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Items: 1 to 20 of 48

1.
ARHGEF11 promotes proliferation and epithelial-mesenchymal transition of hepatocellular carcinoma through activation of β-catenin pathway
Jinpeng Du, Zexin Zhu, Lin Xu, Xing Chen, Xuefeng Li, Tian Lan, Wei Li, Kefei Yuan, Yong Zeng
Aging (Albany NY) 2020 Oct 31; 12(20): 20235–20253. Published online 2020 Oct 29. doi: 10.18632/aging.103772
PMCID:
PMC7655160
AbstractArticlePDF–3.2M
2.
Loss of ARHGEF1 causes a human primary antibody deficiency
Amine Bouafia, Sébastien Lofek, Julie Bruneau, Loïc Chentout, Hicham Lamrini, Amélie Trinquand, Marie-Céline Deau, Lucie Heurtier, Véronique Meignin, Capucine Picard, Elizabeth Macintyre, Olivier Alibeu, Marc Bras, Thierry Jo Molina, Marina Cavazzana, Isabelle André-Schmutz, Anne Durandy, Alain Fischer, Eric Oksenhendler, Sven Kracker
J Clin Invest. 2019 Mar 1; 129(3): 1047–1060. Published online 2019 Feb 4. doi: 10.1172/JCI120572
PMCID:
PMC6391114
AbstractArticlePDF–12M
3.
The amino acid motif L/IIxxFE defines a novel actin-binding sequence in PDZ-RhoGEF
Jayashree Banerjee, Christopher C. Fischer, Philip B. Wedegaertner
Biochemistry. Author manuscript; available in PMC 2010 Aug 25.
Published in final edited form as: Biochemistry. 2009 Aug 25; 48(33): 8032–8043. doi: 10.1021/bi9010013
PMCID:
PMC2728795
AbstractArticlePDF–1.6M
4.
On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF
Meiying Zheng, Tomasz Cierpicki, Ko Momotani, Mykhaylo V Artamonov, Urszula Derewenda, John H Bushweller, Avril V Somlyo, Zygmunt S Derewenda
BMC Struct Biol. 2009; 9: 36. Published online 2009 May 21. doi: 10.1186/1472-6807-9-36
PMCID:
PMC2695464
AbstractArticlePDF–1.3M
5.
PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells
Kit Wong, Alexandra Van Keymeulen, Henry R. Bourne
J Cell Biol. 2007 Dec 17; 179(6): 1141–1148. doi: 10.1083/jcb.200706167
PMCID:
PMC2140022
AbstractArticlePDF–1.6M
6.
Identification of a Novel Sequence in PDZ-RhoGEF That Mediates Interaction with the Actin Cytoskeleton
Jayashree Banerjee, Philip B. Wedegaertner
Mol Biol Cell. 2004 Apr; 15(4): 1760–1775. doi: 10.1091/mbc.E03-07-0527
PMCID:
PMC379273
AbstractArticlePDF–1022K
7.
PDZ-RhoGEF Is a Signaling Effector for TROY-Induced Glioblastoma Cell Invasion and Survival
Zonghui Ding, Harshil Dhruv, Aneta Kwiatkowska-Piwowarczyk, Rosamaria Ruggieri, Jean Kloss, Marc Symons, Patrick Pirrotte, Jennifer M. Eschbacher, Nhan L. Tran, Joseph C. Loftus
Neoplasia. 2018 Oct; 20(10): 1045–1058. Published online 2018 Sep 13. doi: 10.1016/j.neo.2018.08.008
PMCID:
PMC6140379
AbstractArticlePDF–999K
8.
PAK4 suppresses PDZ-RhoGEF activity to drive invadopodia maturation in melanoma cells
Nicole S. Nicholas, Aikaterini Pipili, Michaela S. Lesjak, Simon M. Ameer, Jenny L. C. Geh, Ciaran Healy, Alistair D. MacKenzie Ross, Maddy Parsons, Frank O. Nestle, Katie E. Lacy, Claire M. Wells
Oncotarget. 2016 Oct 25; 7(43): 70881–70897. Published online 2016 Sep 27. doi: 10.18632/oncotarget.12282
PMCID:
PMC5342596
AbstractArticlePDF–8.9M
9.
Regulated Localization Is Sufficient for Hormonal Control of Regulator of G Protein Signaling Homology Rho Guanine Nucleotide Exchange Factors (RH-RhoGEFs)
Angela M. Carter, Stephen Gutowski, Paul C. Sternweis
J Biol Chem. 2014 Jul 11; 289(28): 19737–19746. Published online 2014 May 22. doi: 10.1074/jbc.M114.564930
PMCID:
PMC4094083
AbstractArticlePDF–1.8M
10.
Insights into the Molecular Activation Mechanism of the RhoA-specific Guanine Nucleotide Exchange Factor, PDZRhoGEF
Jakub A. Bielnicki, Alexander V. Shkumatov, Urszula Derewenda, Avril V. Somlyo, Dmitri I. Svergun, Zygmunt S. Derewenda
J Biol Chem. 2011 Oct 7; 286(40): 35163–35175. Published online 2011 Aug 4. doi: 10.1074/jbc.M111.270918
PMCID:
PMC3186380
AbstractArticlePDF–3.6M
11.
