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Select item 111085571.

MALT1 is not alone after all: identification of novel paracaspases

Paco Hulpiau, Yasmine Driege, Jens Staal, Rudi Beyaert

Cell Mol Life Sci. 2016 Mar; 73(5): 1103–1116. Published online 2015 Sep 16. doi: 10.1007/s00018-015-2041-9

PMCID:: PMC11108557

Abstract Article PDF–2.3M

Select item 110638392.

Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application

Firas M. Safa, Terri Rasmussen, Lorena Fontan, Min Xia, Ari Melnick, Adrian Wiestner, Patricia Lobelle-Rich, Jan A. Burger, Yara Mouawad, Hana Safah, Erik K Flemington, Nakhle S. Saba

Haematologica. 2024 May 1; 109(5): 1348–1358. Published online 2023 Sep 28. doi: 10.3324/haematol.2023.283178

PMCID:: PMC11063839

Abstract Article PDF–4.6M

Select item 109604713.

Inhibition of the MALT1-LPCAT3 axis protects cartilage degeneration and osteoarthritis

Vijay Kondreddy, Rajkumar Banerjee, B. L. A. Prabhavathi Devi, Kathirvel Muralidharan, Selvakumar Piramanayagam

Cell Commun Signal. 2024; 22: 189. Published online 2024 Mar 22. doi: 10.1186/s12964-024-01547-4

PMCID:: PMC10960471

Abstract Article PDF–2.4M

Select item 109023464.

Long-term monitoring of gastric mucosa-associated lymphoid tissue lymphoma in patients with extra copies of the MALT1 gene

Masaya Iwamuro, Ryuta Takenaka, Koji Miyahara, Shotaro Okanoue, Masao Yoshioka, Chihiro Sakaguchi, Kumiko Yamamoto, Yoshinari Kawai, Tatsuya Toyokawa, Takehiro Tanaka, Motoyuki Otsuka

Sci Rep. 2024; 14: 4953. Published online 2024 Feb 29. doi: 10.1038/s41598-024-55663-9

PMCID:: PMC10902346

Abstract Article PDF–1012K

Select item 107338375.

Oncogene-induced MALT1 protease activity drives posttranscriptional gene expression in malignant lymphomas

Nicole Wimberger, Franziska Ober, Göksu Avar, Michael Grau, Wendan Xu, Georg Lenz, Michael P. Menden, Daniel Krappmann

Blood. 2023 Dec 7; 142(23): 1985–2001. Published online 2023 Aug 28. doi: 10.1182/blood.2023021299

PMCID:: PMC10733837

Abstract Article

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101599717.

Localization and expression profiles of gingival monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT-1)

Lili Yu, Yigit Firatli, Samira Elmanfi, Mervi Gürsoy, Meltem Özdemir Kabalak, Gökhan Kasnak, Pirkko Pussinen, Floris J. Bikker, Feriha Caglayan, Erhan Firatli, Ulvi Kahraman Gürsoy

Clin Oral Investig. 2023; 27(5): 2065–2074. Published online 2023 Apr 3. doi: 10.1007/s00784-023-05010-5

PMCID:: PMC10159971

Abstract Article PDF–1.1M

Select item 101384568.

Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing

Leonie Wittner, Lukas Wagener, Jakob J. Wiese, Iris Stolzer, Susanne M. Krug, Elisabeth Naschberger, Rene Jackstadt, Rudi Beyaert, Raja Atreya, Anja A. Kühl, Gregor Sturm, Miguel Gonzalez-Acera, Jay V. Patankar, Christoph Becker, Britta Siegmund, Zlatko Trajanoski, Beate Winner, Markus F. Neurath, Michael Schumann, Claudia Günther

Int J Mol Sci. 2023 Apr; 24(8): 7402. Published online 2023 Apr 17. doi: 10.3390/ijms24087402

PMCID:: PMC10138456

Abstract Article PDF–9.1M

Select item 100177929.

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, Saskia A. G. M. Cillessen, Richard J. Bende, Carel J. M. van Noesel, Marie José Kersten, Steven T. Pals, Marcel Spaargaren

Blood Cancer J. 2023 Dec; 13(1): 37. Published online 2023 Mar 15. doi: 10.1038/s41408-023-00809-7

PMCID:: PMC10017792

Abstract Article PDF–3.7M

Select item 988838210.

Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma

Vivian Changying Jiang, Yang Liu, Junwei Lian, Shengjian Huang, Alexa Jordan, Qingsong Cai, Ruitao Lin, Fangfang Yan, Joseph McIntosh, Yijing Li, Yuxuan Che, Zhihong Chen, Jovanny Vargas, Maria Badillo, John Nelson Bigcal, Heng-Huan Lee, Wei Wang, Yixin Yao, Lei Nie, Christopher R. Flowers, Michael Wang

J Clin Invest. 2023 Feb 1; 133(3): e165694. Published online 2023 Feb 1. doi: 10.1172/JCI165694

PMCID:: PMC9888382

Abstract Article PDF–2.3M

Select item 952337611.

The Gab2–MALT1 axis regulates thromboinflammation and deep vein thrombosis

Vijay Kondreddy, Shiva Keshava, Kaushik Das, Jhansi Magisetty, L. Vijaya Mohan Rao, Usha R. Pendurthi

Blood. 2022 Sep 29; 140(13): 1549–1564. doi: 10.1182/blood.2022016424

PMCID:: PMC9523376

Abstract Article

Select item 951011012.

Assignment of IVL-Methyl side chain of the ligand-free monomeric human MALT1 paracaspase-IgL₃ domain in solution

Xiao Han, Maria Levkovets, Dmitry Lesovoy, Renhua Sun, Johan Wallerstein, Tatyana Sandalova, Tatiana Agback, Adnane Achour, Peter Agback, Vladislav Yu. Orekhov

Biomol NMR Assign. 2022; 16(2): 363–371. Published online 2022 Sep 12. doi: 10.1007/s12104-022-10105-3

PMCID:: PMC9510110

Abstract Article PDF–1.8M

Select item 948193313.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 936769114.

MALT1 regulates Th2 and Th17 differentiation via NF-κB and JNK pathways, as well as correlates with disease activity and treatment outcome in rheumatoid arthritis

Qiubo Wang, Yapeng Wang, Qingyang Liu, Ying Chu, Rui Mi, Fengying Jiang, Jingjing Zhao, Kelong Hu, Ran Luo, Yufeng Feng, Harrison Lee, Dong Zhou, Jingyi Mi, Ruoyu Deng

Front Immunol. 2022; 13: 913830. Published online 2022 Jul 28. doi: 10.3389/fimmu.2022.913830

PMCID:: PMC9367691

Abstract Article PDF–6.3M

Select item 934295815.

A nucleation barrier spring-loads the CBM signalosome for binary activation

Alejandro Rodriguez Gama, Tayla Miller, Jeffrey J Lange, Jay R Unruh, Randal Halfmann

eLife. 2022; 11: e79826. Published online 2022 Jun 21. doi: 10.7554/eLife.79826

PMCID:: PMC9342958

Abstract Article PDF–7.3M

Select item 927996716.

MALT1 positively relates to Th17 cells, inflammation/activity degree, and its decrement along with treatment reflects TNF inhibitor response in ankylosing spondylitis patients

Jie Yuan, Lei Xiang, Feng Wang, Lin Zhang, Gaozhan Liu, Xiuli Chang, Anbing Zhang, Ying Tao

J Clin Lab Anal. 2022 Jul; 36(7): e24472. Published online 2022 May 27. doi: 10.1002/jcla.24472

PMCID:: PMC9279967

Abstract Article PDF–3.3M

Select item 916916617.

Mucosa‐associated lymphoid tissue lymphoma translocation protein 1 in rheumatoid arthritis: Longitudinal change after treatment and correlation with treatment efficacy of tumor necrosis factor inhibitors

Feng Wang, Gaozhan Liu, Lei Xiang, Jie Yuan, Ying Tao, Lin Zhang, Anbing Zhang, Xiuli Chang

J Clin Lab Anal. 2022 Jun; 36(6): e24449. Published online 2022 May 2. doi: 10.1002/jcla.24449

PMCID:: PMC9169166

Abstract Article PDF–3.9M

Select item 910523518.

Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser

Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151