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Items: 1 to 20 of 36

1.
Serum β-synuclein, neurofilament light chain and glial fibrillary acidic protein as prognostic biomarkers in moderate-to-severe acute ischemic stroke
Lorenzo Barba, Christoph Vollmuth, Samir Abu-Rumeileh, Steffen Halbgebauer, Patrick Oeckl, Petra Steinacker, Alexander M. Kollikowski, Cara Schultz, Judith Wolf, Mirko Pham, Michael K. Schuhmann, Peter U. Heuschmann, Karl Georg Haeusler, Guido Stoll, Hermann Neugebauer, Markus Otto
Sci Rep. 2023; 13: 20941. Published online 2023 Nov 28. doi: 10.1038/s41598-023-47765-7
PMCID:
PMC10684607
AbstractArticlePDF–1.5M
2.
Plasma β‐synuclein, GFAP, and neurofilaments in patients with malignant gliomas undergoing surgical and adjuvant therapy
Samir Abu‐Rumeileh, Lorenzo Barba, Matthias Bache, Steffen Halbgebauer, Patrick Oeckl, Petra Steinacker, Antje Güttler, Jacqueline Keßler, Jörg Illert, Christian Strauss, Dirk Vordermark, Markus Otto
Ann Clin Transl Neurol. 2023 Oct; 10(10): 1924–1930. Published online 2023 Aug 23. doi: 10.1002/acn3.51878
PMCID:
PMC10578894
AbstractArticlePDF–646K
3.
Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan
Cell. Author manuscript; available in PMC 2022 Feb 19.
Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041
PMCID:
PMC8857049
AbstractArticlePDF–3.6M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
6.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
7.
Multi-Pronged Interactions Underlie Inhibition of α-Synuclein Aggregation by β-Synuclein
Jonathan K. Williams, Xue Yang, Tamr B. Atieh, Michael P. Olson, Sagar D. Khare, Jean Baum
J Mol Biol. Author manuscript; available in PMC 2019 Aug 3.
Published in final edited form as: J Mol Biol. 2018 Aug 3; 430(16): 2360–2371. Published online 2018 May 18. doi: 10.1016/j.jmb.2018.05.024
PMCID:
PMC6100766
AbstractArticlePDF–916K
8.
Significant Changes in Plasma Alpha-Synuclein and Beta-Synuclein Levels in Male Children with Autism Spectrum Disorder
Wilaiwan Sriwimol, Pornprot Limprasert
Biomed Res Int. 2018; 2018: 4503871. Published online 2018 Apr 8. doi: 10.1155/2018/4503871
PMCID:
PMC5911343
AbstractArticlePDF–858K
9.
A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues
Gina M. Moriarty, Michael P. Olson, Tamr B. Atieh, Maria K. Janowska, Sagar D. Khare, Jean Baum
J Biol Chem. 2017 Sep 29; 292(39): 16368–16379. Published online 2017 Jul 14. doi: 10.1074/jbc.M117.780528
PMCID:
PMC5625065
AbstractArticlePDF–2.4M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
The loss of inhibitory C‐terminal conformations in disease associated P123H β‐synuclein
Maria K. Janowska, Jean Baum
Protein Sci. 2016 Jan; 25(1): 286–294. Published online 2015 Sep 21. doi: 10.1002/pro.2798
PMCID:
PMC4815300
AbstractArticlePDF–1.3M
12.
Association of α-, β-, and γ-Synuclein With Diffuse Lewy Body Disease
Kenya Nishioka, Christian Wider, Carles Vilariño-Güell, Alexandra I. Soto-Ortolaza, Sarah J. Lincoln, Jennifer M. Kachergus, Barbara Jasinska-Myga, Owen A. Ross, Alex Rajput, Christopher A. Robinson, Tanis J. Ferman, Zbigniew K. Wszolek, Dennis W. Dickson, Matthew J. Farrer
Arch Neurol. Author manuscript; available in PMC 2016 Jan 26.
Published in final edited form as: Arch Neurol. 2010 Aug; 67(8): 970–975. doi: 10.1001/archneurol.2010.177
PMCID:
PMC4727539
AbstractArticlePDF–591K
13.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
14.
A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein
Jane R. Allison, Robert C. Rivers, John C. Christodoulou, Michele Vendruscolo, Christopher M. Dobson
Biochemistry. 2014 Nov 25; 53(46): 7170–7183. Published online 2014 Oct 28. doi: 10.1021/bi5009326
PMCID:
PMC4245978
AbstractArticlePDF–4.1M
15.
Molecular Ageing of Alpha- and Beta-Synucleins: Protein Damage and Repair Mechanisms
Vasanthy Vigneswara, Simon Cass, Declan Wayne, Edward L. Bolt, David E. Ray, Wayne G. Carter
PLoS One. 2013; 8(4): e61442. Published online 2013 Apr 22. doi: 10.1371/journal.pone.0061442
PMCID:
PMC3632608
AbstractArticlePDF–7.3M
16.
In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells
Ulf Dettmer, Andrew J. Newman, Eric S. Luth, Tim Bartels, Dennis Selkoe
J Biol Chem. 2013 Mar 1; 288(9): 6371–6385. Published online 2013 Jan 14. doi: 10.1074/jbc.M112.403311
PMCID:
PMC3585072
AbstractArticlePDF–3.0M
17.
Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein
Akio Sekigawa, Masayo Fujita, Kazunari Sekiyama, Yoshiki Takamatsu, Taku Hatano, Edward Rockenstein, Albert R La Spada, Eliezer Masliah, Makoto Hashimoto
Mol Brain. 2012; 5: 34. Published online 2012 Sep 26. doi: 10.1186/1756-6606-5-34
PMCID:
PMC3546907
AbstractArticlePDF–2.6M
18.
Biochemical and Computational Analysis Of LNX1 Interacting Proteins
Cheryl D. Wolting, Emily K. Griffiths, Renu Sarao, Brittany C. Prevost, Leanne E. Wybenga-Groot, C. Jane McGlade
PLoS One. 2011; 6(11): e26248. Published online 2011 Nov 8. doi: 10.1371/journal.pone.0026248
PMCID:
PMC3210812
AbstractArticlePDF–1.5M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-Homologous Kinase (CHK) and Identification of β-Synuclein as a Potential CHK Physiological Substrate
Kim K. Ia, Grace R. Jeschke, Yang Deng, Mohd Aizuddin Kamaruddin, Nicholas A. Williamson, Denis B. Scanlon, Janetta G. Culvenor, Mohammed Iqbal Hossain, Anthony W. Purcell, Sheng Liu, Hong-Jian Zhu, Bruno Catimel, Benjamin E. Turk, Heung-Chin Cheng
Biochemistry. Author manuscript; available in PMC 2012 Aug 9.
Published in final edited form as: Biochemistry. 2011 Aug 9; 50(31): 6667–6677. Published online 2011 Jul 18. doi: 10.1021/bi2001938
PMCID:
PMC3156789
AbstractArticlePDF–1.0M

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