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Items: 1 to 20 of 101

1.
SETD1A drives stemness by reprogramming the epigenetic landscape in hepatocellular carcinoma stem cells
Jianxu Chen, Zhijie Xu, Hongbin Huang, Yao Tang, Hong Shan, Fei Xiao
JCI Insight. 2023 Sep 22; 8(18): e168375. Published online 2023 Sep 22. doi: 10.1172/jci.insight.168375
PMCID:
PMC10561725
AbstractArticlePDF–11M
2.
SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
Takayuki Hoshii, Sarah Perlee, Sota Kikuchi, Bahityar Rahmutulla, Masaki Fukuyo, Takeshi Masuda, Sumio Ohtsuki, Tomoyoshi Soga, Behnam Nabet, Atsushi Kaneda
Cell Rep. Author manuscript; available in PMC 2022 Dec 21.
Published in final edited form as: Cell Rep. 2022 Nov 29; 41(9): 111727. doi: 10.1016/j.celrep.2022.111727
PMCID:
PMC9771694
AbstractArticlePDF–2.7M
3.
Histone methyltransferase SETD1A participates in lung cancer progression
Mei Du, Piping Gong, Yun Zhang, Yanguo Liu, Xiaozhen Liu, Feng Zhang, Xiuwen Wang
Thorac Cancer. 2021 Aug; 12(16): 2247–2257. Published online 2021 Jul 4. doi: 10.1111/1759-7714.14065
PMCID:
PMC8365002
AbstractArticlePDF–2.7M
4.
Knockdown of Histone Methyltransferase hSETD1A Inhibits Progression, Migration, and Invasion in Human Hepatocellular Carcinoma
Xin-sheng Cheng, Shi-bo Sun, Feng Zhong, Kun He, Jie Zhou
Oncol Res. 2016; 24(4): 239–245. Published online 2016 Aug 10. doi: 10.3727/096504016X14648701448011
PMCID:
PMC7838640
AbstractArticlePDF–4.9M
5.
Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
Shan Wang, Jon-Ruben van Rhijn, Ibrahim Akkouh, Naoki Kogo, Nadine Maas, Anna Bleeck, Irene Santisteban Ortiz, Elly Lewerissa, Ka Man Wu, Chantal Schoenmaker, Srdjan Djurovic, Hans van Bokhoven, Tjitske Kleefstra, Nael Nadif Kasri, Dirk Schubert
Cell Rep. Author manuscript; available in PMC 2024 Apr 2.
Published in final edited form as: Cell Rep. 2022 May 3; 39(5): 110790. doi: 10.1016/j.celrep.2022.110790
PMCID:
PMC7615788
AbstractArticlePDF–12M
6.
Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders
Tarjinder Singh, Mitja I Kurki, David Curtis, Shaun M Purcell, Lucy Crooks, Jeremy McRae, Jaana Suvisaari, Himanshu Chheda, Douglas Blackwood, Gerome Breen, Olli Pietiläinen, Sebastian S Gerety, Muhammad Ayub, Moira Blyth, Trevor Cole, David Collier, Eve L Coomber, Nick Craddock, Mark J Daly, John Danesh, Marta DiForti, Alison Foster, Nelson B Freimer, Daniel Geschwind, Mandy Johnstone, Shelagh Joss, Georg Kirov, Jarmo Körkkö, Outi Kuismin, Peter Holmans, Christina M Hultman, Conrad Iyegbe, Jouko Lönnqvist, Minna Männikkö, Steve A McCarroll, Peter McGuffin, Andrew M McIntosh, Andrew McQuillin, Jukka S Moilanen, Carmel Moore, Robin M Murray, Ruth Newbury-Ecob, Willem Ouwehand, Tiina Paunio, Elena Prigmore, Elliott Rees, David Roberts, Jennifer Sambrook, Pamela Sklar, David St Clair, Juha Veijola, James T R Walters, Hywel Williams, Swedish Schizophrenia Study, INTERVAL Study, DDD Study, UK10 K Consortium, Patrick F Sullivan, Matthew E Hurles, Michael C O’Donovan, Aarno Palotie, Michael J Owen, Jeffrey C Barrett
Nat Neurosci. Author manuscript; available in PMC 2019 Aug 10.
