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Select item 111345511.

Critical amino acid residues regulating TRPA1 Zn²⁺ response: A comparative study across species

Masaki Matsubara, Yukiko Muraki, Hiroka Suzuki, Noriyuki Hatano, Katsuhiko Muraki

J Biol Chem. 2024 Jun; 300(6): 107302. Published online 2024 Apr 18. doi: 10.1016/j.jbc.2024.107302

PMCID:: PMC11134551

Abstract Article PDF–7.8M

Select item 107177362.

FK506 (tacrolimus) causes pain sensation through the activation of transient receptor potential ankyrin 1 (TRPA1) channels

Tomo Kita, Kunitoshi Uchida, Kenichi Kato, Yoshiro Suzuki, Makoto Tominaga, Jun Yamazaki

J Physiol Sci. 2019 Mar; 69(2): 305–316. Published online 2018 Nov 26. doi: 10.1007/s12576-018-0647-z

PMCID:: PMC10717736

Abstract Article PDF–1.4M

Select item 105727253.

Functional TRPA1 Channels Regulate CD56^dimCD16⁺ NK Cell Cytotoxicity against Tumor Cells

Fernanda Scopelliti, Valentina Dimartino, Caterina Cattani, Andrea Cavani

Int J Mol Sci. 2023 Oct; 24(19): 14736. Published online 2023 Sep 29. doi: 10.3390/ijms241914736

PMCID:: PMC10572725

Abstract Article PDF–3.1M

Select item 104717184.

Epigenetic Connections of the TRPA1 Ion Channel in Pain Transmission and Neurogenic Inflammation — a Therapeutic Perspective in Migraine?

Michal Fila, Elzbieta Pawlowska, Joanna Szczepanska, Janusz Blasiak

Mol Neurobiol. 2023; 60(10): 5578–5591. Published online 2023 Jun 16. doi: 10.1007/s12035-023-03428-2

PMCID:: PMC10471718

Abstract Article PDF–1.3M

Select item 104431995.

TRPA1 rare variants in chronic neuropathic and nociplastic pain patients

Margherita Marchi, Erika Salvi, Mirna Andelic, Elkadia Mehmeti, Ilaria D'Amato, Daniele Cazzato, Federica Chiappori, Raffaella Lombardi, Daniele Cartelli, Grazia Devigili, Eleonora Dalla Bella, Monique Gerrits, Rowida Almomani, Rayaz A. Malik, Milena Ślęczkowska, Anna Mazzeo, Luca Gentile, Sulayman Dib-Hajj, Stephen G. Waxman, Catharina G. Faber, Eleonora Vecchio, Marina de Tommaso, Giuseppe Lauria

Pain. 2023 Sep; 164(9): 2048–2059. Published online 2023 Apr 19. doi: 10.1097/j.pain.0000000000002905

PMCID:: PMC10443199

Abstract Article PDF–835K

Select item 103807616.

Transient Receptor Potential Ankyrin 1 (TRPA1) Channel Mediates Acrolein Cytotoxicity in Human Lung Cancer Cells

Akihiko Sakamoto, Yusuke Terui, Kazuei Igarashi, Keiko Kashiwagi

Int J Mol Sci. 2023 Jul; 24(14): 11847. Published online 2023 Jul 24. doi: 10.3390/ijms241411847

PMCID:: PMC10380761

Abstract Article PDF–1.7M

Select item 101990977.

Molecular mechanism of hyperactivation conferred by a truncation of TRPA1

Avnika Bali, Samantha P. Schaefer, Isabelle Trier, Alice L. Zhang, Lilian Kabeche, Candice E. Paulsen

Nat Commun. 2023; 14: 2867. Published online 2023 May 19. doi: 10.1038/s41467-023-38542-1

PMCID:: PMC10199097

Abstract Article PDF–3.7M

Select item 101773998.

Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as a Sensor of Oxidative Stress in Cancer Cells

Francesco Moccia, Daniela Montagna

Cells. 2023 May; 12(9): 1261. Published online 2023 Apr 26. doi: 10.3390/cells12091261

PMCID:: PMC10177399

Abstract Article PDF–1.9M

Select item 99572639.

Transient Receptor Potential Ankyrin 1 (TRPA1) Methylation and Chronic Pain: A Systematic Review

Fulvio Celsi, Francesca Peri, Julia Cavasin, Luisa Zupin, Giorgio Cozzi, Egidio Barbi, Sergio Crovella

Genes (Basel) 2023 Feb; 14(2): 411. Published online 2023 Feb 4. doi: 10.3390/genes14020411

PMCID:: PMC9957263

Abstract Article PDF–3.4M

Select item 985985610.

Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure

Katharina Müller-Dott, Horst Thiermann, Harald John, Dirk Steinritz

Arch Toxicol. 2023; 97(2): 429–439. Published online 2022 Nov 12. doi: 10.1007/s00204-022-03411-1

PMCID:: PMC9859856

Abstract Article PDF–1.3M

Select item 957676611.

