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Items: 1 to 20 of 71

1.
Reconstitution of active human core Mediator complex reveals a pivotal role of the MED14 subunit
Murat A. Cevher, Yi Shi, Dan Li, Brian T. Chait, Sohail Malik, Robert G. Roeder
Nat Struct Mol Biol. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: Nat Struct Mol Biol. 2014 Dec; 21(12): 1028–1034. Published online 2014 Nov 10. doi: 10.1038/nsmb.2914
PMCID:
PMC4259101
AbstractArticlePDF–933K
2.
Coactivation of Estrogen Receptor α (ERα)/Sp1 By Vitamin D Receptor Interacting Protein 150 (DRIP150)
Jeongeun Lee, Stephen Safe
Arch Biochem Biophys. Author manuscript; available in PMC 2007 Sep 17.
Published in final edited form as: Arch Biochem Biophys. 2007 May 15; 461(2): 200–210. Published online 2007 Jan 23. doi: 10.1016/j.abb.2006.12.030
PMCID:
PMC1978170
AbstractArticlePDF–746K
3.
Vitamin D Enhances Glucocorticoid Action in Human Monocytes: INVOLVEMENT OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR AND MEDIATOR COMPLEX SUBUNIT 14
Yong Zhang, Donald Y. M. Leung, Elena Goleva
J Biol Chem. 2013 May 17; 288(20): 14544–14553. Published online 2013 Apr 9. doi: 10.1074/jbc.M112.427054
PMCID:
PMC3656308
AbstractArticlePDF–2.3M
4.
Role of Metazoan Mediator Proteins in Interferon-Responsive Transcription
Joe F. Lau, Inna Nusinzon, Darya Burakov, Leonard P. Freedman, Curt M. Horvath
Mol Cell Biol. 2003 Jan; 23(2): 620–628. doi: 10.1128/MCB.23.2.620-628.2003
PMCID:
PMC151539
AbstractArticlePDF–437K
5.
MED14 Tethers Mediator to the N-Terminal Domain of Peroxisome Proliferator-Activated Receptor γ and Is Required for Full Transcriptional Activity and Adipogenesis
Lars Grøntved, Maria S. Madsen, Michael Boergesen, Robert G. Roeder, Susanne Mandrup
Mol Cell Biol. 2010 May; 30(9): 2155–2169. Published online 2010 Mar 1. doi: 10.1128/MCB.01238-09
PMCID:
PMC2863581
AbstractArticlePDF–2.5M
6.
Characterization of Mediator Complexes from HeLa Cell Nuclear Extract
Gang Wang, Greg T. Cantin, Jennitte L. Stevens, Arnold J. Berk
Mol Cell Biol. 2001 Jul; 21(14): 4604–4613. doi: 10.1128/MCB.21.14.4604-4613.2001
PMCID:
PMC87123
AbstractArticlePDF–417K
7.
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220
Melanie Stumpf, Claudia Waskow, Marit Krötschel, Dominic van Essen, Patrick Rodriguez, Xiaoting Zhang, Boris Guyot, Robert G. Roeder, Tilman Borggrefe
Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49): 18504–18509. Published online 2006 Nov 28. doi: 10.1073/pnas.0604494103
Correction in:
Proc Natl Acad Sci U S A. 2007 Jan 23; 104(4): 1442.
PMCID:
PMC1693692
AbstractArticlePDF–1.2M
8.
Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins.
A B Hittelman, D Burakov, J A Iñiguez-Lluhí, L P Freedman, M J Garabedian
EMBO J. 1999 Oct 1; 18(19): 5380–5388. doi: 10.1093/emboj/18.19.5380
PMCID:
PMC1171607
SummaryPDF–335K
9.
TRAP/SMCC/Mediator-Dependent Transcriptional Activation from DNA and Chromatin Templates by Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4
Sohail Malik, Annika E. Wallberg, Yun Kyoung Kang, Robert G. Roeder
Mol Cell Biol. 2002 Aug; 22(15): 5626–5637. doi: 10.1128/MCB.22.15.5626-5637.2002
PMCID:
PMC133960
AbstractArticlePDF–330K
10.
HIF1A employs CDK8-Mediator to stimulate RNAPII elongation
Matthew D. Galbraith, Mary A. Allen, Claire L. Bensard, Xiaoxing Wang, Marie K. Schwinn, Bo Qin, Henry W. Long, Danette L. Daniels, William C. Hahn, Robin D. Dowell, Joaquín M. Espinosa
Cell. Author manuscript; available in PMC 2014 Jun 6.
