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Select item 101191481.

Variants in ATRIP are associated with breast cancer susceptibility in the Polish population and UK Biobank

Cezary Cybulski, Neda Zamani, Wojciech Kluźniak, Larissa Milano, Dominika Wokołorczyk, Klaudia Stempa, Helena Rudnicka, Shiyu Zhang, Maryam Zadeh, Tomasz Huzarski, Anna Jakubowska, Tadeusz Dębniak, Marcin Lener, Marek Szwiec, Paweł Domagała, Amir Abbas Samani, Steven Narod, Jacek Gronwald, Jean-Yves Masson, Jan Lubiński, Mohammad R. Akbari

Am J Hum Genet. 2023 Apr 6; 110(4): 648–662. Published online 2023 Mar 27. doi: 10.1016/j.ajhg.2023.03.002

PMCID:: PMC10119148

Abstract Article PDF–3.6M

Select item 36783882.

ATR signaling: more than meeting at the fork

Edward A. Nam, David Cortez

Biochem J. Author manuscript; available in PMC 2013 Jun 11.

Published in final edited form as: Biochem J. 2011 Jun 15; 436(3): 527–536. doi: 10.1042/BJ20102162

PMCID:: PMC3678388

Abstract Article PDF–1.1M

Select item 12894013.

Dimerization of the ATRIP Protein through the Coiled-Coil Motif and Its Implication to the Maintenance of Stalled Replication Forks

Eisuke Itakura, Isao Sawada, Akira Matsuura

Mol Biol Cell. 2005 Dec; 16(12): 5551–5562. doi: 10.1091/mbc.E05-05-0427

PMCID:: PMC1289401

Abstract Article PDF–763K

Select item 34934464.

Identification of the First ATRIP–Deficient Patient and Novel Mutations in ATR Define a Clinical Spectrum for ATR–ATRIP Seckel Syndrome

Tomoo Ogi, Sarah Walker, Tom Stiff, Emma Hobson, Siripan Limsirichaikul, Gillian Carpenter, Katrina Prescott, Mohnish Suri, Philip J. Byrd, Michiko Matsuse, Norisato Mitsutake, Yuka Nakazawa, Pradeep Vasudevan, Margaret Barrow, Grant S. Stewart, A. Malcolm R. Taylor, Mark O'Driscoll, Penny A. Jeggo

PLoS Genet. 2012 Nov; 8(11): e1002945. Published online 2012 Nov 8. doi: 10.1371/journal.pgen.1002945

PMCID:: PMC3493446

Abstract Article PDF–1.6M

Select item 29763995.

ATR and ATRIP Are Recruited to Herpes Simplex Virus Type 1 Replication Compartments Even though ATR Signaling Is Disabled

Kareem N. Mohni, Christine M. Livingston, David Cortez, Sandra K. Weller

J Virol. 2010 Dec; 84(23): 12152–12164. Published online 2010 Sep 22. doi: 10.1128/JVI.01643-10

PMCID:: PMC2976399

Abstract Article PDF–3.4M

Select item 18999716.

Function of a Conserved Checkpoint Recruitment Domain in ATRIP Proteins

Heather L. Ball, Mark R. Ehrhardt, Daniel A. Mordes, Gloria G. Glick, Walter J. Chazin, David Cortez

Mol Cell Biol. 2007 May; 27(9): 3367–3377. Published online 2007 Mar 5. doi: 10.1128/MCB.02238-06

PMCID:: PMC1899971

Abstract Article PDF–793K

Select item 13601817.

ATRIP OLIGOMERIZATION IS REQUIRED FOR ATR-DEPENDENT CHECKPOINT SIGNALING

Heather L. Ball, David Cortez

J Biol Chem. Author manuscript; available in PMC 2006 Feb 2.

Published in final edited form as: J Biol Chem. 2005 Sep 9; 280(36): 31390–31396. Published online 2005 Jul 15. doi: 10.1074/jbc.M504961200

PMCID:: PMC1360181

Abstract Article PDF–951K

Select item 13346808.

ATRIP associates with replication protein A-coated ssDNA through multiple interactions

Yuka Namiki, Lee Zou

Proc Natl Acad Sci U S A. 2006 Jan 17; 103(3): 580–585. Published online 2006 Jan 9. doi: 10.1073/pnas.0510223103

PMCID:: PMC1334680

Abstract Article PDF–404K

Select item 3214569.

Quaternary Structure of ATR and Effects of ATRIP and Replication Protein A on Its DNA Binding and Kinase Activities

Keziban Ünsal-Kaçmaz, Aziz Sancar

Mol Cell Biol. 2004 Feb; 24(3): 1292–1300. doi: 10.1128/MCB.24.3.1292-1300.2003

PMCID:: PMC321456

Abstract Article PDF–657K

Select item 315588510.

