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Select item 92381661.

PIK3R3, a regulatory subunit of PI3K, modulates ovarian cancer stem cells and ovarian cancer development and progression by integrative analysis

Eun Jung Sohn

BMC Cancer. 2022; 22: 708. Published online 2022 Jun 27. doi: 10.1186/s12885-022-09807-7

PMCID:: PMC9238166

Abstract Article PDF–4.1M

Select item 77540572.

Inhibition of exosomal miR‐24‐3p in diabetes restores angiogenesis and facilitates wound repair via targeting PIK3R3

Yan Xu, Liu Ouyang, Lei He, Yanzhen Qu, Yu Han, Deyu Duan

J Cell Mol Med. 2020 Dec; 24(23): 13789–13803. Published online 2020 Nov 3. doi: 10.1111/jcmm.15958

PMCID:: PMC7754057

Abstract Article PDF–3.3M

Select item 57903783.

PIK3R3 promotes chemotherapeutic sensitivity of colorectal cancer through PIK3R3/NF-kB/TP pathway

Sidikjan Ibrahim, Guodong Li, Fuqing Hu, Zhenlin Hou, Qianzhi Chen, Geng Li, Xuelai Luo, Junbo Hu, Yongdong Feng

Cancer Biol Ther. 2018; 19(3): 222–229. Published online 2018 Jan 25. doi: 10.1080/15384047.2017.1416936

PMCID:: PMC5790378

Abstract Article PDF–1.1M

Select item 34794154.

Genetic and bioinformatic analyses of the expression and function of PI3K regulatory subunit PIK3R3 in an Asian patient gastric cancer library

Jin Zhou, Geng Bo Chen, Yew Chung Tang, Rohit Anthony Sinha, Yonghui Wu, Chui Sun Yap, Guihua Wang, Junbo Hu, Xianmin Xia, Patrick Tan, Liang Kee Goh, Paul Michael Yen

BMC Med Genomics. 2012; 5: 34. Published online 2012 Aug 9. doi: 10.1186/1755-8794-5-34

PMCID:: PMC3479415

Abstract Article PDF–869K

Select item 34690645.

Blocking p55PIK signaling inhibits proliferation and induces differentiation of leukemia cells

G Wang, Y Deng, X Cao, S Lai, Y Tong, X Luo, Y Feng, X Xia, J Gong, J Hu

Cell Death Differ. 2012 Nov; 19(11): 1870–1879. Published online 2012 Jun 22. doi: 10.1038/cdd.2012.70

Correction in:: Cell Death Differ. 2014 Oct; 21(10): 1664.

PMCID:: PMC3469064

Abstract Article PDF–764K

Select item 110175396.

Circ_0044235 regulates the development of osteoarthritis by the modulation of miR-375/PIK3R3 axis

Wenjie Qian, Kai Mei, Lei Zhu, Ying Chu, Jinpeng Lv, Changjun Yun

J Orthop Surg Res. 2024; 19: 241. Published online 2024 Apr 15. doi: 10.1186/s13018-024-04694-z

PMCID:: PMC11017539

Abstract Article PDF–3.4M

Select item 82663307.

MiR-513b-5p represses autophagy during the malignant progression of hepatocellular carcinoma by targeting PIK3R3

Wei Jin, Yilei Liang, Shuyou Li, Guoxiang Lin, Haiying Liang, Zhenni Zhang, Weiming Zhang, Rongjun Nie

Aging (Albany NY) 2021 Jun 30; 13(12): 16072–16087. Published online 2021 Jun 13. doi: 10.18632/aging.203135

PMCID:: PMC8266330

Abstract Article PDF–2.2M

Select item 72924918.

P55PIK Regulates P53-Dependent Apoptosis in Cancer Cells by Interacting with P53 DNA-Specific Domain

Chaoxing Li, Wenwen Li, Xiyao Cheng, Dapeng Zhang, Xiang Sun, Jingjing Zhou, Yin Zhou, Yongqi Huang, Xianmin Xia, Qi Ma, Zhengding Su

Onco Targets Ther. 2020; 13: 5177–5190. Published online 2020 Jun 8. doi: 10.2147/OTT.S247200

PMCID:: PMC7292491

Abstract Article PDF–7.5M

Select item 48114669.

KIT over-expression by p55PIK-PI3K leads to Imatinib-resistance in patients with gastrointestinal stromal tumors

Senyan Lai, Guihua Wang, Xiaonian Cao, Xuelai Luo, Guoping Wang, Xianmin Xia, Junbo Hu, Jing Wang

Oncotarget. 2016 Jan 12; 7(2): 1367–1379. Published online 2015 Oct 22. doi: 10.18632/oncotarget.6011

PMCID:: PMC4811466

Abstract Article PDF–4.5M

Select item 475075410.