Gαs directly drives PDZ-RhoGEF signaling to Cdc42
Alejandro Castillo-Kauil, Irving García-Jiménez, Rodolfo Daniel Cervantes-Villagrana, Sendi Rafael Adame-García, Yarely Mabell Beltrán-Navarro, J. Silvio Gutkind, Guadalupe Reyes-Cruz, José Vázquez-Prado
J Biol Chem. 2020 Dec 11; 295(50): 16920–16928. Published online 2020 Oct 6. doi: 10.1074/jbc.AC120.015204
PMCID:
PMC7863908
AbstractArticlePDF–3.1M
12.
Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ–RhoGEF
Heath G. Pascoe, Stephen Gutowski, Hua Chen, Chad A. Brautigam, Zhe Chen, Paul C. Sternweis, Xuewu Zhang
Proc Natl Acad Sci U S A. 2015 Dec 1; 112(48): 14852–14857. Published online 2015 Nov 16. doi: 10.1073/pnas.1508931112
PMCID:
PMC4672773
AbstractArticlePDF–1.9M
13.
PYK2/PDZ-RhoGEF links Ca2+ signaling to RhoA
Zhekang Ying, Fernanda R.C. Giachini, Rita C. Tostes, R. Clinton Webb
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Mar 3.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Oct; 29(10): 1657–1663. doi: 10.1161/ATVBAHA.109.190892
PMCID:
PMC3939713
AbstractArticlePDF–1.4M
14.
Mechanistic Insights into Specificity, Activity, and Regulatory Elements of the Regulator of G-protein Signaling (RGS)-containing Rho-specific Guanine Nucleotide Exchange Factors (GEFs) p115, PDZ-RhoGEF (PRG), and Leukemia-associated RhoGEF (LARG)
Mamta Jaiswal, Lothar Gremer, Radovan Dvorsky, Lars Christian Haeusler, Ion C. Cirstea, Katharina Uhlenbrock, Mohammad Reza Ahmadian
J Biol Chem. 2011 May 20; 286(20): 18202–18212. Published online 2011 Mar 28. doi: 10.1074/jbc.M111.226431
PMCID:
PMC3093892
AbstractArticlePDF–2.2M
15.
HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway
Xiaoyu Jiang, Xiaoqing Lu, George McNamara, Xiaofei Liu, Elena Cubedo, Kristopher A. Sarosiek, Isidro Sánchez-García, David M. Helfman, Izidore S. Lossos
Blood. 2010 Dec 9; 116(24): 5217–5227. Prepublished online 2010 Sep 15. doi: 10.1182/blood-2010-04-281568
PMCID:
PMC3012539
AbstractArticle
16.
Gα12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
Nobuchika Suzuki, Susumu Nakamura, Hiroyuki Mano, Tohru Kozasa
Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2): 733–738. Published online 2003 Jan 6. doi: 10.1073/pnas.0234057100
PMCID:
PMC141065
AbstractArticlePDF–337K
17.
A bacterial effector targets host DH-PH domain RhoGEFs and antagonizes macrophage phagocytosis
Na Dong, Liping Liu, Feng Shao
EMBO J. 2010 Apr 21; 29(8): 1363–1376. Published online 2010 Mar 18. doi: 10.1038/emboj.2010.33
PMCID:
PMC2868573
AbstractArticlePDF–2.5M
18.
Agonist-induced Ca2+ Sensitization in Smooth Muscle: REDUNDANCY OF RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS (RhoGEFs) AND RESPONSE KINETICS, A CAGED COMPOUND STUDY
Mykhaylo V. Artamonov, Ko Momotani, Andra Stevenson, David R. Trentham, Urszula Derewenda, Zygmunt S. Derewenda, Paul W. Read, J. Silvio Gutkind, Avril V. Somlyo
J Biol Chem. 2013 Nov 22; 288(47): 34030–34040. Published online 2013 Oct 8. doi: 10.1074/jbc.M113.514596
PMCID:
PMC3837142
AbstractArticlePDF–1.8M
19.
Rewiring of RSK-PDZ interactome by linear motif phosphorylation
Gergő Gógl, Beáta Biri-Kovács, Fabien Durbesson, Pau Jane, Yves Nomine, Camille Kostmann, Viktória Bilics, Márton Simon, Attila Reményi, Renaud Vincentelli, Gilles Trave, László Nyitray
J Mol Biol. Author manuscript; available in PMC 2020 Mar 15.
Published in final edited form as: J Mol Biol. 2019 Mar 15; 431(6): 1234–1249. Published online 2019 Feb 3. doi: 10.1016/j.jmb.2019.01.038
PMCID:
PMC6424611
AbstractArticlePDF–2.6M
20.
DEPDC1B Coordinates De-adhesion Events and Cell-Cycle Progression at Mitosis
Stefano Marchesi, Francesca Montani, Gianluca Deflorian, Rocco D’Antuono, Alessandro Cuomo, Serena Bologna, Carmela Mazzoccoli, Tiziana Bonaldi, Pier Paolo Di Fiore, Francesco Nicassio
Dev Cell. 2014 Nov 24; 31(4): 420–433. doi: 10.1016/j.devcel.2014.09.009
PMCID:
PMC4250264
AbstractArticle

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