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Select item 54781851.

The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

Florian Weinberg, Nadine Reischmann, Lisa Fauth, Sanaz Taromi, Justin Mastroianni, Martin Köhler, Sebastian Halbach, Andrea C. Becker, Niantao Deng, Tatjana Schmitz, Franziska Maria Uhl, Nicola Herbener, Bianca Riedel, Fabian Beier, Alexander Swarbrick, Silke Lassmann, Jörn Dengjel, Robert Zeiser, Tilman Brummer

EBioMedicine. 2017 Jun; 20: 79–97. Published online 2017 Apr 12. doi: 10.1016/j.ebiom.2017.04.015

PMCID:: PMC5478185

Article PDF–4.6M

Select item 52900662.

Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1

Konrad Kubiński, Maciej Masłyk, Andrzej Orzeszko

Mol Cell Biochem. 2017; 426(1): 195–203. Published online 2016 Dec 1. doi: 10.1007/s11010-016-2892-x

PMCID:: PMC5290066

Article PDF–1.3M

Select item 81128633.

The final step of 40S ribosomal subunit maturation is controlled by a dual key lock

Laura Plassart, Ramtin Shayan, Christian Montellese, Dana Rinaldi, Natacha Larburu, Carole Pichereaux, Carine Froment, Simon Lebaron, Marie-Françoise O'Donohue, Ulrike Kutay, Julien Marcoux, Pierre-Emmanuel Gleizes, Celia Plisson-Chastang

eLife. 2021; 10: e61254. Published online 2021 Apr 28. doi: 10.7554/eLife.61254

PMCID:: PMC8112863

Article PDF–2.5M

Select item 75778034.

Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression

Zhiqi Huang, Xingyu Li, Tian Xie, Changjiang Gu, Kan Ni, Qingqing Yin, Xiaolei Cao, Chunhui Zhang

Cancer Res Treat. 2020 Oct; 52(4): 1067–1083. Published online 2020 May 8. doi: 10.4143/crt.2020.187

PMCID:: PMC7577803

Article PDF–3.7M

Select item 110327675.

Characterisation of tumour-associated antigens in colon cancer

Aija Line, Zane Slucka, Aivars Stengrevics, Karina Silina, Geng Li, Robert C. Rees

Cancer Immunol Immunother. 2002 Nov; 51(10): 574–582. Published online 2002 Sep 19. doi: 10.1007/s00262-002-0322-2

PMCID:: PMC11032767

Article PDF–351K

Select item 41177706.

Dominant Rio1 kinase/ATPase catalytic mutant induces trapping of late pre-40S biogenesis factors in 80S-like ribosomes

Sébastien Ferreira-Cerca, Irene Kiburu, Emma Thomson, Nicole LaRonde, Ed Hurt

Nucleic Acids Res. 2014 Sep 1; 42(13): 8635–8647. Published online 2014 Jun 21. doi: 10.1093/nar/gku542

PMCID:: PMC4117770

Article PDF–3.2M

Select item 32489007.

The kinase activity of human Rio1 is required for final steps of cytoplasmic maturation of 40S subunits

Barbara Widmann, Franziska Wandrey, Lukas Badertscher, Emanuel Wyler, Jens Pfannstiel, Ivo Zemp, Ulrike Kutay

Mol Biol Cell. 2012 Jan 1; 23(1): 22–35. doi: 10.1091/mbc.E11-07-0639

PMCID:: PMC3248900

Article PDF–7.8M

Select item 82520688.

Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5–MEP50 Complex

Adrian Krzyzanowski, Dr. Raphael Gasper, Dr. Hélène Adihou, Dr. Peter 't Hart, Prof. Dr. Herbert Waldmann

Chembiochem. 2021 Jun 2; 22(11): 1908–1914. Published online 2021 Mar 31. doi: 10.1002/cbic.202100079

PMCID:: PMC8252068

Article PDF–2.0M

Select item 35730979.

A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma

Renee D. Read, Tim R. Fenton, German G. Gomez, Jill Wykosky, Scott R. Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K. Cavenee, Paul S. Mischel, Frank B. Furnari, John B. Thomas

PLoS Genet. 2013 Feb; 9(2): e1003253. Published online 2013 Feb 14. doi: 10.1371/journal.pgen.1003253

PMCID:: PMC3573097

Article PDF–11M

Select item 581585310.

Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers

Xuehui Hong, He Huang, Xingfeng Qiu, Zhijie Ding, Xing Feng, Yuekun Zhu, Huiqin Zhuo, Jingjing Hou, Jiabao Zhao, Wangyu Cai, Ruihua Sha, Xinya Hong, Yongxiang Li, Hongjiang Song, Zhiyong Zhang

eLife. 2018; 7: e29511. Published online 2018 Jan 31. doi: 10.7554/eLife.29511

PMCID:: PMC5815853

Article PDF–6.9M

Select item 986728211.

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly

Sergi Rodriguez-Calado, Petra Van Damme, Francesc Xavier Avilés, Ana Paula Candiota, Sebastian Tanco, Julia Lorenzo

Int J Mol Sci. 2023 Jan; 24(2): 1273. Published online 2023 Jan 9. doi: 10.3390/ijms24021273

PMCID:: PMC9867282

Article PDF–2.5M

Select item 576815012.

MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B^DCAF13 E3 Ligase in Osteosarcoma Cells

Zhi Chen, Wei Zhang, Kaibiao Jiang, Bin Chen, Kun Wang, Lifeng Lao, Canglong Hou, Fei Wang, Caiguo Zhang, Hongxing Shen

Mol Ther Nucleic Acids. 2018 Mar 2; 10: 254–268. Published online 2017 Dec 22. doi: 10.1016/j.omtn.2017.12.010

PMCID:: PMC5768150

Article PDF–2.7M

Select item 979439413.

Nonstructural protein 1 widespread RNA decay phenotype varies among coronaviruses

Yahaira Bermudez, Jacob Miles, Mandy Muller

iScience. 2023 Jan 20; 26(1): 105887. Published online 2022 Dec 28. doi: 10.1016/j.isci.2022.105887

PMCID:: PMC9794394

Article PDF–2.6M

Select item 972361914.

The nucleoplasmic phase of pre-40S formation prior to nuclear export

Jingdong Cheng, Benjamin Lau, Matthias Thoms, Michael Ameismeier, Otto Berninghausen, Ed Hurt, Roland Beckmann

Nucleic Acids Res. 2022 Nov 11; 50(20): 11924–11937. Published online 2022 Nov 2. doi: 10.1093/nar/gkac961

PMCID:: PMC9723619

Article PDF–11M

Select item 440166215.

FBXW7 modulates cellular stress response and metastatic potential via HSF1 post-translational modification

Nikos Kourtis, Rana S. Moubarak, Beatriz Aranda-Orgilles, Kevin Lui, Iraz T. Aydin, Thomas Trimarchi, Farbod Darvishian, Christine Salvaggio, Judy Zhong, Kamala Bhatt, Emily I. Chen, Julide T. Celebi, Charalampos Lazaris, Aristotelis Tsirigos, Iman Osman, Eva Hernando, Iannis Aifantis

Nat Cell Biol. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Cell Biol. 2015 Mar; 17(3): 322–332. doi: 10.1038/ncb3121

PMCID:: PMC4401662

Article PDF–5.0M

Select item 488903016.

Glutamine triggers acetylation-dependent degradation of glutamine synthetase via the thalidomide receptor cereblon

Thang Van Nguyen, J. Eugene Lee, Michael J. Sweredoski, Seung-Joo Yang, Seung-Je Jeon, Joseph S. Harrison, Jung-Hyuk Yim, Sang Ghil Lee, Hiroshi Handa, Brian Kuhlman, Ji-Seon Jeong, Justin M. Reitsma, Chul-Seung Park, Sonja Hess, Raymond J. Deshaies

Mol Cell. Author manuscript; available in PMC 2017 Mar 17.

Published in final edited form as: Mol Cell. 2016 Mar 17; 61(6): 809–820. doi: 10.1016/j.molcel.2016.02.032

PMCID:: PMC4889030

Article PDF–2.3M

Select item 927116817.

C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways

David R. Amici, Daniel J. Ansel, Kyle A. Metz, Roger S. Smith, Claire M. Phoumyvong, Sitaram Gayatri, Tomasz Chamera, Stacey L. Edwards, Brendan P. O’Hara, Shashank Srivastava, Sonia Brockway, Seesha R. Takagishi, Byoung-Kyu Cho, Young Ah Goo, Neil L. Kelleher, Issam Ben-Sahra, Daniel R. Foltz, Jian Li, Marc L. Mendillo

Proc Natl Acad Sci U S A. 2022 Jul 5; 119(27): e2111262119. Published online 2022 Jul 1. doi: 10.1073/pnas.2111262119

PMCID:: PMC9271168

Article PDF–2.6M

Select item 533550618.

Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage

Hongli An, Lu Yang, Chen Wang, Zhixue Gan, Haihui Gu, Tao Zhang, Xin Huang, Yan Liu, Yufeng Li, Shing-Jyh Chang, Jianghua Lai, Ya-Bin Li, Su Chen, Fang-Lin Sun

Mol Cell Biol. 2017 Mar 15; 37(6): e00419-16. Prepublished online 2016 Dec 28. Published online 2017 Mar 1. doi: 10.1128/MCB.00419-16

PMCID:: PMC5335506

Article PDF–4.8M

Select item 573721819.

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer

Madhumitha Rengasamy, Fan Zhang, Ajay Vashisht, Won-Min Song, Francesca Aguilo, Yifei Sun, SiDe Li, Weijia Zhang, Bin Zhang, James A. Wohlschlegel, Martin J. Walsh

Nucleic Acids Res. 2017 Nov 2; 45(19): 11106–11120. Published online 2017 Aug 21. doi: 10.1093/nar/gkx727

PMCID:: PMC5737218

Article PDF–4.1M

Select item 451071120.

RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway

Yasuhiro Murakawa, Michael Hinz, Janina Mothes, Anja Schuetz, Michael Uhl, Emanuel Wyler, Tomoharu Yasuda, Guido Mastrobuoni, Caroline C. Friedel, Lars Dölken, Stefan Kempa, Marc Schmidt-Supprian, Nils Blüthgen, Rolf Backofen, Udo Heinemann, Jana Wolf, Claus Scheidereit, Markus Landthaler

Nat Commun. 2015; 6: 7367. Published online 2015 Jul 14. doi: 10.1038/ncomms8367