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Select item 85345511.

A Novel Pro-Inflammatory Mechanosensing Pathway Orchestrated by the Disintegrin Metalloproteinase ADAM15 in Synovial Fibroblasts

Tomasz Janczi, Florian Meier, Yuliya Fehrl, Raimund W. Kinne, Beate Böhm, Harald Burkhardt

Cells. 2021 Oct; 10(10): 2705. Published online 2021 Oct 9. doi: 10.3390/cells10102705

PMCID:: PMC8534551

Abstract Article PDF–2.9M

Select item 84369182.

ADAM15 correlates with prognosis, immune infiltration and apoptosis in hepatocellular carcinoma

Jun Hui Xu, Yong Jun Guan, Yi Chao Zhang, Zhen Dong Qiu, Yu Zhou, Chen Chen, Jia Yu, Wei Xing Wang

Aging (Albany NY) 2021 Aug 31; 13(16): 20395–20417. Published online 2021 Aug 23. doi: 10.18632/aging.203425

PMCID:: PMC8436918

Abstract Article PDF–3.9M

Select item 78515653.

ADAM15 Participates in Tick-Borne Encephalitis Virus Replication

Qi Yang, Rongjuan Pei, Yun Wang, Yuan Zhou, Min Yang, Xinwen Chen, Jizheng Chen

J Virol. 2021 Feb; 95(4): e01926-20. Prepublished online 2020 Nov 18. Published online 2021 Jan 28. doi: 10.1128/JVI.01926-20

PMCID:: PMC7851565

Abstract Article PDF–4.8M

Select item 73646364.

ADAM15 expression is increased in lung CD8⁺ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction

Xiaoyun Wang, Duo Zhang, Andrew Higham, Sophie Wolosianka, Xiaoyan Gai, Lu Zhou, Hans Petersen, Victor Pinto-Plata, Miguel Divo, Edwin K. Silverman, Bartolome Celli, Dave Singh, Yongchang Sun, Caroline A. Owen

Respir Res. 2020; 21: 188. Published online 2020 Jul 16. doi: 10.1186/s12931-020-01446-5

PMCID:: PMC7364636

Abstract Article PDF–1.4M

Select item 65123615.

ADAM15 modulates outside‐in signalling in chondrocyte–matrix interactions

Beate B. Böhm, Andrea Schirner, Harald Burkhardt

J Cell Mol Med. 2009 Aug; 13(8b): 2634–2644. Published online 2008 Sep 4. doi: 10.1111/j.1582-4934.2008.00490.x

PMCID:: PMC6512361

Abstract Article PDF–743K

Select item 63567466.

A Disintegrin and Metalloprotease 15 is Expressed on Rheumatoid Arthritis Synovial Tissue Endothelial Cells and may Mediate Angiogenesis

Shinichiro Nishimi, Takeo Isozaki, Kuninobu Wakabayashi, Hiroko Takeuchi, Tsuyoshi Kasama

Cells. 2019 Jan; 8(1): 32. Published online 2019 Jan 9. doi: 10.3390/cells8010032

PMCID:: PMC6356746

Abstract Article PDF–2.0M

Select item 53443247.

Overexpression of the A Disintegrin and Metalloproteinase ADAM15 is linked to a Small but Highly Aggressive Subset of Prostate Cancers

Christoph Burdelski, Michael Fitzner, Claudia Hube-Magg, Martina Kluth, Asmus Heumann, Ronald Simon, Till Krech, Till Clauditz, Franziska Büscheck, Stefan Steurer, Corinna Wittmer, Andrea Hinsch, Andreas M. Luebke, Frank Jacobsen, Sarah Minner, Maria Christina Tsourlakis, Burkhard Beyer, Thomas Steuber, Imke Thederan, Guido Sauter, Jakob Izbicki, Thorsten Schlomm, Waldemar Wilczak

Neoplasia. 2017 Apr; 19(4): 279–287. Published online 2017 Mar 8. doi: 10.1016/j.neo.2017.01.005

PMCID:: PMC5344324

Abstract Article PDF–1.4M

Select item 47730418.

ADAM15 Is Functionally Associated with the Metastatic Progression of Human Bladder Cancer

Guadalupe Lorenzatti Hiles, Amanda Bucheit, John R. Rubin, Alexandra Hayward, Angelica L. Cates, Kathleen C. Day, Layla El-Sawy, L. Priya Kunju, Stephanie Daignault, Cheryl T. Lee, Monica Liebert, Maha Hussain, Mark L. Day

PLoS One. 2016; 11(3): e0150138. Published online 2016 Mar 1. doi: 10.1371/journal.pone.0150138

PMCID:: PMC4773041

Abstract Article PDF–905K

Select item 45785679.

The ADAM15 ectodomain is shed from secretory exosomes

Hee Doo Lee, Yeon Hyang Kim, Bon-Hun Koo, Doo-Sik Kim

BMB Rep. 2015 May; 48(5): 277–282. doi: 10.5483/BMBRep.2015.48.5.161

PMCID:: PMC4578567

Abstract Article PDF–11M

Select item 214805910.