ATR Autophosphorylation as a Molecular Switch for Checkpoint Activation

Shizhou Liu, Bunsyo Shiotani, Mayurika Lahiri, Alexandre Maréchal, Alice Tse, Charles Chung Yun Leung, J. N. Mark Glover, Xiaohong H. Yang, Lee Zou

Mol Cell. Author manuscript; available in PMC 2012 Jul 22.

Published in final edited form as: Mol Cell. 2011 Jul 22; 43(2): 192–202. doi: 10.1016/j.molcel.2011.06.019

PMCID:: PMC3155885

Abstract Article PDF–3.4M

Select item 278077911.

Functional genomic screens identify CINP as a genome maintenance protein

Courtney A. Lovejoy, Xin Xu, Carol E. Bansbach, Gloria G. Glick, Runxiang Zhao, Fei Ye, Bianca M. Sirbu, Laura C. Titus, Yu Shyr, David Cortez

Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46): 19304–19309. Published online 2009 Nov 4. doi: 10.1073/pnas.0909345106

PMCID:: PMC2780779

Abstract Article PDF–1.8M

Select item 272829212.

CDK2-Dependent Phosphorylation of ATRIP Regulates the G2/M Checkpoint Response to DNA Damage

Jeremy S. Myers, Runxiang Zhao, Xin Xu, Amy-Joan L. Ham, David Cortez

Cancer Res. Author manuscript; available in PMC 2009 Aug 18.

Published in final edited form as: Cancer Res. 2007 Jul 15; 67(14): 6685–6690. doi: 10.1158/0008-5472.CAN-07-0495

PMCID:: PMC2728292

Abstract Article PDF–844K

Select item 225902913.

Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1

Sudhakar Sivasubramaniam, Xuemin Sun, Yen-Ru Pan, Shaohui Wang, Eva Y.-H.P. Lee

Genes Dev. 2008 Mar 1; 22(5): 587–600. doi: 10.1101/gad.1627708

PMCID:: PMC2259029

Abstract Article PDF–715K

Select item 878603714.

Differential roles of ATR and ATM in p53, Chk1, and histone H2AX phosphorylation in response to hyperoxia: ATR-dependent ATM activation

Amit Kulkarni, Kumuda C. Das

Am J Physiol Lung Cell Mol Physiol. Author manuscript; available in PMC 2022 Jan 24.

Published in final edited form as: Am J Physiol Lung Cell Mol Physiol. 2008 May; 294(5): L998–L1006. Published online 2008 Mar 14. doi: 10.1152/ajplung.00004.2008

PMCID:: PMC8786037

Abstract Article PDF–1.8M

Select item 654486415.

Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation

Vaughn Thada, David Cortez

J Biol Chem. 2019 May 24; 294(21): 8395–8402. Published online 2019 Apr 2. doi: 10.1074/jbc.RA119.008154

PMCID:: PMC6544864

Abstract Article PDF–2.0M

Select item 529500516.

Mec1/ATR, the Program Manager of Nucleic Acids Inc.

Wenyi Feng

Genes (Basel) 2017 Jan; 8(1): 10. Published online 2016 Dec 28. doi: 10.3390/genes8010010

PMCID:: PMC5295005

Abstract Article PDF–702K

Select item 475889617.

ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA

Hui Zhang, PamelaSara E. Head, Waaqo Daddacha, Seong-Hoon Park, Xingzhe Li, Yunfeng Pan, Matthew Z. Madden, Duc M. Duong, Maohua Xie, Bing Yu, Matthew D. Warren, Elaine A. Liu, Vishal R. Dhere, Chunyang Li, Ivan Pradilla, Mylin A. Torres, Ya Wang, William S. Dynan, Paul W. Doetsch, Xingming Deng, Nicholas T. Seyfried, David Gius, David S. Yu

Cell Rep. Author manuscript; available in PMC 2016 Mar 9.

Published in final edited form as: Cell Rep. 2016 Feb 16; 14(6): 1435–1447. Published online 2016 Feb 4. doi: 10.1016/j.celrep.2016.01.018

PMCID:: PMC4758896

Abstract Article PDF–1.0M

Select item 293390318.

Differential Dynamics of ATR-Mediated Checkpoint Regulators

Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits

J Nucleic Acids. 2010; 2010: 319142. Published online 2010 Aug 17. doi: 10.4061/2010/319142

PMCID:: PMC2933903

Abstract Article PDF–3.7M

Select item 292225619.

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

Jun-Hyuk Choi, Laura A. Lindsey-Boltz, Michael Kemp, Aaron C. Mason, Marc S. Wold, Aziz Sancar

Proc Natl Acad Sci U S A. 2010 Aug 3; 107(31): 13660–13665. Published online 2010 Jun 28. doi: 10.1073/pnas.1007856107

PMCID:: PMC2922256

Abstract Article PDF–1.4M

Select item 241858420.

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

Daniel A. Mordes, Gloria G. Glick, Runxiang Zhao, David Cortez

Genes Dev. 2008 Jun 1; 22(11): 1478–1489. doi: 10.1101/gad.1666208

PMCID:: PMC2418584

Abstract Article PDF–470K

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