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Select item 105019071.

Multi-cancer analysis reveals universal association of oncogenic LBH expression with DNA hypomethylation and WNT-Integrin signaling pathways

In-Chi Young, Thomas Brabletz, Linsey E. Lindley, Maria Abreu, Nagaraj Nagathihalli, Alexander Zaika, Karoline J. Briegel

Cancer Gene Ther. 2023; 30(9): 1234–1248. Published online 2023 Jun 2. doi: 10.1038/s41417-023-00633-y

PMCID:: PMC10501907

Abstract Article PDF–9.1M

Select item 50831312.

Limb Bud and Heart Development Gene Transcription is Regulated by the Interplay of an Enhancer Risk Allele and DNA Methylation in Rheumatoid Arthritis

Deepa Hammaker, John W. Whitaker, Keisuke Maeshima, David L. Boyle, Anna-Karin H. Ekwall, Wei Wang, Gary S. Firestein

Arthritis Rheumatol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Arthritis Rheumatol. 2016 Nov; 68(11): 2637–2645. doi: 10.1002/art.39746

PMCID:: PMC5083131

Abstract Article PDF–1.1M

Select item 44909333.

The Rheumatoid Arthritis Risk Gene LBH Regulates Growth in Fibroblast-like Synoviocytes

Anna-Karin H. Ekwall, John W. Whitaker, Deepa Hammaker, William D. Bugbee, Wei Wang, Gary S. Firestein

Arthritis Rheumatol. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: Arthritis Rheumatol. 2015 May; 67(5): 1193–1202. doi: 10.1002/art.39060

PMCID:: PMC4490933

Abstract Article PDF–1.5M

Select item 42838264.

Limb-bud and Heart (LBH) Functions as a Tumor Suppressor of Nasopharyngeal Carcinoma by Inducing G1/S Cell Cycle Arrest

Qicai Liu, Xiaoying Guan, Jingli Lv, Xiaoyan Li, Yingfeng Wang, Li Li

Sci Rep. 2015; 5: 7626. Published online 2015 Jan 5. doi: 10.1038/srep07626

PMCID:: PMC4283826

Abstract Article PDF–3.7M

Select item 86921475.

Exosomal LBH inhibits epithelial-mesenchymal transition and angiogenesis in nasopharyngeal carcinoma via downregulating VEGFA signaling

Anbiao Wu, Ning Luo, Yuling Xu, Nan Du, Li Li, Qicai Liu

Int J Biol Sci. 2022; 18(1): 242–260. Published online 2022 Jan 1. doi: 10.7150/ijbs.66506

PMCID:: PMC8692147

Abstract Article PDF–5.7M

Select item 83950366.

LncRNA MIR31HG Drives Oncogenicity by Inhibiting the Limb-Bud and Heart Development Gene (LBH) during Oral Carcinoma

Kuo-Wei Chang, Wan-Wen Hung, Chung-Hsien Chou, Hsi-Feng Tu, Shi-Rou Chang, Ying-Chieh Liu, Chung-Ji Liu, Shu-Chun Lin

Int J Mol Sci. 2021 Aug; 22(16): 8383. Published online 2021 Aug 4. doi: 10.3390/ijms22168383

PMCID:: PMC8395036

Abstract Article PDF–3.5M

Select item 29375477.

The Embryonic Transcription Cofactor LBH Is a Direct Target of the Wnt Signaling Pathway in Epithelial Development and in Aggressive Basal Subtype Breast Cancers

Megan E. Rieger, Andrew H. Sims, Ebony R. Coats, Robert B. Clarke, Karoline J. Briegel

Mol Cell Biol. 2010 Sep; 30(17): 4267–4279. Published online 2010 Jul 6. doi: 10.1128/MCB.01418-09

PMCID:: PMC2937547

Abstract Article PDF–2.6M

Select item 30446858.

