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Select item 107465261.

Contribution of the yeast bi-chaperone system in the restoration of the RNA helicase Ded1 and translational activity under severe ethanol stress

Ryoko Ando, Yu Ishikawa, Yoshiaki Kamada, Shingo Izawa

J Biol Chem. 2023 Dec; 299(12): 105472. Published online 2023 Nov 17. doi: 10.1016/j.jbc.2023.105472

PMCID:: PMC10746526

Abstract Article PDF–3.4M

Select item 83156392.

G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p

Jun Gao, Zhaofeng Gao, Andrea A. Putnam, Alicia K. Byrd, Sarah L. Venus, John C. Marecki, Andrea D. Edwards, Haley M. Lowe, Eckhard Jankowsky, Kevin D. Raney

Chem Commun (Camb) 2021 Jul 27; 57(60): 7445–7448. Published online 2021 Jul 7. doi: 10.1039/d1cc01479j

PMCID:: PMC8315639

Abstract Article

Select item 79127333.

The In Silico Identification of Potential Members of the Ded1/DDX3 Subfamily of DEAD-Box RNA Helicases from the Protozoan Parasite Leishmania infantum and Their Analyses in Yeast

Molka Mokdadi, Yosser Zina Abdelkrim, Josette Banroques, Emmeline Huvelle, Rafeh Oualha, Hilal Yeter-Alat, Ikram Guizani, Mourad Barhoumi, N. Kyle Tanner

Genes (Basel) 2021 Feb; 12(2): 212. Published online 2021 Feb 1. doi: 10.3390/genes12020212

PMCID:: PMC7912733

Abstract Article PDF–2.6M

Select item 72378894.

Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production

Christiane Iserman, Christine Desroches Altamirano, Ceciel Jegers, Ulrike Friedrich, Taraneh Zarin, Anatol W. Fritsch, Matthäus Mittasch, Antonio Domingues, Lena Hersemann, Marcus Jahnel, Doris Richter, Ulf-Peter Guenther, Matthias W. Hentze, Alan M. Moses, Anthony A. Hyman, Günter Kramer, Moritz Kreysing, Titus M. Franzmann, Simon Alberti

Cell. 2020 May 14; 181(4): 818–831.e19. doi: 10.1016/j.cell.2020.04.009

PMCID:: PMC7237889

Abstract Article

Select item 64682435.

Mechanistic characterization of the DEAD-box RNA helicase Ded1 from yeast as revealed by a novel technique using single-molecule magnetic tweezers

Saurabh Raj, Debjani Bagchi, Jessica Valle Orero, Josette Banroques, N Kyle Tanner, Vincent Croquette

Nucleic Acids Res. 2019 Apr 23; 47(7): 3699–3710. Published online 2019 Feb 14. doi: 10.1093/nar/gkz057

PMCID:: PMC6468243

Abstract Article PDF–1.3M

Select item 62262656.

The helicase Ded1p controls use of near-cognate translation initiation codons in 5′UTRs

Ulf-Peter Guenther, David E. Weinberg, Meghan M. Zubradt, Frank A. Tedeschi, Brittany N. Stawicki, Leah L. Zagore, Gloria A. Brar, Donny D. Licatalosi, David P. Bartel, Jonathan S. Weissman, Eckhard Jankowsky

Nature. Author manuscript; available in PMC 2018 Dec 27.

Published in final edited form as: Nature. 2018 Jul; 559(7712): 130–134. Published online 2018 Jun 27. doi: 10.1038/s41586-018-0258-0

PMCID:: PMC6226265

Abstract Article PDF–3.0M

Select item 56936257.

Biochemical differences and similarities between the DEAD-box helicase orthologs DDX3X and Ded1p

Deepak Sharma, Andrea A. Putnam, Eckhard Jankowsky

J Mol Biol. Author manuscript; available in PMC 2018 Nov 24.

Published in final edited form as: J Mol Biol. 2017 Nov 24; 429(23): 3730–3742. Published online 2017 Oct 13. doi: 10.1016/j.jmb.2017.10.008

PMCID:: PMC5693625

Abstract Article PDF–836K

Select item 43337408.

