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Select item 70699811.

Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration

Insup Choi, Yuanxi Zhang, Steven P. Seegobin, Mathilde Pruvost, Qian Wang, Kerry Purtell, Bin Zhang, Zhenyu Yue

Nat Commun. 2020; 11: 1386. Published online 2020 Mar 13. doi: 10.1038/s41467-020-15119-w

PMCID:: PMC7069981

Abstract Article PDF–5.7M

Select item 70282782.

Aberrant DNA methylation of the toll-like receptors 2 and 6 genes in patients with obstructive sleep apnea

Kuo-Tung Huang, Yung-Che Chen, Chia-Cheng Tseng, Huang-Chih Chang, Mao-Chang Su, Ting-Ya Wang, Yong-Yong Lin, Yi-Xin Zheng, Jen-Chieh Chang, Chien-Hung Chin, Chang-Chun Hsiao, Meng-Chih Lin

PLoS One. 2020; 15(2): e0228958. Published online 2020 Feb 18. doi: 10.1371/journal.pone.0228958

PMCID:: PMC7028278

Abstract Article PDF–1.6M

Select item 70271953.

Systematic Nucleotide Exchange Analysis of ESTs From the Human Cancer Genome Project Report: Origins of 347 Unknown ESTs Indicate Putative Transcription of Non-Coding Genomic Regions

Ganesh Warthi, Pierre-Edouard Fournier, Hervé Seligmann

Front Genet. 2020; 11: 42. Published online 2020 Feb 11. doi: 10.3389/fgene.2020.00042

PMCID:: PMC7027195

Abstract Article PDF–1.2M

Select item 70168904.

HIF1α/TET1 Pathway Mediates Hypoxia-Induced Adipocytokine Promoter Hypomethylation in Human Adipocytes

Mohamed M. Ali, Shane A. Phillips, Abeer M. Mahmoud

Cells. 2020 Jan; 9(1): 134. Published online 2020 Jan 6. doi: 10.3390/cells9010134

PMCID:: PMC7016890

Abstract Article PDF–2.2M

Select item 70160255.

Overexpression of alpha-synuclein promotes both cell proliferation and cell toxicity in human SH-SY5Y neuroblastoma cells

Noela Rodríguez-Losada, Javier de la Rosa, María Larriva, Rune Wendelbo, José A. Aguirre, Javier S. Castresana, Santiago J. Ballaz

J Adv Res. 2020 May; 23: 37–45. Published online 2020 Jan 22. doi: 10.1016/j.jare.2020.01.009

PMCID:: PMC7016025

Abstract Article PDF–1.5M

Select item 69883206.

NFкB is a critical transcriptional regulator of atypical cadherin FAT1 in glioma

Chitrangda Srivastava, Khushboo Irshad, Yakhlesh Gupta, Chitra Sarkar, Ashish Suri, Parthaprasad Chattopadhyay, Subrata Sinha, Kunzang Chosdol

BMC Cancer. 2020; 20: 62. Published online 2020 Jan 28. doi: 10.1186/s12885-019-6435-1

PMCID:: PMC6988320

Abstract Article PDF–3.3M

Select item 68987887.

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

David Liu, Bastian Schilling, Derek Liu, Antje Sucker, Elisabeth Livingstone, Livnat Jerby-Arnon, Lisa Zimmer, Ralf Gutzmer, Imke Satzger, Carmen Loquai, Stephan Grabbe, Natalie Vokes, Claire A. Margolis, Jake Conway, Meng Xiao He, Haitham Elmarakeby, Felix Dietlein, Diana Miao, Adam Tracy, Helen Gogas, Simone M. Goldinger, Jochen Utikal, Christian U. Blank, Ricarda Rauschenberg, Dagmar von Bubnoff, Angela Krackhardt, Benjamin Weide, Sebastian Haferkamp, Felix Kiecker, Ben Izar, Levi Garraway, Aviv Regev, Keith Flaherty, Annette Paschen, Eliezer M. Van Allen, Dirk Schadendorf

Nat Med. 2019; 25(12): 1916–1927. Published online 2019 Dec 2. doi: 10.1038/s41591-019-0654-5

Correction in:: Nat Med. 2020; 26(7): 1147.

PMCID:: PMC6898788

Abstract Article PDF–3.4M

Select item 68930318.

Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts

Timo Strohäker, Byung Chul Jung, Shu-Hao Liou, Claudio O. Fernandez, Dietmar Riedel, Stefan Becker, Glenda M. Halliday, Marina Bennati, Woojin S. Kim, Seung-Jae Lee, Markus Zweckstetter

Nat Commun. 2019; 10: 5535. Published online 2019 Dec 4. doi: 10.1038/s41467-019-13564-w

PMCID:: PMC6893031

Abstract Article PDF–2.0M

Select item 68583429.

Comprehensive Analysis of the Expression Profiles of Long Non-Coding RNAs with Associated ceRNA Network Involved in the Colon Cancer Staging and Progression

Meini Wu, Wenliang Li, Fengchang Huang, Jing Sun, Kang ping Li, Jiandong Shi, Jingyu Yang, Jianfang Li, Yanhan Li, Ningzhu Hu, YunZhang Hu

Sci Rep. 2019; 9: 16910. Published online 2019 Nov 15. doi: 10.1038/s41598-019-52883-2

PMCID:: PMC6858342

Abstract Article PDF–4.1M

Select item 679288910.

