdiscipline of human genetics which entails the reliable prediction of certain human disorders as a function of the lineage and/or genetic makeup of an individual or of an...<br/>Year introduced: 1980

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