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Select item 49872921.

TMX1 determines cancer cell metabolism as a thiol-based modulator of ER–mitochondria Ca²⁺ flux

Arun Raturi, Tomás Gutiérrez, Carolina Ortiz-Sandoval, Araya Ruangkittisakul, Maria Sol Herrera-Cruz, Jeremy P. Rockley, Kevin Gesson, Dimitar Ourdev, Phing-How Lou, Eliana Lucchinetti, Nasser Tahbaz, Michael Zaugg, Shairaz Baksh, Klaus Ballanyi, Thomas Simmen

J Cell Biol. 2016 Aug 15; 214(4): 433–444. doi: 10.1083/jcb.201512077

PMCID:: PMC4987292

Abstract Article PDF–2.0M

Select item 45916852.

Division of labor among oxidoreductases: TMX1 preferentially acts on transmembrane polypeptides

Giorgia Brambilla Pisoni, Lloyd W. Ruddock, Neil Bulleid, Maurizio Molinari

Mol Biol Cell. 2015 Oct 1; 26(19): 3390–3400. doi: 10.1091/mbc.E15-05-0321

PMCID:: PMC4591685

Abstract Article PDF–1.1M

Select item 35845243.

The Protective Role of the Transmembrane Thioredoxin-Related Protein TMX in Inflammatory Liver Injury

Yoshiyuki Matsuo, Kana Irie, Hiroshi Kiyonari, Hiroaki Okuyama, Hajime Nakamura, Aoi Son, Dorys Adriana Lopez-Ramos, Hai Tian, Shin-Ichi Oka, Katsuya Okawa, Shinae Kizaka-Kondoh, Hiroshi Masutani, Junji Yodoi

Antioxid Redox Signal. 2013 Apr 10; 18(11): 1263–1272. doi: 10.1089/ars.2011.4430

PMCID:: PMC3584524

Abstract Article PDF–784K

Select item 27709434.

Physical and Functional Interaction of Transmembrane Thioredoxin-related Protein with Major Histocompatibility Complex Class I Heavy Chain: Redox-based Protein Quality Control and Its Potential Relevance to Immune Responses

Yoshiyuki Matsuo, Hiroshi Masutani, Aoi Son, Shinae Kizaka-Kondoh, Junji Yodoi

Mol Biol Cell. 2009 Nov 1; 20(21): 4552–4562. doi: 10.1091/mbc.E09-05-0439

PMCID:: PMC2770943

Abstract Article PDF–1.2M

Select item 107814585.

TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer

Na Luo, Zhiqiang Mei, Qiqi Zhang, Hong Tang, Runlan Wan, Anni Deng, Xiaopan Zou, Chaoxiang Lv

Aging (Albany NY) 2023 Dec 31; 15(24): 15064–15083. Published online 2023 Dec 21. doi: 10.18632/aging.205332

Correction in:: Aging (Albany NY). 2024 Jun 30; 16(12): 10666–10667.

PMCID:: PMC10781458

Abstract Article PDF–4.1M

Select item 32935266.

Reductive Activation of Type 2 Ribosome-inactivating Proteins Is Promoted by Transmembrane Thioredoxin-related Protein

Matteo Pasetto, Erika Barison, Monica Castagna, Pietro Della Cristina, Cristina Anselmi, Marco Colombatti

J Biol Chem. 2012 Mar 2; 287(10): 7367–7373. Published online 2012 Jan 6. doi: 10.1074/jbc.M111.316828

PMCID:: PMC3293526

Abstract Article PDF–774K

Select item 104826777.

Identification of an alternative triglyceride biosynthesis pathway

Gian-Luca McLelland, Marta Lopez-Osias, Cristy R. C. Verzijl, Brecht D. Ellenbroek, Rafaela A. Oliveira, Nicolaas J. Boon, Marleen Dekker, Lisa G. van den Hengel, Rahmen Ali, Hans Janssen, Ji-Ying Song, Paul Krimpenfort, Tim van Zutphen, Johan W. Jonker, Thijn R. Brummelkamp

Nature. 2023; 621(7977): 171–178. Published online 2023 Aug 30. doi: 10.1038/s41586-023-06497-4

PMCID:: PMC10482677

Abstract Article PDF–24M

Select item 66699288.

Redox signals at the ER–mitochondria interface control melanoma progression

Xin Zhang, Christine S Gibhardt, Thorsten Will, Hedwig Stanisz, Christina Körbel, Miso Mitkovski, Ioana Stejerean, Sabrina Cappello, David Pacheu‐Grau, Jan Dudek, Nasser Tahbaz, Lucas Mina, Thomas Simmen, Matthias W Laschke, Michael D Menger, Michael P Schön, Volkhard Helms, Barbara A Niemeyer, Peter Rehling, Adina Vultur, Ivan Bogeski

EMBO J. 2019 Aug 1; 38(15): e100871. Published online 2019 Jul 15. doi: 10.15252/embj.2018100871

PMCID:: PMC6669928

Abstract Article PDF–2.9M

Select item 63378759.

The transmembrane protein disulfide isomerase TMX1 negatively regulates platelet responses

Zhenzhen Zhao, Yi Wu, Junsong Zhou, Fengwu Chen, Aizhen Yang, David W. Essex

Blood. 2019 Jan 17; 133(3): 246–251. Prepublished online 2018 Nov 13. doi: 10.1182/blood-2018-04-844480

PMCID:: PMC6337875

Abstract Article

Select item 326155110.

