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Select item 70606191.

Phylogenetically informative mutations in genes implicated in antibiotic resistance in Mycobacterium tuberculosis complex

Matthias Merker, Thomas A. Kohl, Ivan Barilar, Sönke Andres, Philip W. Fowler, Erja Chryssanthou, Kristian Ängeby, Pontus Jureen, Danesh Moradigaravand, Julian Parkhill, Sharon J. Peacock, Thomas Schön, Florian P. Maurer, Timothy Walker, Claudio Köser, Stefan Niemann

Genome Med. 2020; 12: 27. Published online 2020 Mar 6. doi: 10.1186/s13073-020-00726-5

PMCID:: PMC7060619

Article PDF–1.4M

Select item 70499022.

Comparative genomics shows differences in the electron transport and carbon metabolic pathways of Mycobacterium africanum relative to Mycobacterium tuberculosis and suggests an adaptation to low oxygen tension

Boatema Ofori-Anyinam, Abi Janet Riley, Tijan Jobarteh, Ensa Gitteh, Binta Sarr, Tutty Isatou Faal-Jawara, Leen Rigouts, Madikay Senghore, Aderemi Kehinde, Nneka Onyejepu, Martin Antonio, Bouke C. de Jong, Florian Gehre, Conor J. Meehan

Tuberculosis (Edinb) 2020 Jan; 120: 101899. doi: 10.1016/j.tube.2020.101899

PMCID:: PMC7049902

Article

Select item 70458443.

Multidrug- and Extensively Drug-Resistant Mycobacterium tuberculosis Beijing Clades, Ukraine, 2015

Matthias Merker, Elena Nikolaevskaya, Thomas A. Kohl, Barbara Molina-Moya, Olha Pavlovska, Patrik Brännberg, Andrii Dudnyk, Valentyna Stokich, Ivan Barilar, Iryna Marynova, Tetiana Filipova, Cristina Prat, Anders Sjöstedt, Jose Dominguez, Olena Rzhepishevska, Stefan Niemann

Emerg Infect Dis. 2020 Mar; 26(3): 481–490. doi: 10.3201/eid2603.190525

PMCID:: PMC7045844

Article PDF–2.5M

Select item 70356734.

Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania

Bugwesa Z. Katale, Peter M. Mbelele, Nsiande A. Lema, Susana Campino, Stephen E. Mshana, Mark M. Rweyemamu, Jody E. Phelan, Julius D. Keyyu, Mtebe Majigo, Erasto V. Mbugi, Hazel M. Dockrell, Taane G. Clark, Mecky I. Matee, Stellah Mpagama

BMC Genomics. 2020; 21: 174. Published online 2020 Feb 21. doi: 10.1186/s12864-020-6577-1

PMCID:: PMC7035673

Article PDF–1.0M

Select item 70331305.

Comparative in-silico proteomic analysis discerns potential granuloma proteins of Yersinia pseudotuberculosis

Manisha Aswal, Anjali Garg, Neelja Singhal, Manish Kumar

Sci Rep. 2020; 10: 3036. Published online 2020 Feb 20. doi: 10.1038/s41598-020-59924-1

PMCID:: PMC7033130

Article PDF–2.3M

Select item 70327346.

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering

Brendon M. Lee, Liam K. Harold, Deepak V. Almeida, Livnat Afriat-Jurnou, Htin Lin Aung, Brian M. Forde, Kiel Hards, Sacha J. Pidot, F. Hafna Ahmed, A. Elaaf Mohamed, Matthew C. Taylor, Nicholas P. West, Timothy P. Stinear, Chris Greening, Scott A. Beatson, Eric L. Nuermberger, Gregory M. Cook, Colin J. Jackson

PLoS Pathog. 2020 Feb; 16(2): e1008287. Published online 2020 Feb 7. doi: 10.1371/journal.ppat.1008287

PMCID:: PMC7032734

Article PDF–3.3M

Select item 70294897.

