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Items: 1 to 20 of 40

1.
Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA
Hidetaka Niizuma, Adam C. Searleman, Shugaku Takeda, Scott A. Armstrong, Christopher Y. Park, Emily H. Cheng, James J. Hsieh
JCI Insight. 2021 Aug 9; 6(15): e149382. Published online 2021 Aug 9. doi: 10.1172/jci.insight.149382
PMCID:
PMC8410044
AbstractArticlePDF–5.8M
2.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
3.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency
Yunlong Xiang, Yu Zhang, Qianhua Xu, Chen Zhou, Bofeng Liu, Zhenhai Du, Ke Zhang, Bingjie Zhang, Xiaoxiao Wang, Srimonta Gayen, Ling Liu, Yao Wang, Yuanyuan Li, Qiujun Wang, Sundeep Kalantry, Lei Li, Wei Xie
Nat Genet. Author manuscript; available in PMC 2020 Jul 15.
Published in final edited form as: Nat Genet. 2020 Jan; 52(1): 95–105. Published online 2019 Dec 16. doi: 10.1038/s41588-019-0545-1
PMCID:
PMC7362285
AbstractArticlePDF–2.8M
6.
MLL1 is required for PAX7 expression and satellite cell self-renewal in mice
Gregory C. Addicks, Caroline E. Brun, Marie-Claude Sincennes, John Saber, Christopher J. Porter, A. Francis Stewart, Patricia Ernst, Michael A. Rudnicki
Nat Commun. 2019; 10: 4256. Published online 2019 Sep 18. doi: 10.1038/s41467-019-12086-9
PMCID:
PMC6751293
AbstractArticlePDF–3.8M
7.
Histone-Methyltransferase MLL2 (KMT2B) Is Required for Memory Formation in Mice
Cemil Kerimoglu, Roberto C. Agis-Balboa, Andrea Kranz, Roman Stilling, Sanaz Bahari-Javan, Eva Benito-Garagorri, Rashi Halder, Susanne Burkhardt, Adrian Francis Stewart, Andre Fischer
J Neurosci. 2013 Feb 20; 33(8): 3452–3464. doi: 10.1523/JNEUROSCI.3356-12.2013
Correction in:
J Neurosci. 2013 Apr 17; 33(16): 7108.
PMCID:
PMC6619533
AbstractArticlePDF–1.7M
8.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland
Nature. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360
PMCID:
PMC6283663
AbstractArticlePDF–4.9M
9.
KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes
Giulia Barbagiovanni, Pierre-Luc Germain, Michael Zech, Sina Atashpaz, Pietro Lo Riso, Agnieszka D’Antonio-Chronowska, Erika Tenderini, Massimiliano Caiazzo, Sylvia Boesch, Robert Jech, Bernhard Haslinger, Vania Broccoli, Adrian Francis Stewart, Juliane Winkelmann, Giuseppe Testa
Cell Rep. 2018 Oct 23; 25(4): 988–1001. Published online 2018 Oct 23. doi: 10.1016/j.celrep.2018.09.067
PMCID:
PMC6218204
AbstractArticle
10.
MLL2, not MLL1, Plays a Major Role in Sustaining MLL-rearranged Acute Myeloid Leukemia
Yufei Chen, Konstantinos Anastassiadis, Andrea Kranz, A. Francis Stewart, Kathrin Arndt, Claudia Waskow, Akihiko Yokoyama, Kenneth Jones, Tobias Neff, Yoo Lee, Patricia Ernst
Cancer Cell. Author manuscript; available in PMC 2018 Jun 12.
Published in final edited form as: Cancer Cell. 2017 Jun 12; 31(6): 755–770.e6. doi: 10.1016/j.ccell.2017.05.002
PMCID:
PMC5598468
AbstractArticlePDF–3.1M
11.
Rebalancing gene haploinsufficiency in vivo by targeting chromatin
Filomena Gabriella Fulcoli, Monica Franzese, Xiangyang Liu, Zhen Zhang, Claudia Angelini, Antonio Baldini
Nat Commun. 2016; 7: 11688. Published online 2016 Jun 3. doi: 10.1038/ncomms11688
PMCID:
PMC4895808
AbstractArticlePDF–2.0M
12.
The LMO2 oncogene regulates DNA replication in hematopoietic cells
Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang
Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113
PMCID:
PMC4747768
AbstractArticlePDF–1.0M
13.
