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Select item 69396151.

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer’s disease

Jessica L. Hoffman, Sara Faccidomo, Michelle Kim, Seth M. Taylor, Abigail E. Agoglia, Ashley M. May, Evan N. Smith, L.C. Wong, Clyde W. Hodge

Int Rev Neurobiol. Author manuscript; available in PMC 2020 Jan 2.

Published in final edited form as: Int Rev Neurobiol. 2019; 148: 169–230. Published online 2019 Oct 23. doi: 10.1016/bs.irn.2019.10.017

PMCID:: PMC6939615

Abstract Article PDF–2.0M

Select item 67865642.

Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner

Donald J. Joseph, Chunxia Liu, Jun Peng, Ge Liang, Huafeng Wei

PLoS One. 2019; 14(10): e0223509. Published online 2019 Oct 10. doi: 10.1371/journal.pone.0223509

PMCID:: PMC6786564

Abstract Article PDF–4.8M

Select item 67850833.

Bexarotene therapy ameliorates behavioral deficits and induces functional and molecular changes in very-old Triple Transgenic Mice model of Alzheimer´s disease

Jonathan Mauricio Muñoz-Cabrera, Adrián Gabriel Sandoval-Hernández, Andrea Niño, Tatiana Báez, Angie Bustos-Rangel, Gloria Patricia Cardona-Gómez, Alejandro Múnera, Gonzalo Arboleda

PLoS One. 2019; 14(10): e0223578. Published online 2019 Oct 9. doi: 10.1371/journal.pone.0223578

PMCID:: PMC6785083

Abstract Article PDF–4.6M

Select item 67747344.

Presenilin/γ-secretase-dependent EphA3 processing mediates axon elongation through non-muscle myosin IIA

Míriam Javier-Torrent, Sergi Marco, Daniel Rocandio, Maria Pons-Vizcarra, Peter W Janes, Martin Lackmann, Joaquim Egea, Carlos A Saura

eLife. 2019; 8: e43646. Published online 2019 Oct 2. doi: 10.7554/eLife.43646

PMCID:: PMC6774734

Abstract Article PDF–9.8M

Select item 67712775.

Impact of Chronic Risperidone Use on Behavior and Survival of 3xTg-AD Mice Model of Alzheimer’s Disease and Mice With Normal Aging

Virginia Torres-Lista, Secundí López-Pousa, Lydia Giménez-Llort

Front Pharmacol. 2019; 10: 1061. Published online 2019 Sep 24. doi: 10.3389/fphar.2019.01061

PMCID:: PMC6771277

Abstract Article PDF–6.5M

Select item 66741206.

Deletion of Presenilin 1 Hydrophilic Loop Sequence Leads to Impaired γ-Secretase Activity and Exacerbated Amyloid Pathology

Yu Deng, Leonid Tarassishin, Verena Kallhoff, Erica Peethumnongsin, Ling Wu, Yue-Ming Li, Hui Zheng

J Neurosci. 2006 Apr 5; 26(14): 3845–3854. doi: 10.1523/JNEUROSCI.5384-05.2006

PMCID:: PMC6674120

Abstract Article PDF–1.1M

Select item 64337867.

Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of Aβ_1-42 Induced Cognitive Deficit Mice

Yue Zhu, Yiwei Shi, Cheng Cao, Zhenxiang Han, Mengqiu Liu, Mingzhu Qi, Renjie Huang, Ziqiang Zhu, Dawei Qian, Jin-ao Duan

Front Pharmacol. 2019; 10: 258. Published online 2019 Mar 19. doi: 10.3389/fphar.2019.00258

PMCID:: PMC6433786

Abstract Article PDF–3.5M

Select item 57400628.

CRTC1 mediates preferential transcription at neuronal activity-regulated CRE/TATA promoters

Arnaldo Parra-Damas, Laura Rubió-Ferrarons, Jie Shen, Carlos A. Saura

Sci Rep. 2017; 7: 18004. Published online 2017 Dec 21. doi: 10.1038/s41598-017-18215-y

PMCID:: PMC5740062

Abstract Article PDF–4.9M

Select item 57326919.

Prostaglandin I₂ is responsible for ameliorating prostaglandin E₂ stress in stimulating the expression of tumor necrosis factor α in a β-amyloid protein -dependent mechanism

Shao-Qin Zheng, Zi-Yi Gong, Chen-Di Lu, Pu Wang

Oncotarget. 2017 Nov 28; 8(61): 102801–102819. Published online 2017 Jun 13. doi: 10.18632/oncotarget.18462

PMCID:: PMC5732691

Abstract Article PDF–18M

Select item 501302410.

