Full text in PMC (nucleotide) for Gene (Select 218203) - PMC

Select item 60921131.

Inactivation of the E3 Ubiquitin Ligase IDOL Attenuates Diet-Induced Obesity and Metabolic Dysfunction in Mice

Nienke M. van Loon, Roelof Ottenhoff, Sander Kooijman, Martina Moeton, Saskia Scheij, Reinout L.P. Roscam Abbing, Marion J.J. Gijbels, Johannes H.M. Levels, Vincenzo Sorrentino, Jimmy F.P. Berbée, Patrick C.N. Rensen, Noam Zelcer

Arterioscler Thromb Vasc Biol. 2018 Aug; 38(8): 1785–1795. Published online 2018 Jun 14. doi: 10.1161/ATVBAHA.118.311168

PMCID:: PMC6092113

Abstract Article PDF–2.5M

Select item 58546422.

(–)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B

Wei Wang, Zheng-Zhu Zhang, Yan Wu, Ru-Qing Wang, Jin-Wu Chen, Jing Chen, Yan Zhang, Ya-Jun Chen, Ming Geng, Zhong-Dong Xu, Min Dai, Jin-Hua Li, Li-Long Pan

Front Pharmacol. 2018; 9: 195. Published online 2018 Mar 9. doi: 10.3389/fphar.2018.00195

Correction in:: Front Pharmacol. 2018; 9: 459.

PMCID:: PMC5854642

Abstract Article PDF–1.1M

Select item 52958213.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 47980444.

Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol

Salam Ibrahim, Suryanarayan Somanathan, Jeffrey Billheimer, James M. Wilson, Daniel J. Rader

Cardiovasc Res. 2016 May 1; 110(1): 23–29. Published online 2016 Jan 19. doi: 10.1093/cvr/cvw010

PMCID:: PMC4798044

Abstract Article PDF–582K

Select item 39899005.

Sustained and Selective Suppression of Intestinal Cholesterol Synthesis by Ro 48-8071, an Inhibitor of 2,3-Oxidosqualene:Lanosterol Cyclase, in the BALB/c Mouse

Jen-Chieh Chuang, Mark A. Valasek, Adam M. Lopez, Kenneth S. Posey, Joyce J. Repa, Stephen D. Turley

Biochem Pharmacol. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Biochem Pharmacol. 2014 Apr 1; 88(3): 351–363. Published online 2014 Jan 31. doi: 10.1016/j.bcp.2014.01.031

PMCID:: PMC3989900

Abstract Article PDF–5.2M

Select item 32099636.

Small Molecule Inhibition of Cytoskeletal Dynamics in Melanoma Tumors Results in Altered Transcriptional Expression Patterns of Key Genes Involved in Tumor Initiation and Progression

CARRIE SPENCER, JOHN MONTALVO, SARAH R. MCLAUGHLIN, BRAD A. BRYAN

Cancer Genomics Proteomics. Author manuscript; available in PMC 2011 Nov 7.

Published in final edited form as: Cancer Genomics Proteomics. 2011 Mar-Apr; 8(2): 77–85.

PMCID:: PMC3209963

Abstract Article PDF–1.2M

Select item 31332287.

Targeted Disruption of the Idol Gene Alters Cellular Regulation of the Low-Density Lipoprotein Receptor by Sterols and Liver X Receptor Agonists

Elena Scotti, Cynthia Hong, Yuko Yoshinaga, Yiping Tu, Yan Hu, Noam Zelcer, Rima Boyadjian, Pieter J. de Jong, Stephen G. Young, Loren G. Fong, Peter Tontonoz

Mol Cell Biol. 2011 May; 31(9): 1885–1893. doi: 10.1128/MCB.01469-10

PMCID:: PMC3133228

Abstract Article PDF–3.1M

Select item 31199188.

Next-generation sequencing of the Chinese hamster ovary microRNA transcriptome: Identification, annotation and profiling of microRNAs as targets for cellular engineering

Matthias Hackl, Tobias Jakobi, Jochen Blom, Daniel Doppmeier, Karina Brinkrolf, Rafael Szczepanowski, Stephan H. Bernhart, Christian Höner zu Siederdissen, Juan A. Hernandez Bort, Matthias Wieser, Renate Kunert, Simon Jeffs, Ivo L. Hofacker, Alexander Goesmann, Alfred Pühler, Nicole Borth, Johannes Grillari

J Biotechnol. 2011 Apr 20; 153(1-2): 62–75. doi: 10.1016/j.jbiotec.2011.02.011

PMCID:: PMC3119918

Abstract Article

Select item 30484039.

Changes in Gene Expression and Cellular Architecture in an Ovarian Cancer Progression Model

Amy L. Creekmore, William T. Silkworth, Daniela Cimini, Roderick V. Jensen, Paul C. Roberts, Eva M. Schmelz

PLoS One. 2011; 6(3): e17676. Published online 2011 Mar 3. doi: 10.1371/journal.pone.0017676

PMCID:: PMC3048403

Abstract Article PDF–2.0M

Select item 295469310.

Intermittent Hypoxia Mobilizes Bone Marrow-Derived Very Small Embryonic-Like Stem Cells and Activates Developmental Transcriptional Programs in Mice

Sina A. Gharib, Ehab A. Dayyat, Abdelnaby Khalyfa, Jinkwan Kim, Heather B. Clair, Magdalena Kucia, David Gozal

Sleep. 2010 Nov 1; 33(11): 1439–1446. doi: 10.1093/sleep/33.11.1439

PMCID:: PMC2954693

Abstract Article PDF–1.7M

Select item 291844711.

Reduced VLDL clearance in Apoe^−/−Npc1^−/− mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels

Minako Ishibashi, David Masson, Marit Westerterp, Nan Wang, Scott Sayers, Rong Li, Carrie L. Welch, Alan R. Tall

J Lipid Res. 2010 Sep; 51(9): 2655–2663. doi: 10.1194/jlr.M006163

PMCID:: PMC2918447

Abstract Article PDF–1.0M

Select item 288838212.

The E3 Ubiquitin Ligase IDOL Induces the Degradation of the Low Density Lipoprotein Receptor Family Members VLDLR and ApoER2

Cynthia Hong, Sarah Duit, Pilvi Jalonen, Ruud Out, Lilith Scheer, Vincenzo Sorrentino, Rima Boyadjian, Kees W. Rodenburg, Edan Foley, Laura Korhonen, Dan Lindholm, Johannes Nimpf, Theo J. C. van Berkel, Peter Tontonoz, Noam Zelcer

J Biol Chem. 2010 Jun 25; 285(26): 19720–19726. Published online 2010 Apr 28. doi: 10.1074/jbc.M110.123729

PMCID:: PMC2888382

Abstract Article PDF–971K

Select item 277752313.

LXR Regulates Cholesterol Uptake through Idol-dependent Ubiquitination of the LDL Receptor

Noam Zelcer, Cynthia Hong, Rima Boyadjian, Peter Tontonoz

Science. Author manuscript; available in PMC 2010 Jan 3.

Published in final edited form as: Science. 2009 Jul 3; 325(5936): 100–104. Published online 2009 Jun 11. doi: 10.1126/science.1168974

PMCID:: PMC2777523

Abstract Article PDF–2.3M

Select item 31099214.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600

PMCID:: PMC310992

Abstract Article PDF–3.4M

Select item 31098015.

Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes

Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki

Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100

PMCID:: PMC310980

Abstract Article PDF–1.4M

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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