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Select item 74949161.

DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4

Jonathan Bohlen, Liza Harbrecht, Saioa Blanco, Katharina Clemm von Hohenberg, Kai Fenzl, Günter Kramer, Bernd Bukau, Aurelio A. Teleman

Nat Commun. 2020; 11: 4676. Published online 2020 Sep 16. doi: 10.1038/s41467-020-18452-2

PMCID:: PMC7494916

Abstract Article PDF–2.6M

Select item 63299872.

Crystal structure of the DENR-MCT-1 complex revealed zinc-binding site essential for heterodimer formation

Ivan B. Lomakin, Sergey E. Dmitriev, Thomas A. Steitz

Proc Natl Acad Sci U S A. 2019 Jan 8; 116(2): 528–533. Published online 2018 Dec 24. doi: 10.1073/pnas.1809688116

PMCID:: PMC6329987

Abstract Article PDF–1.8M

Select item 60132343.

DENR–MCTS1 heterodimerization and tRNA recruitment are required for translation reinitiation

Yasar Luqman Ahmed, Sibylle Schleich, Jonathan Bohlen, Nicolas Mandel, Bernd Simon, Irmgard Sinning, Aurelio A. Teleman

PLoS Biol. 2018 Jun; 16(6): e2005160. Published online 2018 Jun 11. doi: 10.1371/journal.pbio.2005160

PMCID:: PMC6013234

Abstract Article PDF–5.8M

Select item 55514854.

Crystal structure of the human ribosome in complex with DENR-MCT-1

Ivan B. Lomakin, Elena A. Stolboushkina, Anand T. Vaidya, Chenguang Zhao, Maria B. Garber, Sergey E. Dmitriev, Thomas A. Steitz

Cell Rep. Author manuscript; available in PMC 2017 Aug 10.

Published in final edited form as: Cell Rep. 2017 Jul 18; 20(3): 521–528. doi: 10.1016/j.celrep.2017.06.025

PMCID:: PMC5551485

Abstract Article PDF–1.2M

Select item 49063735.

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation

Matilda A. Haas, Linh Ngo, Shan Shan Li, Sibylle Schleich, Zhengdong Qu, Hannah K. Vanyai, Hayley D. Cullen, Aida Cardona-Alberich, Ivan E. Gladwyn-Ng, Alistair T. Pagnamenta, Jenny C. Taylor, Helen Stewart, Usha Kini, Kent E. Duncan, Aurelio A. Teleman, David A. Keays, Julian I.-T. Heng

Cell Rep. 2016 Jun 7; 15(10): 2251–2265. Published online 2016 May 26. doi: 10.1016/j.celrep.2016.04.090

PMCID:: PMC4906373

Abstract Article

Select item 88139216.

Cyclin B/CDK1 and Cyclin A/CDK2 phosphorylate DENR to promote mitotic protein translation and faithful cell division

Katharina Clemm von Hohenberg, Sandra Müller, Sibylle Schleich, Matthias Meister, Jonathan Bohlen, Thomas G. Hofmann, Aurelio A. Teleman

Nat Commun. 2022; 13: 668. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28265-0

PMCID:: PMC8813921

Abstract Article PDF–2.3M

Select item 112602887.

To initiate or not to initiate: A critical assessment of eIF2A, eIF2D, and MCT-1·DENR to deliver initiator tRNA to ribosomes

Daisy J. Grove, Paul J. Russell, Michael G. Kearse

Wiley Interdiscip Rev RNA. Author manuscript; available in PMC 2024 Jul 21.

Published in final edited form as: Wiley Interdiscip Rev RNA. 2024 Mar-Apr; 15(2): e1833. doi: 10.1002/wrna.1833

PMCID:: PMC11260288

Abstract Article PDF–938K

Select item 29225068.

Activities of Ligatin and MCT-1/DENR in eukaryotic translation initiation and ribosomal recycling

Maxim A. Skabkin, Olga V. Skabkina, Vidya Dhote, Anton A. Komar, Christopher U.T. Hellen, Tatyana V. Pestova

Genes Dev. 2010 Aug 15; 24(16): 1787–1801. doi: 10.1101/gad.1957510

PMCID:: PMC2922506

Abstract Article PDF–1.3M

Select item 1486689.

Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells.

J J Oh, D R Grosshans, S G Wong, D J Slamon

Nucleic Acids Res. 1999 Oct 15; 27(20): 4008–4017. doi: 10.1093/nar/27.20.4008

PMCID:: PMC148668

Summary PDF–614K

Select item 153856410.

A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics

Ryo Yonashiro, Satoshi Ishido, Shinkou Kyo, Toshifumi Fukuda, Eiji Goto, Yohei Matsuki, Mari Ohmura-Hoshino, Kiyonao Sada, Hak Hotta, Hirohei Yamamura, Ryoko Inatome, Shigeru Yanagi

EMBO J. 2006 Aug 9; 25(15): 3618–3626. Published online 2006 Jul 27. doi: 10.1038/sj.emboj.7601249

PMCID:: PMC1538564

Abstract Article PDF–445K

Select item 161837711.

MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology

Nobuhiro Nakamura, Yasuo Kimura, Masaki Tokuda, Shinji Honda, Shigehisa Hirose

EMBO Rep. 2006 Oct; 7(10): 1019–1022. Published online 2006 Aug 25. doi: 10.1038/sj.embor.7400790

PMCID:: PMC1618377

Abstract Article PDF–132K

Select item 232327012.

cdc2–cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner

Ewan M Smith, Christopher G Proud

EMBO J. 2008 Apr 9; 27(7): 1005–1016. Published online 2008 Mar 13. doi: 10.1038/emboj.2008.39

PMCID:: PMC2323270

Abstract Article PDF–367K

Select item 189911113.

Distinct class of putative “non-conserved” promoters in humans: Comparative studies of alternative promoters of human and mouse genes

Katsuki Tsuritani, Takuma Irie, Riu Yamashita, Yuta Sakakibara, Hiroyuki Wakaguri, Akinori Kanai, Junko Mizushima-Sugano, Sumio Sugano, Kenta Nakai, Yutaka Suzuki

Genome Res. 2007 Jul; 17(7): 1005–1014. doi: 10.1101/gr.6030107

PMCID:: PMC1899111

Abstract Article PDF–757K

Select item 676993014.

Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners

Eunate Gallardo-Vara, Lidia Ruiz-Llorente, Juan Casado-Vela, María J. Ruiz-Rodríguez, Natalia López-Andrés, Asit K. Pattnaik, Miguel Quintanilla, Carmelo Bernabeu

Cells. 2019 Sep; 8(9): 1082. Published online 2019 Sep 13. doi: 10.3390/cells8091082

PMCID:: PMC6769930

Abstract Article PDF–4.3M

Select item 282753815.

A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks

Etsuko Miyamoto-Sato, Shigeo Fujimori, Masamichi Ishizaka, Naoya Hirai, Kazuyo Masuoka, Rintaro Saito, Yosuke Ozawa, Katsuya Hino, Takanori Washio, Masaru Tomita, Tatsuhiro Yamashita, Tomohiro Oshikubo, Hidetoshi Akasaka, Jun Sugiyama, Yasuo Matsumoto, Hiroshi Yanagawa

PLoS One. 2010; 5(2): e9289. Published online 2010 Feb 24. doi: 10.1371/journal.pone.0009289

PMCID:: PMC2827538

Abstract Article PDF–676K

Select item 619728716.

Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II

Yujing Li, Yunhua Liu, Hanchen Xu, Guanglong Jiang, Kevin Van der Jeught, Yuanzhang Fang, Zhuolong Zhou, Lu Zhang, Michael Frieden, Lifei Wang, Zhenhua Luo, Milan Radovich, Bryan P. Schneider, Yibin Deng, Yunlong Liu, Kun Huang, Bin He, Jin Wang, Xiaoming He, Xinna Zhang, Guang Ji, Xiongbin Lu

Nat Commun. 2018; 9: 4394. Published online 2018 Oct 22. doi: 10.1038/s41467-018-06811-z

PMCID:: PMC6197287

Abstract Article PDF–1.9M

Select item 661481417.

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA

You Li, Li Wang, Efraín E Rivera-Serrano, Xian Chen, Stanley M Lemon

Nucleic Acids Res. 2019 Jul 9; 47(12): 6411–6424. Published online 2019 Apr 18. doi: 10.1093/nar/gkz278

PMCID:: PMC6614814

Abstract Article PDF–4.9M

Select item 596587218.

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrP^C) in Alzheimer’s disease

Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt

PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659

PMCID:: PMC5965872

Abstract Article PDF–2.4M

Select item 488905019.

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage

Joshua M. Gilmore, Mihaela E. Sardiu, Brad D. Groppe, Janet L. Thornton, Xingyu Liu, Gerald Dayebgadoh, Charles A. Banks, Brian D. Slaughter, Jay R. Unruh, Jerry L. Workman, Laurence Florens, Michael P. Washburn

PLoS One. 2016; 11(6): e0155492. Published online 2016 Jun 1. doi: 10.1371/journal.pone.0155492

PMCID:: PMC4889050

Abstract Article PDF–5.5M

Select item 555356820.

A role for mitochondrial translation in promotion of viability in K-Ras mutant cells

Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge

Cell Rep. Author manuscript; available in PMC 2017 Aug 11.

Published in final edited form as: Cell Rep. 2017 Jul 11; 20(2): 427–438. doi: 10.1016/j.celrep.2017.06.061

PMCID:: PMC5553568

Abstract Article PDF–1.8M

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PMC Links for Gene (Select 8562) (52)
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GDS5357[ACCN] (15617)
GEO Profiles
fl30d07.x1 Sugano Kawakami zebrafish DRA Danio rerio cDNA clone IMAGE:3815460 3'...
fl30d07.x1 Sugano Kawakami zebrafish DRA Danio rerio cDNA clone IMAGE:3815460 3', mRNA sequence
gi|13101631|gnl|dbEST|7966551|gb|BG 4.1|

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