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Select item 108051731.

Germline variation in RASAL2 may predict survival in patients with RAS‐activated colorectal cancer

Christopher Wills, Katie Watts, Timothy S. Maughan, David Fisher, Nada A. Al‐Tassan, Richard S. Houlston, Valentina Escott‐Price, Jeremy P. Cheadle

Genes Chromosomes Cancer. 2023 Jun; 62(6): 332–341. Published online 2023 Mar 8. doi: 10.1002/gcc.23133

PMCID:: PMC10805173

Abstract Article PDF–2.1M

Select item 92744912.

RASAL2 mediated the enhancement of YAP1/TIAM1 signaling promotes malignant phenotypes of pancreatic ductal adenocarcinoma

Yangyang Yue, Kaijie Wu, Weikun Qian, Zeen Zhu, Simei Zhang, Wunai Zhang, Weifan Zhang, Shuai Wu, Li Li, Zheng Wu, Qingyong Ma, Keping Xie, Zheng Wang

Int J Biol Sci. 2022; 18(10): 4245–4259. Published online 2022 Jun 27. doi: 10.7150/ijbs.72204

PMCID:: PMC9274491

Abstract Article PDF–3.2M

Select item 86323403.

PRKAA/AMPKα phosphorylation switches the role of RASAL2 from a suppressor to an activator of autophagy

Yong Bao, Christopher Qian, Meng-Yue Liu, Fei Jiang, Xiaoxiao Jiang, Huijuan Liu, Zhuqing Zhang, Fanghui Sun, Ningwei Fu, Zhaoyuan Hou, Ya Ke, Yan Li, Zhong-Ming Qian

Autophagy. 2021; 17(11): 3607–3621. Published online 2021 Feb 24. doi: 10.1080/15548627.2021.1886767

PMCID:: PMC8632340

Abstract Article PDF–13M

Select item 69213634.

Phosphorylated Rasal2 facilitates breast cancer progression

Xuan Wang, Christopher Qian, Yinlong Yang, Meng-Yue Liu, Ya Ke, Zhong-Ming Qian

EBioMedicine. 2019 Dec; 50: 144–155. Published online 2019 Nov 21. doi: 10.1016/j.ebiom.2019.11.019

Correction in:: EBioMedicine. 2020 Dec; 62: 103127.

Correction in:: EBioMedicine. 2021 Apr; 66: 103295.

PMCID:: PMC6921363

Abstract Article PDF–3.7M

Select item 61154595.

The expression and function of RASAL2 in renal cell carcinoma angiogenesis

Ke Hui, Yangyang Yue, Shiqi Wu, Yanan Gu, Bing Guan, Xinyang Wang, Jer-Tsong Hsieh, Luke S. Chang, Dalin He, Kaijie Wu

Cell Death Dis. 2018 Sep; 9(9): 881. Published online 2018 Aug 29. doi: 10.1038/s41419-018-0898-x

PMCID:: PMC6115459

Abstract Article PDF–2.9M

Select item 60570366.

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer

Yi Pan, Joanna Hung Man Tong, Raymond Wai Ming Lung, Wei Kang, Johnny Sheung Him Kwan, Wing Po Chak, Ka Yee Tin, Lau Ying Chung, Feng Wu, Simon Siu Man Ng, Tony Wing Chung Mak, Jun Yu, Kwok Wai Lo, Anthony Wing Hung Chan, Ka Fai To

Mol Cancer. 2018; 17: 102. Published online 2018 Jul 23. doi: 10.1186/s12943-018-0853-6

PMCID:: PMC6057036

Abstract Article PDF–6.8M

Select item 41961597.

RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasis

Yuting Huang, Meng Zhao, Haixu Xu, Ke Wang, Zheng Fu, Yuan Jiang, Zhi Yao

Oncotarget. 2014 Aug; 5(16): 6734–6745. Published online 2014 Jul 23. doi: 10.18632/oncotarget.2244

PMCID:: PMC4196159

Abstract Article PDF–3.7M

Select item 77514728.

miR-654-3p suppresses cell viability and promotes apoptosis by targeting RASAL2 in non-small-cell lung cancer

Jie Xiong, Shigang Xing, Zheng Dong, Lei Niu, Qinghua Xu, Yusheng Li, Pingyi Liu, Peixia Yang

Mol Med Rep. 2021 Feb; 23(2): 124. Published online 2020 Dec 8. doi: 10.3892/mmr.2020.11763

PMCID:: PMC7751472

Abstract Article PDF–1.9M

Select item 66177049.

IPO5 promotes the proliferation and tumourigenicity of colorectal cancer cells by mediating RASAL2 nuclear transportation

Wenjuan Zhang, Yanxia Lu, Xiaomin Li, Jianming Zhang, Weihao Lin, Wei Zhang, Lin Zheng, Xuenong Li

J Exp Clin Cancer Res. 2019; 38: 296. Published online 2019 Jul 9. doi: 10.1186/s13046-019-1290-0

PMCID:: PMC6617704

Abstract Article PDF–8.7M

Select item 646136110.