Coordinated Function of Cellular DEAD-Box Helicases in Suppression of Viral RNA Recombination and Maintenance of Viral Genome Integrity

Chingkai Chuang, K. Reddisiva Prasanth, Peter D. Nagy

PLoS Pathog. 2015 Feb; 11(2): e1004680. Published online 2015 Feb 18. doi: 10.1371/journal.ppat.1004680

PMCID:: PMC4333740

Abstract Article PDF–2.0M

Select item 42116569.

DEAD-Box Helicase Proteins Disrupt RNA Tertiary Structure Through Helix Capture

Cynthia Pan, Jeffrey P. Potratz, Brian Cannon, Zachary B. Simpson, Jessica L. Ziehr, Pilar Tijerina, Rick Russell

PLoS Biol. 2014 Oct; 12(10): e1001981. Published online 2014 Oct 28. doi: 10.1371/journal.pbio.1001981

PMCID:: PMC4211656

Abstract Article PDF–826K

Select item 328098810.

A Co-Opted DEAD-Box RNA Helicase Enhances Tombusvirus Plus-Strand Synthesis

Nikolay Kovalev, Judit Pogany, Peter D. Nagy

PLoS Pathog. 2012 Feb; 8(2): e1002537. Published online 2012 Feb 16. doi: 10.1371/journal.ppat.1002537

PMCID:: PMC3280988

Abstract Article PDF–1.3M

Select item 242317011.

A Conserved Phenylalanine of Motif IV in Superfamily 2 Helicases Is Required for Cooperative, ATP-Dependent Binding of RNA Substrates in DEAD-Box Proteins

Josette Banroques, Olivier Cordin, Monique Doère, Patrick Linder, N. Kyle Tanner

Mol Cell Biol. 2008 May; 28(10): 3359–3371. Published online 2008 Mar 10. doi: 10.1128/MCB.01555-07

PMCID:: PMC2423170

Abstract Article PDF–1.1M

Select item 144089612.

Discriminatory RNP remodeling by the DEAD-box protein DED1

Heath A. Bowers, Patricia A. Maroney, Margaret E. Fairman, Berthold Kastner, Reinhard Lührmann, Timothy W. Nilsen, Eckhard Jankowsky

RNA. 2006 May; 12(5): 903–912. doi: 10.1261/rna.2323406

PMCID:: PMC1440896

Abstract Article PDF–406K

Select item 44978213.

The newly discovered Q motif of DEAD-box RNA helicases regulates RNA-binding and helicase activity

Olivier Cordin, N Kyle Tanner, Monique Doère, Patrick Linder, Josette Banroques

EMBO J. 2004 Jul 7; 23(13): 2478–2487. Published online 2004 Jun 17. doi: 10.1038/sj.emboj.7600272

PMCID:: PMC449782

Abstract Article PDF–225K

Select item 39037014.

Ded1p, a conserved DExD/H-box translation factor, can promote yeast L-A virus negative-strand RNA synthesis in vitro

Jean-Leon Chong, Ray-Yuan Chuang, Luh Tung, Tien-Hsien Chang

Nucleic Acids Res. 2004; 32(6): 2031–2038. Published online 2004 Apr 2. doi: 10.1093/nar/gkh519

PMCID:: PMC390370

Abstract Article PDF–160K

Select item 2716515.

A mutant allele of essential, general translation initiation factor DED1 selectively inhibits translation of a viral mRNA

Amine O. Noueiry, Jianbo Chen, Paul Ahlquist

Proc Natl Acad Sci U S A. 2000 Nov 21; 97(24): 12985–12990. Published online 2000 Nov 7. doi: 10.1073/pnas.240460897

PMCID:: PMC27165

Abstract Article PDF–310K

Select item 929845516.

Post-transcriptional regulation of ATG1 is a critical node that modulates autophagy during distinct nutrient stresses

Vikramjit Lahiri, Shree Padma Metur, Zehan Hu, Xinxin Song, Muriel Mari, Wayne D. Hawkins, Janakraj Bhattarai, Elizabeth Delorme-Axford, Fulvio Reggiori, Daolin Tang, Joern Dengjel, Daniel J. Klionsky

Autophagy. 2022; 18(7): 1694–1714. Published online 2021 Nov 26. doi: 10.1080/15548627.2021.1997305