HOTAIR Promotes Proliferation, Migration, and Invasion of Ovarian Cancer SKOV3 Cells Through Regulating PIK3R3

Lijun Dong, Lina Hu

Med Sci Monit. 2016; 22: 325–331. Published online 2016 Jan 31. doi: 10.12659/MSM.894913

PMCID:: PMC4750754

Abstract Article PDF–1.6M

Select item 359114711.

p55PIK Transcriptionally Activated by MZF1 Promotes Colorectal Cancer Cell Proliferation

Yu Deng, Jing Wang, Guihua Wang, Yuan Jin, Xuelai Luo, Xianmin Xia, Jianping Gong, Junbo Hu

Biomed Res Int. 2013; 2013: 868131. Published online 2012 Dec 23. doi: 10.1155/2013/868131

PMCID:: PMC3591147

Abstract Article PDF–1.9M

Select item 1035821412.

PIK3R3 is upregulated in liver cancer and activates Akt signaling to control cancer growth by regulation of CDKN1C and SMC1A

Weidong Lin, Kunpeng Wang, Jinggang Mo, Liezhi Wang, Zhenshun Song, Hao Jiang, Cong Wang, Chong Jin

Cancer Med. 2023 Jul; 12(13): 14413–14425. Published online 2023 May 22. doi: 10.1002/cam4.6068

PMCID:: PMC10358214

Abstract Article PDF–19M

Select item 639749013.

HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3

Shanshan Dong, Ranran Wang, Hui Wang, Qi Ding, Xiao Zhou, Jing Wang, Keqiang Zhang, Ying Long, Shan Lu, Ting Hong, Huayi Ren, Kee Wong, Xiaowu Sheng, Yu Wang, Yong Zeng

J Exp Clin Cancer Res. 2019; 38: 110. Published online 2019 Mar 1. doi: 10.1186/s13046-019-1103-5

PMCID:: PMC6397490

Abstract Article PDF–6.5M

Select item 180200514.

Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma

Liliana Soroceanu, Samir Kharbanda, Ruihuan Chen, Robert H. Soriano, Ken Aldape, Anjan Misra, Jiping Zha, William F. Forrest, Janice M. Nigro, Zora Modrusan, Burt G. Feuerstein, Heidi S. Phillips

Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9): 3466–3471. Published online 2007 Feb 20. doi: 10.1073/pnas.0611271104

PMCID:: PMC1802005

Abstract Article PDF–2.5M

Select item 122042415.

Multiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translation.

X Xia, G Serrero

Biochem J. 1999 Aug 1; 341(Pt 3): 831–837.

PMCID:: PMC1220424

Summary PDF–169K

Select item 1101466416.

VHL governs m6A modification and PIK3R3 mRNA stability in clear cell renal cell carcinomas

Hyemin Lee, Li Zhuang, Boyi Gan

J Clin Invest. 2024 Apr 15; 134(8): e179560. Published online 2024 Apr 15. doi: 10.1172/JCI179560

PMCID:: PMC11014664

Abstract Article PDF–606K

Select item 579980117.

PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis

Xi Yang, Yinjia Fu, Fuqing Hu, Xuelai Luo, Junbo Hu, Guihua Wang

Exp Mol Med. 2018 Jan; 50(1): e431. Published online 2018 Jan 19. doi: 10.1038/emm.2017.243

PMCID:: PMC5799801

Abstract Article PDF–3.1M

Select item 529131818.

PI3Kδ and primary immunodeficiencies

Carrie L. Lucas, Anita Chandra, Sergey Nejentsev, Alison M. Condliffe, Klaus Okkenhaug

Nat Rev Immunol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Nat Rev Immunol. 2016 Nov; 16(11): 702–714. Published online 2016 Sep 12. doi: 10.1038/nri.2016.93

PMCID:: PMC5291318

Abstract Article PDF–1.8M

Select item 403272819.

Computational Analysis of mRNA Expression Profiles Identifies the ITG Family and PIK3R3 as Crucial Genes for Regulating Triple Negative Breast Cancer Cell Migration

Sukhontip Klahan, Mei-Shin Wu, Edward Hsi, Chi-Cheng Huang, Ming-Feng Hou, Wei-Chiao Chang

Biomed Res Int. 2014; 2014: 536591. Published online 2014 May 6. doi: 10.1155/2014/536591

PMCID:: PMC4032728

Abstract Article PDF–624K

Select item 284018420.

Pooled Analysis of Phosphatidylinositol 3-kinase Pathway Variants and Risk of Prostate Cancer

Stella Koutros, Fredrick R. Schumacher, Richard B. Hayes, Jing Ma, Wen-Yi Huang, Demetrius Albanes, Federico Canzian, Stephen J. Chanock, E. David Crawford, W. Ryan Diver, Heather Spencer Feigelson, Edward Giovanucci, Christopher A. Haiman, Brian E. Henderson, David J. Hunter, Rudolf Kaaks, Laurence N. Kolonel, Peter Kraft, Loïc Le Marchand, Elio Riboli, Afshan Siddiq, Mier J. Stampfer, Daniel O. Stram, Gilles Thomas, Ruth C. Travis, Michael J. Thun, Meredith Yeager, Sonja I. Berndt

Cancer Res. Author manuscript; available in PMC 2011 Mar 15.

Published in final edited form as: Cancer Res. 2010 Mar 15; 70(6): 2389–2396. Published online 2010 Mar 2. doi: 10.1158/0008-5472.CAN-09-3575

PMCID:: PMC2840184

Abstract Article PDF–326K

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