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Items: 1 to 20 of 266

1.
Differential stability of Gcn4p controls its cell-specific activity in differentiated yeast colonies
Libuše Váchová, Vítězslav Plocek, Jana Maršíková, Stanislava Rešetárová, Ladislava Hatáková, Zdena Palková
mBio. 2024 May; 15(5): e00689-24. Published online 2024 Apr 16. doi: 10.1128/mbio.00689-24
PMCID:
PMC11077963
AbstractArticlePDF–20M
2.
Multiomics of GCN4-Dependent Replicative Lifespan Extension Models Reveals Gcn4 as a Regulator of Protein Turnover in Yeast
Blaise L. Mariner, Daniel P. Felker, Ryla J. Cantergiani, Jack Peterson, Mark A. McCormick
Int J Mol Sci. 2023 Nov; 24(22): 16163. Published online 2023 Nov 10. doi: 10.3390/ijms242216163
PMCID:
PMC10671045
AbstractArticlePDF–1.9M
3.
Gcn4 impacts metabolic fluxes to promote yeast chronological lifespan
Juan Facundo Gulias, Florencia Niesi, Martín Arán, Susana Correa-García, Mariana Bermúdez-Moretti
PLoS One. 2023; 18(10): e0292949. Published online 2023 Oct 13. doi: 10.1371/journal.pone.0292949
PMCID:
PMC10575530
AbstractArticlePDF–2.0M
4.
Stochastic scanning events on the GCN4 mRNA 5’ untranslated region generate cell-to-cell heterogeneity in the yeast nutritional stress response
Xiang Meng, Alan Reed, Sandie Lai, Juraj Szavits-Nossan, John E G McCarthy
Nucleic Acids Res. 2023 Jul 21; 51(13): 6609–6621. Published online 2023 May 29. doi: 10.1093/nar/gkad433
PMCID:
PMC10359597
AbstractArticlePDF–1.3M
5.
Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program
Rajalakshmi Srinivasan, Adhish S. Walvekar, Zeenat Rashida, Aswin Seshasayee, Sunil Laxman
PLoS Genet. 2020 Dec; 16(12): e1009252. Published online 2020 Dec 30. doi: 10.1371/journal.pgen.1009252
PMCID:
PMC7773203
AbstractArticlePDF–2.2M
6.
Selective Translation Complex Profiling Reveals Staged Initiation and Co-translational Assembly of Initiation Factor Complexes
Susan Wagner, Anna Herrmannová, Vladislava Hronová, Stanislava Gunišová, Neelam D. Sen, Ross D. Hannan, Alan G. Hinnebusch, Nikolay E. Shirokikh, Thomas Preiss, Leoš Shivaya Valášek
Mol Cell. 2020 Aug 20; 79(4): 546–560.e7. doi: 10.1016/j.molcel.2020.06.004
PMCID:
PMC7447980
AbstractArticle
7.
Nuclear Magnetic Resonance Structures of GCN4p Are Largely Conserved When Ion Pairs Are Disrupted at Acidic pH but Show a Relaxation of the Coiled Coil Superhelix
Anne R. Kaplan, Megan R. Brady, Mark W. Maciejewski, Richard A. Kammerer, Andrei T. Alexandrescu
Biochemistry. Author manuscript; available in PMC 2019 Jan 31.
Published in final edited form as: Biochemistry. 2017 Mar 21; 56(11): 1604–1619. Published online 2017 Mar 9. doi: 10.1021/acs.biochem.6b00634
PMCID:
PMC6355156
AbstractArticlePDF–1.1M
8.
Methionine coordinates a hierarchically organized anabolic program enabling proliferation
Adhish S. Walvekar, Rajalakshmi Srinivasan, Ritu Gupta, Sunil Laxman
Mol Biol Cell. 2018 Dec 15; 29(26): 3183–3200. doi: 10.1091/mbc.E18-08-0515
PMCID:
PMC6340205
AbstractArticlePDF–3.5M
9.
Analysis of NMR Spin-Relaxation Data Using an Inverse Gaussian Distribution Function
Andrew Hsu, Fabien Ferrage, Arthur G. Palmer, III
Biophys J. 2018 Dec 18; 115(12): 2301–2309. Published online 2018 Nov 6. doi: 10.1016/j.bpj.2018.10.030
Correction in:
Biophys J. 2020 Aug 18; 119(4): 884–885.
PMCID:
PMC6301913
AbstractArticlePDF–738K
10.
Gcn4 binding in coding regions can activate internal and canonical 5′ promoters in yeast
Yashpal Rawal, Răzvan V. Chereji, Vishalini Valabhoju, Hongfang Qiu, Josefina Ocampo, David J. Clark, Alan G. Hinnebusch
Mol Cell. Author manuscript; available in PMC 2019 Apr 19.