Palmitoylated TMX and calnexin target to the mitochondria-associated membrane

Emily M Lynes, Michael Bui, Megan C Yap, Matthew D Benson, Bobbie Schneider, Lars Ellgaard, Luc G Berthiaume, Thomas Simmen

EMBO J. 2012 Jan 18; 31(2): 457–470. Published online 2011 Nov 1. doi: 10.1038/emboj.2011.384

PMCID:: PMC3261551

Abstract Article PDF–3.5M

Select item 350022611.

The human protein disulfide isomerase gene family

James J Galligan, Dennis R Petersen

Hum Genomics. 2012; 6(1): 6. Published online 2012 Jul 5. doi: 10.1186/1479-7364-6-6

PMCID:: PMC3500226

Abstract Article PDF–852K

Select item 857919512.

Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy

Jun Zheng, Xi Chen, Qiang Liu, Guisheng Zhong, Min Zhuang

J Cell Biol. 2022 Jan 3; 221(1): e202103156. Published online 2021 Nov 8. doi: 10.1083/jcb.202103156

PMCID:: PMC8579195

Abstract Article PDF–6.5M

Select item 953129913.

Regulation of membrane fluidity by RNF145‐triggered degradation of the lipid hydrolase ADIPOR2

Norbert Volkmar, Christian M Gawden‐Bone, James C Williamson, Jonathon Nixon‐Abell, James A West, Peter H St George‐Hyslop, Arthur Kaser, Paul J Lehner

EMBO J. 2022 Oct; 41(19): e110777. Published online 2022 Aug 22. doi: 10.15252/embj.2022110777

PMCID:: PMC9531299

Abstract Article PDF–6.9M

Select item 411063614.

Protein interaction discovery using parallel analysis of translated ORFs (PLATO)

Jian Zhu, H. Benjamin Larman, Geng Gao, Romel Somwar, Zijuan Zhang, Uri Laserson, Alberto Ciccia, Natalya Pavlova, George Church, Wei Zhang, Santosh Kesari, Stephen J. Elledge

Nat Biotechnol. Author manuscript; available in PMC 2014 Jul 25.

Published in final edited form as: Nat Biotechnol. 2013 Apr; 31(4): 331–334. Published online 2013 Mar 17. doi: 10.1038/nbt.2539

PMCID:: PMC4110636

Abstract Article PDF–585K

Select item 676379115.

Systematic Affinity Purification Coupled to Mass Spectrometry Identified p62 as Part of the Cannabinoid Receptor CB2 Interactome

Ahmed Sharaf, Leonore Mensching, Christina Keller, Sebastian Rading, Marina Scheffold, Lysann Palkowitsch, Nevena Djogo, Meriem Rezgaoui, Hans A. Kestler, Barbara Moepps, Antonio Virgilio Failla, Meliha Karsak

Front Mol Neurosci. 2019; 12: 224. Published online 2019 Sep 20. doi: 10.3389/fnmol.2019.00224

PMCID:: PMC6763791

Abstract Article PDF–3.6M

Select item 979335916.

SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis

Saisai Guo, Xiaobo Lei, Yan Chang, Jianyuan Zhao, Jing Wang, Xiaojing Dong, Qian Liu, Zixiong Zhang, Lidan Wang, Dongrong Yi, Ling Ma, Quanjie Li, Yongxin Zhang, Jiwei Ding, Chen Liang, Xiaoyu Li, Fei Guo, Jianwei Wang, Shan Cen

Signal Transduct Target Ther. 2022; 7: 400. Published online 2022 Dec 27. doi: 10.1038/s41392-022-01239-w

PMCID:: PMC9793359

Abstract Article PDF–3.7M

Select item 367060417.

Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma

Xiaoli Yang, Peng Zou, Jun Yao, Dong Yun, Huimin Bao, Ruyun Du, Jing Long, Xian Chen

J Proteome Res. Author manuscript; available in PMC 2013 Jun 3.

Published in final edited form as: J Proteome Res. 2010 Mar 5; 9(3): 1402–1415. doi: 10.1021/pr900932y

PMCID:: PMC3670604

Abstract Article PDF–1.5M

Select item 361543318.

PKCε regulates ATF2 availability to alter mitochondrial permeability following genotoxic stress

Eric Lau, Harriet Kluger, Tal Varsano, KiYoung Lee, Immo Scheffler, David L. Rimm, Trey Ideker, Ze’ev A. Ronai

Cell. Author manuscript; available in PMC 2013 Apr 3.

Published in final edited form as: Cell. 2012 Feb 3; 148(3): 543–555. doi: 10.1016/j.cell.2012.01.016

PMCID:: PMC3615433

Abstract Article PDF–5.3M

Select item 542795019.

Novel, Gel-free Proteomics Approach Identifies RNF5 and JAMP as Modulators of GPCR Stability

Sébastien J. Roy, Irina Glazkova, Louis Fréchette, Christian Iorio-Morin, Chantal Binda, Darlaine Pétrin, Phan Trieu, Mélanie Robitaille, Stéphane Angers, Terence E. Hébert, Jean-Luc Parent

Mol Endocrinol. 2013 Aug; 27(8): 1245–1266. Published online 2013 Jun 24. doi: 10.1210/me.2013-1091