Genome-wide identification of the context-dependent sRNA expression in Mycobacterium tuberculosis

Vimla Kany G. Ami, Rami Balasubramanian, Shubhada R. Hegde

BMC Genomics. 2020; 21: 167. Published online 2020 Feb 18. doi: 10.1186/s12864-020-6573-5

PMCID:: PMC7029489

Article PDF–3.3M

Select item 70281118.

New insights into the mycobacterial PE and PPE proteins provide a framework for future research

Louis S. Ates

Mol Microbiol. 2020 Jan; 113(1): 4–21. Published online 2019 Nov 24. doi: 10.1111/mmi.14409

PMCID:: PMC7028111

Article PDF–1.3M

Select item 70214699.

A Universal, Genomewide GuideFinder for CRISPR/Cas9 Targeting in Microbial Genomes

Michelle Spoto, Changhui Guan, Elizabeth Fleming, Julia Oh

mSphere. 2020 Jan-Feb; 5(1): e00086-20. Published online 2020 Feb 12. doi: 10.1128/mSphere.00086-20

PMCID:: PMC7021469

Article PDF–2.1M

Select item 701259610.

Previously undetected super-spreading of Mycobacterium tuberculosis revealed by deep sequencing

Robyn S Lee, Jean-François Proulx, Fiona McIntosh, Marcel A Behr, William P Hanage

eLife. 2020; 9: e53245. Published online 2020 Feb 4. doi: 10.7554/eLife.53245

PMCID:: PMC7012596

Article PDF–863K

Select item 701115911.

SEVERITY OF TB CLASSIFIED BY MODIFIED BANDIM TB SCORING ASSOCIATES WITH THE SPECIFIC SEQUENCE OF ESXA GENES IN MDR-TB PATIENTS

Desak Nyoman Surya Suameitria Dewi, Ni Made Mertaniasih, Soedarsono

Afr J Infect Dis. 2020; 14(1): 8–15. Published online 2020 Jan 8. doi: 10.21010/ajid.v14i1.2

PMCID:: PMC7011159

Article PDF–213K

Select item 700423712.

Antibiotic resistance prediction for Mycobacterium tuberculosis from genome sequence data with Mykrobe

Martin Hunt, Phelim Bradley, Simon Grandjean Lapierre, Simon Heys, Mark Thomsit, Michael B. Hall, Kerri M. Malone, Penelope Wintringer, Timothy M. Walker, Daniela M. Cirillo, Iñaki Comas, Maha R. Farhat, Phillip Fowler, Jennifer Gardy, Nazir Ismail, Thomas A. Kohl, Vanessa Mathys, Matthias Merker, Stefan Niemann, Shaheed Vally Omar, Vitali Sintchenko, Grace Smith, Dick van Soolingen, Philip Supply, Sabira Tahseen, Mark Wilcox, Irena Arandjelovic, Tim E. A. Peto, Derrick W. Crook, Zamin Iqbal

Version 1. Wellcome Open Res. 2019; 4: 191. Published online 2019 Dec 2. doi: 10.12688/wellcomeopenres.15603.1

PMCID:: PMC7004237

Article PDF–1.4M

Select item 700072413.

Phylogenomic Perspective on a Unique Mycobacterium bovis Clade Dominating Bovine Tuberculosis Infections among Cattle and Buffalos in Northern Brazil

Marília Lima da Conceição, Emilyn Costa Conceição, Ismari Perini Furlaneto, Sandro Patroca da Silva, Arthur Emil dos Santos Guimarães, Pedro Gomes, María Laura Boschiroli, Lorraine Michelet, Thomas Andreas Kohl, Katharina Kranzer, Loreno da Costa Francez, Luana Nepomuceno Gondim Costa Lima, Isabel Portugal, João Perdigão, Karla Valéria Batista Lima

Sci Rep. 2020; 10: 1747. Published online 2020 Feb 4. doi: 10.1038/s41598-020-58398-5

PMCID:: PMC7000724

Article PDF–3.4M

Select item 699991114.

