PMC Links for Gene (Select 89849) - PMC

Select item 96290821.

The role of ATG16L2 in autophagy and disease

Laurence Don Wai Luu, Nadeem O. Kaakoush, Natalia Castaño-Rodríguez

Autophagy. 2022; 18(11): 2537–2546. Published online 2022 Mar 3. doi: 10.1080/15548627.2022.2042783

PMCID:: PMC9629082

Select item 61243062.

Potentially Functional variants of ATG16L2 predict radiation pneumonitis and outcomes in patients with non-small cell lung cancer after definitive radiotherapy

Juyi Wen, Hongliang Liu, Lili Wang, Xiaomeng Wang, Ning Gu, Zhensheng Liu, Ting Xu, Daniel R. Gomez, Ritsuko Komaki, Zhongxing Liao, Qingyi Wei

J Thorac Oncol. Author manuscript; available in PMC 2018 Sep 5.

Published in final edited form as: J Thorac Oncol. 2018 May; 13(5): 660–675. Published online 2018 Feb 15. doi: 10.1016/j.jtho.2018.01.028

PMCID:: PMC6124306

Abstract Article PDF–785K

Select item 69003793.

Potentially functional variants of autophagy‐related genes are associated with the efficacy and toxicity of radiotherapy in patients with nasopharyngeal carcinoma

Zhiguang Yang, Zhaoyu Liu

Mol Genet Genomic Med. 2019 Dec; 7(12): e1030. Published online 2019 Nov 6. doi: 10.1002/mgg3.1030

PMCID:: PMC6900379

Abstract Article PDF–415K

Select item 49813304.

Identification of a systemic lupus erythematosus risk locus spanning ATG16L2, FCHSD2, and P2RY2 in Koreans

Christopher J. Lessard, Satria Sajuthi, Jian Zhao, Kwangwoo Kim, John A. Ice, He Li, Hannah Ainsworth, Astrid Rasmussen, Jennifer A. Kelly, Mindy Marion, So-Young Bang, Young Bin Joo, Jeongim Choi, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Soo-Kon Lee, Jung-Yoon Choe, Seung Cheol Shim, Ji Hee Oh, Young Jin Kim, Bok-Ghee Han, Nan Shen, Hwee Siew Howe, Edward K. Wakeland, Quan-Zhen Li, Yeong Wook Song, Patrick M. Gaffney, Marta E. Alarcón-Riquelme, Lindsey A. Criswell, Chaim O. Jacob, Robert P. Kimberly, Timothy J. Vyse, John B. Harley, Kathy L. Sivils, Sang-Cheol Bae, Carl D. Langefeld, Betty P. Tsao

Arthritis Rheumatol. Author manuscript; available in PMC 2016 Aug 11.

Published in final edited form as: Arthritis Rheumatol. 2016 May; 68(5): 1197–1209. doi: 10.1002/art.39548

PMCID:: PMC4981330

Abstract Article PDF–865K

Select item 67968555.

ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12–ATG5-ATG16L1 complex assembly and autophagy

Daric J. Wible, Hsueh-Ping Chao, Dean G. Tang, Shawn B. Bratton

Cell Discov. 2019; 5: 42. Published online 2019 Aug 27. doi: 10.1038/s41421-019-0110-1

PMCID:: PMC6796855

Abstract Article PDF–3.1M

Select item 36357206.

Loss of acinar cell IKKα triggers spontaneous pancreatitis in mice

Ning Li, Xuefeng Wu, Ryan G. Holzer, Jun-Hee Lee, Jelena Todoric, Eek-Joong Park, Hisanobu Ogata, Anna S. Gukovskaya, Ilya Gukovsky, Donald P. Pizzo, Scott VandenBerg, David Tarin, Çiǧdem Atay, Melek C. Arkan, Thomas J. Deerinck, Jorge Moscat, Maria Diaz-Meco, David Dawson, Mert Erkan, Jörg Kleeff, Michael Karin

J Clin Invest. 2013 May 1; 123(5): 2231–2243. Published online 2013 Apr 8. doi: 10.1172/JCI64498

PMCID:: PMC3635720

Abstract Article PDF–4.5M

Select item 35402077.

Structure of the human ATG12~ATG5 conjugate required for LC3 lipidation in autophagy

Chinatsu Otomo, Zoltan Metlagel, Giichi Takaesu, Takanori Otomo

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jul 1.

Published in final edited form as: Nat Struct Mol Biol. 2013 Jan; 20(1): 59–66. Published online 2012 Dec 2. doi: 10.1038/nsmb.2431

PMCID:: PMC3540207

Abstract Article PDF–3.3M

Select item 32880238.

Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex

Koutaro Ishibashi, Naonobu Fujita, Eiko Kanno, Hiroko Omori, Tamotsu Yoshimori, Takashi Itoh, Mitsunori Fukuda

Autophagy. 2011 Dec 1; 7(12): 1500–1513. doi: 10.4161/auto.7.12.18025

PMCID:: PMC3288023

Abstract Article

Select item 44016629.

FBXW7 modulates cellular stress response and metastatic potential via HSF1 post-translational modification

Nikos Kourtis, Rana S. Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T. Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt, Emily I. Chen, Julide T. Celebi, Charalampos Lazaris, Aristotelis Tsirigos, Iman Osman, Eva Hernando, Iannis Aifantis

Nat Cell Biol. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Cell Biol. 2015 Mar; 17(3): 322–332. doi: 10.1038/ncb3121

PMCID:: PMC4401662

Abstract Article PDF–5.0M

Select item 962668810.

Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis

Xi Ling, Jiayi Lu, Xiaoyun Wang, Lan Liu, Lu Liu, Yadi Wang, Yujun Sun, Chune Ren, Chao Lu, Zhenhai Yu

iScience. 2022 Nov 18; 25(11): 105363. Published online 2022 Oct 14. doi: 10.1016/j.isci.2022.105363

PMCID:: PMC9626688

Abstract Article PDF–6.0M

Select item 1007290611.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 633346012.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 476457313.

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning

Koray Kırlı, Samir Karaca, Heinz Jürgen Dehne, Matthias Samwer, Kuan Ting Pan, Christof Lenz, Henning Urlaub, Dirk Görlich

eLife. 2015; 4: e11466. Published online 2015 Dec 17. doi: 10.7554/eLife.11466

PMCID:: PMC4764573

Abstract Article PDF–5.7M

Select item 616668214.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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