PMC Links for Gene (Select 8861) - PMC

Sebastián A. García, Anka Swiersy, Praveen Radhakrishnan, Vittorio Branchi, Lahiri Kanth Nanduri, Balázs Győrffy, Alexander M. Betzler, Ulrich Bork, Christoph Kahlert, Christoph Reißfelder, Nuh N. Rahbari, Jürgen Weitz, Sebastian Schölch

Oncotarget. 2016 Dec 20; 7(51): 84258–84270. Published online 2016 Oct 5. doi: 10.18632/oncotarget.12481

PMCID:: PMC5356660

Abstract Article PDF–5.3M

Select item 104232854.

LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1

Lihui Lu, Jianwei Wang, Fang Fang, Ailian Guo, Shuting Jiang, Yanfang Tao, Yongping Zhang, Yan Li, Kunlong Zhang, Zimu Zhang, Ran Zhuo, Xinran Chu, Xiaolu Li, Yuanyuan Tian, Li Ma, Xu Sang, Yanling Chen, Juanjuan Yu, Yang Yang, Haibo Cao, Jizhao Gao, Jun Lu, Shaoyan Hu, Jian Pan, Hailong He

Cell Death Dis. 2023 Aug; 14(8): 518. Published online 2023 Aug 12. doi: 10.1038/s41419-023-06039-w

PMCID:: PMC10423285

Abstract Article PDF–6.8M

Select item 69697055.

RING Finger Protein 38 Mediates LIM Domain Binding 1 Degradation and Regulates Cell Growth in Colorectal Cancer

Ziming Huang, Peng Yang, Hengfa Ge, Chenchen Yang, Yong Cai, Zhen Chen, Wenze Tian, Haixiao Wang

Onco Targets Ther. 2020; 13: 371–379. Published online 2020 Jan 14. doi: 10.2147/OTT.S234828

PMCID:: PMC6969705

Abstract Article PDF–6.0M

Select item 69694946.

Crystal structure of human LDB1 in complex with SSBP2

Hongyang Wang, Juhyun Kim, Zhizhi Wang, Xiao-Xue Yan, Ann Dean, Wenqing Xu

Proc Natl Acad Sci U S A. 2020 Jan 14; 117(2): 1042–1048. Published online 2019 Dec 31. doi: 10.1073/pnas.1914181117

PMCID:: PMC6969494

Abstract Article PDF–1.9M

Select item 47194247.

LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding

Justin H. Layer, Catherine E. Alford, W. Hayes McDonald, Utpal P. Davé

Mol Cell Biol. 2016 Feb 1; 36(3): 488–506. Prepublished online 2015 Nov 23. Published online 2016 Jan 19. doi: 10.1128/MCB.00901-15

PMCID:: PMC4719424

Abstract Article PDF–2.9M

Select item 33751238.

Regulation of LIM-Domain-Binding 1 Protein Expression by Ubiquitination of Lysine-134

Paul W. Howard, Shall F. Jue, David G. Ransom, Richard A. Maurer

Biochem J. Author manuscript; available in PMC 2012 Jun 14.

Published in final edited form as: Biochem J. 2010 Jul 1; 429(1): 127–136. doi: 10.1042/BJ20091461

PMCID:: PMC3375123

Abstract Article PDF–5.6M

Select item 41174419.

The Co-factor of LIM Domains (CLIM/LDB/NLI) Maintains Basal Mammary Epithelial Stem Cells and Promotes Breast Tumorigenesis

Michael L. Salmans, Zhengquan Yu, Kazuhide Watanabe, Eric Cam, Peng Sun, Padhraic Smyth, Xing Dai, Bogi Andersen

PLoS Genet. 2014 Jul; 10(7): e1004520. Published online 2014 Jul 31. doi: 10.1371/journal.pgen.1004520

PMCID:: PMC4117441

Abstract Article PDF–5.2M

Select item 289143510.

Transcription Intermediary Factor 1γ Decreases Protein Expression of the Transcriptional Cofactor, LIM-Domain-Binding 1

Paul W. Howard, David G. Ransom, Richard A. Maurer

Biochem Biophys Res Commun. Author manuscript; available in PMC 2011 Jun 4.