Published in final edited form as: Cell. 2013 Jun 6; 153(6): 1327–1339. doi: 10.1016/j.cell.2013.04.048
PMCID:
PMC3681429
AbstractArticlePDF–2.7M
11.
Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex.
J D Fondell, H Ge, R G Roeder
Proc Natl Acad Sci U S A. 1996 Aug 6; 93(16): 8329–8333. doi: 10.1073/pnas.93.16.8329
PMCID:
PMC38670
SummaryPage BrowsePDF–1.5M
12.
Characterization of the Influence of Mediator Complex in HIV-1 Transcription
Alba Ruiz, Eduardo Pauls, Roger Badia, Eva Riveira-Muñoz, Bonaventura Clotet, Ester Ballana, José A. Esté
J Biol Chem. 2014 Oct 3; 289(40): 27665–27676. Published online 2014 Aug 6. doi: 10.1074/jbc.M114.570341
PMCID:
PMC4183804
AbstractArticlePDF–1.7M
13.
CDK8 is a positive regulator of transcriptional elongation within the serum response network
Aaron J. Donner, Christopher C. Ebmeier, Dylan J. Taatjes, Joaquín M. Espinosa
Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Aug 11.
Published in final edited form as: Nat Struct Mol Biol. 2010 Feb; 17(2): 194–201. Published online 2010 Jan 24. doi: 10.1038/nsmb.1752
PMCID:
PMC2920286
AbstractArticlePDF–2.1M
14.
A novel docking site on Mediator is critical for activation by VP16 in mammalian cells
Gerhard Mittler, Thomas Stühler, Lisa Santolin, Thomas Uhlmann, Elisabeth Kremmer, F. Lottspeich, Lucia Berti, Michael Meisterernst
EMBO J. 2003 Dec 15; 22(24): 6494–6504. doi: 10.1093/emboj/cdg619
PMCID:
PMC291814
AbstractArticlePDF–382K
15.
Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3
Krista D Meyer, Aaron J Donner, Matthew T Knuesel, Autumn G York, Joaquín M Espinosa, Dylan J Taatjes
EMBO J. 2008 May 21; 27(10): 1447–1457. Published online 2008 Apr 17. doi: 10.1038/emboj.2008.78
PMCID:
PMC2396395
AbstractArticlePDF–303K
16.
A conserved Mediator–CDK8 kinase module association regulates Mediator–RNA polymerase II interaction
Kuang-Lei Tsai, Shigeo Sato, Chieri Tomomori-Sato, Ronald C. Conaway, Joan W. Conaway, Francisco J. Asturias
Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: Nat Struct Mol Biol. 2013 May; 20(5): 611–619. Published online 2013 Apr 7. doi: 10.1038/nsmb.2549
PMCID:
PMC3648612
AbstractArticlePDF–1.4M
17.
The SCF–Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator
Michael A. Davis, Elizabeth A. Larimore, Brian M. Fissel, Jherek Swanger, Dylan J. Taatjes, Bruce E. Clurman
Genes Dev. 2013 Jan 15; 27(2): 151–156. doi: 10.1101/gad.207720.112
PMCID:
PMC3566307
AbstractArticlePDF–1.2M
18.
The TRAP/Mediator coactivator complex interacts directly with estrogen receptors α and β through the TRAP220 subunit and directly enhances estrogen receptor function invitro
Yun Kyoung Kang, Mohamed Guermah, Chao-Xing Yuan, Robert G. Roeder
Proc Natl Acad Sci U S A. 2002 Mar 5; 99(5): 2642–2647. Published online 2002 Feb 26. doi: 10.1073/pnas.261715899
PMCID:
PMC122401
AbstractArticlePDF–285K
19.
Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation
Bethany Mason, Susanne Flach, Felipe R. Teixeira, Raquel Manzano Garcia, Oscar M. Rueda, Jean E. Abraham, Carlos Caldas, Paul A. W. Edwards, Heike Laman
Cell Mol Life Sci. 2020 Jul; 77(13): 2605–2620. Published online 2019 Sep 27. doi: 10.1007/s00018-019-03306-y
PMCID:
PMC7320043
AbstractArticlePDF–2.5M
20.
Quantitative Proteomics of the SMAD (Suppressor of Mothers against Decapentaplegic) Transcription Factor Family Identifies Importin 5 as a Bone Morphogenic Protein Receptor SMAD-specific Importin
Roy Baas, Ayestha Sijm, Hetty A. A. M. van Teeffelen, Robert van Es, Harmjan R. Vos, H. Th. Marc Timmers
J Biol Chem. 2016 Nov 11; 291(46): 24121–24132. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748582
PMCID:
PMC5104937
AbstractArticlePDF–4.4M

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