Persyn, a Member of the Synuclein Family, Has a Distinct Pattern of Expression in the Developing Nervous System

Vladimir L. Buchman, Hamish J. A. Hunter, Luzia G. P. Pinõn, Jane Thompson, Eugenia M. Privalova, Natalia N. Ninkina, Alun M. Davies

J Neurosci. 1998 Nov 15; 18(22): 9335–9341. doi: 10.1523/JNEUROSCI.18-22-09335.1998

PMCID:: PMC6792889

Abstract Article PDF–630K

Select item 678593411.

Circ-SMARCA5 suppresses progression of multiple myeloma by targeting miR-767-5p

Haiyan Liu, Yan Wu, Shunye Wang, Jie Jiang, Chenlu Zhang, Yijing Jiang, Xingfeng Wang, Lewen Hong, Hongming Huang

BMC Cancer. 2019; 19: 937. Published online 2019 Oct 10. doi: 10.1186/s12885-019-6088-0

PMCID:: PMC6785934

Abstract Article PDF–7.6M

Select item 672584012.

Neurological and Neurodegenerative Alterations in a Transgenic Mouse Model Expressing Human α-Synuclein under Oligodendrocyte Promoter: Implications for Multiple System Atrophy

Clifford W. Shults, Edward Rockenstein, Leslie Crews, Anthony Adame, Michael Mante, Gabriel Larrea, Makoto Hashimoto, David Song, Takeshi Iwatsubo, Kyoko Tsuboi, Eliezer Masliah

J Neurosci. 2005 Nov 16; 25(46): 10689–10699. doi: 10.1523/JNEUROSCI.3527-05.2005

PMCID:: PMC6725840

Abstract Article PDF–878K

Select item 670132813.

GNPDA2 Gene Affects Adipogenesis and Alters the Transcriptome Profile of Human Adipose-Derived Mesenchymal Stem Cells

Lijun Wu, Feifei Ma, Xiaoyuan Zhao, Mei-Xian Zhang, Jianxin Wu, Jie Mi

Int J Endocrinol. 2019; 2019: 9145452. Published online 2019 Aug 1. doi: 10.1155/2019/9145452

PMCID:: PMC6701328

Abstract Article PDF–4.0M

Select item 667418214.

Endogenous α-Synuclein Is Induced by Valproic Acid through Histone Deacetylase Inhibition and Participates in Neuroprotection against Glutamate-Induced Excitotoxicity

Yan Leng, De-Maw Chuang

J Neurosci. 2006 Jul 12; 26(28): 7502–7512. doi: 10.1523/JNEUROSCI.0096-06.2006

PMCID:: PMC6674182

Abstract Article PDF–1.4M

Select item 667118715.

Neurodegeneration and Motor Dysfunction in a Conditional Model of Parkinson's Disease

Silke Nuber, Elisabeth Petrasch-Parwez, Beate Winner, Jürgen Winkler, Stephan von Hörsten, Thorsten Schmidt, Jana Boy, Melanie Kuhn, Huu P. Nguyen, Peter Teismann, Jörg B. Schulz, Manuela Neumann, Bernd J. Pichler, Gerald Reischl, Carsten Holzmann, Ina Schmitt, Antje Bornemann, Wilfried Kuhn, Frank Zimmermann, Antonio Servadio, Olaf Riess

J Neurosci. 2008 Mar 5; 28(10): 2471–2484. doi: 10.1523/JNEUROSCI.3040-07.2008

PMCID:: PMC6671187

Abstract Article PDF–1.1M

Select item 662996416.

Latrophilins: A Neuro-Centric View of an Evolutionary Conserved Adhesion G Protein-Coupled Receptor Subfamily

Ana L. Moreno-Salinas, Monserrat Avila-Zozaya, Paul Ugalde-Silva, David A. Hernández-Guzmán, Fanis Missirlis, Antony A. Boucard

Front Neurosci. 2019; 13: 700. Published online 2019 Jul 9. doi: 10.3389/fnins.2019.00700

PMCID:: PMC6629964

Abstract Article PDF–5.8M

Select item 650301317.

Genetic analysis of pharmacogenomic VIP variants in the Blang population from Yunnan Province of China

Chan Zhang, Weiwei Guo, Yujing Cheng, Qi Li, Xin Yang, Run Dai, Linhao Zhu, Wanlu Chen

Mol Genet Genomic Med. 2019 May; 7(5): e574. Published online 2019 Apr 5. doi: 10.1002/mgg3.574

PMCID:: PMC6503013

Abstract Article PDF–1.2M

Select item 646565718.

Integrated bioinformatics analysis of key genes involved in progress of colon cancer

Haojie Yang, Jiong Wu, Jingjing Zhang, Zhigang Yang, Wei Jin, Ying Li, Lei Jin, Lu Yin, Hua Liu, Zhenyi Wang

Mol Genet Genomic Med. 2019 Apr; 7(4): e00588. Published online 2019 Feb 11. doi: 10.1002/mgg3.588

PMCID:: PMC6465657

Abstract Article PDF–1017K

Select item 641836319.

Interaction of germline variants in a family with a history of early‐onset clear cell renal cell carcinoma

Emmanuelle Nicolas, Elena V. Demidova, Waleed Iqbal, Ilya G. Serebriiskii, Ramilia Vlasenkova, Pooja Ghatalia, Yan Zhou, Kim Rainey, Andrea F. Forman, Roland L. Dunbrack, Jr, Erica A. Golemis, Michael J. Hall, Mary B. Daly, Sanjeevani Arora

Mol Genet Genomic Med. 2019 Mar; 7(3): e556. Published online 2019 Jan 24. doi: 10.1002/mgg3.556