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Select item 64926461.

Signal Peptide Peptidase, Encoded by HM13, Contributes to Tumor Progression by Affecting EGFRvIII Secretion Profiles in Glioblastoma

Jian‐Wei Wei, Jin‐Quan Cai, Chuan Fang, Yan‐Li Tan, Kai Huang, Chao Yang, Qun Chen, Chuan‐Lu Jiang, Chun‐Sheng Kang

CNS Neurosci Ther. 2017 Mar; 23(3): 257–265. Published online 2017 Feb 15. doi: 10.1111/cns.12672

PMCID:: PMC6492646

Article PDF–1.4M

Select item 31382782.

Three-dimensional Structure of the Signal Peptide Peptidase

Hiroyuki Miyashita(宮下紘幸), Yuusuke Maruyama(丸山雄介), Hayato Isshiki(一色隼人), Satoko Osawa(大沢智子), Toshihiko Ogura(小椋俊彦), Kazuhiro Mio(三尾和弘), Chikara Sato(佐藤主税), Taisuke Tomita(富田泰輔), Takeshi Iwatsubo(岩坪威)

J Biol Chem. 2011 Jul 22; 286(29): 26188–26197. Published online 2011 Jun 2. doi: 10.1074/jbc.M111.260273

PMCID:: PMC3138278

Article PDF–1.9M

Select item 1261583.

Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets

John McLauchlan, Marius K. Lemberg, Graham Hope, Bruno Martoglio

EMBO J. 2002 Aug 1; 21(15): 3980–3988. doi: 10.1093/emboj/cdf414

PMCID:: PMC126158

Article PDF–279K

Select item 108509594.

Intramembrane protease SPP defines a cholesterol-regulated abundance control of the mevalonate pathway enzyme squalene synthase

Dönem Avci, Ronny Heidasch, Martina Costa, Christian Lüchtenborg, Dipali Kale, Britta Brügger, Marius K. Lemberg

J Biol Chem. 2024 Feb; 300(2): 105644. Published online 2024 Jan 11. doi: 10.1016/j.jbc.2024.105644

PMCID:: PMC10850959

Article PDF–2.5M

Select item 95093745.

Histocompatibility Minor 13 (HM13), targeted by miR-760, exerts oncogenic role in breast cancer by suppressing autophagy and activating PI3K-AKT-mTOR pathway

Haiyan Yang, Zhi Li, Zhangwei Wang, Xu Zhang, Xinyuan Dai, Guoren Zhou, Qiang Ding

Cell Death Dis. 2022 Aug; 13(8): 728. Published online 2022 Sep 25. doi: 10.1038/s41419-022-05154-4

PMCID:: PMC9509374

Article PDF–6.3M

Select item 56957916.

Insights into the mechanism of isoenzyme-specific signal peptide peptidase-mediated translocation of heme oxygenase

Bianca Schaefer, Kohji Moriishi, Soenke Behrends

PLoS One. 2017; 12(11): e0188344. Published online 2017 Nov 20. doi: 10.1371/journal.pone.0188344

PMCID:: PMC5695791

Article PDF–18M

Select item 59347667.

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins

Sandra Stefanovic‐Barrett, Anna S Dickson, Stephen P Burr, James C Williamson, Ian T Lobb, Dick JH van den Boomen, Paul J Lehner, James A Nathan

EMBO Rep. 2018 May; 19(5): e45603. Published online 2018 Mar 8. doi: 10.15252/embr.201745603

PMCID:: PMC5934766

Article PDF–4.7M

Select item 28244528.

Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation

Seong-Ok Lee, Kwangmin Cho, Sunglim Cho, Ilkwon Kim, Changhoon Oh, Kwangseog Ahn

EMBO J. 2010 Jan 20; 29(2): 363–375. Published online 2009 Nov 26. doi: 10.1038/emboj.2009.359

PMCID:: PMC2824452

Article PDF–1.8M

Select item 27421909.

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER

Helen R. Stagg, Mair Thomas, Dick van den Boomen, Emmanuel J.H.J. Wiertz, Harry A. Drabkin, Robert M. Gemmill, Paul J. Lehner

J Cell Biol. 2009 Sep 7; 186(5): 685–692. doi: 10.1083/jcb.200906110

PMCID:: PMC2742190

Article PDF–3.6M

Select item 264583610.

TRAM1 Participates in Human Cytomegalovirus US2- and US11-mediated Dislocation of an Endoplasmic Reticulum Membrane Glycoprotein

Kristina Oresic, Caroline L. Ng, Domenico Tortorella

J Biol Chem. 2009 Feb 27; 284(9): 5905–5914. doi: 10.1074/jbc.M807568200

PMCID:: PMC2645836

Article PDF–1.0M

Select item 428340711.

Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP1u

Chia-yi Chen, Nicole S Malchus, Beate Hehn, Walter Stelzer, Dönem Avci, Dieter Langosch, Marius K Lemberg

EMBO J. 2014 Nov 3; 33(21): 2492–2506. Published online 2014 Sep 19. doi: 10.15252/embj.201488208

PMCID:: PMC4283407

Article PDF–1.7M

Select item 179662412.

A Screen for Retrotransposed Imprinted Genes Reveals an Association between X Chromosome Homology and Maternal Germ-Line Methylation

Andrew J Wood, Roland G Roberts, David Monk, Gudrun E Moore, Reiner Schulz, Rebecca J Oakey

PLoS Genet. 2007 Feb; 3(2): e20. Prepublished online 2006 Dec 18. Published online 2007 Feb 9. doi: 10.1371/journal.pgen.0030020

PMCID:: PMC1796624

Article PDF–1.1M

Select item 743098313.

Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes

Won Hoon Choi, Yejin Yun, Seoyoung Park, Jun Hyoung Jeon, Jeeyoung Lee, Jung Hoon Lee, Su-A Yang, Nak-Kyoon Kim, Chan Hoon Jung, Yong Tae Kwon, Dohyun Han, Sang Min Lim, Min Jae Lee

Proc Natl Acad Sci U S A. 2020 Aug 11; 117(32): 19190–19200. Published online 2020 Jul 28. doi: 10.1073/pnas.1920327117

PMCID:: PMC7430983

Article PDF–2.2M

Select item 689488514.

NCOA2 promotes lytic reactivation of Kaposi’s sarcoma-associated herpesvirus by enhancing the expression of the master switch protein RTA

Xiaoqin Wei, Lei Bai, Lianghui Dong, Huimei Liu, Peidong Xing, Zhiyao Zhou, Shuwen Wu, Ke Lan

PLoS Pathog. 2019 Nov; 15(11): e1008160. Published online 2019 Nov 21. doi: 10.1371/journal.ppat.1008160

PMCID:: PMC6894885

Article PDF–4.2M

Select item 432443915.

Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

Jeffrey T. Galligan, Gustavo Martinez-Noël, Verena Arndt, Sebastian Hayes, Thomas W. Chittenden, J. Wade Harper, Peter M. Howley

J Proteome Res. 2015 Feb 6; 14(2): 953–966. Published online 2014 Dec 4. doi: 10.1021/pr501005v

PMCID:: PMC4324439

Article PDF–7.5M

Select item 573529716.

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics

Y Li, H Sun, C Zhang, J Liu, H Zhang, F Fan, R A Everley, X Ning, Y Sun, J Hu, J Liu, J Zhang, W Ye, X Qiu, S Dai, B Liu, H Xu, S Fu, S P Gygi, C Zhou

Oncogene. 2017 Dec 14; 36(50): 6839–6849. Published online 2017 Aug 28. doi: 10.1038/onc.2017.289

PMCID:: PMC5735297

Article PDF–1.3M

Select item 486077417.

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair

Patrick Herr, Cecilia Lundin, Bastiaan Evers, Daniel Ebner, Christina Bauerschmidt, Guy Kingham, Timea Palmai-Pallag, Oliver Mortusewicz, Oliver Frings, Erik Sonnhammer, Thomas Helleday

Cell Discov. 2015; 1: 15034. Published online 2015 Dec 1. doi: 10.1038/celldisc.2015.34

PMCID:: PMC4860774

Article PDF–4.1M

Select item 723200918.

Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress

Jiaojiao Yu, Tao Li, Yu Liu, Xi Wang, Jianchao Zhang, Xi'e Wang, Guizhi Shi, Jizhong Lou, Likun Wang, Chih‐chen Wang, Lei Wang

EMBO J. 2020 May 18; 39(10): e103841. Published online 2020 Mar 9. doi: 10.15252/embj.2019103841

PMCID:: PMC7232009

Article PDF–5.5M

Select item 492871619.

HIV–host interactome revealed directly from infected cells

Yang Luo, Erica Y. Jacobs, Todd M. Greco, Kevin D. Mohammed, Tommy Tong, Sarah Keegan, James M. Binley, Ileana M. Cristea, David Fenyö, Michael P. Rout, Brian T. Chait, Mark A. Muesing

Nat Microbiol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Nat Microbiol. 2016 Jul; 1(7): 16068. Published online 2016 May 23. doi: 10.1038/nmicrobiol.2016.68

PMCID:: PMC4928716

Article PDF–1.1M

Select item 568444220.

The interactome of metabolic enzyme carbonic anhydrase IX reveals novel roles in tumor cell migration and invadopodia/MMP14-mediated invasion

M Swayampakula, P C McDonald, M Vallejo, E Coyaud, S C Chafe, A Westerback, G Venkateswaran, J Shankar, G Gao, E M N Laurent, Y Lou, K L Bennewith, C T Supuran, I R Nabi, B Raught, S Dedhar

Oncogene. 2017 Nov 9; 36(45): 6244–6261. Published online 2017 Jul 10. doi: 10.1038/onc.2017.219