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Select item 70121051.

β-TrCP1 promotes cell proliferation via TNF-dependent NF-κB activation in diffuse large B cell lymphoma

Nannan Cai, Zhuolin Chen, Yuejiao Huang, Shan Shao, Haiyan Yu, Yuchan Wang, Song He

Cancer Biol Ther. 2020; 21(3): 241–247. Published online 2019 Nov 15. doi: 10.1080/15384047.2019.1683332

PMCID:: PMC7012105

Abstract Article PDF–2.3M

Select item 47471872.

EBV-miR-BART10-3p facilitates epithelial-mesenchymal transition and promotes metastasis of nasopharyngeal carcinoma by targeting BTRC

Qijia Yan, Zhaoyang Zeng, Zhaojian Gong, Wenling Zhang, Xiayu Li, Baoyu He, Yali Song, Qiao Li, Yong Zeng, Qianjin Liao, Pan Chen, Lei Shi, Songqing Fan, Bo Xiang, Jian Ma, Ming Zhou, Xiaoling Li, Jianbo Yang, Wei Xiong, Guiyuan Li

Oncotarget. 2015 Dec 8; 6(39): 41766–41782. Published online 2015 Oct 19. doi: 10.18632/oncotarget.6155

PMCID:: PMC4747187

Abstract Article PDF–14M

Select item 107754483.

Decidual stromal cells-derived exosomes incurred insufficient migration and invasion of trophoblast by disturbing of β-TrCP-mediated snail ubiquitination and degradation in unexplained recurrent spontaneous abortion

Miao Xiong, Qiaohong Wang, Xiaoxin Zhang, Liping Wen, Aimin Zhao

Eur J Med Res. 2024; 29: 39. Published online 2024 Jan 9. doi: 10.1186/s40001-023-01598-2

PMCID:: PMC10775448

Abstract Article PDF–2.9M

Select item 97952484.

Pan-cancer analysis of FBXW family with potential implications in prognosis and immune infiltration

Tingting Huang, XIaoxiao OuYang, Jiwei Li, Bingbing Shi, Zhengda Shan, Zhiyuan Shi, Zhangru Yang

Front Immunol. 2022; 13: 1084339. Published online 2022 Dec 14. doi: 10.3389/fimmu.2022.1084339

PMCID:: PMC9795248

Abstract Article PDF–7.5M

Select item 87636495.

WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple‐negative breast cancer via NF‐κB activation

Yvonne Xinyi Lim, Hexian Lin, Tinghine Chu, Yoon Pin Lim

Mol Oncol. 2022 Jan; 16(2): 422–446. Published online 2021 Aug 12. doi: 10.1002/1878-0261.13048

PMCID:: PMC8763649

Abstract Article PDF–6.5M

Select item 78865676.

miR-193a-3p Promotes the Invasion, Migration, and Mesenchymal Transition in Glioma through Regulating BTRC

Dan-Dan Zhou, Hong-Li Li, Wei Liu, Li-Ping Zhang, Quan Zheng, Jun Bai, Ya-Qiong Hu, Chong-Gao Yin, Shi-Jun Lv, Bao-Gang Zhang

Biomed Res Int. 2021; 2021: 8928509. Published online 2021 Feb 9. doi: 10.1155/2021/8928509

PMCID:: PMC7886567

Abstract Article PDF–3.8M

Select item 71985747.