Loss of RasGAP tumor suppressors underlie the aggressive nature of luminal B breast cancers

Sarah Naomi Olsen, Ania Wronski, Zafira Castaño, Benjamin Dake, Clare Malone, Thomas De Raedt, Miriam Enos, Yoko S. DeRose, Wenhui Zhou, Stephanie Guerra, Massimo Loda, Alana Welm, Ann H. Partridge, Sandra S. McAllister, Charlotte Kuperwasser, Karen Cichowski

Cancer Discov. Author manuscript; available in PMC 2019 Apr 12.

Published in final edited form as: Cancer Discov. 2017 Feb; 7(2): 202–217. Published online 2016 Dec 14. doi: 10.1158/2159-8290.CD-16-0520

PMCID:: PMC6461361

Abstract Article PDF–2.8M

Select item 538650011.

RASAL2, a RAS GTPase-activating protein, inhibits stemness and epithelial–mesenchymal transition via MAPK/SOX2 pathway in bladder cancer

Ke Hui, Yang Gao, Jun Huang, Shan Xu, Bin Wang, Jin Zeng, Jinhai Fan, Xinyang Wang, Yangyang Yue, Shiqi Wu, Jer-Tsong Hsieh, Dalin He, Kaijie Wu

Cell Death Dis. 2017 Feb; 8(2): e2600. Published online 2017 Feb 9. doi: 10.1038/cddis.2017.9

PMCID:: PMC5386500

Abstract Article PDF–4.3M

Select item 489901412.

miR-136 suppresses tumor invasion and metastasis by targeting RASAL2 in triple-negative breast cancer

MEISI YAN, XIAOBO LI, DANDAN TONG, CHANGSONG HAN, RAN ZHAO, YAN HE, XIAOMING JIN

Oncol Rep. 2016 Jul; 36(1): 65–71. Published online 2016 Apr 25. doi: 10.3892/or.2016.4767

PMCID:: PMC4899014

Abstract Article PDF–647K

Select item 434896313.

RASAL2 activates RAC1 to promote triple-negative breast cancer progression

Min Feng, Yi Bao, Zhimei Li, Juntao Li, Min Gong, Stella Lam, Jinhua Wang, Diego M. Marzese, Nicholas Donovan, Ern Yu Tan, Dave S.B. Hoon, Qiang Yu

J Clin Invest. 2014 Dec 1; 124(12): 5291–5304. Published online 2014 Nov 10. doi: 10.1172/JCI76711

PMCID:: PMC4348963

Abstract Article PDF–6.6M

Select item 382233414.

The RasGAP Gene, RASAL2, is a Tumor and Metastasis Suppressor

Sara Koenig McLaughlin, Sarah Naomi Olsen, Benjamin Dake, Thomas De Raedt, Elgene Lim, Roderick Terry Bronson, Rameen Beroukhim, Kornelia Polyak, Myles Brown, Charlotte Kuperwasser, Karen Cichowski

Cancer Cell. Author manuscript; available in PMC 2014 Sep 9.

Published in final edited form as: Cancer Cell. 2013 Sep 9; 24(3): 10.1016/j.ccr.2013.08.004. doi: 10.1016/j.ccr.2013.08.004

PMCID:: PMC3822334

Abstract Article PDF–5.2M

Select item 336713115.

Genome-Wide Association Study of Antibody Response to Smallpox Vaccine

Inna G. Ovsyannikova, Richard B. Kennedy, Megan O'Byrne, Robert M. Jacobson, V. Shane Pankratz, Gregory A. Poland

Vaccine. Author manuscript; available in PMC 2013 Jun 13.

Published in final edited form as: Vaccine. 2012 Jun 13; 30(28): 4182–4189. Published online 2012 Apr 25. doi: 10.1016/j.vaccine.2012.04.055

PMCID:: PMC3367131

Abstract Article PDF–1.3M

Select item 689579316.

Characterization of HMGB1/2 Interactome in Prostate Cancer by Yeast Two Hybrid Approach: Potential Pathobiological Implications

Aida Barreiro-Alonso, María Cámara-Quílez, Martín Salamini-Montemurri, Mónica Lamas-Maceiras, Ángel Vizoso-Vázquez, Esther Rodríguez-Belmonte, María Quindós-Varela, Olaia Martínez-Iglesias, Angélica Figueroa, María-Esperanza Cerdán

Cancers (Basel) 2019 Nov; 11(11): 1729. Published online 2019 Nov 5. doi: 10.3390/cancers11111729

PMCID:: PMC6895793

Abstract Article PDF–3.1M

Select item 260067017.

Hepatitis C virus infection protein network

B de Chassey, V Navratil, L Tafforeau, M S Hiet, A Aublin-Gex, S Agaugué, G Meiffren, F Pradezynski, B F Faria, T Chantier, M Le Breton, J Pellet, N Davoust, P E Mangeot, A Chaboud, F Penin, Y Jacob, P O Vidalain, M Vidal, P André, C Rabourdin-Combe, V Lotteau

Mol Syst Biol. 2008; 4: 230. Published online 2008 Nov 4. doi: 10.1038/msb.2008.66