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

Alexandra Zhernakova, Eli A. Stahl, Gosia Trynka, Soumya Raychaudhuri, Eleanora A. Festen, Lude Franke, Harm-Jan Westra, Rudolf S. N. Fehrmann, Fina A. S. Kurreeman, Brian Thomson, Namrata Gupta, Jihane Romanos, Ross McManus, Anthony W. Ryan, Graham Turner, Elisabeth Brouwer, Marcel D. Posthumus, Elaine F. Remmers, Francesca Tucci, Rene Toes, Elvira Grandone, Maria Cristina Mazzilli, Anna Rybak, Bozena Cukrowska, Marieke J. H. Coenen, Timothy R. D. J. Radstake, Piet L. C. M. van Riel, Yonghong Li, Paul I. W. de Bakker, Peter K. Gregersen, Jane Worthington, Katherine A. Siminovitch, Lars Klareskog, Tom W. J. Huizinga, Cisca Wijmenga, Robert M. Plenge

PLoS Genet. 2011 Feb; 7(2): e1002004. Published online 2011 Feb 24. doi: 10.1371/journal.pgen.1002004

PMCID:: PMC3044685

Abstract Article PDF–421K

Select item 31635149.

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels

Guillemette Antoni, Tiphaine Oudot-Mellakh, Apostolos Dimitromanolakis, Marine Germain, William Cohen, Philip Wells, Mark Lathrop, France Gagnon, Pierre-Emmanuel Morange, David-Alexandre Tregouet

BMC Med Genet. 2011; 12: 102. Published online 2011 Aug 2. doi: 10.1186/1471-2350-12-102

PMCID:: PMC3163514

Abstract Article PDF–303K

Select item 648550710.

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

Iain C. Macaulay, Marloes R. Tijssen, Daphne C. Thijssen-Timmer, Arief Gusnanto, Michael Steward, Philippa Burns, Cordelia F. Langford, Peter D. Ellis, Frank Dudbridge, Jaap-Jan Zwaginga, Nicholas A. Watkins, C. Ellen van der Schoot, Willem H. Ouwehand

Blood. Author manuscript; available in PMC 2019 Apr 26.

Published in final edited form as: Blood. 2007 Apr 15; 109(8): 3260–3269. Published online 2006 Dec 27. doi: 10.1182/blood-2006-07-036269

PMCID:: PMC6485507

Abstract Article PDF–4.4M

Select item 289479011.

The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature

Jianhua Zhao, Mingyao Li, Jonathan P Bradfield, Haitao Zhang, Frank D Mentch, Kai Wang, Patrick M Sleiman, Cecilia E Kim, Joseph T Glessner, Cuiping Hou, Brendan J Keating, Kelly A Thomas, Maria L Garris, Sandra Deliard, Edward C Frackelton, F George Otieno, Rosetta M Chiavacci, Robert I Berkowitz, Hakon Hakonarson, Struan FA Grant

BMC Med Genet. 2010; 11: 96. Published online 2010 Jun 14. doi: 10.1186/1471-2350-11-96

PMCID:: PMC2894790

Abstract Article PDF–803K

Select item 394409812.

Genetics of rheumatoid arthritis contributes to biology and drug discovery

Yukinori Okada, Di Wu, Gosia Trynka, Towfique Raj, Chikashi Terao, Katsunori Ikari, Yuta Kochi, Koichiro Ohmura, Akari Suzuki, Shinji Yoshida, Robert R. Graham, Arun Manoharan, Ward Ortmann, Tushar Bhangale, Joshua C. Denny, Robert J. Carroll, Anne E. Eyler, Jeffrey D. Greenberg, Joel M. Kremer, Dimitrios A. Pappas, Lei Jiang, Jian Yin, Lingying Ye, Ding-Feng Su, Jian Yang, Gang Xie, Ed Keystone, Harm-Jan Westra, Tõnu Esko, Andres Metspalu, Xuezhong Zhou, Namrata Gupta, Daniel Mirel, Eli A. Stahl, Dorothée Diogo, Jing Cui, Katherine Liao, Michael H. Guo, Keiko Myouzen, Takahisa Kawaguchi, Marieke J.H. Coenen, Piet L.C.M. van Riel, Mart A.F.J. van de Laar, Henk-Jan Guchelaar, Tom W.J. Huizinga, Philippe Dieudé, Xavier Mariette, S. Louis Bridges, Jr., Alexandra Zhernakova, Rene E.M. Toes, Paul P. Tak, Corinne Miceli-Richard, So-Young Bang, Hye-Soon Lee, Javier Martin, Miguel A. Gonzalez-Gay, Luis Rodriguez-Rodriguez, Solbritt Rantapää-Dahlqvist, Lisbeth Ärlestig, Hyon K. Choi, Yoichiro Kamatani, Pilar Galan, Mark Lathrop, the RACI consortium, the GARNET consortium, Steve Eyre, John Bowes, Anne Barton, Niek de Vries, Larry W. Moreland, Lindsey A. Criswell, Elizabeth W. Karlson, Atsuo Taniguchi, Ryo Yamada, Michiaki Kubo, Jun S. Liu, Sang-Cheol Bae, Jane Worthington, Leonid Padyukov, Lars Klareskog, Peter K. Gregersen, Soumya Raychaudhuri, Barbara E. Stranger, Philip L. De Jager, Lude Franke, Peter M. Visscher, Matthew A. Brown, Hisashi Yamanaka, Tsuneyo Mimori, Atsushi Takahashi, Huji Xu, Timothy W. Behrens, Katherine A. Siminovitch, Shigeki Momohara, Fumihiko Matsuda, Kazuhiko Yamamoto, Robert M. Plenge

