PMC Links for Gene (Select 9869) - PMC

Gabriel K. Griffin, Jingyi Wu, Arvin Iracheta-Vellve, James C. Patti, Jeffrey Hsu, Thomas Davis, Deborah Dele-Oni, Peter P. Du, Aya Halawi, Jeffrey J. Ishizuka, Sarah Kim, Susan Klaeger, Nelson H. Knudsen, Brian C. Miller, Tung Nguyen, Kira Olander, Malvina Papanastasiou, Suzanna Rachimi, Emily J. Robitschek, Emily M. Schneider, Mitchell Yeary, Margaret D. Zimmer, Jacob D. Jaffe, Steven A. Carr, John G. Doench, W. Nicholas Haining, Kathleen B. Yates, Robert T. Manguso, Bradley E. Bernstein

Nature. Author manuscript; available in PMC 2022 Jun 4.

Published in final edited form as: Nature. 2021 Jul; 595(7866): 309–314. Published online 2021 May 5. doi: 10.1038/s41586-021-03520-4

PMCID:: PMC9166167

Abstract Article PDF–4.6M

Select item 90714015.

SETDB1 fuels the lung cancer phenotype by modulating epigenome, 3D genome organization and chromatin mechanical properties

Vlada V Zakharova, Mikhail D Magnitov, Laurence Del Maestro, Sergey V Ulianov, Alexandros Glentis, Burhan Uyanik, Alice Williart, Anna Karpukhina, Oleg Demidov, Veronique Joliot, Yegor S Vassetzky, René-Marc Mège, Matthieu Piel, Sergey V Razin, Slimane Ait-Si-Ali

Nucleic Acids Res. 2022 May 6; 50(8): 4389–4413. Published online 2022 Apr 26. doi: 10.1093/nar/gkac234

PMCID:: PMC9071401

Abstract Article PDF–10M

Select item 89675826.

Increased Expression of SETDB1 Predicts Poor Prognosis in Multiple Myeloma

Jing Xiang, Xiaotong Chen, Mengping Chen, Jian Hou

Biomed Res Int. 2022; 2022: 3307873. Published online 2022 Mar 23. doi: 10.1155/2022/3307873

PMCID:: PMC8967582

Abstract Article PDF–2.2M

Select item 87614527.

Expression of SET domain bifurcated histone lysine methyltransferase 1 and its clinical prognostic significance in hepatocellular carcinoma

Chunnian Wang, Zhaoxia Xia, Zheng Li, Fusang Ye, Shengqiang Ji, Changjiang Lu, Huizhi Zhang

J Clin Lab Anal. 2022 Jan; 36(1): e24090. Published online 2021 Nov 29. doi: 10.1002/jcla.24090

PMCID:: PMC8761452

Abstract Article PDF–1.5M

Select item 73544718.

SETDB1-Mediated Silencing of Retroelements

Kei Fukuda, Yoichi Shinkai

Viruses. 2020 Jun; 12(6): 596. Published online 2020 May 30. doi: 10.3390/v12060596

PMCID:: PMC7354471

Abstract Article PDF–1.2M

Select item 72144659.

SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression

Nan Cao, Yali Yu, Hua Zhu, Meng Chen, Ping Chen, Mingxing Zhuo, Yujuan Mao, Lianyun Li, Qiu Zhao, Min Wu, Mei Ye

Cell Death Dis. 2020 May; 11(5): 351. Published online 2020 May 11. doi: 10.1038/s41419-020-2561-6

PMCID:: PMC7214465

Abstract Article PDF–5.1M

Select item 719195710.

High SET Domain Bifurcated 1 (SETDB1) Expression Predicts Poor Prognosis in Breast Carcinoma

Zhaoping Zhou, Baojin Wu, Xinjie Tang, Wenlin Yang, Qiang Zou, Hongying Wang

Med Sci Monit. 2020; 26: e922982-1–e922982-11. Prepublished online 2020 Apr 14. Published online 2020 Apr 19. doi: 10.12659/MSM.922982

PMCID:: PMC7191957

Abstract Article PDF–3.0M

Select item 618051511.

