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Select item 99442701.

MTSS1 curtails lung adenocarcinoma immune evasion by promoting AIP4-mediated PD-L1 monoubiquitination and lysosomal degradation

Yuan Wang, Zhenchang Jia, Chenxi Liang, Yunfei He, Min Cong, Qiuyao Wu, Pu Tian, Dasa He, Xiang Miao, Beibei Sun, Yue Yin, Chao Peng, Feng Yao, Da Fu, Yajun Liang, Peiyuan Zhang, Hua Xiong, Guohong Hu

Cell Discov. 2023; 9: 20. Published online 2023 Feb 21. doi: 10.1038/s41421-022-00507-x

PMCID:: PMC9944270

Abstract Article PDF–3.2M

Select item 97383202.

LINC00491 Facilitates Tumor Progression of Lung Adenocarcinoma via Wnt/β-Catenin-Signaling Pathway by Regulating MTSS1 Ubiquitination

Huimin Wan, Tingting Lin, Mengtian Shan, Jingjing Lu, Zhongliang Guo

Cells. 2022 Dec; 11(23): 3737. Published online 2022 Nov 23. doi: 10.3390/cells11233737

PMCID:: PMC9738320

Abstract Article PDF–4.4M

Select item 84786503.

Downregulation of MTSS1 in acute myeloid leukemia is associated with a poor prognosis, chemotherapy resistance, and disease aggressiveness

Alexander Michael Grandits, Chi Huu Nguyen, Angela Schlerka, Hubert Hackl, Heinz Sill, Julia Etzler, Elizabeth Heyes, Dagmar Stoiber, Florian Grebien, Gerwin Heller, Rotraud Wieser

Leukemia. 2021; 35(10): 2827–2839. Published online 2021 Mar 29. doi: 10.1038/s41375-021-01224-2

PMCID:: PMC8478650

Abstract Article PDF–1.8M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 74814185.

A reciprocal feedback of Myc and lncRNA MTSS1-AS contributes to extracellular acidity-promoted metastasis of pancreatic cancer

Yuhang Hu, Fan Wang, Fengyu Xu, Kaifeng Fang, Zhi Fang, Xiaoming Shuai, Kailin Cai, Jinhuang Chen, Ping Hu, Ding Chen, Peng Xu, Chaojie Hu, Zhu Zeng, Jianxin Zhong, Wei Li, Jiang Tang, Mengqi Huang, Yong Zhao, Chunyou Wang, Gang Zhao

Theranostics. 2020; 10(22): 10120–10140. Published online 2020 Aug 8. doi: 10.7150/thno.49147

PMCID:: PMC7481418

Abstract Article PDF–4.9M

Select item 73940266.

Circular RNA SFMBT2 Inhibits the Proliferation and Metastasis of Glioma Cells Through Mir-182-5p/Mtss1 Pathway

Shoudan Zhang, Wanxiang Qin, Shuo Yang, Ning Guan, Xin Sui, Wenshi Guo

Technol Cancer Res Treat. 2020; 19: 1533033820945799. Published online 2020 Jul 30. doi: 10.1177/1533033820945799

PMCID:: PMC7394026

Abstract Article PDF–1.3M

Select item 67979547.

Long non-coding RNA MEG3 suppresses the growth of glioma cells by regulating the miR-96-5p/MTSS1 signaling pathway

Shoudan Zhang, Wenshi Guo

Mol Med Rep. 2019 Nov; 20(5): 4215–4225. Published online 2019 Sep 10. doi: 10.3892/mmr.2019.10659

PMCID:: PMC6797954

Abstract Article PDF–1.2M

Select item 64841288.

Differential interactions of missing in metastasis and insulin receptor tyrosine kinase substrate with RAB proteins in the endocytosis of CXCR4

Lushen Li, Shaneen S. Baxter, Peng Zhao, Ning Gu, Xi Zhan

J Biol Chem. 2019 Apr 19; 294(16): 6494–6505. Published online 2019 Feb 26. doi: 10.1074/jbc.RA118.006071

PMCID:: PMC6484128

Abstract Article PDF–2.8M

Select item 58328219.

MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer

Jayakumar Vadakekolathu, Shaymaa Ismael Kadhim Al-Juboori, Catherine Johnson, Anne Schneider, Magdalena Elżbieta Buczek, Anna Di Biase, Alan Graham Pockley, Graham Roy Ball, Desmond George Powe, Tarik Regad

Cell Death Dis. 2018 Mar; 9(3): 344. Published online 2018 Mar 1. doi: 10.1038/s41419-018-0364-9

Correction in:: Cell Death Dis. 2020 Mar; 11(3): 205.

PMCID:: PMC5832821

Abstract Article PDF–2.8M

Select item 571425410.

PTEN-Dependent Stabilization of MTSS1 Inhibits Metastatic Phenotype in Pancreatic Ductal Adenocarcinoma

Ann E. Zeleniak, Wei Huang, Melissa L. Fishel, Reginald Hill

Neoplasia. 2018 Jan; 20(1): 12–24. Published online 2017 Nov 23. doi: 10.1016/j.neo.2017.10.004

PMCID:: PMC5714254

Abstract Article PDF–1.2M

Select item 566790711.

Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis

E Agarwal, CM Robb, LM Smith, MG Brattain, J Wang, JD Black, S Chowdhury

Oncogene. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Oncogene. 2017 Jun 1; 36(22): 3104–3118. Published online 2017 Jan 9. doi: 10.1038/onc.2016.460

PMCID:: PMC5667907

Abstract Article PDF–3.2M

Select item 539978712.

Missing-in-metastasis protein downregulates CXCR4 by promoting ubiquitylation and interaction with small Rab GTPases

Lushen Li, Shaneen S. Baxter, Ning Gu, Min Ji, Xi Zhan

J Cell Sci. 2017 Apr 15; 130(8): 1475–1485. doi: 10.1242/jcs.198937

PMCID:: PMC5399787

Abstract Article

Select item 536997813.

Loss of MTSS1 results in increased metastatic potential in pancreatic cancer

Ann E Zeleniak, Wei Huang, Mary K Brinkman, Melissa L Fishel, Reginald Hill

Oncotarget. 2017 Mar 7; 8(10): 16473–16487. Published online 2017 Jan 27. doi: 10.18632/oncotarget.14869

PMCID:: PMC5369978

Abstract Article PDF–9.0M

Select item 506724514.

The SH3 domain distinguishes the role of I-BAR proteins IRTKS and MIM in chemotactic response to serum

Lushen Li, Hongyu Liu, Shaneen S. Baxter, Ning Gu, Min Ji, Xi Zhan

Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Oct 28.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Oct 28; 479(4): 787–792. Published online 2016 Sep 28. doi: 10.1016/j.bbrc.2016.09.131

PMCID:: PMC5067245

Abstract Article PDF–981K

Select item 445395615.

Downregulation of MTSS1 expression is an independent prognosticator in squamous cell carcinoma of the lung

G Kayser, A Csanadi, S Kakanou, A Prasse, A Kassem, E Stickeler, B Passlick, A zur Hausen

Br J Cancer. 2015 Mar 3; 112(5): 866–873. Published online 2015 Jan 27. doi: 10.1038/bjc.2015.2

PMCID:: PMC4453956

Abstract Article PDF–1.4M

Select item 444071216.

Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

Mirle Schemionek, Behzad Kharabi Masouleh, Yvonne Klaile, Utz Krug, Katja Hebestreit, Claudia Schubert, Martin Dugas, Thomas Büchner, Bernhard Wörmann, Wolfgang Hiddemann, Wolfgang E. Berdel, Tim H. Brümmendorf, Carsten Müller-Tidow, Steffen Koschmieder

PLoS One. 2015; 10(5): e0125783. Published online 2015 May 21. doi: 10.1371/journal.pone.0125783

PMCID:: PMC4440712

Abstract Article PDF–1.3M

Select item 441803017.

Heritability and genetic association analysis of cognition in the Diabetes Heart Study

Amanda J. Cox, Christina E. Hugenschmidt, Laura M. Raffield, Carl D. Langefeld, Barry I. Freedman, Jeff D. Williamson, Fang-Chi Hsu, Donald W. Bowden

Neurobiol Aging. Author manuscript; available in PMC 2015 May 4.

Published in final edited form as: Neurobiol Aging. 2014 Aug; 35(8): 1958.e3–1958.e12. Published online 2014 Mar 11. doi: 10.1016/j.neurobiolaging.2014.03.005

PMCID:: PMC4418030

Abstract Article PDF–1.5M

Select item 431221318.

Missing-in-Metastasis regulates cell motility and invasion via PTPδ-mediated changes in SRC activity

Fauzia Chaudhary, Robert Lucito, Nicholas K. Tonks

Biochem J. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Biochem J. 2015 Jan 1; 465(1): 89–101. doi: 10.1042/BJ20140573

PMCID:: PMC4312213

Abstract Article PDF–1.9M

Select item 429537519.

Substrate Trapping Proteomics Reveals Targets of the βTrCP2/FBXW11 Ubiquitin Ligase

Tai Young Kim, Priscila F. Siesser, Kent L. Rossman, Dennis Goldfarb, Kathryn Mackinnon, Feng Yan, XianHua Yi, Michael J. MacCoss, Randall T. Moon, Channing J. Der, Michael B. Major

Mol Cell Biol. 2015 Jan; 35(1): 167–181. Prepublished online 2014 Oct 20. Published online 2014 Dec 9. doi: 10.1128/MCB.00857-14

PMCID:: PMC4295375

Abstract Article PDF–5.6M

Select item 392683120.

SCF^β-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration

Jiateng Zhong, Shavali Shaik, Lixin Wan, Adriana E. Tron, Zhiwei Wang, Liankun Sun, Hiroyuki Inuzuka, Wenyi Wei

Oncotarget. 2013 Dec; 4(12): 2339–2353. Published online 2013 Nov 6. doi: 10.18632/oncotarget.1446

PMCID:: PMC3926831

Abstract Article PDF–2.6M

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