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Select item 21328001.

Fab1p Is Essential for PtdIns(3)P 5-Kinase Activity and the Maintenance of Vacuolar Size and Membrane Homeostasis

Jonathan D. Gary, Andrew E. Wurmser, Cecilia J. Bonangelino, Lois S. Weisman, Scott D. Emr

J Cell Biol. 1998 Oct 5; 143(1): 65–79. doi: 10.1083/jcb.143.1.65

PMCID:: PMC2132800

Abstract Article PDF–594K

Select item 3075242.

Vacuole Size Control: Regulation of PtdIns(3,5)P₂ Levels by the Vacuole-associated Vac14-Fig4 Complex, a PtdIns(3,5)P₂-specific Phosphatase

Simon A. Rudge, Deborah M. Anderson, Scott D. Emr

Mol Biol Cell. 2004 Jan; 15(1): 24–36. doi: 10.1091/mbc.E03-05-0297

PMCID:: PMC307524

Abstract Article PDF–915K

Select item 2325413.

Vac7p, a novel vacuolar protein, is required for normal vacuole inheritance and morphology.

C J Bonangelino, N L Catlett, L S Weisman

Mol Cell Biol. 1997 Dec; 17(12): 6847–6858. doi: 10.1128/mcb.17.12.6847

PMCID:: PMC232541

Summary PDF–1.5M

Select item 1022654.

Regulation of Fab1 Phosphatidylinositol 3-Phosphate 5-Kinase Pathway by Vac7 Protein and Fig4, a Polyphosphoinositide Phosphatase Family Member

Jonathan D. Gary, Trey K. Sato, Christopher J. Stefan, Cecilia J. Bonangelino, Lois S. Weisman, Scott D. Emr

Mol Biol Cell. 2002 Apr; 13(4): 1238–1251. doi: 10.1091/mbc.01-10-0498

PMCID:: PMC102265

Abstract Article PDF–772K

Select item 20637025.

The Vac14p–Fig4p complex acts independently of Vac7p and couples PI3,5P₂ synthesis and turnover

Jason E. Duex, Fusheng Tang, Lois S. Weisman

J Cell Biol. 2006 Feb 27; 172(5): 693–704. doi: 10.1083/jcb.200512105

PMCID:: PMC2063702

Abstract Article PDF–3.6M

Select item 14596616.

Phosphoinositide 5-Phosphatase Fig4p Is Required for both Acute Rise and Subsequent Fall in Stress-Induced Phosphatidylinositol 3,5-Bisphosphate Levels

Jason E. Duex, Johnathan J. Nau, Emily J. Kauffman, Lois S. Weisman

Eukaryot Cell. 2006 Apr; 5(4): 723–731. doi: 10.1128/EC.5.4.723-731.2006

PMCID:: PMC1459661

Abstract Article PDF–781K

Select item 20435477.

Atg18 Regulates Organelle Morphology and Fab1 Kinase Activity Independent of Its Membrane Recruitment by Phosphatidylinositol 3,5-Bisphosphate

Jem A. Efe, Roberto J. Botelho, Scott D. Emr

Mol Biol Cell. 2007 Nov; 18(11): 4232–4244. doi: 10.1091/mbc.E07-04-0301

PMCID:: PMC2043547

Abstract Article PDF–1.0M

Select item 83535218.

Vacuolar H⁺-ATPase dysfunction rescues intralumenal vesicle cargo sorting in yeast lacking PI(3,5)P₂ or Doa4

Zachary N. Wilson, Dalton Buysse, Matt West, Daniel Ahrens, Greg Odorizzi

J Cell Sci. 2021 Aug 1; 134(15): jcs258459. Published online 2021 Aug 3. doi: 10.1242/jcs.258459

PMCID:: PMC8353521

Abstract Article

Select item 54966209.

Early protection to stress mediated by CDK-dependent PI3,5P₂ signaling from the vacuole/lysosome

Natsuko Jin, Yui Jin, Lois S. Weisman

J Cell Biol. 2017 Jul 3; 216(7): 2075–2090. doi: 10.1083/jcb.201611144

PMCID:: PMC5496620

Abstract Article PDF–2.6M

Select item 343193410.

Yeast vacuoles fragment in an asymmetrical two-phase process with distinct protein requirements

Martin Zieger, Andreas Mayer

Mol Biol Cell. 2012 Sep 1; 23(17): 3438–3449. doi: 10.1091/mbc.E12-05-0347

PMCID:: PMC3431934

Abstract Article PDF–5.6M

Select item 308403111.

Phosphoinositide [PI(3,5)P₂] lipid-dependent regulation of the general transcriptional regulator Tup1

Bong-Kwan Han, Scott D. Emr

Genes Dev. 2011 May 1; 25(9): 984–995. doi: 10.1101/gad.1998611

PMCID:: PMC3084031

Abstract Article PDF–1.0M

Select item 608071212.

