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Select item 68935461.

Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China

Susanna K. P. Lau, Hayes K. H. Luk, Antonio C. P. Wong, Rachel Y. Y. Fan, Carol S. F. Lam, Kenneth S. M. Li, Syed Shakeel Ahmed, Franklin W.N. Chow, Jian-Piao Cai, Xun Zhu, Jasper F. W. Chan, Terrence C. K. Lau, Kaiyuan Cao, Mengfeng Li, Patrick C. Y. Woo, Kwok-Yung Yuen

Viruses. 2019 Nov; 11(11): 980. Published online 2019 Oct 24. doi: 10.3390/v11110980

PMCID:: PMC6893546

Abstract Article PDF–4.6M

Select item 65210532.

Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors

Artur Szczepanski, Katarzyna Owczarek, Monika Bzowska, Katarzyna Gula, Inga Drebot, Marek Ochman, Beata Maksym, Zenon Rajfur, Judy A Mitchell, Krzysztof Pyrc

Viruses. 2019 Apr; 11(4): 328. Published online 2019 Apr 5. doi: 10.3390/v11040328

PMCID:: PMC6521053

Abstract Article PDF–28M

Select item 64579313.

A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike

Shuai Xia, Lei Yan, Wei Xu, Anurodh Shankar Agrawal, Abdullah Algaissi, Chien-Te K. Tseng, Qian Wang, Lanying Du, Wenjie Tan, Ian A. Wilson, Shibo Jiang, Bei Yang, Lu Lu

Sci Adv. 2019 Apr; 5(4): eaav4580. Published online 2019 Apr 10. doi: 10.1126/sciadv.aav4580

PMCID:: PMC6457931

Abstract Article PDF–5.2M

Select item 63906314.

Enrichment post-library preparation enhances the sensitivity of high-throughput sequencing-based detection and characterization of viruses from complex samples

Adrian C. Paskey, Kenneth G. Frey, Gary Schroth, Stephen Gross, Theron Hamilton, Kimberly A. Bishop-Lilly

BMC Genomics. 2019; 20: 155. Published online 2019 Feb 26. doi: 10.1186/s12864-019-5543-2

PMCID:: PMC6390631

Abstract Article PDF–3.0M

Select item 60523125.

Discovery and Sequence Analysis of Four Deltacoronaviruses from Birds in the Middle East Reveal Interspecies Jumping with Recombination as a Potential Mechanism for Avian-to-Avian and Avian-to-Mammalian Transmission

Susanna K. P. Lau, Emily Y. M. Wong, Chi-Ching Tsang, Syed Shakeel Ahmed, Rex K. H. Au-Yeung, Kwok-Yung Yuen, Ulrich Wernery, Patrick C. Y. Woo

J Virol. 2018 Aug 1; 92(15): e00265-18. Prepublished online 2018 May 16. Published online 2018 Jul 17. doi: 10.1128/JVI.00265-18

PMCID:: PMC6052312

Abstract Article PDF–2.1M

Select item 58533116.

Prolonged Shedding of Human Coronavirus in Hematopoietic Cell Transplant Recipients: Risk Factors and Viral Genome Evolution

Chikara Ogimi, Alexander L Greninger, Alpana A Waghmare, Jane M Kuypers, Ryan C Shean, Hu Xie, Wendy M Leisenring, Terry L Stevens-Ayers, Keith R Jerome, Janet A Englund, Michael Boeckh

J Infect Dis. 2017 Jul 15; 216(2): 203–209. Published online 2017 May 30. doi: 10.1093/infdis/jix264

PMCID:: PMC5853311

Abstract Article PDF–209K

Select item 55531627.

Discovery of a Highly Divergent Coronavirus in the Asian House Shrew from China Illuminates the Origin of the Alphacoronaviruses

Wen Wang, Xian-Dan Lin, Yong Liao, Xiao-Qing Guan, Wen-Ping Guo, Jian-Guang Xing, Edward C. Holmes, Yong-Zhen Zhang

J Virol. 2017 Sep 1; 91(17): e00764-17. Prepublished online 2017 Jun 21. Published online 2017 Aug 10. doi: 10.1128/JVI.00764-17

PMCID:: PMC5553162

Abstract Article PDF–4.2M

Select item 55296718.

Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1

Xiuyuan Ou, Hongxin Guan, Bo Qin, Zhixia Mu, Justyna A. Wojdyla, Meitian Wang, Samuel R. Dominguez, Zhaohui Qian, Sheng Cui

Nat Commun. 2017; 8: 15216. Published online 2017 May 23. doi: 10.1038/ncomms15216

PMCID:: PMC5529671

Abstract Article PDF–1.5M

Select item 53898649.

Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor

Xing-Yi Ge, Jia-Lu Li, Xing-Lou Yang, Aleksei A. Chmura, Guangjian Zhu, Jonathan H. Epstein, Jonna K. Mazet, Ben Hu, Wei Zhang, Cheng Peng, Yu-Ji Zhang, Chu-Ming Luo, Bing Tan, Ning Wang, Yan Zhu, Gary Crameri, Shu-Yi Zhang, Lin-Fa Wang, Peter Daszak, Zheng-Li Shi

Nature. 2013; 503(7477): 535–538. Published online 2013 Oct 30. doi: 10.1038/nature12711

PMCID:: PMC5389864

Abstract Article PDF–4.6M

Select item 503896510.