The circular RNA FAM169A functions as a competitive endogenous RNA and regulates intervertebral disc degeneration by targeting miR-583 and BTRC

Wei Guo, Kun Mu, Bin Zhang, Chao Sun, Ling Zhao, Zhan-Yin Dong, Qing Cui

Cell Death Dis. 2020 May; 11(5): 315. Published online 2020 May 4. doi: 10.1038/s41419-020-2543-8

PMCID:: PMC7198574

Abstract Article PDF–4.5M

Select item 70131418.

lncRNA SLC7A11-AS1 Promotes Chemoresistance by Blocking SCF^β-TRCP-Mediated Degradation of NRF2 in Pancreatic Cancer

Qingzhu Yang, Kai Li, Xuemei Huang, Chen Zhao, Yu Mei, Xinyuan Li, Lin Jiao, Huanjie Yang

Mol Ther Nucleic Acids. 2020 Mar 6; 19: 974–985. Published online 2020 Jan 11. doi: 10.1016/j.omtn.2019.11.035

PMCID:: PMC7013141

Abstract Article PDF–2.8M

Select item 55484229.

Genetic Variants in WNT2B and BTRC Predict Melanoma Survival

Qiong Shi, Hongliang Liu, Peng Han, Chunying Li, Yanru Wang, Wenting Wu, Dakai Zhu, Christopher I. Amos, Shenying Fang, Jeffrey E. Lee, Jiali Han, Qingyi Wei

J Invest Dermatol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: J Invest Dermatol. 2017 Aug; 137(8): 1749–1756. Published online 2017 May 10. doi: 10.1016/j.jid.2017.04.023

PMCID:: PMC5548422

Abstract Article PDF–676K

Select item 541716510.

βTrCP Controls GH Receptor Degradation via Two Different Motifs

Ana C. da Silva Almeida, Ger J. Strous, Agnes G. S. H. van Rossum

Mol Endocrinol. January 1, 2012; 26(1): 165–177. Published online 2011 Oct 27. doi: 10.1210/me.2011-1211

PMCID:: PMC5417165

Abstract Article

Select item 515950111.

E3 Ligase SCF^βTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells

Qiang Liu, Yu Tang, Long Chen, Na Liu, Fangfang Lang, Heng Liu, Pin Wang, Xiulian Sun

J Biol Chem. 2016 Dec 16; 291(51): 26399–26409. Published online 2016 Nov 2. doi: 10.1074/jbc.M116.717553

PMCID:: PMC5159501

Abstract Article PDF–3.0M

Select item 512276812.

Ubiquitin-dependent Turnover of Adenosine Deaminase Acting on RNA 1 (ADAR1) Is Required for Efficient Antiviral Activity of Type I Interferon

Lemin Li, Guanghui Qian, Yibo Zuo, Yukang Yuan, Qiao Cheng, Tingting Guo, Jin Liu, Chang Liu, Liting Zhang, Hui Zheng

J Biol Chem. 2016 Nov 25; 291(48): 24974–24985. Published online 2016 Oct 11. doi: 10.1074/jbc.M116.737098

PMCID:: PMC5122768

Abstract Article PDF–2.7M

Select item 479069813.

Downregulation of vascular endothelial growth factor receptor-2 under oxidative stress conditions is mediated by β-transduction repeat-containing protein via glycogen synthase kinase-3β signaling

WEN WU, DAIMIN ZHANG, DAORONG PAN, GUANGFENG ZUO, XIAOMIN REN, SHAOLIANG CHEN

Int J Mol Med. 2016 Apr; 37(4): 911–920. Published online 2016 Feb 18. doi: 10.3892/ijmm.2016.2493

PMCID:: PMC4790698

Abstract Article PDF–1.1M

Select item 467328814.

A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice

Ramaswamy Sharma, Paul J. Williams, Anjana Gupta, Brandon McCluskey, Shylesh Bhaskaran, Steve Muñoz, Babatunde O. Oyajobi

Oncotarget. 2015 Aug 28; 6(25): 21589–21602. Published online 2015 May 12. doi: 10.18632/oncotarget.4120

PMCID:: PMC4673288

Abstract Article PDF–3.2M

Select item 422331415.