PI(3,5)P₂ controls vacuole potassium transport to support cellular osmoregulation

Zachary N. Wilson, Amber L. Scott, Robin D. Dowell, Greg Odorizzi

Mol Biol Cell. 2018 Jul 15; 29(14): 1718–1731. doi: 10.1091/mbc.E18-01-0015

PMCID:: PMC6080712

Abstract Article PDF–1.9M

Select item 260065313.

VAC14 nucleates a protein complex essential for the acute interconversion of PI3P and PI(3,5)P₂ in yeast and mouse

Natsuko Jin, Clement Y Chow, Li Liu, Sergey N Zolov, Roderick Bronson, Muriel Davisson, Jason L Petersen, Yanling Zhang, Sujin Park, Jason E Duex, Daniel Goldowitz, Miriam H Meisler, Lois S Weisman

EMBO J. 2008 Dec 17; 27(24): 3221–3234. Published online 2008 Nov 27. doi: 10.1038/emboj.2008.248

PMCID:: PMC2600653

Abstract Article PDF–1.4M

Select item 396797914.

Roles for PI(3,5)P₂ in nutrient sensing through TORC1

Natsuko Jin, Kai Mao, Yui Jin, Gela Tevzadze, Emily J. Kauffman, Sujin Park, Dave Bridges, Robbie Loewith, Alan R. Saltiel, Daniel J. Klionsky, Lois S. Weisman

Mol Biol Cell. 2014 Apr 1; 25(7): 1171–1185. doi: 10.1091/mbc.E14-01-0021

PMCID:: PMC3967979

Abstract Article PDF–4.2M

Select item 195062015.

Efficient Tor Signaling Requires a Functional Class C Vps Protein Complex in Saccharomyces cerevisiae

Sara A. Zurita-Martinez, Rekha Puria, Xuewen Pan, Jef D. Boeke, Maria E. Cardenas

Genetics. 2007 Aug; 176(4): 2139–2150. doi: 10.1534/genetics.107.072835

PMCID:: PMC1950620

Abstract Article PDF–1.4M

Select item 435814116.

Differential Phosphorylation of a Regulatory Subunit of Protein Kinase CK2 by Target of Rapamycin Complex 1 Signaling and the Cdc-like Kinase Kns1

Manuel E. Sanchez-Casalongue, Jaehoon Lee, Aviva Diamond, Scott Shuldiner, Robyn D. Moir, Ian M. Willis

J Biol Chem. 2015 Mar 13; 290(11): 7221–7233. Published online 2015 Jan 28. doi: 10.1074/jbc.M114.626523

PMCID:: PMC4358141

Abstract Article PDF–2.1M

Select item 993052817.

SWR1 chromatin remodeling complex prevents mitotic slippage during spindle position checkpoint arrest

Ayse Koca Caydasi, Anton Khmelinskii, Zoulfia Darieva, Bahtiyar Kurtulmus, Michael Knop, Gislene Pereira

Mol Biol Cell. 2023 Feb 1; 34(2): ar11. Published online 2023 Jan 13. doi: 10.1091/mbc.E20-03-0179

PMCID:: PMC9930528

Abstract Article PDF–8.4M

Select item 782259418.

Cross-compartment signal propagation in the mitotic exit network

Xiaoxue Zhou, Wenxue Li, Yansheng Liu, Angelika Amon

eLife. 2021; 10: e63645. Published online 2021 Jan 22. doi: 10.7554/eLife.63645

PMCID:: PMC7822594

Abstract Article PDF–4.3M

Select item 675347119.

Rad5 dysregulation drives hyperactive recombination at replication forks resulting in cisplatin sensitivity and genome instability

Eric E Bryant, Ivana Šunjevarić, Luke Berchowitz, Rodney Rothstein, Robert J D Reid

Nucleic Acids Res. 2019 Sep 26; 47(17): 9144–9159. Published online 2019 Jul 27. doi: 10.1093/nar/gkz631

PMCID:: PMC6753471

Abstract Article PDF–6.0M

Select item 671577420.

Network Rewiring of Homologous Recombination Enzymes during Mitotic Proliferation and Meiosis

Philipp Wild, Aitor Susperregui, Ilaria Piazza, Christian Dörig, Ashwini Oke, Meret Arter, Miyuki Yamaguchi, Alexander T. Hilditch, Karla Vuina, Ki Choi Chan, Tatiana Gromova, James E. Haber, Jennifer C. Fung, Paola Picotti, Joao Matos

Mol Cell. 2019 Aug 22; 75(4): 859–874.e4. doi: 10.1016/j.molcel.2019.06.022

PMCID:: PMC6715774

Abstract Article

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