New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis

Andréanne Lupien, Caroline Shi-Yan Foo, Svetlana Savina, Anthony Vocat, Jérémie Piton, Natalia Monakhova, Andrej Benjak, Dirk A. Lamprecht, Adrie J. C. Steyn, Kevin Pethe, Vadim A. Makarov, Stewart T. Cole

PLoS Pathog. 2020 Jan; 16(1): e1008270. Published online 2020 Jan 23. doi: 10.1371/journal.ppat.1008270

PMCID:: PMC6999911

Article PDF–2.2M

Select item 698641515.

Detection of Novel Gene Mutations Associated with Pyrazinamide Resistance in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates in Southern China

HM Adnan Hameed, Yaoju Tan, Md Mahmudul Islam, Zhili Lu, Chiranjibi Chhotaray, Shuai Wang, Zhiyong Liu, Cuiting Fang, Shouyong Tan, Wing Wai Yew, Nanshan Zhong, Jianxiong Liu, Tianyu Zhang

Infect Drug Resist. 2020; 13: 217–227. Published online 2020 Jan 22. doi: 10.2147/IDR.S230774

PMCID:: PMC6986415

Article PDF–613K

Select item 698609016.

QuantTB – a method to classify mixed Mycobacterium tuberculosis infections within whole genome sequencing data

Christine Anyansi, Arlin Keo, Bruce J. Walker, Timothy J. Straub, Abigail L. Manson, Ashlee M. Earl, Thomas Abeel

BMC Genomics. 2020; 21: 80. Published online 2020 Jan 28. doi: 10.1186/s12864-020-6486-3

PMCID:: PMC6986090

Article PDF–1.4M

Select item 698509917.

Key Transitions in the Evolution of Rapid and Slow Growing Mycobacteria Identified by Comparative Genomics

Nathan L. Bachmann, Rauf Salamzade, Abigail L. Manson, Richard Whittington, Vitali Sintchenko, Ashlee M. Earl, Ben J. Marais

Front Microbiol. 2019; 10: 3019. Published online 2020 Jan 21. doi: 10.3389/fmicb.2019.03019

PMCID:: PMC6985099

Article PDF–7.3M

Select item 697930418.

Draft Genome Sequence of an Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis from Nepal

Sanjay S. Gautam, Kelvin W. C. Leong, Manoj Pradhan, Y. Ibotomba Singh, Sagar K. Rajbhandari, Gokarna R. Ghimire, Krishna Adhikari, Uma Shrestha, Raina Chaudhary, Gyanendra Ghimire, Sundar Khadka, Ronan F. O’Toole

Microbiol Resour Announc. 2020 Jan; 9(4): e01404-19. Published online 2020 Jan 23. doi: 10.1128/MRA.01404-19

PMCID:: PMC6979304

Article PDF–123K

Select item 697831419.

Epidemiological cut-offs for Sensititre susceptibility testing of Mycobacterium tuberculosis: interpretive criteria cross validated with whole genome sequencing

Nazir A. Ismail, Farzana Ismail, Lavania Joseph, Netricia Govender, Linsay Blows, Koné Kaniga, Shaheed V. Omar

Sci Rep. 2020; 10: 1013. Published online 2020 Jan 23. doi: 10.1038/s41598-020-57992-x

PMCID:: PMC6978314

Article PDF–2.2M

Select item 697468020.

Genomic Insights Into the Mycobacterium kansasii Complex: An Update

Tomasz Jagielski, Paulina Borówka, Zofia Bakuła, Jakub Lach, Błażej Marciniak, Anna Brzostek, Jarosław Dziadek, Mikołaj Dziurzyński, Lian Pennings, Jakko van Ingen, Manca Žolnir-Dovč, Dominik Strapagiel

Front Microbiol. 2019; 10: 2918. Published online 2020 Jan 15. doi: 10.3389/fmicb.2019.02918

PMCID:: PMC6974680

Article PDF–10M

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