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Items: 1 to 20 of 24

1.
Bi-allelic variants in DOHH, catalyzing the last step of hypusine biosynthesis, are associated with a neurodevelopmental disorder
Alban Ziegler, Katharina Steindl, Ashleigh S. Hanner, Rajesh Kumar Kar, Clément Prouteau, Anne Boland, Jean Francois Deleuze, Christine Coubes, Stéphane Bézieau, Sébastien Küry, Isabelle Maystadt, Morgane Le Mao, Guy Lenaers, Benjamin Navet, Laurence Faivre, Frédéric Tran Mau-Them, Paolo Zanoni, Wendy K. Chung, Anita Rauch, Dominique Bonneau, Myung Hee Park
Am J Hum Genet. 2022 Aug 4; 109(8): 1549–1558. Published online 2022 Jul 19. doi: 10.1016/j.ajhg.2022.06.010
PMCID:
PMC9388783
ArticlePDF–1.5M
2.
Regulation of Expression of Deoxyhypusine Hydroxylase (DOHH), the Enzyme That Catalyzes the Activation of eIF5A, by miR-331-3p and miR-642-5p in Prostate Cancer Cells
Michael R. Epis, Keith M. Giles, Felicity C. Kalinowski, Andrew Barker, Ronald J. Cohen, Peter J. Leedman
J Biol Chem. 2012 Oct 12; 287(42): 35251–35259. Published online 2012 Aug 20. doi: 10.1074/jbc.M112.374686
PMCID:
PMC3471734
ArticlePDF–797K
3.
Human deoxyhypusine hydroxylase, an enzyme involved in regulating cell growth, activates O2 with a nonheme diiron center
Van V. Vu, Joseph P. Emerson, Marlène Martinho, Yeon Sook Kim, Eckard Münck, Myung Hee Park, Lawrence Que, Jr
Proc Natl Acad Sci U S A. 2009 Sep 1; 106(35): 14814–14819. Published online 2009 Aug 19. doi: 10.1073/pnas.0904553106
PMCID:
PMC2736468
ArticlePDF–1.0M
4.
Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification
E. C. Wolff, K. R. Kang, Y. S. Kim, M. H. Park
Amino Acids. Author manuscript; available in PMC 2008 Oct 27.
Published in final edited form as: Amino Acids. 2007 Aug; 33(2): 341–350. Published online 2007 May 4. doi: 10.1007/s00726-007-0525-0
PMCID:
PMC2572820
ArticlePDF–1.2M
5.
DEOXYHYPUSINE HYDROXYLASE IS A Fe(II)-DEPENDENT, HEAT-REPEAT ENZYME: IDENTIFICATION OF AMINO ACID RESIDUES CRITICAL FOR Fe(II) BINDING AND CATALYSIS
Yeon Sook Kim, Kee Ryeon Kang, Edith C. Wolff, Jessica K. Bell, Peter McPhie, Myung Hee Park
J Biol Chem. Author manuscript; available in PMC 2007 May 16.
Published in final edited form as: J Biol Chem. 2006 May 12; 281(19): 13217–13225. Published online 2006 Mar 13. doi: 10.1074/jbc.M601081200
Correction in:
J Biol Chem, volume 282 on page 10840
PMCID:
PMC1868894
ArticlePDF–558K
6.
Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase
Avery G. Frey, Anjali Nandal, Jong Hwan Park, Pamela M. Smith, Toshiki Yabe, Moon-Suhn Ryu, Manik C. Ghosh, Jaekwon Lee, Tracey A. Rouault, Myung Hee Park, Caroline C. Philpott
Proc Natl Acad Sci U S A. 2014 Jun 3; 111(22): 8031–8036. Published online 2014 May 19. doi: 10.1073/pnas.1402732111
PMCID:
PMC4050543
ArticlePDF–832K
7.