Knockdown of SETDB1 inhibits breast cancer progression by miR-381-3p-related regulation

Milu Wu, Baohua Fan, Qijing Guo, Yan Li, Rong Chen, Nannan Lv, Yinzhuo Diao, Yushuang Luo

Biol Res. 2018; 51: 39. Published online 2018 Oct 11. doi: 10.1186/s40659-018-0189-0

PMCID:: PMC6180515

Abstract Article PDF–4.4M

Select item 572712712.

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1

Renata Z. Jurkowska, Su Qin, Goran Kungulovski, Wolfram Tempel, Yanli Liu, Pavel Bashtrykov, Judith Stiefelmaier, Tomasz P. Jurkowski, Srikanth Kudithipudi, Sara Weirich, Raluca Tamas, Hong Wu, Ludmila Dombrovski, Peter Loppnau, Richard Reinhardt, Jinrong Min, Albert Jeltsch

Nat Commun. 2017; 8: 2057. Published online 2017 Dec 12. doi: 10.1038/s41467-017-02259-9

PMCID:: PMC5727127

Abstract Article PDF–5.7M

Select item 567488313.

Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia

Trinna L. Cuellar, Anna-Maria Herzner, Xiaotian Zhang, Yogesh Goyal, Colin Watanabe, Brad A. Friedman, Vasantharajan Janakiraman, Steffen Durinck, Jeremy Stinson, David Arnott, Tommy K. Cheung, Subhra Chaudhuri, Zora Modrusan, Jonas Martin Doerr, Marie Classon, Benjamin Haley

J Cell Biol. 2017 Nov 6; 216(11): 3535–3549. doi: 10.1083/jcb.201612160

PMCID:: PMC5674883

Abstract Article PDF–2.1M

Select item 538280814.

Chromosomal Microarray Analysis in Clinical Evaluation of Neurodevelopmental Disorders-Reporting a Novel Deletion of SETDB1 and Illustration of Counseling Challenge

Qiong Xu, Jennifer Goldstein, Ping Wang, Inder K. Gadi, Heather Labreche, Catherine Rehder, Wei-Ping Wang, Allyn McConkie, Xiu Xu, Yong-hui Jiang

Pediatr Res. Author manuscript; available in PMC 2017 Apr 6.

Published in final edited form as: Pediatr Res. 2016 Sep; 80(3): 371–381. Published online 2016 Apr 27. doi: 10.1038/pr.2016.101

PMCID:: PMC5382808

Abstract Article PDF–1.1M

Select item 508795215.

Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity

Kenji Ishimoto, Natsuko Kawamata, Yoshie Uchihara, Moeka Okubo, Reiko Fujimoto, Eiko Gotoh, Keisuke Kakinouchi, Eiichi Mizohata, Nobumasa Hino, Yoshiaki Okada, Yasuhiro Mochizuki, Toshiya Tanaka, Takao Hamakubo, Juro Sakai, Tatsuhiko Kodama, Tsuyoshi Inoue, Keisuke Tachibana, Takefumi Doi

PLoS One. 2016; 11(10): e0165766. Published online 2016 Oct 31. doi: 10.1371/journal.pone.0165766

PMCID:: PMC5087952

Abstract Article PDF–3.3M

Select item 488499516.

Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas

Hio Chung Kang, Hong Kwan Kim, Sharon Lee, Pedro Mendez, James Wansoo Kim, Gavitt Woodard, Jun-Hee Yoon, Kuang-Yu Jen, Li Tai Fang, Kirk Jones, David M. Jablons, Il-Jin Kim

Oncotarget. 2016 Feb 16; 7(7): 8321–8331. Published online 2016 Jan 27. doi: 10.18632/oncotarget.7032

PMCID:: PMC4884995

Abstract Article PDF–3.8M

Select item 448169117.