Nature. Author manuscript; available in PMC 2014 Aug 20.

Published in final edited form as: Nature. 2014 Feb 20; 506(7488): 376–381. Published online 2013 Dec 25. doi: 10.1038/nature12873

PMCID:: PMC3944098

Abstract Article PDF–1.9M

Select item 134750113.

The LIFEdb database in 2006

Alexander Mehrle, Heiko Rosenfelder, Ingo Schupp, Coral del Val, Dorit Arlt, Florian Hahne, Stephanie Bechtel, Jeremy Simpson, Oliver Hofmann, Winston Hide, Karl-Heinz Glatting, Wolfgang Huber, Rainer Pepperkok, Annemarie Poustka, Stefan Wiemann

Nucleic Acids Res. 2006 Jan 1; 34(Database issue): D415–D418. Published online 2005 Dec 28. doi: 10.1093/nar/gkj139

PMCID:: PMC1347501

Abstract Article PDF–301K

Select item 52893014.

From ORFeome to Biology: A Functional Genomics Pipeline

Stefan Wiemann, Dorit Arlt, Wolfgang Huber, Ruth Wellenreuther, Simone Schleeger, Alexander Mehrle, Stephanie Bechtel, Mamatha Sauermann, Ulrike Korf, Rainer Pepperkok, Holger Sültmann, Annemarie Poustka

Genome Res. 2004 Oct; 14(10b): 2136–2144. doi: 10.1101/gr.2576704

PMCID:: PMC528930

Abstract Article PDF–459K

Select item 31107215.

Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs

Stefan Wiemann, Bernd Weil, Ruth Wellenreuther, Johannes Gassenhuber, Sabine Glassl, Wilhelm Ansorge, Michael Böcher, Helmut Blöcker, Stefan Bauersachs, Helmut Blum, Jürgen Lauber, Andreas Düsterhöft, Andreas Beyer, Karl Köhrer, Normann Strack, Hans-Werner Mewes, Birgit Ottenwälder, Brigitte Obermaier, Jens Tampe, Dagmar Heubner, Rolf Wambutt, Bernhard Korn, Michaela Klein, Annemarie Poustka

Genome Res. 2001 Mar; 11(3): 422–435. doi: 10.1101/gr.154701

PMCID:: PMC311072

Abstract Article PDF–542K

Select item 31094816.

DNA Cloning Using In Vitro Site-Specific Recombination

James L. Hartley, Gary F. Temple, Michael A. Brasch

Genome Res. 2000 Nov; 10(11): 1788–1795. doi: 10.1101/gr.143000

PMCID:: PMC310948

Abstract Article PDF–1.7M

Select item 484160717.

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect

Philip J. Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C. Burns, Andrew D. Smith, Luiz O. F. Penalva

RNA Biol. 2016 Apr; 13(4): 400–411. Published online 2016 Jan 13. doi: 10.1080/15476286.2015.1138030

PMCID:: PMC4841607

Abstract Article PDF–1.6M

Select item 326170818.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 816503019.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 13924120.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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