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Select item 43822681.

Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor

Geun Hyang Kim, Gyun-Sik Oh, Jin Yoon, Gang Gu Lee, Ki-Up Lee, Seung-Whan Kim

J Clin Invest. 2015 Jan 2; 125(1): 183–193. Published online 2014 Dec 1. doi: 10.1172/JCI73615

PMCID:: PMC4382268

Abstract Article PDF–2.4M

Select item 29789462.

Infantile Cerebral and Cerebellar Atrophy Is Associated with a Mutation in the MED17 Subunit of the Transcription Preinitiation Mediator Complex

Rami Kaufmann, Rachel Straussberg, Hanna Mandel, Aviva Fattal-Valevski, Bruria Ben-Zeev, Adi Naamati, Avraham Shaag, Shamir Zenvirt, Osnat Konen, Aviva Mimouni-Bloch, William B. Dobyns, Simon Edvardson, Ophry Pines, Orly Elpeleg

Am J Hum Genet. 2010 Nov 12; 87(5): 667–670. doi: 10.1016/j.ajhg.2010.09.016

PMCID:: PMC2978946

Abstract Article PDF–327K

Select item 81085083.

The cell polarity kinase Par1b/MARK2 activation selects specific NF-kB transcripts via phosphorylation of core mediator Med17/TRAP80

Anastasia Mashukova, Radia Forteza, Viraj N. Shah, Pedro J. Salas

Mol Biol Cell. 2021 Apr 15; 32(8): 690–702. doi: 10.1091/mbc.E20-10-0646

PMCID:: PMC8108508

Abstract Article PDF–3.7M

Select item 30236444.

Mediator and post-recruitment regulation of RNA polymerase II

Matthew T Knuesel, Dylan J Taatjes

Transcription. 2011 Jan-Feb; 2(1): 28–31. Published online 2010 Oct 17. doi: 10.4161/trns.2.1.13950

PMCID:: PMC3023644

Abstract Article PDF–140K

Select item 1515395.

Role of Metazoan Mediator Proteins in Interferon-Responsive Transcription

Joe F. Lau, Inna Nusinzon, Darya Burakov, Leonard P. Freedman, Curt M. Horvath

Mol Cell Biol. 2003 Jan; 23(2): 620–628. doi: 10.1128/MCB.23.2.620-628.2003

PMCID:: PMC151539

Abstract Article PDF–437K

Select item 16936926.

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220

Melanie Stumpf, Claudia Waskow, Marit Krötschel, Dominic van Essen, Patrick Rodriguez, Xiaoting Zhang, Boris Guyot, Robert G. Roeder, Tilman Borggrefe

Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49): 18504–18509. Published online 2006 Nov 28. doi: 10.1073/pnas.0604494103

Correction in:: Proc Natl Acad Sci U S A. 2007 Jan 23; 104(4): 1442.

PMCID:: PMC1693692

Abstract Article PDF–1.2M

Select item 37743657.

Mediator Complex Recruits Epigenetic Regulators via Its Two Cyclin-dependent Kinase Subunits to Repress Transcription of Immune Response Genes

Taiki Tsutsui, Rikiya Fukasawa, Kaori Shinmyouzu, Reiko Nakagawa, Kazuyuki Tobe, Aki Tanaka, Yoshiaki Ohkuma

J Biol Chem. 2013 Jul 19; 288(29): 20955–20965. Published online 2013 Jun 9. doi: 10.1074/jbc.M113.486746

PMCID:: PMC3774365

Abstract Article PDF–1.5M

Select item 1339608.

TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4

Sohail Malik, Annika E. Wallberg, Yun Kyoung Kang, Robert G. Roeder

Mol Cell Biol. 2002 Aug; 22(15): 5626–5637. doi: 10.1128/MCB.22.15.5626-5637.2002

PMCID:: PMC133960

Abstract Article PDF–330K

Select item 386709.

Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.

J D Fondell, H Ge, R G Roeder

Proc Natl Acad Sci U S A. 1996 Aug 6; 93(16): 8329–8333. doi: 10.1073/pnas.93.16.8329

PMCID:: PMC38670

Summary Page Browse PDF–1.5M

Select item 292028610.

CDK8 is a positive regulator of transcriptional elongation within the serum response network

Aaron J. Donner, Christopher C. Ebmeier, Dylan J. Taatjes, Joaquín M. Espinosa

Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Aug 11.

Published in final edited form as: Nat Struct Mol Biol. 2010 Feb; 17(2): 194–201. Published online 2010 Jan 24. doi: 10.1038/nsmb.1752

PMCID:: PMC2920286

Abstract Article PDF–2.1M

Select item 242313011.

MED1 Phosphorylation Promotes Its Association with Mediator: Implications for Nuclear Receptor Signaling

Madesh Belakavadi, Pradeep K. Pandey, Ravi Vijayvargia, Joseph D. Fondell

Mol Cell Biol. 2008 Jun; 28(12): 3932–3942. Published online 2008 Apr 7. doi: 10.1128/MCB.02191-07

PMCID:: PMC2423130

Abstract Article PDF–1.5M

Select item 29181412.

A novel docking site on Mediator is critical for activation by VP16 in mammalian cells

Gerhard Mittler, Thomas Stühler, Lisa Santolin, Thomas Uhlmann, Elisabeth Kremmer, F. Lottspeich, Lucia Berti, Michael Meisterernst

EMBO J. 2003 Dec 15; 22(24): 6494–6504. doi: 10.1093/emboj/cdg619

PMCID:: PMC291814

Abstract Article PDF–382K

Select item 239639513.

Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3

Krista D Meyer, Aaron J Donner, Matthew T Knuesel, Autumn G York, Joaquín M Espinosa, Dylan J Taatjes

EMBO J. 2008 May 21; 27(10): 1447–1457. Published online 2008 Apr 17. doi: 10.1038/emboj.2008.78

PMCID:: PMC2396395

Abstract Article PDF–303K

Select item 222328314.

STAGA Recruits Mediator to the MYC Oncoprotein To Stimulate Transcription and Cell Proliferation

Xiaohui Liu, Marina Vorontchikhina, Yuan-Liang Wang, Francesco Faiola, Ernest Martinez

Mol Cell Biol. 2008 Jan; 28(1): 108–121. Published online 2007 Oct 27. doi: 10.1128/MCB.01402-07

PMCID:: PMC2223283

Abstract Article PDF–664K

Select item 12491815.

Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase

Christopher S. Brower, Shigeo Sato, Chieri Tomomori-Sato, Takumi Kamura, Arnim Pause, Robert Stearman, Richard D. Klausner, Sohail Malik, William S. Lane, Irina Sorokina, Robert G. Roeder, Joan Weliky Conaway, Ronald C. Conaway

Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16): 10353–10358. Published online 2002 Jul 29. doi: 10.1073/pnas.162424199