Neuronal Kmt2a/Mll1 Histone Methyltransferase Is Essential for Prefrontal Synaptic Plasticity and Working Memory
Mira Jakovcevski, Hongyu Ruan, Erica Y. Shen, Aslihan Dincer, Behnam Javidfar, Qi Ma, Cyril J. Peter, Iris Cheung, Amanda C. Mitchell, Yan Jiang, Cong L. Lin, Venu Pothula, A. Francis Stewart, Patricia Ernst, Wei-Dong Yao, Schahram Akbarian
J Neurosci. 2015 Apr 1; 35(13): 5097–5108. doi: 10.1523/JNEUROSCI.3004-14.2015
PMCID:
PMC4380991
AbstractArticlePDF–1.5M
14.
Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription
Shugaku Takeda, Satoru Sasagawa, Toshinao Oyama, Adam C. Searleman, Todd D. Westergard, Emily H. Cheng, James J. Hsieh
J Clin Invest. 2015 Mar 2; 125(3): 1203–1214. Published online 2015 Feb 9. doi: 10.1172/JCI77075
PMCID:
PMC4362222
AbstractArticlePDF–4.7M
15.
Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis
Jingwen Wu, Jianqiang Bao, Minkyung Kim, Shuiqiao Yuan, Chong Tang, Huili Zheng, Grant S. Mastick, Chen Xu, Wei Yan
Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28): E2851–E2857. Published online 2014 Jun 30. doi: 10.1073/pnas.1407777111
PMCID:
PMC4104921
AbstractArticlePDF–1.8M
16.
Cleavage of TFIIA by Taspase1 Activates TRF2-Specified Mammalian Male Germ Cell Programs
Toshinao Oyama, Satoru Sasagawa, Shugaku Takeda, Rex A. Hess, Paul M. Lieberman, Emily H. Cheng, James J. Hsieh
Dev Cell. Author manuscript; available in PMC 2014 Oct 28.
Published in final edited form as: Dev Cell. 2013 Oct 28; 27(2): 188–200. doi: 10.1016/j.devcel.2013.09.025
PMCID:
PMC3947863
AbstractArticlePDF–3.0M
17.
H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
Ji-Eun Lee, Chaochen Wang, Shiliyang Xu, Young-Wook Cho, Lifeng Wang, Xuesong Feng, Anne Baldridge, Vittorio Sartorelli, Lenan Zhuang, Weiqun Peng, Kai Ge
eLife. 2013; 2: e01503. Published online 2013 Dec 24. doi: 10.7554/eLife.01503
PMCID:
PMC3869375
AbstractArticlePDF–5.8M
18.
The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells
Deqing Hu, Alexander S. Garruss, Xin Gao, Marc A. Morgan, Malcolm Cook, Edwin R. Smith, Ali Shilatifard
Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Nat Struct Mol Biol. 2013 Sep; 20(9): 1093–1097. Published online 2013 Aug 11. doi: 10.1038/nsmb.2653
PMCID:
PMC3805109
AbstractArticlePDF–1.2M
19.
A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal
Alessia Gagliardi, Nicholas P Mullin, Zi Ying Tan, Douglas Colby, Anastasia I Kousa, Florian Halbritter, Jason T Weiss, Anastasia Felker, Karel Bezstarosti, Rebecca Favaro, Jeroen Demmers, Silvia K Nicolis, Simon R Tomlinson, Raymond A Poot, Ian Chambers
EMBO J. 2013 Aug 14; 32(16): 2231–2247. Published online 2013 Jul 26. doi: 10.1038/emboj.2013.161
PMCID:
PMC3746198
AbstractArticlePDF–2.9M
20.
Mutations in Mll2, an H3K4 Methyltransferase, Result in Insulin Resistance and Impaired Glucose Tolerance in Mice
Michelle Goldsworthy, Nathan L. Absalom, David Schröter, Helen C. Matthews, Debora Bogani, Lee Moir, Anna Long, Christopher Church, Alison Hugill, Quentin M. Anstee, Rob Goldin, Mark Thursz, Florian Hollfelder, Roger D. Cox
PLoS One. 2013; 8(6): e61870. Published online 2013 Jun 24. doi: 10.1371/journal.pone.0061870
PMCID:
PMC3691224
AbstractArticlePDF–1.7M

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