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Select item 107981521.

GSDMD suppresses keratinocyte differentiation by inhibiting FLG expression and attenuating KCTD6-mediated HDAC1 degradation in atopic dermatitis

Yi Zhong, Taoyuan Huang, Xiaoli Li, Peiyi Luo, Bingjun Zhang

PeerJ. 2024; 12: e16768. Published online 2024 Jan 16. doi: 10.7717/peerj.16768

PMCID:: PMC10798152

Abstract Article PDF–19M

Select item 106368302.

System analysis based on the pyroptosis-related genes identifes GSDMD as a novel therapy target for skin cutaneous melanoma

Shixin Zhao, Yongkang Zhu, Hengdeng Liu, Xuefeng He, Julin Xie

J Transl Med. 2023; 21: 801. Published online 2023 Nov 10. doi: 10.1186/s12967-023-04513-9

PMCID:: PMC10636830

Abstract Article PDF–9.8M

Select item 104882043.

Gasdermin D (GSDMD) Is Upregulated in Psoriatic Skin—A New Potential Link in the Pathogenesis of Psoriasis

Julia Nowowiejska, Anna Baran, Justyna Magdalena Hermanowicz, Anna Pryczynicz, Beata Sieklucka, Dariusz Pawlak, Iwona Flisiak

Int J Mol Sci. 2023 Sep; 24(17): 13047. Published online 2023 Aug 22. doi: 10.3390/ijms241713047

PMCID:: PMC10488204

Abstract Article PDF–4.0M

Select item 102959694.

Gasdermin D Plays an Oncogenic Role in Glioma and Correlates to an Immunosuppressive Microenvironment

Mengyuan Li, Ping Jiang, Shuhua Wei, Yuhan Yang, Liting Xiong, Junjie Wang, Chunxiao Li

Biomolecules. 2023 Jun; 13(6): 904. Published online 2023 May 29. doi: 10.3390/biom13060904

PMCID:: PMC10295969

Abstract Article PDF–11M

Select item 102329705.

Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors

Zhen Dai, Wan-Cong Liu, Xiao-Yi Chen, Xiao Wang, Jun-Long Li, Xiang Zhang

Front Immunol. 2023; 14: 1178662. Published online 2023 May 18. doi: 10.3389/fimmu.2023.1178662

PMCID:: PMC10232970

Abstract Article PDF–2.3M

Select item 102286256.

Copy number variation of gasdermin D gene is associated with atrial fibrillation-related thromboembolic stroke

Pang-Shuo Huang, Jen-Fang Cheng, Guan-Wei Li, Eric Y Chuang, Jien-Jiun Chen, Fu-Chun Chiu, Cho-Kai Wu, Yi-Chih Wang, Juey-Jen Hwang, Chia-Ti Tsai

Europace. 2023 May; 25(5): euad103. Published online 2023 Apr 21. doi: 10.1093/europace/euad103

PMCID:: PMC10228625

Abstract Article PDF–355K

Select item 99805907.

The Role of Gasdermin-D-Mediated Pryoptosis in Organ Injury and Its Therapeutic Implications

Joud Mulla, Rohan Katti, Melanie J. Scott

Organogenesis. 2023; 19(1): 2177484. Published online 2023 Feb 22. doi: 10.1080/15476278.2023.2177484

PMCID:: PMC9980590

Abstract Article PDF–859K

Select item 97690518.

Elevated circulating levels of gasdermin D are related to acute myocardial infarction and pyrogptosis

Yawen Weng, Bozhi Ye, Jiahui Lin, Shuang Lin, Lingfeng Zhong, Weijian Huang, Xueli Cai, Weiqi Wang

BMC Cardiovasc Disord. 2022; 22: 554. Published online 2022 Dec 21. doi: 10.1186/s12872-022-02998-8

PMCID:: PMC9769051

Abstract Article PDF–898K

Select item 95649239.