Ras Regulates SCF^β-TrCP Protein Activity and Specificity via Its Effector Protein NORE1A

M. Lee Schmidt, Howard Donninger, Geoffrey J. Clark

J Biol Chem. 2014 Nov 7; 289(45): 31102–31110. Published online 2014 Sep 12. doi: 10.1074/jbc.M114.594283

PMCID:: PMC4223314

Abstract Article PDF–2.0M

Select item 414090416.

DNA Damage Induces the Accumulation of Tiam1 by Blocking β-TrCP-dependent Degradation

Guixin Zhu, Zhongyun Fan, Miao Ding, Libing Mu, Juan Liang, Yajie Ding, Yu Fu, Binlu Huang, Wei Wu

J Biol Chem. 2014 May 30; 289(22): 15482–15494. Published online 2014 Apr 15. doi: 10.1074/jbc.M114.553388

PMCID:: PMC4140904

Abstract Article PDF–1.9M

Select item 347057017.

Targeting the Oncogenic E3 Ligase Skp2 in Prostate and Breast Cancer Cells with a Novel Energy Restriction-Mimetic Agent

Shuo Wei, Po-Chen Chu, Hsiao-Ching Chuang, Wen-Chun Hung, Samuel K. Kulp, Ching-Shih Chen

PLoS One. 2012; 7(10): e47298. Published online 2012 Oct 12. doi: 10.1371/journal.pone.0047298

PMCID:: PMC3470570

Abstract Article PDF–2.5M

Select item 346279318.

Erioflorin Stabilizes the Tumor Suppressor Pdcd4 by Inhibiting Its Interaction with the E3-ligase β-TrCP1

Johanna S. Blees, Heidi R. Bokesch, Daniela Rübsamen, Kathrin Schulz, Larissa Milke, Magdalena M. Bajer, Kirk R. Gustafson, Curtis J. Henrich, James B. McMahon, Nancy H. Colburn, Tobias Schmid, Bernhard Brüne

PLoS One. 2012; 7(10): e46567. Published online 2012 Oct 2. doi: 10.1371/journal.pone.0046567

PMCID:: PMC3462793

Abstract Article PDF–633K

Select item 343113119.

DEPTOR ubiquitination and destruction by SCF^β-TrCP

Zhiwei Wang, Jiateng Zhong, Daming Gao, Hiroyuki Inuzuka, Pengda Liu, Wenyi Wei

Am J Physiol Endocrinol Metab. 2012 Jul 15; 303(2): E163–E169. Published online 2012 Mar 27. doi: 10.1152/ajpendo.00105.2012

PMCID:: PMC3431131

Abstract Article

Select item 313335820.

PEST Motif Serine and Tyrosine Phosphorylation Controls Vascular Endothelial Growth Factor Receptor 2 Stability and Downregulation

Rosana D. Meyer, Srimathi Srinivasan, Amrik J. Singh, John E. Mahoney, Kobra Rezazadeh Gharahassanlou, Nader Rahimi

Mol Cell Biol. 2011 May; 31(10): 2010–2025. doi: 10.1128/MCB.01006-10

PMCID:: PMC3133358

Abstract Article PDF–4.3M

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PMC Links for Gene (Select 8945) (348)
PMC
PREDICTED: Homo sapiens beta-transducin repeat containing E3 ubiquitin protein l...
PREDICTED: Homo sapiens beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC), transcript variant X11, mRNA
gi|2217279338|ref|XM_047425986.1|

Nucleotide
PREDICTED: Homo sapiens beta-transducin repeat containing E3 ubiquitin protein l...
PREDICTED: Homo sapiens beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC), transcript variant X5, mRNA
gi|2217279329|ref|XM_047425983.1|

Nucleotide
zk07h08.r1 Soares_pregnant_uterus_NbHPU Homo sapiens cDNA clone IMAGE:469887 5',...
zk07h08.r1 Soares_pregnant_uterus_NbHPU Homo sapiens cDNA clone IMAGE:469887 5', mRNA sequence
gi|1494274|gnl|dbEST|642220|gb|AA02 1|

Nucleotide

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