Published in final edited form as: Biochem Biophys Res Commun. 2010 Jun 4; 396(3): 674–678. Published online 2010 May 4. doi: 10.1016/j.bbrc.2010.04.160

PMCID:: PMC2891435

Abstract Article PDF–679K

Select item 116993311.

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins.

I A Wadman, H Osada, G G Grütz, A D Agulnick, H Westphal, A Forster, T H Rabbitts

EMBO J. 1997 Jun 2; 16(11): 3145–3157. doi: 10.1093/emboj/16.11.3145

PMCID:: PMC1169933

Summary PDF–764K

Select item 519970112.

LIM domain–binding 1 maintains the terminally differentiated state of pancreatic β cells

Benjamin N. Ediger, Hee-Woong Lim, Christine Juliana, David N. Groff, LaQueena T. Williams, Giselle Dominguez, Jin-Hua Liu, Brandon L. Taylor, Erik R. Walp, Vasumathi Kameswaran, Juxiang Yang, Chengyang Liu, Chad S. Hunter, Klaus H. Kaestner, Ali Naji, Changhong Li, Maike Sander, Roland Stein, Lori Sussel, Kyoung-Jae Won, Catherine Lee May, Doris A. Stoffers

J Clin Invest. 2017 Jan 3; 127(1): 215–229. Published online 2016 Dec 12. doi: 10.1172/JCI88016

PMCID:: PMC5199701

Abstract Article PDF–4.9M

Select item 271382613.

Regulation of Estrogen-Dependent Transcription by the LIM Cofactors CLIM and RLIM in Breast Cancer

Steven A. Johnsen, Cenap Güngör, Tanja Prenzel, Sabine Riethdorf, Lutz Riethdorf, Naoko Taniguchi-Ishigaki, Thomas Rau, Baris Tursun, J. David Furlow, Guido Sauter, Martin Scheffner, Klaus Pantel, Frank Gannon, Ingolf Bach

Cancer Res. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Cancer Res. 2009 Jan 1; 69(1): 128–136. doi: 10.1158/0008-5472.CAN-08-1630

PMCID:: PMC2713826

Abstract Article PDF–1.8M

Select item 184771214.

Single-stranded DNA-binding proteins regulate the abundance of LIM domain and LIM domain-binding proteins

Zhixiong Xu, Xianzhang Meng, Ying Cai, Hong Liang, Lalitha Nagarajan, Stephen J. Brandt

Genes Dev. 2007 Apr 15; 21(8): 942–955. doi: 10.1101/gad.1528507

PMCID:: PMC1847712

Abstract Article PDF–797K

Select item 15606815.

Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4

Janet E. Deane, Joel P. Mackay, Ann H.Y. Kwan, Eleanor Y.M. Sum, Jane E. Visvader, Jacqueline M. Matthews

EMBO J. 2003 May 1; 22(9): 2224–2233. doi: 10.1093/emboj/cdg196

PMCID:: PMC156068

Abstract Article PDF–582K

Select item 1108264116.

An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation

Chunlin Wang, Maoting Hu, Kunlin Yu, Wuling Liu, Anling Hu, Yi Kuang, Lei Huang, Babu Gajendran, Eldad Zacksenhaus, Xiao Xiao, Yaacov Ben-David

Mol Med Rep. 2024 Jun; 29(6): 107. Published online 2024 Apr 26. doi: 10.3892/mmr.2024.13231

PMCID:: PMC11082641

Abstract Article PDF–4.3M

Select item 373253517.

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis

Xiao-Jian Sun, Zhanxin Wang, Lan Wang, Yanwen Jiang, Nils Kost, T. David Soong, Wei-Yi Chen, Zhanyun Tang, Tomoyoshi Nakadai, Olivier Elemento, Wolfgang Fischle, Ari Melnick, Dinshaw J. Patel, Stephen D. Nimer, Robert G. Roeder

Nature. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Nature. 2013 Aug 1; 500(7460): 93–97. Published online 2013 Jun 30. doi: 10.1038/nature12287