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Select item 66944751.

Increased HERV-E clone 4–1 expression contributes to DNA hypomethylation and IL-17 release from CD4⁺ T cells via miR-302d/MBD2 in systemic lupus erythematosus

Xin Wang, Chaoshuai Zhao, Chengzhong Zhang, Xingyu Mei, Jun Song, Yue Sun, Zhouwei Wu, Weimin Shi

Cell Commun Signal. 2019; 17: 94. Published online 2019 Aug 14. doi: 10.1186/s12964-019-0416-5

PMCID:: PMC6694475

Abstract Article PDF–2.7M

Select item 64418862.

Obesity‐induced MBD2_v2 expression promotes tumor‐initiating triple‐negative breast cancer stem cells

Emily A. Teslow, Cristina Mitrea, Bin Bao, Ramzi M. Mohammad, Lisa A. Polin, Greg Dyson, Kristen S. Purrington, Aliccia Bollig‐Fischer

Mol Oncol. 2019 Apr; 13(4): 894–908. Published online 2019 Mar 1. doi: 10.1002/1878-0261.12444

PMCID:: PMC6441886

Abstract Article PDF–824K

Select item 60679003.

Deletion of MBD2 inhibits proliferation of chronic myeloid leukaemia blast phase cells

Ling Cheng, Ying Tang, Xing Chen, Lei Zhao, Songya Liu, Yanna Ma, Na Wang, Kuangguo Zhou, Jianfeng Zhou, Mi Zhou

Cancer Biol Ther. 2018; 19(8): 676–686. Published online 2018 Apr 19. doi: 10.1080/15384047.2018.1450113

PMCID:: PMC6067900

Abstract Article PDF–1.4M

Select item 49400514.

MBD2 as a novel marker associated with poor survival of patients with hepatocellular carcinoma after hepatic resection

Wei Liu, Na Wang, Min Lu, Xiao-Juan Du, Bao-Cai Xing

Mol Med Rep. 2016 Aug; 14(2): 1617–1623. Published online 2016 Jun 15. doi: 10.3892/mmr.2016.5404

PMCID:: PMC4940051

Abstract Article PDF–735K

Select item 44991365.

Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells

Guillaume Devailly, Mélodie Grandin, Laury Perriaud, Pauline Mathot, Jean-Guy Delcros, Yannick Bidet, Anne-Pierre Morel, Jean-Yves Bignon, Alain Puisieux, Patrick Mehlen, Robert Dante

Nucleic Acids Res. 2015 Jul 13; 43(12): 5838–5854. Published online 2015 May 24. doi: 10.1093/nar/gkv508

PMCID:: PMC4499136

Abstract Article PDF–7.8M

Select item 42160576.

Synergistic effects of combined DNA methyltransferase inhibition and MBD2 depletion on breast cancer cells; MBD2 depletion blocks 5-aza-2ʹ-deoxycytidine-triggered invasiveness

David Cheishvili, Flora Chik, Chen Chen Li, Bishnu Bhattacharya, Matthew Suderman, Ani Arakelian, Michael Hallett, Shafaat A. Rabbani, Moshe Szyf

Carcinogenesis. 2014 Nov; 35(11): 2436–2446. Published online 2014 Sep 1. doi: 10.1093/carcin/bgu181

PMCID:: PMC4216057

Abstract Article PDF–1.5M

Select item 40571707.

Genome-Wide Binding of MBD2 Reveals Strong Preference for Highly Methylated Loci

Roberta Menafra, Arie B. Brinkman, Filomena Matarese, Gianluigi Franci, Stefanie J. J. Bartels, Luan Nguyen, Takashi Shimbo, Paul A. Wade, Nina C. Hubner, Hendrik G. Stunnenberg

PLoS One. 2014; 9(6): e99603. Published online 2014 Jun 13. doi: 10.1371/journal.pone.0099603

PMCID:: PMC4057170

Abstract Article PDF–4.3M

Select item 33552658.

A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility

Yadav Sapkota, Paula Robson, Raymond Lai, Carol E Cass, John R Mackey, Sambasivarao Damaraju

Eur J Hum Genet. 2012 Jun; 20(6): 682–689. Published online 2012 Jan 18. doi: 10.1038/ejhg.2011.273

PMCID:: PMC3355265

Abstract Article PDF–463K

Select item 31575699.

Methyl Binding Domain Protein 2 (MBD2) dependent proliferation and survival of breast cancer cells

Omar Y. Mian, Shou Zhen Wang, Sheng Zu Zhu, Merlin N. Gnanapragasam, Laura Graham, Harry D. Bear, Gordon D. Ginder

Mol Cancer Res. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: Mol Cancer Res. 2011 Aug; 9(8): 1152–1162. Published online 2011 Jun 21. doi: 10.1158/1541-7786.MCR-11-0252

PMCID:: PMC3157569

Abstract Article PDF–2.6M

Select item 237515610.

Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer

C Müller-Tidow, K Kügler, S Diederichs, S Klümpen, M Möller, U Vogt, R Metzger, P M Schneider, W E Berdel, H Serve

Br J Cancer. 2001 Oct; 85(8): 1168–1174. doi: 10.1054/bjoc.2001.2041

PMCID:: PMC2375156

Summary PDF–99K

Select item 124214111.

Genotypes and haplotypes of the methyl-CpG-binding domain 2 modify breast cancer risk dependent upon menopausal status

Yong Zhu, Heather N Brown, Yawei Zhang, Theodore R Holford, Tongzhang Zheng

Breast Cancer Res. 2005; 7(5): R745–R752. Published online 2005 Jul 19. doi: 10.1186/bcr1283

PMCID:: PMC1242141

Abstract Article PDF–150K

Select item 952002612.

Densely methylated DNA traps Methyl-CpG–binding domain protein 2 but permits free diffusion by Methyl-CpG–binding domain protein 3

Gage O. Leighton, Elizabeth Marie Irvin, Parminder Kaur, Ming Liu, Changjiang You, Dhruv Bhattaram, Jacob Piehler, Robert Riehn, Hong Wang, Hai Pan, David C. Williams, Jr.

J Biol Chem. 2022 Oct; 298(10): 102428. Published online 2022 Aug 28. doi: 10.1016/j.jbc.2022.102428

PMCID:: PMC9520026

Abstract Article PDF–3.6M

Select item 945364813.

Blockade of Mbd2 by siRNA-loaded liposomes protects mice against OVA-induced allergic airway inflammation via repressing M2 macrophage production

Guo-Rao Wu, Min Zhou, Yi Wang, Qing Zhou, Lei Zhang, Long He, Shu Zhang, Qilin Yu, Yongjian Xu, Jianping Zhao, Weining Xiong, Cong-Yi Wang

Front Immunol. 2022; 13: 930103. Published online 2022 Aug 25. doi: 10.3389/fimmu.2022.930103

PMCID:: PMC9453648

Abstract Article PDF–18M

Select item 583666314.

Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD

Zhilin Zeng, Miao Li, Jinkun Chen, Qinghai Li, Qin Ning, Jianping Zhao, Yongjian Xu, Jungang Xie, Jun Yu

Int J Chron Obstruct Pulmon Dis. 2018; 13: 703–715. Published online 2018 Feb 28. doi: 10.2147/COPD.S148595

PMCID:: PMC5836663

Abstract Article PDF–4.5M

Select item 568267415.

MBD2 upregulates miR-301a-5p to induce kidney cell apoptosis during vancomycin-induced AKI

Juan Wang, Huiling Li, Shuangfa Qiu, Zheng Dong, Xudong Xiang, Dongshan Zhang

Cell Death Dis. 2017 Oct; 8(10): e3120. Published online 2017 Oct 12. doi: 10.1038/cddis.2017.509

PMCID:: PMC5682674

Abstract Article PDF–6.0M

Select item 558773416.

CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level

Hai Pan, Stephanie M. Bilinovich, Parminder Kaur, Robert Riehn, Hong Wang, David C. Williams, Jr

Nucleic Acids Res. 2017 Sep 6; 45(15): 9164–9177. Published online 2017 Jun 20. doi: 10.1093/nar/gkx548

PMCID:: PMC5587734

Abstract Article PDF–5.0M

Select item 493602217.

Epigenetic silencing of serine protease HTRA1 drives polyploidy

Nina Schmidt, Inga Irle, Kamilla Ripkens, Vanda Lux, Jasmin Nelles, Christian Johannes, Lee Parry, Kirsty Greenow, Sarah Amir, Mara Campioni, Alfonso Baldi, Chio Oka, Masashi Kawaichi, Alan R. Clarke, Michael Ehrmann

BMC Cancer. 2016; 16: 399. Published online 2016 Jul 7. doi: 10.1186/s12885-016-2425-8

PMCID:: PMC4936022

Abstract Article PDF–2.4M

Select item 469563918.

Downregulation of miR-221 Inhibits Cell Migration and Invasion through Targeting Methyl-CpG Binding Domain Protein 2 in Human Oral Squamous Cell Carcinoma Cells

Shuqi He, Renfa Lai, Dan Chen, Wangxiang Yan, Zhaoqiang Zhang, Zhiguo Liu, Xueqiang Ding, Yu Chen

Biomed Res Int. 2015; 2015: 751672. Published online 2015 Dec 16. doi: 10.1155/2015/751672

PMCID:: PMC4695639

Abstract Article PDF–3.5M

Select item 408273519.

Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

Yu Lu, Yuin-Han Loh, Hu Li, Marcella Cesana, Scott B. Ficarro, Jignesh R. Parikh, Nathan Salomonis, Cheng-Xu Delon Toh, Stelios T. Andreadis, C. John Luckey, James J. Collins, George Q. Daley, Jarrod A. Marto

Cell Stem Cell. Author manuscript; available in PMC 2015 Jul 3.

Published in final edited form as: Cell Stem Cell. 2014 Jul 3; 15(1): 92–101. Published online 2014 May 8. doi: 10.1016/j.stem.2014.04.002