Specificity of the deoxyhypusine hydroxylase-eIF5A interaction: Identification of amino acid residues of the enzyme required for binding of its substrate, deoxyhypusine-containing eIF5A
Kee Ryeon Kang, Yeon Sook Kim, Edith C. Wolff, Myung Hee Park
J Biol Chem. Author manuscript; available in PMC 2007 Apr 17.
Published in final edited form as: J Biol Chem. 2007 Mar 16; 282(11): 8300–8308. Published online 2007 Jan 9. doi: 10.1074/jbc.M607495200
PMCID:
PMC1852541
ArticlePDF–487K
8.
Expression of Eukaryotic Initiation Factor 5A and Hypusine Forming Enzymes in Glioblastoma Patient Samples: Implications for New Targeted Therapies
Michael Preukschas, Christian Hagel, Alexander Schulte, Kristoffer Weber, Katrin Lamszus, Henning Sievert, Nora Pällmann, Carsten Bokemeyer, Joachim Hauber, Melanie Braig, Stefan Balabanov
PLoS One. 2012; 7(8): e43468. Published online 2012 Aug 21. doi: 10.1371/journal.pone.0043468
PMCID:
PMC3424167
ArticlePDF–5.4M
9.
The Post-Translational Synthesis of a Polyamine-Derived Amino Acid, Hypusine, in the Eukaryotic Translation Initiation Factor 5A (eIF5A)
Myung Hee Park
J Biochem. Author manuscript; available in PMC 2008 Aug 4.
Published in final edited form as: J Biochem. 2006 Feb; 139(2): 161–169. doi: 10.1093/jb/mvj034
PMCID:
PMC2494880
ArticlePDF–2.4M
10.
Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: A HEAT-repeat-containing metalloenzyme
Jong-Hwan Park, L. Aravind, Edith C. Wolff, Jörn Kaevel, Yeon Sook Kim, Myung Hee Park
Proc Natl Acad Sci U S A. 2006 Jan 3; 103(1): 51–56. Published online 2005 Dec 21. doi: 10.1073/pnas.0509348102
PMCID:
PMC1324997
ArticlePDF–690K
11.
The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2
Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue
Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600
PMCID:
PMC9475453
ArticlePDF–4.4M
12.
Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity
Ying Chen, Li-Na Yang, Li Cheng, Shun Tu, Shu-Juan Guo, Huang-Ying Le, Qian Xiong, Ran Mo, Chong-Yang Li, Jun-Seop Jeong, Lizhi Jiang, Seth Blackshaw, Li-Jun Bi, Heng Zhu, Sheng-Ce Tao, Feng Ge
Mol Cell Proteomics. 2013 Oct; 12(10): 2804–2819. Published online 2013 Jul 3. doi: 10.1074/mcp.M112.025882
PMCID:
PMC3790292
ArticlePDF–2.6M
13.
Global landscape of HIV–human protein complexes
Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Ivan D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel, Nevan J. Krogan
Nature. Author manuscript; available in PMC 2013 Jan 19.
Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 365–370. Published online 2011 Dec 21. doi: 10.1038/nature10719
PMCID:
PMC3310911
ArticlePDF–1.8M
14.
BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression
Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee, Tomonori Hosoya, Qingqing Wu, Greggory Myers, Kim-Chew Lim, Ryo Kurita, Yukio Nakamura, Anne B. Vojtek, Jean-François Rual, James Douglas Engel
Genes Dev. 2018 Dec 1; 32(23-24): 1537–1549. doi: 10.1101/gad.318436.118
PMCID:
PMC6295165
ArticlePDF–3.5M
15.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
ArticlePDF–4.5M
16.
PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling
Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin
Cell Rep. Author manuscript; available in PMC 2019 Jun 26.
Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060
PMCID:
PMC6594551
ArticlePDF–1.4M
17.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
ArticlePDF–4.7M
18.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
ArticlePDF–23M
19.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
ArticlePDF–2.2M
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
ArticlePDF–2.7M

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