Prostaglandin I₂ upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice

Pu Wang, Pei‐Pei Guan, Jing‐Wen Guo, Long‐Long Cao, Guo‐Biao Xu, Xin Yu, Yue Wang, Zhan‐You Wang

Aging Cell. 2016 Oct; 15(5): 861–871. Published online 2016 May 30. doi: 10.1111/acel.12495

PMCID:: PMC5013024

Abstract Article PDF–2.8M

Select item 475145511.

Prostaglandin I₂ Attenuates Prostaglandin E₂-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism

Pu Wang, Pei-Pei Guan, Xin Yu, Li-Chao Zhang, Ya-Nan Su, Zhan-You Wang

Sci Rep. 2016; 6: 20879. Published online 2016 Feb 12. doi: 10.1038/srep20879

PMCID:: PMC4751455

Abstract Article PDF–3.3M

Select item 402825312.

Overexpression of the IGF-II/M6P Receptor in Mouse Fibroblast Cell Lines Differentially Alters Expression Profiles of Genes Involved in Alzheimer’s Disease-Related Pathology

Yanlin Wang, Gopal Thinakaran, Satyabrata Kar

PLoS One. 2014; 9(5): e98057. Published online 2014 May 20. doi: 10.1371/journal.pone.0098057

PMCID:: PMC4028253

Abstract Article PDF–2.4M

Select item 359629313.

Pathology Associated with AAV Mediated Expression of Beta Amyloid or C100 in Adult Mouse Hippocampus and Cerebellum

Eleanor S. Drummond, Jill Muhling, Ralph N. Martins, Linda K. Wijaya, Erich M. Ehlert, Alan R. Harvey

PLoS One. 2013; 8(3): e59166. Published online 2013 Mar 13. doi: 10.1371/journal.pone.0059166

PMCID:: PMC3596293

Abstract Article PDF–20M

Select item 355850814.

Alterations in Gene Expression in Mutant Amyloid Precursor Protein Transgenic Mice Lacking Niemann-Pick Type C1 Protein

Mahua Maulik, Gopal Thinakaran, Satyabrata Kar

PLoS One. 2013; 8(1): e54605. Published online 2013 Jan 29. doi: 10.1371/journal.pone.0054605

PMCID:: PMC3558508

Abstract Article PDF–2.5M

Select item 349272515.

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

Estela Area-Gomez, Maria del Carmen Lara Castillo, Marc D Tambini, Cristina Guardia-Laguarta, Ad J C de Groof, Moneek Madra, Junichi Ikenouchi, Masato Umeda, Thomas D Bird, Stephen L Sturley, Eric A Schon

EMBO J. 2012 Nov 5; 31(21): 4106–4123. Published online 2012 Aug 14. doi: 10.1038/emboj.2012.202

PMCID:: PMC3492725

Abstract Article PDF–3.3M

Select item 338209816.

The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice

Ruben Vidal, Neeraja Sammeta, Holly J. Garringer, Kumar Sambamurti, Leticia Miravalle, Bruce T. Lamb, Bernardino Ghetti

FASEB J. 2012 Jul; 26(7): 2899–2910. doi: 10.1096/fj.12-205542

PMCID:: PMC3382098

Abstract Article

Select item 317150017.

Comparison of genome-wide gene expression in suture- and alkali burn-induced murine corneal neovascularization

Changkai Jia, Wei Zhu, Shengwei Ren, Haijie Xi, Siyuan Li, Yiqiang Wang

Mol Vis. 2011; 17: 2386–2399. Published online 2011 Sep 2.

PMCID:: PMC3171500

Abstract Article PDF–1.8M

Select item 284893018.

The selective β₁-adrenoceptor antagonist nebivolol is a potential oestrogen receptor agonist with neuroprotective abilities

D Manthey, M Gamerdinger, C Behl

Br J Pharmacol. 2010 Mar; 159(6): 1264–1273. Published online 2010 Feb 1. doi: 10.1111/j.1476-5381.2009.00610.x

PMCID:: PMC2848930

Abstract Article PDF–482K

Select item 243090819.

Notch-Deficient Skin Induces a Lethal Systemic B-Lymphoproliferative Disorder by Secreting TSLP, a Sentinel for Epidermal Integrity

Shadmehr Demehri, Zhenyi Liu, Jonghyeob Lee, Meei-Hua Lin, Seth D Crosby, Christopher J Roberts, Perry W Grigsby, Jeffrey H Miner, Andrew G Farr, Raphael Kopan

PLoS Biol. 2008 May; 6(5): e123. Published online 2008 May 27. doi: 10.1371/journal.pbio.0060123