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Select item 30129991.

Functional Gene Expression Profiling in Yeast Implicates Translational Dysfunction in Mutant Huntingtin Toxicity

Eran Tauber, Leonor Miller-Fleming, Robert P. Mason, Wanda Kwan, Jannine Clapp, Nicola J. Butler, Tiago F. Outeiro, Paul J. Muchowski, Flaviano Giorgini

J Biol Chem. 2011 Jan 7; 286(1): 410–419. Published online 2010 Nov 2. doi: 10.1074/jbc.M110.101527

PMCID:: PMC3012999

Abstract Article PDF–1.2M

Select item 38808582.

Coupled GTPase and remodeling ATPase activities form a checkpoint for ribosome export

Yoshitaka Matsuo, Sander Granneman, Matthias Thoms, Rizos-Georgios Manikas, David Tollervey, Ed Hurt

Nature. Author manuscript; available in PMC 2014 Jul 2.

Published in final edited form as: Nature. 2014 Jan 2; 505(7481): 112–116. Published online 2013 Nov 17. doi: 10.1038/nature12731

PMCID:: PMC3880858

Abstract Article PDF–2.4M

Select item 75476903.

Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel

Daniel M. Wilson, Yu Li, Amber LaPeruta, Michael Gamalinda, Ning Gao, John L. Woolford, Jr

Nat Commun. 2020; 11: 5111. Published online 2020 Oct 9. doi: 10.1038/s41467-020-18878-8

PMCID:: PMC7547690

Abstract Article PDF–3.4M

Select item 28750174.

Analysis of ribosome biogenesis factor-modules in yeast cells depleted from pre-ribosomes

Juliane Merl, Steffen Jakob, Katrin Ridinger, Thomas Hierlmeier, Rainer Deutzmann, Philipp Milkereit, Herbert Tschochner

Nucleic Acids Res. 2010 May; 38(9): 3068–3080. Published online 2010 Jan 25. doi: 10.1093/nar/gkp1244

PMCID:: PMC2875017

Abstract Article PDF–3.9M

Select item 36780775.

Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel

Bettina Bradatsch, Christoph Leidig, Sander Granneman, Marén Gnädig, David Tollervey, Bettina Böttcher, Roland Beckmann, Ed Hurt

Nat Struct Mol Biol. Author manuscript; available in PMC 2013 Jun 11.

Published in final edited form as: Nat Struct Mol Biol. 2012 Dec; 19(12): 1234–1241. Published online 2012 Nov 11. doi: 10.1038/nsmb.2438

PMCID:: PMC3678077

Abstract Article PDF–3.4M

Select item 47702456.

The K⁺-dependent GTPase Nug1 is implicated in the association of the helicase Dbp10 to the immature peptidyl transferase centre during ribosome maturation

Rizos-Georgios Manikas, Emma Thomson, Matthias Thoms, Ed Hurt

Nucleic Acids Res. 2016 Feb 29; 44(4): 1800–1812. Published online 2016 Jan 28. doi: 10.1093/nar/gkw045

PMCID:: PMC4770245

Abstract Article PDF–7.0M

Select item 35105467.

The Conserved Bud20 Zinc Finger Protein Is a New Component of the Ribosomal 60S Subunit Export Machinery

Jochen Baßler, Isabella Klein, Claudia Schmidt, Martina Kallas, Emma Thomson, Maria Anna Wagner, Bettina Bradatsch, Gerald Rechberger, Heimo Strohmaier, Ed Hurt, Helmut Bergler

Mol Cell Biol. 2012 Dec; 32(24): 4898–4912. doi: 10.1128/MCB.00910-12

PMCID:: PMC3510546

Abstract Article PDF–3.3M

Select item 33728918.

The AAA-ATPase Rea1 Drives Removal of Biogenesis Factors during Multiple Stages of 60S Ribosome Assembly

Jochen Baßler, Martina Kallas, Brigitte Pertschy, Cornelia Ulbrich, Matthias Thoms, Ed Hurt

Mol Cell. Author manuscript; available in PMC 2012 Jun 12.

Published in final edited form as: Mol Cell. 2010 Jun 11; 38(5): 712–721. doi: 10.1016/j.molcel.2010.05.024

PMCID:: PMC3372891

Abstract Article PDF–1.6M

Select item 35419599.

TOR and RAS pathways regulate desiccation tolerance in Saccharomyces cerevisiae

Aaron Z. Welch, Patrick A. Gibney, David Botstein, Douglas E. Koshland

Mol Biol Cell. 2013 Jan 15; 24(2): 115–128. doi: 10.1091/mbc.E12-07-0524

PMCID:: PMC3541959

Abstract Article PDF–977K

Select item 275316810.

Yvh1 is required for a late maturation step in the 60S biogenesis pathway

Stefan Kemmler, Laura Occhipinti, Maria Veisu, Vikram Govind Panse

J Cell Biol. 2009 Sep 21; 186(6): 863–880. doi: 10.1083/jcb.200904111

PMCID:: PMC2753168

Abstract Article PDF–4.1M

Select item 498689411.

