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Select item 63603521.

Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1–Mediated Cholesterol Removal

Aicha Saadane, Natalia Mast, George Trichonas, Dibyendu Chakraborty, Sandra Hammer, Julia V. Busik, Maria B. Grant, Irina A. Pikuleva

Am J Pathol. 2019 Feb; 189(2): 405–425. doi: 10.1016/j.ajpath.2018.10.013

PMCID:: PMC6360352

Abstract Article

Select item 63271532.

Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1−/− mouse brain and plasma

William J. Griffiths, Peter J. Crick, Anna Meljon, Spyridon Theofilopoulos, Jonas Abdel-Khalik, Eylan Yutuc, Josie E. Parker, Diane E. Kelly, Steven L. Kelly, Ernest Arenas, Yuqin Wang

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Feb; 1864(2): 191–211. doi: 10.1016/j.bbalip.2018.11.006

PMCID:: PMC6327153

Abstract Article

Select item 57841763.

Sterol 27-hydroxylase gene dosage and the antiatherosclerotic effect of Rifampicin in mice

Line Zurkinden, Dmitri Sviridov, Bruno Vogt, Geneviève Escher

Biosci Rep. 2018 Feb 28; 38(1): BSR20171162. Prepublished online 2017 Nov 30. Published online 2018 Jan 25. doi: 10.1042/BSR20171162

PMCID:: PMC5784176

Abstract Article PDF–2.8M

Select item 56464194.

Distinct oxysterol requirements for positioning naïve and activated dendritic cells in the spleen

Erick Lu, Eric V. Dang, Jeffrey G. McDonald, Jason G. Cyster

Sci Immunol. Author manuscript; available in PMC 2017 Oct 18.

Published in final edited form as: Sci Immunol. 2017 Apr 7; 2(10): eaal5237. doi: 10.1126/sciimmunol.aal5237

PMCID:: PMC5646419

Abstract Article PDF–3.6M

Select item 56368795.

The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells

Amy E. Baek, Yen-Rei A. Yu, Sisi He, Suzanne E. Wardell, Ching-Yi Chang, Sanghoon Kwon, Ruchita V. Pillai, Hannah B. McDowell, J. Will Thompson, Laura G. Dubois, Patrick M. Sullivan, Jongsook K. Kemper, Michael D. Gunn, Donald P. McDonnell, Erik R. Nelson

Nat Commun. 2017; 8: 864. Published online 2017 Oct 11. doi: 10.1038/s41467-017-00910-z

PMCID:: PMC5636879

Abstract Article PDF–672K

Select item 56335886.

Metabolomic and transcriptomic profiling of hepatocellular carcinomas in Hras12V transgenic mice

Tingting Fan, Zhuona Rong, Jianyi Dong, Juan Li, Kangwei Wang, Xinxin Wang, Huiling Li, Jun Chen, Fujin Wang, Jingyu Wang, Aiguo Wang

Cancer Med. 2017 Oct; 6(10): 2370–2384. Published online 2017 Sep 21. doi: 10.1002/cam4.1177

PMCID:: PMC5633588

Abstract Article PDF–721K

Select item 53777767.

Berberine-induced Inactivation of Signal Transducer and Activator of Transcription 5 Signaling Promotes Male-specific Expression of a Bile Acid Uptake Transporter

Pengli Bu, Yuan Le, Yue Zhang, Youcai Zhang, Xingguo Cheng

J Biol Chem. 2017 Mar 17; 292(11): 4602–4613. Published online 2017 Feb 1. doi: 10.1074/jbc.M116.757567

PMCID:: PMC5377776

Abstract Article PDF–2.9M

Select item 47609248.

Lack of endogenous cholecystokinin promotes cholelithogenesis in mice

Helen H. Wang, Min Liu, Piero Portincasa, Patrick Tso, David Q.-H. Wang

Neurogastroenterol Motil. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Neurogastroenterol Motil. 2016 Mar; 28(3): 364–375. Published online 2015 Nov 25. doi: 10.1111/nmo.12734

PMCID:: PMC4760924

Abstract Article PDF–1.3M

Select item 47010419.

The deletion of the estrogen receptor α gene reduces susceptibility to estrogen-induced cholesterol cholelithiasis in female mice

Ornella de Bari, Helen H. Wang, Piero Portincasa, Min Liu, David Q.-H. Wang

Biochim Biophys Acta. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Biochim Biophys Acta. 2015 Oct; 1852(10 0 0): 2161–2169. Published online 2015 Jul 30. doi: 10.1016/j.bbadis.2015.07.020

PMCID:: PMC4701041

Abstract Article PDF–1.7M

Select item 444972410.

Mutations in the Bile Acid Biosynthetic Enzyme Sterol 27-Hydroxylase Underlie Cerebrotendinous Xanthomatosis

James J. Cali, Chih-Lin Hsieh, Uta Francke, David W. Russell

J Biol Chem. Author manuscript; available in PMC 2015 May 30.

Published in final edited form as: J Biol Chem. 1991 Apr 25; 266(12): 7779–7783.

PMCID:: PMC4449724

Abstract Article PDF–579K

Select item 402926611.