A Bat-Derived Putative Cross-Family Recombinant Coronavirus with a Reovirus Gene

Canping Huang, William J. Liu, Wen Xu, Tao Jin, Yingze Zhao, Jingdong Song, Yi Shi, Wei Ji, Hao Jia, Yongming Zhou, Honghua Wen, Honglan Zhao, Huaxing Liu, Hong Li, Qihui Wang, Ying Wu, Liang Wang, Di Liu, Guang Liu, Hongjie Yu, Edward C. Holmes, Lin Lu, George F. Gao

PLoS Pathog. 2016 Sep; 12(9): e1005883. Published online 2016 Sep 27. doi: 10.1371/journal.ppat.1005883

PMCID:: PMC5038965

Abstract Article PDF–4.3M

Select item 487923811.

First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh

S.K.P. Lau, A.K.L. Tsang, S. Shakeel Ahmed, M. Mahbub Alam, Z. Ahmed, P.-C. Wong, K.-Y. Yuen, P.C.Y. Woo

New Microbes New Infect. 2016 May; 11: 54–56. Published online 2016 Mar 3. doi: 10.1016/j.nmni.2016.02.011

PMCID:: PMC4879238

Abstract Article PDF–381K

Select item 483715512.

Development of Monoclonal Antibody and Diagnostic Test for Middle East Respiratory Syndrome Coronavirus Using Cell-Free Synthesized Nucleocapsid Antigen

Yutaro Yamaoka, Shutoku Matsuyama, Shuetsu Fukushi, Satoko Matsunaga, Yuki Matsushima, Hiroyuki Kuroyama, Hirokazu Kimura, Makoto Takeda, Tomoyuki Chimuro, Akihide Ryo

Front Microbiol. 2016; 7: 509. Published online 2016 Apr 20. doi: 10.3389/fmicb.2016.00509

PMCID:: PMC4837155

Abstract Article PDF–3.8M

Select item 478019113.

Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design

Fenghua Wang, Cheng Chen, Wenjie Tan, Kailin Yang, Haitao Yang

Sci Rep. 2016; 6: 22677. Published online 2016 Mar 7. doi: 10.1038/srep22677

PMCID:: PMC4780191

Abstract Article PDF–2.0M

Select item 468284514.

Critical Assessment of the Important Residues Involved in the Dimerization and Catalysis of MERS Coronavirus Main Protease

Bo-Lin Ho, Shu-Chun Cheng, Lin Shi, Ting-Yun Wang, Kuan-I Ho, Chi-Yuan Chou

PLoS One. 2015; 10(12): e0144865. Published online 2015 Dec 14. doi: 10.1371/journal.pone.0144865

PMCID:: PMC4682845

Abstract Article PDF–2.3M

Select item 458017615.

Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination

Susanna K. P. Lau, Yun Feng, Honglin Chen, Hayes K. H. Luk, Wei-Hong Yang, Kenneth S. M. Li, Yu-Zhen Zhang, Yi Huang, Zhi-Zhong Song, Wang-Ngai Chow, Rachel Y. Y. Fan, Syed Shakeel Ahmed, Hazel C. Yeung, Carol S. F. Lam, Jian-Piao Cai, Samson S. Y. Wong, Jasper F. W. Chan, Kwok-Yung Yuen, Hai-Lin Zhang, Patrick C. Y. Woo

J Virol. 2015 Oct 15; 89(20): 10532–10547. Published online 2015 Aug 12. doi: 10.1128/JVI.01048-15

PMCID:: PMC4580176

Abstract Article PDF–8.2M

Select item 450843416.

Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses

Jasper Fuk-Woo Chan, Garnet Kwan-Yue Choi, Alan Ka-Lun Tsang, Kah-Meng Tee, Ho-Yin Lam, Cyril Chik-Yan Yip, Kelvin Kai-Wang To, Vincent Chi-Chung Cheng, Man-Lung Yeung, Susanna Kar-Pui Lau, Patrick Chiu-Yat Woo, Kwok-Hung Chan, Bone Siu-Fai Tang, Kwok-Yung Yuen

J Clin Microbiol. 2015 Aug; 53(8): 2722–2726. Prepublished online 2015 May 27. Published online 2015 Jul 20. doi: 10.1128/JCM.01224-15

PMCID:: PMC4508434

Abstract Article PDF–335K

Select item 447670117.

Host Subtraction, Filtering and Assembly Validations for Novel Viral Discovery Using Next Generation Sequencing Data

Gordon M. Daly, Richard M. Leggett, William Rowe, Samuel Stubbs, Maxim Wilkinson, Ricardo H. Ramirez-Gonzalez, Mario Caccamo, William Bernal, Jonathan L. Heeney

PLoS One. 2015; 10(6): e0129059. Published online 2015 Jun 22. doi: 10.1371/journal.pone.0129059

PMCID:: PMC4476701

Abstract Article PDF–4.7M

Select item 447354518.

Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme

Xingchuan Huang, Wenjuan Dong, Aleksandra Milewska, Anna Golda, Yonghe Qi, Quan K. Zhu, Wayne A. Marasco, Ralph S. Baric, Amy C. Sims, Krzysztof Pyrc, Wenhui Li, Jianhua Sui

J Virol. 2015 Jul 15; 89(14): 7202–7213. Published online 2015 Apr 29. doi: 10.1128/JVI.00854-15