New Insights Relating Gasdermin B to the Onset of Childhood Asthma

Nathan Schoettler, Eishika Dissanayake, Mark W. Craven, Jeremiah S. Yee, Joshua Eliason, Eric M. Schauberger, Robert F. Lemanske, Jr., Carole Ober, James E. Gern

Am J Respir Cell Mol Biol. 2022 Oct 1; 67(4): 430–437. Published online 2022 May 17. doi: 10.1165/rcmb.2022-0043PS

PMCID:: PMC9564923

Abstract Article PDF–838K

Select item 942042110.

Translocation of gasdermin D induced mitochondrial injury and mitophagy mediated quality control in lipopolysaccharide related cardiomyocyte injury

Ziqing Yu, Zilong Xiao, Lichun Guan, Pei Bao, Yong Yu, Yixiu Liang, Minghui Li, Zhenzhen Huang, Xueying Chen, Ruizhen Chen, Yangang Su, Junbo Ge

Clin Transl Med. 2022 Aug; 12(8): e1002. Published online 2022 Aug 28. doi: 10.1002/ctm2.1002

PMCID:: PMC9420421

Abstract Article PDF–7.1M

Select item 909037111.

GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases

Rita Sala, Elisa Rioja-Blanco, Naroa Serna, Laura Sánchez-García, Patricia Álamo, Lorena Alba-Castellón, Isolda Casanova, Antonio López-Pousa, Ugutz Unzueta, María Virtudes Céspedes, Esther Vázquez, Antonio Villaverde, Ramon Mangues

Drug Deliv. 2022; 29(1): 1384–1397. Published online 2022 May 9. doi: 10.1080/10717544.2022.2069302

PMCID:: PMC9090371

Abstract Article PDF–3.5M

Select item 883320312.

Electrostatic influence on IL-1 transport through the GSDMD pore

Wen Jun Xie, Shiyu Xia, Arieh Warshel, Hao Wu

Proc Natl Acad Sci U S A. 2022 Feb 8; 119(6): e2120287119. Published online 2022 Feb 3. doi: 10.1073/pnas.2120287119

PMCID:: PMC8833203

Abstract Article PDF–1.4M

Select item 872426613.

GSDMD-mediated pyroptosis: a critical mechanism of diabetic nephropathy

Yi Zuo, Li Chen, Huiping Gu, Xiaoyun He, Zhen Ye, Zhao Wang, Qixiang Shao, Caiping Xue

Expert Rev Mol Med. 2021; 23: e23. Published online 2021 Dec 27. doi: 10.1017/erm.2021.27

PMCID:: PMC8724266

Abstract Article PDF–458K

Select item 857194914.

Establishment and validation of a gasdermin signature to evaluate the immune status and direct risk‐group classification in luminal‐B breast cancer

Chenxuan Yang, Jiaxiang Liu, Shuangtao Zhao, Jianming Ying, Yueping Liu, Li Ma, Qingyao Shang, Xiangzhi Meng, Kexin Feng, Bo Zheng, Changyuan Guo, Xin Wang, Xiang Wang

Clin Transl Med. 2021 Nov; 11(11): e614. Published online 2021 Nov 6. doi: 10.1002/ctm2.614

PMCID:: PMC8571949

Article PDF–3.9M

Select item 834132215.

Gasdermin D: Evidence of Pyroptosis in Spontaneous Preterm Labor with Sterile Intra-amniotic Inflammation or Intra-amniotic Infection

Nardhy Gomez-Lopez, Roberto Romero, Adi L. Tarca, Derek Miller, Bogdan Panaitescu, George Schwenkel, Dereje W. Gudicha, Sonia S. Hassan, Percy Pacora, Eunjung Jung, Chaur-Dong Hsu

Am J Reprod Immunol. Author manuscript; available in PMC 2021 Aug 5.

Published in final edited form as: Am J Reprod Immunol. 2019 Dec; 82(6): e13184. Published online 2019 Sep 20. doi: 10.1111/aji.13184