The N-terminal extension of yeast ribosomal protein L8 is involved in two major remodeling events during late nuclear stages of 60S ribosomal subunit assembly

Beril Tutuncuoglu, Jelena Jakovljevic, Shan Wu, Ning Gao, John L. Woolford, Jr.

RNA. 2016 Sep; 22(9): 1386–1399. doi: 10.1261/rna.055798.115

PMCID:: PMC4986894

Abstract Article PDF–1.9M

Select item 541682912.

The assembly factor Erb1 functions in multiple remodeling events during 60S ribosomal subunit assembly in S. cerevisiae

Salini Konikkat, Stephanie Biedka, John L. Woolford, Jr

Nucleic Acids Res. 2017 May 5; 45(8): 4853–4865. Published online 2017 Jan 23. doi: 10.1093/nar/gkw1361

PMCID:: PMC5416829

Abstract Article PDF–5.7M

Select item 1015402813.

Concurrent remodelling of nucleolar 60S subunit precursors by the Rea1 ATPase and Spb4 RNA helicase

Valentin Mitterer, Matthias Thoms, Robert Buschauer, Otto Berninghausen, Ed Hurt, Roland Beckmann

eLife. 2023; 12: e84877. Published online 2023 Mar 17. doi: 10.7554/eLife.84877

PMCID:: PMC10154028

Abstract Article PDF–9.4M

Select item 1089977914.

The RNA helicase Dbp10 coordinates assembly factor association with PTC maturation during ribosome biogenesis

Valentin Mitterer, Hussein Hamze, Natalia Kunowska, Ulrich Stelzl, Anthony K Henras, Ed Hurt

Nucleic Acids Res. 2024 Feb 28; 52(4): 1975–1987. Published online 2023 Dec 19. doi: 10.1093/nar/gkad1206

PMCID:: PMC10899779

Abstract Article PDF–1.6M

Select item 899413515.

Emergence of the primordial pre-60S from the 90S pre-ribosome

Sherif Ismail, Dirk Flemming, Matthias Thoms, José Vicente Gomes-Filho, Lennart Randau, Roland Beckmann, Ed Hurt

Cell Rep. 2022 Apr 5; 39(1): 110640. Published online 2022 Apr 5. doi: 10.1016/j.celrep.2022.110640

PMCID:: PMC8994135

Abstract Article

Select item 588816016.

Viewing pre-60S maturation at a minute’s timescale

Gertrude Zisser, Uli Ohmayer, Christina Mauerhofer, Valentin Mitterer, Isabella Klein, Gerald N Rechberger, Heimo Wolinski, Michael Prattes, Brigitte Pertschy, Philipp Milkereit, Helmut Bergler

Nucleic Acids Res. 2018 Apr 6; 46(6): 3140–3151. Published online 2017 Dec 27. doi: 10.1093/nar/gkx1293

PMCID:: PMC5888160

Abstract Article PDF–5.9M

Select item 12907917.

60S pre-ribosome formation viewed from assembly in the nucleolus until export to the cytoplasm

Tracy A. Nissan, Jochen Baßler, Elisabeth Petfalski, David Tollervey, Ed Hurt

EMBO J. 2002 Oct 15; 21(20): 5539–5547. doi: 10.1093/emboj/cdf547

PMCID:: PMC129079

Abstract Article PDF–388K

Select item 1063906118.

Yeast ribosome biogenesis factors Puf6 and Nog2 and ribosomal proteins uL2 and eL43 act in concert to facilitate the release of nascent large ribosomal subunits from the nucleolus

Amber J LaPeruta, Stefanie Hedayati, Jelena Micic, Fiona Fitzgerald, David Kim, Grace Oualline, John L Woolford

Nucleic Acids Res. 2023 Nov 10; 51(20): 11277–11290. Published online 2023 Oct 9. doi: 10.1093/nar/gkad794

PMCID:: PMC10639061

Abstract Article PDF–3.7M

Select item 782259419.

Cross-compartment signal propagation in the mitotic exit network

Xiaoxue Zhou, Wenxue Li, Yansheng Liu, Angelika Amon

eLife. 2021; 10: e63645. Published online 2021 Jan 22. doi: 10.7554/eLife.63645

PMCID:: PMC7822594

Abstract Article PDF–4.3M

Select item 370791520.

Studies on the Assembly Characteristics of Large Subunit Ribosomal Proteins in S. cerevisae

Uli Ohmayer, Michael Gamalinda, Martina Sauert, Julius Ossowski, Gisela Pöll, Jan Linnemann, Thomas Hierlmeier, Jorge Perez-Fernandez, Beril Kumcuoglu, Isabelle Leger-Silvestre, Marlène Faubladier, Joachim Griesenbeck, John Woolford, Herbert Tschochner, Philipp Milkereit

PLoS One. 2013; 8(7): e68412. Published online 2013 Jul 10. doi: 10.1371/journal.pone.0068412