Reactivation of maternal SNORD116 cluster via SETDB1 knockdown in Prader-Willi syndrome iPSCs

Estela Cruvinel, Tara Budinetz, Noelle Germain, Stormy Chamberlain, Marc Lalande, Kristen Martins-Taylor

Hum Mol Genet. 2014 Sep 1; 23(17): 4674–4685. Published online 2014 Apr 23. doi: 10.1093/hmg/ddu187

PMCID:: PMC4481691

Abstract Article PDF–905K

Select item 440031218.

Setdb1 Is Required for Myogenic Differentiation of C2C12 Myoblast Cells via Maintenance of MyoD Expression

Young Joon Song, Jang Hyun Choi, Hansol Lee

Mol Cells. 2015 Apr; 38(4): 362–372. Published online 2015 Feb 25. doi: 10.14348/molcells.2015.2291

PMCID:: PMC4400312

Abstract Article PDF–1.9M

Select item 433319719.

SETDB1 accelerates tumorigenesis by regulating WNT signaling pathway

Qiao-Yang Sun, Ling-Wen Ding, Jin-Fen Xiao, Wenwen Chien, Su-Lin Lim, Norimichi Hattori, Lee Goodglick, David Chia, Vei Mah, Mohammad Alavi, Sara R. Kim, Ngan B. Doan, Jonathan W. Said, Xin-Yi Loh, Liang Xu, Li-Zhen Liu, Henry Yang, Takahide Hayano, Shuo Shi, Dong Xie, De-Chen Lin, H. Phillip Koeffler

J Pathol. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: J Pathol. 2015 Mar; 235(4): 559–570. Published online 2014 Dec 18. doi: 10.1002/path.4482

PMCID:: PMC4333197

Abstract Article PDF–2.3M

Select item 334854520.

The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma

Craig J. Ceol, Yariv Houvras, Judit Jane-Valbuena, Steve Bilodeau, David A. Orlando, Valentine Battisti, Lauriane Fritsch, William M. Lin, Travis J. Hollmann, Fabrizio Ferré, Caitlin Bourque, Christopher J. Burke, Laura Turner, Audrey Uong, Laura A. Johnson, Rameen Beroukhim, Craig H. Mermel, Massimo Loda, Slimane Ait-Si-Ali, Levi A. Garraway, Richard A. Young, Leonard I. Zon

Nature. Author manuscript; available in PMC 2012 May 9.

Published in final edited form as: Nature. 2011 Mar 24; 471(7339): 513–517. doi: 10.1038/nature09806

PMCID:: PMC3348545

Abstract Article PDF–941K

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PMC Links for Gene (Select 9869) (124)
PMC
Mus musculus Zn-15 transcription factor (Zfp-15) mRNA, complete cds
Mus musculus Zn-15 transcription factor (Zfp-15) mRNA, complete cds
gi|4102928|gb|AF017806.1|

Nucleotide
PREDICTED: Homo sapiens SET domain bifurcated histone lysine methyltransferase 1...
PREDICTED: Homo sapiens SET domain bifurcated histone lysine methyltransferase 1 (SETDB1), transcript variant X6, mRNA
gi|2462515957|ref|XM_054339880.1|

Nucleotide
histone-lysine N-methyltransferase SETDB1 isoform X4 [Homo sapiens]
histone-lysine N-methyltransferase SETDB1 isoform X4 [Homo sapiens]
gi|2462515958|ref|XP_054195855.1|

Protein
PREDICTED: Homo sapiens SET domain bifurcated histone lysine methyltransferase 1...
PREDICTED: Homo sapiens SET domain bifurcated histone lysine methyltransferase 1 (SETDB1), transcript variant X4, mRNA
gi|2217272728|ref|XM_047435582.1|

Nucleotide

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