Published in final edited form as: Nat Neurosci. 2016 Apr 1; 19(4): 571–577. Published online 2016 Mar 14. doi: 10.1038/nn.4267
PMCID:
PMC6689268
AbstractArticlePDF–1.0M
7.
SETD1A protects from senescence through regulation of the mitotic gene expression program
Ken Tajima, Satoru Matsuda, Toshifumi Yae, Benjamin J. Drapkin, Robert Morris, Myriam Boukhali, Kira Niederhoffer, Valentine Comaills, Taronish Dubash, Linda Nieman, Hongshan Guo, Neelima K. C. Magnus, Nick Dyson, Toshihiro Shioda, Wilhelm Haas, Daniel A. Haber, Shyamala Maheswaran
Nat Commun. 2019; 10: 2854. Published online 2019 Jun 28. doi: 10.1038/s41467-019-10786-w
PMCID:
PMC6599037
AbstractArticlePDF–2.6M
8.
hSETD1A Regulates Wnt Target Genes and Controls Tumor Growth of Colorectal Cancer Cells
Tal Salz, Guangyao Li, Frederic Kaye, Lei Zhou, Yi Qiu, Suming Huang
Cancer Res. Author manuscript; available in PMC 2017 Jun 26.
Published in final edited form as: Cancer Res. 2014 Feb 1; 74(3): 775–786. Published online 2013 Nov 18. doi: 10.1158/0008-5472.CAN-13-1400
PMCID:
PMC5484530
AbstractArticlePDF–1.9M
9.
Loss-of-Function Variants in Schizophrenia Risk and SETD1A as a Candidate Susceptibility Gene
Atsushi Takata, Bin Xu, Iuliana Ionita-Laza, J. Louw Roos, Joseph A. Gogos, Maria Karayiorgou
Neuron. Author manuscript; available in PMC 2015 Apr 7.
Published in final edited form as: Neuron. 2014 May 21; 82(4): 773–780. doi: 10.1016/j.neuron.2014.04.043
PMCID:
PMC4387883
AbstractArticlePDF–431K
10.
In Vivo and In Vitro Characterization of the RNA Binding Capacity of SETD1A (KMT2F)
Harem Muhamad Amin, Beata Szabo, Rawan Abukhairan, Andras Zeke, József Kardos, Eva Schad, Agnes Tantos
Int J Mol Sci. 2023 Nov; 24(22): 16032. Published online 2023 Nov 7. doi: 10.3390/ijms242216032
PMCID:
PMC10671326
AbstractArticlePDF–5.2M
11.
Epigenotype–genotype–phenotype correlations in SETD1A and SETD2 chromatin disorders
Sunwoo Lee, Lara Menzies, Eleanor Hay, Eguzkine Ochoa, France Docquier, Fay Rodger, Charu Deshpande, Nicola C Foulds, Sébastien Jacquemont, Khadije Jizi, Henriette Kiep, Alison Kraus, Katharina Löhner, Patrick J Morrison, Bernt Popp, Ruth Richardson, Arie van Haeringen, Ezequiel Martin, Ana Toribio, Fudong Li, Wendy D Jones, Francis H Sansbury, Eamonn R Maher
Hum Mol Genet. 2023 Nov 15; 32(22): 3123–3134. Published online 2023 May 11. doi: 10.1093/hmg/ddad079
PMCID:
PMC10630252
AbstractArticlePDF–1.4M
12.
Histone methyltransferase SETD1A interacts with HIF1α to enhance glycolysis and promote cancer progression in gastric cancer
Jugang Wu, Hongjuan Chai, Xin Xu, Jiwei Yu, Yan Gu
Mol Oncol. 2020 Jun; 14(6): 1397–1409. Published online 2020 Apr 26. doi: 10.1002/1878-0261.12689
PMCID:
PMC7266269
AbstractArticlePDF–3.4M
13.
LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter
Hongyan Ni, Peiwei Chai, Jie Yu, Yue Xing, Shaoyun Wang, Jiayan Fan, Shengfang Ge, Yefei Wang, Renbing Jia, Xianqun Fan
Cell Death Dis. 2020 May; 11(5): 306. Published online 2020 May 4. doi: 10.1038/s41419-020-2524-y
PMCID:
PMC7198571
AbstractArticlePDF–11M
14.
De Novo and Inherited SETD1A Variants in Early-onset Epilepsy
Xiuya Yu, Lin Yang, Jin Li, Wanxing Li, Dongzhi Li, Ran Wang, Kai Wu, Wenhao Chen, Yi Zhang, Zilong Qiu, Wenhao Zhou
Neurosci Bull. 2019 Dec; 35(6): 1045–1057. Published online 2019 Jun 13. doi: 10.1007/s12264-019-00400-w
PMCID:
PMC6864154
AbstractArticlePDF–2.2M
15.
Aberrant expression of SETD1A promotes survival and migration of estrogen receptor α-positive breast cancer cells
Ming Li Jin, Young Woong Kim, Hong Lan Jin, Hoin Kang, Eun Kyung Lee, Michael R. Stallcup, Kwang Won Jeong
Int J Cancer. Author manuscript; available in PMC 2018 Dec 4.
Published in final edited form as: Int J Cancer. 2018 Dec 1; 143(11): 2871–2883. Published online 2018 Oct 4. doi: 10.1002/ijc.31853
PMCID:
PMC6278950
AbstractArticlePDF–937K
16.
Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2
Martin R. Higgs, Koichi Sato, John J. Reynolds, Shabana Begum, Rachel Bayley, Amalia Goula, Audrey Vernet, Karissa L. Paquin, David G. Skalnik, Wataru Kobayashi, Minoru Takata, Niall G. Howlett, Hitoshi Kurumizaka, Hiroshi Kimura, Grant S. Stewart
Mol Cell. 2018 Jul 5; 71(1): 25–41.e6. doi: 10.1016/j.molcel.2018.05.018
PMCID:
PMC6039718
AbstractArticle
17.
Increased Set1 binding at the promoter induces aberrant epigenetic alterations and up-regulates cyclic adenosine 5'-monophosphate response element modulator alpha in systemic lupus erythematosus
Qing Zhang, Shu Ding, Huilin Zhang, Hai Long, Haijing Wu, Ming Zhao, Vera Chan, Chak-Sing Lau, Qianjin Lu
Clin Epigenetics. 2016; 8: 126. Published online 2016 Nov 24. doi: 10.1186/s13148-016-0294-2
PMCID:
PMC5122196
AbstractArticlePDF–1.9M
18.
SETD1A induced miRNA network suppresses the p53 gene expression module
Toshifumi Yae, Ken Tajima, Shyamala Maheswaran
Cell Cycle. 2016; 15(4): 487–488. Published online 2016 Feb 11. doi: 10.1080/15384101.2015.1130572
PMCID:
PMC5056611
ArticlePDF–314K
19.
De Novo Synonymous Mutations in Regulatory Elements Contribute to the Genetic Etiology of Autism and Schizophrenia
Atsushi Takata, Iuliana Ionita-Laza, Joseph A. Gogos, Bin Xu, Maria Karayiorgou
Neuron. Author manuscript; available in PMC 2017 Mar 2.
Published in final edited form as: Neuron. 2016 Mar 2; 89(5): 940–947. doi: 10.1016/j.neuron.2016.02.024
PMCID:
PMC4793939
AbstractArticlePDF–479K
20.
SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes
Ken Tajima, Toshifumi Yae, Sarah Javaid, Oliver Tam, Valentine Comaills, Robert Morris, Ben S. Wittner, Mingzhu Liu, Amanda Engstrom, Fumiyuki Takahashi, Joshua C. Black, Sridhar Ramaswamy, Toshihiro Shioda, Molly Hammell, Daniel A. Haber, Johnathan R. Whetstine, Shyamala Maheswaran
Nat Commun. 2015; 6: 8257. Published online 2015 Sep 23. doi: 10.1038/ncomms9257
PMCID:
PMC4667427
AbstractArticlePDF–737K

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