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Items: 1 to 20 of 99

1.
NAT1 inhibits liver metastasis of colorectal cancer by regulating EMT and glycolysis
Wang Gu, Chen Li, Tingting Shen, Li Tong, Wenkang Yuan, Xiaofei Zheng, Tianqi Wang, Siyu Wang, Benshuai Zhu, Chong Zhang, Chao Zhang
Aging (Albany NY) 2024 Jun 30; 16(12): 10546–10562. Published online 2024 Jun 24. doi: 10.18632/aging.205957
PMCID:
PMC11236320
AbstractArticlePDF–1.8M
2.
Arylamine N-acetyltransferase 1 deficiency inhibits drug-induced cell death in breast cancer cells: switch from cytochrome C-dependent apoptosis to necroptosis
Courtney E. McAleese, Neville J. Butcher, Rodney F. Minchin
Breast Cancer Res Treat. 2022; 195(3): 223–236. Published online 2022 Aug 2. doi: 10.1007/s10549-022-06668-3
PMCID:
PMC9464750
AbstractArticlePDF–2.1M
3.
Deletion of arylamine N-acetyltransferase 1 in MDA-MB-231 human breast cancer cells reduces primary and secondary tumor growth in vivo with no significant effects on metastasis
Mark A. Doll, Andrew R. Ray, Raúl A. Salazar-González, Parag P. Shah, Alexis A. Vega, Sophia M. Sears, Austin M. Krueger, Kyung U. Hong, Levi J. Beverly, David W. Hein
Mol Carcinog. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Mol Carcinog. 2022 May; 61(5): 481–493. Published online 2022 Feb 8. doi: 10.1002/mc.23392
PMCID:
PMC9018511
AbstractArticlePDF–1.7M
4.
CRISPR/Cas9 knockout of human arylamine N-acetyltransferase 1 in MDA-MB-231 breast cancer cells suggests a role in cellular metabolism
Samantha M. Carlisle, Patrick J. Trainor, Kyung U. Hong, Mark A. Doll, David W. Hein
Sci Rep. 2020; 10: 9804. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66863-4
PMCID:
PMC7299936
AbstractArticlePDF–8.4M
5.
NAT1 Genetic Variation Increases Asthma Risk in Children with Secondhand Smoke Exposure
Cassandra C. Brooks, Lisa J. Martin, Valentina Pilipenko, Hua He, Grace K. LeMasters, James E. Lockey, David I. Bernstein, Patrick H. Ryan, Gurjit K. Khurana Hershey, Jocelyn M. Biagini Myers
J Asthma. Author manuscript; available in PMC 2022 Mar 1.
Published in final edited form as: J Asthma. 2021 Mar; 58(3): 284–292. Published online 2019 Dec 6. doi: 10.1080/02770903.2019.1694941
PMCID:
PMC7274907
AbstractArticlePDF–624K
6.
Trimodal distribution of arylamine N-acetyltransferase 1 mRNA in breast cancer tumors: association with overall survival and drug resistance
Rodney F. Minchin, Neville J. Butcher
BMC Genomics. 2018; 19: 513. Published online 2018 Jul 3. doi: 10.1186/s12864-018-4894-4
PMCID:
PMC6029418
AbstractArticlePDF–1.5M
7.
Thiopurine metabolites variations during co-treatment with aminosalicylates for inflammatory bowel disease: Effect of N-acetyl transferase polymorphisms
Gabriele Stocco, Eva Cuzzoni, Sara De Iudicibus, Diego Favretto, Noelia Malusà, Stefano Martelossi, Elena Pozzi, Paolo Lionetti, Alessandro Ventura, Giuliana Decorti
World J Gastroenterol. 2015 Mar 28; 21(12): 3571–3578. Published online 2015 Mar 28. doi: 10.3748/wjg.v21.i12.3571
PMCID:
PMC4375579
AbstractArticlePDF–1001K
8.
N-acetyltransferase 1 polymorphism increases cotinine levels in Caucasian children exposed to secondhand smoke: the CCAAPS birth cohort
Grace K LeMasters, Gurjit K Khurana Hershey, Umasundari Sivaprasad, Lisa J Martin, Valentina Pilipenko, Mark B Ericksen, Jeffrey W Burkle, Mark A Lindsey, David I Bernstein, James E Lockey, Joey Gareri, Angelika Lubetsky, Gideon Koren, Jocelyn M Biagini Myers
Pharmacogenomics J. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: Pharmacogenomics J. 2015 Apr; 15(2): 189–195. Published online 2014 Aug 26. doi: 10.1038/tpj.2014.44
PMCID:
PMC4342329
AbstractArticlePDF–631K
9.
Inflammatory cytokines suppress arylamine N-acetyltransferase 1 in cholangiocarcinoma cells
Benjaporn Buranrat, Auemduan Prawan, Banchob Sripa, Veerapol Kukongviriyapan
World J Gastroenterol. 2007 Dec 14; 13(46): 6219–6225. Published online 2007 Dec 14. doi: 10.3748/wjg.v13.i46.6219
PMCID:
PMC4171233
AbstractArticlePDF–771K
10.
Crippling the Essential GTPase Der Causes Dependence on Ribosomal Protein L9
Anusha Naganathan, Sean D. Moore
J Bacteriol. 2013 Aug; 195(16): 3682–3691. doi: 10.1128/JB.00464-13
PMCID:
PMC3754568
AbstractArticlePDF–1.4M
11.
Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker
Ida Johansson, Cecilia Nilsson, Pontus Berglund, Martin Lauss, Markus Ringnér, Håkan Olsson, Lena Luts, Edith Sim, Sten Thorstensson, Marie-Louise Fjällskog, Ingrid Hedenfalk
Breast Cancer Res. 2012; 14(1): R31. Published online 2012 Feb 14. doi: 10.1186/bcr3116
PMCID:
PMC3496149
AbstractArticlePDF–1.0M
12.
Functional analysis of arylamine N-acetyltransferase 1 (NAT1) NAT1*10 haplotypes in a complete NATb mRNA construct
Lori M. Millner, Mark A. Doll, Marcus W. Stepp, J.Christopher States, David W. Hein
Carcinogenesis. 2012 Feb; 33(2): 348–355. Published online 2011 Nov 22. doi: 10.1093/carcin/bgr273
Correction in:
Carcinogenesis. 2012 Jul; 33(7): 1431.
PMCID:
PMC3271262
AbstractArticlePDF–438K
13.
Functional Effects of Genetic Polymorphisms in the N-acetyltransferase 1 Coding and 3′ Untranslated Regions
Yuanqi Zhu, J. Christopher States, Yang Wang, David W. Hein
Birth Defects Res A Clin Mol Teratol. Author manuscript; available in PMC 2012 Feb 2.
Published in final edited form as: Birth Defects Res A Clin Mol Teratol. 2011 Feb; 91(2): 77–84. Published online 2011 Feb 2. doi: 10.1002/bdra.20763
PMCID:
PMC3252750
AbstractArticlePDF–476K
14.
Phenotype of the Most Common “Slow Acetylator” Arylamine N-Acetyltransferase 1 Genetic Variant (NAT1*14B) Is Substrate-Dependent
Lori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States, David W. Hein
Drug Metab Dispos. 2012 Jan; 40(1): 198–204. doi: 10.1124/dmd.111.041855
PMCID:
PMC3250052
AbstractArticlePDF–639K
15.
NATb/NAT1*4 promotes greater arylamine N-acetyltransferase 1 mediated DNA adducts and mutations than NATa/NAT1*4 following exposure to 4-aminobiphenyl
Lori M. Millner, Mark A. Doll, Jian Cai, J. Christopher States, David W. Hein
Mol Carcinog. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: Mol Carcinog. 2012 Aug; 51(8): 636–646. Published online 2011 Aug 11. doi: 10.1002/mc.20836
PMCID:
PMC3217153
AbstractArticlePDF–1.2M
16.
Human N-acetyltransferase 1 (NAT1) *10 and *11 alleles increase protein expression via distinct mechanisms and associate with sulfamethoxazole-induced hypersensitivity
Danxin Wang, Michael F. Para, Susan L. Koletar, Wolfgang Sadee
Pharmacogenet Genomics. Author manuscript; available in PMC 2012 Oct 1.
Published in final edited form as: Pharmacogenet Genomics. 2011 Oct; 21(10): 652–664. doi: 10.1097/FPC.0b013e3283498ee9
PMCID:
PMC3172334
AbstractArticlePDF–1.2M
17.
Lack of Association of the N-acetyltransferase NAT1*10 Allele with Prostate Cancer Incidence, Grade, or Stage Among Smokers in Finland
LaCreis R. Kidd, David W. Hein, Karen Woodson, Philip R. Taylor, Demetrius Albanes, Jarmo Virtamo, Joseph A. Tangrea
Biochem Genet. Author manuscript; available in PMC 2011 Aug 15.
Published in final edited form as: Biochem Genet. 2011 Feb; 49(1-2): 73–82. Published online 2010 Oct 8. doi: 10.1007/s10528-010-9386-4
PMCID:
PMC3155982
AbstractArticlePDF–68K
18.
Functional effects of single nucleotide polymorphisms in the coding region of human N-acetyltransferase 1
Yuanqi Zhu, David W. Hein
Pharmacogenomics J. Author manuscript; available in PMC 2009 Apr 1.
Published in final edited form as: Pharmacogenomics J. 2008 Oct; 8(5): 339–348. Published online 2007 Oct 2. doi: 10.1038/sj.tpj.6500483
PMCID:
PMC2575040
AbstractArticlePDF–596K
19.
STRUCTURE-FUNCTION ANALYSES OF SINGLE NUCLEOTIDE POLYMORPHISMS IN HUMAN N-ACETYLTRANSFERASE 1
Jason M. Walraven, John O. Trent, David W. Hein
Drug Metab Rev. Author manuscript; available in PMC 2008 Mar 6.
Published in final edited form as: Drug Metab Rev. 2008; 40(1): 169–184. doi: 10.1080/03602530701852917
PMCID:
PMC2265210
AbstractArticlePDF–3.3M
20.
Functional Analysis of the Human N-Acetyltransferase 1 Major Promoter: Quantitation of Tissue Expression and Identification of Critical Sequence Elements
Anwar Husain, Xiaoyan Zhang, Mark A. Doll, J. Christopher States, David F. Barker, David W. Hein
Drug Metab Dispos. Author manuscript; available in PMC 2008 Sep 1.
Published in final edited form as: Drug Metab Dispos. 2007 Sep; 35(9): 1649–1656. Published online 2007 Jun 25. doi: 10.1124/dmd.107.016485
PMCID:
PMC2085369
AbstractArticlePDF–1.1M

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