ADAM15 gene structure and differential alternative exon use in human tissues

Iivari Kleino, Rebekka M Ortiz, Ari-Pekka J Huovila

BMC Mol Biol. 2007; 8: 90. Published online 2007 Oct 15. doi: 10.1186/1471-2199-8-90

PMCID:: PMC2148059

Abstract Article PDF–844K

Select item 160068111.

ADAM15 Disintegrin Is Associated with Aggressive Prostate and Breast Cancer Disease

Rainer Kuefer, Kathleen C Day, Celina G Kleer, Michael S Sabel, Matthias D Hofer, Sooryanarayana Varambally, Christoph S Zorn, Ami M Chinnaiyan, Mark A Rubin, Mark L Day

Neoplasia. 2006 Apr; 8(4): 319–329. doi: 10.1593/neo.05682

PMCID:: PMC1600681

Abstract Article PDF–981K

Select item 737097512.

ADAM (a Disintegrin and Metalloproteinase) 15 Deficiency Exacerbates Ang II (Angiotensin II)–Induced Aortic Remodeling Leading to Abdominal Aortic Aneurysm

Sayantan Jana, Michael Chute, Mei Hu, Gerrit Winkelaar, Caroline A. Owen, Gavin Y. Oudit, Zamaneh Kassiri

Arterioscler Thromb Vasc Biol. 2020 Aug; 40(8): 1918–1934. Published online 2020 Jun 11. doi: 10.1161/ATVBAHA.120.314600

PMCID:: PMC7370975

Abstract Article PDF–9.2M

Select item 671570413.

ADAM15 mediates upregulation of Claudin-1 expression in breast cancer cells

Jens Mattern, Christian S. Roghi, Melanie Hurtz, Vera Knäuper, Dylan R. Edwards, Zaruhi Poghosyan

Sci Rep. 2019; 9: 12540. Published online 2019 Aug 29. doi: 10.1038/s41598-019-49021-3

PMCID:: PMC6715704

Abstract Article PDF–3.5M

Select item 419825214.

MicroRNA-147b Regulates Vascular Endothelial Barrier Function by Targeting ADAM15 Expression

Victor Chatterjee, Richard S. Beard, Jr, Jason J. Reynolds, Ricci Haines, Mingzhang Guo, Matthew Rubin, Jenny Guido, Mack H. Wu, Sarah Y. Yuan

PLoS One. 2014; 9(10): e110286. Published online 2014 Oct 15. doi: 10.1371/journal.pone.0110286

PMCID:: PMC4198252

Abstract Article PDF–1.2M

Select item 337554315.

ADAM15 Protein Amplifies Focal Adhesion Kinase Phosphorylation under Genotoxic Stress Conditions

Dorothee Fried, Beate B. Böhm, Kristin Krause, Harald Burkhardt

J Biol Chem. 2012 Jun 15; 287(25): 21214–21223. Published online 2012 Apr 27. doi: 10.1074/jbc.M112.347120

PMCID:: PMC3375543

Abstract Article PDF–1.7M

Select item 401875216.

Nuclear trafficking of the HIV-1 pre-integration complex depends on the ADAM10 intracellular domain

Mark A. Endsley, Anoma D. Somasunderam, Guangyu Li, Numan Oezguen, Varatharasa Thiviyanathan, James L. Murray, Donald H. Rubin, Thomas W. Hodge, William A. O’Brien, Briana Lewis, Monique R. Ferguson

Virology. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Virology. 2014 Apr; 0: 60–66. Published online 2014 Feb 22. doi: 10.1016/j.virol.2014.02.006

PMCID:: PMC4018752

Abstract Article PDF–745K

Select item 289553917.

ADAM15 regulates endothelial permeability and neutrophil migration via Src/ERK1/2 signalling

Chongxiu Sun, Mack H. Wu, Mingzhang Guo, Mark L. Day, Eugene S. Lee, Sarah Y. Yuan

Cardiovasc Res. 2010 Jul 15; 87(2): 348–355. Published online 2010 Feb 26. doi: 10.1093/cvr/cvq060

PMCID:: PMC2895539

Abstract Article PDF–407K

Select item 244059818.

The Ectodomain Shedding of E-cadherin by ADAM15 Supports ErbB Receptor Activation

Abdo J. Najy, Kathleen C. Day, Mark L. Day

J Biol Chem. 2008 Jun 27; 283(26): 18393–18401. doi: 10.1074/jbc.M801329200

PMCID:: PMC2440598

Abstract Article PDF–436K

Select item 16632919.

Potential Role for ADAM15 in Pathological Neovascularization in Mice

Keisuke Horiuchi, Gisela Weskamp, Lawrence Lum, Hans-Peter Hammes, Hui Cai, Thomas A. Brodie, Thomas Ludwig, Riccardo Chiusaroli, Roland Baron, Klaus T. Preissner, Katia Manova, Carl P. Blobel

Mol Cell Biol. 2003 Aug; 23(16): 5614–5624. doi: 10.1128/MCB.23.16.5614-5624.2003

PMCID:: PMC166329

Abstract Article PDF–1.4M

Select item 122060120.

Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.

K K Nelson, J Schlöndorff, C P Blobel

Biochem J. 1999 Nov 1; 343(Pt 3): 673–680.

PMCID:: PMC1220601

Summary PDF–238K

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