The human TRPA1 intrinsic cold and heat sensitivity involves separate channel structures beyond the N-ARD domain

Lavanya Moparthi, Viktor Sinica, Vamsi K. Moparthi, Mohamed Kreir, Thibaut Vignane, Milos R. Filipovic, Viktorie Vlachova, Peter M. Zygmunt

Nat Commun. 2022; 13: 6113. Published online 2022 Oct 17. doi: 10.1038/s41467-022-33876-8

PMCID:: PMC9576766

Abstract Article PDF–4.1M

Select item 938971912.

Activated TRPA1 plays a therapeutic role in TMZ resistance in glioblastoma by altering mitochondrial dynamics

Hao Chen, Chunlin Li, Haiyang Hu, Bin Zhang

BMC Mol Cell Biol. 2022; 23: 38. Published online 2022 Aug 19. doi: 10.1186/s12860-022-00438-1

PMCID:: PMC9389719

Abstract Article PDF–5.3M

Select item 929654913.

2-hydroxyethyl methacrylate-derived reactive oxygen species stimulate ATP release via TRPA1 in human dental pulp cells

Ai Orimoto, Chiaki Kitamura, Kentaro Ono

Sci Rep. 2022; 12: 12343. Published online 2022 Jul 19. doi: 10.1038/s41598-022-16559-8

PMCID:: PMC9296549

Abstract Article PDF–1.9M

Select item 894316214.

Atomistic mechanisms of human TRPA1 activation by electrophile irritants through molecular dynamics simulation and mutual information analysis

Matthew Habgood, David Seiferth, Afroditi-Maria Zaki, Irfan Alibay, Philip C. Biggin

Sci Rep. 2022; 12: 4929. Published online 2022 Mar 23. doi: 10.1038/s41598-022-08824-7

PMCID:: PMC8943162

Abstract Article PDF–2.8M

Select item 882056315.

Transient Receptor Potential Ankyrin 1 Channel: An Evolutionarily Tuned Thermosensor

Viktor SINICA, Viktorie VLACHOVÁ

Physiol Res. 2021 Jun; 70(3): 363–381. Published online 2021 May 12. doi: 10.33549/physiolres.934697

PMCID:: PMC8820563

Abstract Article PDF–1.9M

Select item 880010516.

Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB

Han Wu, Canyang Niu, Yaxuan Qu, Xiaoying Sun, KeWei Wang

J Biol Chem. 2022 Feb; 298(2): 101555. Published online 2021 Dec 30. doi: 10.1016/j.jbc.2021.101555

PMCID:: PMC8800105

Abstract Article PDF–3.0M

Select item 875382117.

Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity: a protocol for an adaptive recall by genotype study

Aidan P. Nickerson, Laura J. Corbin, Nicholas J. Timpson, Keith Phillips, Anthony E. Pickering, James P. Dunham

BMC Med Genomics. 2022; 15: 9. Published online 2022 Jan 12. doi: 10.1186/s12920-022-01156-5

PMCID:: PMC8753821

Abstract Article PDF–1.8M

Select item 862484218.

The TRPA1 Channel Amplifies the Oxidative Stress Signal in Melanoma

Francesco De Logu, Daniel Souza Monteiro de Araujo, Filippo Ugolini, Luigi Francesco Iannone, Margherita Vannucchi, Francesca Portelli, Lorenzo Landini, Mustafa Titiz, Vincenzo De Giorgi, Pierangelo Geppetti, Daniela Massi, Romina Nassini

Cells. 2021 Nov; 10(11): 3131. Published online 2021 Nov 11. doi: 10.3390/cells10113131

PMCID:: PMC8624842

Abstract Article PDF–7.4M

Select item 803749719.

Transient Receptor Potential Ankyrin 1 (TRPA1)—An Inflammation-Induced Factor in Human HaCaT Keratinocytes

Samu Luostarinen, Mari Hämäläinen, Eeva Moilanen

Int J Mol Sci. 2021 Apr; 22(7): 3322. Published online 2021 Mar 24. doi: 10.3390/ijms22073322

PMCID:: PMC8037497

Abstract Article PDF–1.9M

Select item 781997320.

Functional expression of the transient receptor potential ankyrin type 1 channel in pancreatic adenocarcinoma cells

Florentina Cojocaru, Tudor Şelescu, Dan Domocoş, Luminiţa Măruţescu, Gabriela Chiritoiu, Nicoleta-Raluca Chelaru, Simona Dima, Dan Mihăilescu, Alexandru Babes, Dana Cucu

Sci Rep. 2021; 11: 2018. Published online 2021 Jan 21. doi: 10.1038/s41598-021-81250-3

Correction in:: Sci Rep. 2021; 11: 8853.

PMCID:: PMC7819973

Abstract Article PDF–5.5M

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