Lack of P2Y₁₃ in mice fed a high cholesterol diet results in decreased hepatic cholesterol content, biliary lipid secretion and reverse cholesterol transport

Laeticia Lichtenstein, Nizar Serhan, Wijtske Annema, Guillaume Combes, Bernard Robaye, Jean-Marie Boeynaems, Bertrand Perret, Uwe J F Tietge, Muriel Laffargue, Laurent O Martinez

Nutr Metab (Lond) 2013; 10: 67. Published online 2013 Nov 6. doi: 10.1186/1743-7075-10-67

PMCID:: PMC4029266

Abstract Article PDF–338K

Select item 398990012.

Sustained and Selective Suppression of Intestinal Cholesterol Synthesis by Ro 48-8071, an Inhibitor of 2,3-Oxidosqualene:Lanosterol Cyclase, in the BALB/c Mouse

Jen-Chieh Chuang, Mark A. Valasek, Adam M. Lopez, Kenneth S. Posey, Joyce J. Repa, Stephen D. Turley

Biochem Pharmacol. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Biochem Pharmacol. 2014 Apr 1; 88(3): 351–363. Published online 2014 Jan 31. doi: 10.1016/j.bcp.2014.01.031

PMCID:: PMC3989900

Abstract Article PDF–5.2M

Select item 340457113.

Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1^−/− mice fed low levels of cholic acid

Ryan D. Jones, Joyce J. Repa, David W. Russell, John M. Dietschy, Stephen D. Turley

Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15; 303(2): G263–G274. Published online 2012 May 24. doi: 10.1152/ajpgi.00111.2012

PMCID:: PMC3404571

Abstract Article

Select item 337274714.

Delayed activation of host innate immune pathways in streptozotocin-induced diabetic hosts leads to more severe disease during infection with Burkholderia pseudomallei

Chui-Yoke Chin, Denise M Monack, Sheila Nathan

Immunology. 2012 Apr; 135(4): 312–332. doi: 10.1111/j.1365-2567.2011.03544.x

PMCID:: PMC3372747

Abstract Article PDF–630K

Select item 316588915.

Synthesis of Hydroxylated Sterols in Transgenic Arabidopsis Plants Alters Growth and Steroid Metabolism

Lisa Beste, Nurun Nahar, Kerstin Dalman, Shozo Fujioka, Lisbeth Jonsson, Paresh C. Dutta, Folke Sitbon

Plant Physiol. 2011 Sep; 157(1): 426–440. Published online 2011 Jul 11. doi: 10.1104/pp.111.171199

PMCID:: PMC3165889

Abstract Article PDF–876K

Select item 313701616.

Cholesterol 25-hydroxylation activity of CYP3A

Akira Honda, Teruo Miyazaki, Tadashi Ikegami, Junichi Iwamoto, Tomomi Maeda, Takeshi Hirayama, Yoshifumi Saito, Tamio Teramoto, Yasushi Matsuzaki

J Lipid Res. 2011 Aug; 52(8): 1509–1516. doi: 10.1194/jlr.M014084

PMCID:: PMC3137016

Abstract Article PDF–773K

Select item 295469317.

Intermittent Hypoxia Mobilizes Bone Marrow-Derived Very Small Embryonic-Like Stem Cells and Activates Developmental Transcriptional Programs in Mice

Sina A. Gharib, Ehab A. Dayyat, Abdelnaby Khalyfa, Jinkwan Kim, Heather B. Clair, Magdalena Kucia, David Gozal

Sleep. 2010 Nov 1; 33(11): 1439–1446. doi: 10.1093/sleep/33.11.1439

PMCID:: PMC2954693

Abstract Article PDF–1.7M

Select item 286608218.

Marked variability in hepatic expression of cytochromes CYP7A1 and CYP27A1 as compared to cerebral CYP46A1. Lessons from a dietary study with omega 3 fatty acids in hamsters

Natalia Mast, Marjan Shafaati, Wahiduz Zaman, Wenchao Zheng, Deborah Prusak, Thomas Wood, G. A. S. Ansari, Anita Lövgren-Sandblom, Maria Olin, Ingemar Bjorkhem, Irina Pikuleva

Biochim Biophys Acta. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Biochim Biophys Acta. 2010 Jun; 1801(6): 674–681. Published online 2010 Mar 16. doi: 10.1016/j.bbalip.2010.03.005

PMCID:: PMC2866082

Abstract Article PDF–471K

Select item 285988819.

Gene expression profiling following short-term and long-term morphine exposure in mice uncovers genes involved in food intake

A. Anghel, C. A. M. Jamieson, X. Ren, J. Young, R. Porche, E. Ozigbo, D. E. Ghods, M. L. Lee, Y. Liu, K. Lutfy, T. C. Friedman

Neuroscience. Author manuscript; available in PMC 2011 May 5.

Published in final edited form as: Neuroscience. 2010 May 5; 167(2): 554–566. Published online 2010 Feb 6. doi: 10.1016/j.neuroscience.2010.01.043

PMCID:: PMC2859888

Abstract Article PDF–979K

Select item 285857820.

Gene Expression Profiling Reveals Early Cellular Responses to Intracellular Magnetic Labeling with Superparamagnetic Iron Oxide Nanoparticles

Dorota A. Kedziorek, Naser Muja, Piotr Walczak, Jesus Ruiz-Cabello, Assaf A. Gilad, Chunfa C. Jie, Jeff W. M. Bulte

Magn Reson Med. Author manuscript; available in PMC 2010 Apr 22.

Published in final edited form as: Magn Reson Med. 2010 Apr; 63(4): 1031–1043. doi: 10.1002/mrm.22290

PMCID:: PMC2858578

Abstract Article PDF–1.7M

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