Published in final edited form as: Mol Cell. 2018 Apr 19; 70(2): 297–311.e4. Published online 2018 Apr 5. doi: 10.1016/j.molcel.2018.03.007
PMCID:
PMC6133248
AbstractArticlePDF–1.9M
11.
Dynamics of GCN4 Facilitate DNA Interaction: A Model-Free Analysis of an Intrinsically Disordered Region
Michelle L. Gill, R. Andrew Byrd, Arthur G. Palmer, III
Phys Chem Chem Phys. Author manuscript; available in PMC 2017 Feb 17.
Published in final edited form as: Phys Chem Chem Phys. 2016 Feb 17; 18(8): 5839–5849. doi: 10.1039/c5cp06197k
PMCID:
PMC4894059
AbstractArticlePDF–1.7M
12.
Reconfiguration of Transcriptional Control of Lysine Biosynthesis in Candida albicans Involves a Central Role for the Gcn4 Transcriptional Activator
Yumnam Priyadarshini, Krishnamurthy Natarajan
mSphere. 2016 Jan-Feb; 1(1): e00016-15. Published online 2016 Jan 22. doi: 10.1128/mSphere.00016-15
PMCID:
PMC4863609
AbstractArticlePDF–1.2M
13.
In-depth analysis of cis-determinants that either promote or inhibit reinitiation on GCN4 mRNA after translation of its four short uORFs
Stanislava Gunišová, Petra Beznosková, Mahabub Pasha Mohammad, Vladislava Vlčková, Leoš Shivaya Valášek
RNA. 2016 Apr; 22(4): 542–558. doi: 10.1261/rna.055046.115
PMCID:
PMC4793210
AbstractArticlePDF–514K
14.
Conformational Dynamics of the Partially Disordered Yeast Transcription Factor GCN4
Paul Robustelli, Nikola Trbovic, Richard A. Friesner, Arthur G. Palmer, III
J Chem Theory Comput. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: J Chem Theory Comput. 2013 Nov 1; 9(11): 10.1021/ct400654r. Published online 2013 Sep 19. doi: 10.1021/ct400654r
PMCID:
PMC3882080
AbstractArticlePDF–750K
15.
The Native GCN4 Leucine-Zipper Domain Does Not Uniquely Specify a Dimeric Oligomerization State
Kaylyn M. Oshaben, Reza Salari, Darrell R. McCaslin, Lillian T. Chong, W. Seth Horne
Biochemistry. Author manuscript; available in PMC 2013 Nov 27.
Published in final edited form as: Biochemistry. 2012 Nov 27; 51(47): 9581–9591. Published online 2012 Nov 13. doi: 10.1021/bi301132k
PMCID:
PMC3535301
AbstractArticlePDF–3.2M
16.
The bZIP dimer localizes at DNA full-sites where each basic region can alternately translocate and bind to subsites at the half-site
I-San Chan, Taufik Al-Sarraj, S. Hesam Shahravan, Anna V. Fedorova, Jumi A. Shin
Biochemistry. Author manuscript; available in PMC 2013 Aug 21.
Published in final edited form as: Biochemistry. 2012 Aug 21; 51(33): 6632–6643. Published online 2012 Aug 10. doi: 10.1021/bi300718f
PMCID:
PMC3430380
AbstractArticlePDF–1.8M
17.
Structural basis of RNA binding by leucine zipper GCN4
Yaroslav Nikolaev, Konstantin Pervushin
Protein Sci. 2012 May; 21(5): 667–676. Published online 2012 Feb 28. doi: 10.1002/pro.2051
PMCID:
PMC3403464
AbstractArticlePDF–877K
18.
Translation Reinitiation Relies on the Interaction between eIF3a/TIF32 and Progressively Folded cis-Acting mRNA Elements Preceding Short uORFs
Vanda Munzarová, Josef Pánek, Stanislava Gunišová, István Dányi, Béla Szamecz, Leoš Shivaya Valášek
PLoS Genet. 2011 Jul; 7(7): e1002137. Published online 2011 Jul 7. doi: 10.1371/journal.pgen.1002137
PMCID:
PMC3131280
AbstractArticlePDF–1.4M
19.
An upstream ORF with non-AUG start codon is translated in vivo but dispensable for translational control of GCN4 mRNA
Fan Zhang, Alan G. Hinnebusch
Nucleic Acids Res. 2011 Apr; 39(8): 3128–3140. Published online 2011 Jan 10. doi: 10.1093/nar/gkq1251
PMCID:
PMC3082883
AbstractArticlePDF–2.5M
20.
Exploring the trigger sequence of the GCN4 coiled-coil: Biased molecular dynamics resolves apparent inconsistencies in NMR measurements
John H Missimer, Jožica Dolenc, Michel O Steinmetz, Wilfred F van Gunsteren
Protein Sci. 2010 Dec; 19(12): 2462–2474. Published online 2010 Oct 15. doi: 10.1002/pro.528
PMCID:
PMC3009413
AbstractArticlePDF–4.0M

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